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Gene: ENSG00000090382 |
Summary for LYZ |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000090382 | Gene symbol | LYZ |
| Gene name | lysozyme | |
| HGNC | 6740 | |
| Entrez ID | 4069 | |
| Gene type | protein_coding | |
| Synonyms | LYZ| | |
| UniProtAcc | P61626 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000090382 | LYZ | DB00128 | Aspartic acid | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB02159 | (R)-Propylene glycol | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB02759 | 4-methyl-umbelliferyl-N-acetyl-chitobiose | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB02772 | Sucrose | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03006 | Arsanilic acid | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03013 | N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03120 | p-Toluenesulfonic acid | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03175 | Propyl alcohol | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03189 | Cu-Cyclam | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03487 | (S)-Aspartimide | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB03967 | Dodecyl sulfate | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB04194 | Triacetylchitotriose | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB04268 | Methylumbelliferyl chitotriose | SmallMoleculeDrug |
| ENSG00000090382 | LYZ | DB06912 | UNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDE | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for LYZ |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LYZ | 9.77e+03 | -1.47e+00 | 4.85e-01 | -3.04e+00 | 2.37e-03 | 2.11e-02 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LYZ | 6.39e+03 | 1.64e+00 | 4.53e-01 | 3.63e+00 | 2.87e-04 | 9.11e-04 | THCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LYZ | 9.27e+03 | 1.37e+00 | 1.64e-01 | 8.34e+00 | 7.43e-17 | 2.20e-16 | BRCA |
Top |
Sex-biased somatic mutation for LYZ |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for LYZ |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg16097772 | chr12:69348452 | CGI:chr12:69359725-69360308 | promoter,exon,CDS,gene body | 4.55e-01 | 3.51e-01 | 3.61e+00 | 3.09e-04 | 1.63e-03 | 1.04e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg16097772 | chr12:69348452 | CGI:chr12:69359725-69360308 | promoter,exon,CDS,gene body | 7.23e-01 | 8.38e-01 | -4.76e+00 | 1.94e-06 | 6.47e-06 | -1.15e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| COAD | cg04785213 | chr12:69349836 | CGI:chr12:69359725-69360308 | promoter,gene body | 7.98e-01 | 9.20e-01 | -2.06e+00 | 3.92e-02 | 4.20e-02 | -1.23e-01 |
Top |
Exon skipping events with PSI in TCGA for LYZ |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for LYZ |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for LYZ |
| TFs related to LYZ. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | ZNF333 | LYZ | 3.15e+00 | 5.06e-03 | 4.58e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF506 | LYZ | 3.06e+00 | 4.24e-03 | 4.55e+00 | 9.87e-01 | Female-biased |
| LGG | ZNF329 | LYZ | 4.56e+00 | 9.84e-01 | 4.08e+00 | 9.38e-03 | Male-biased |
| LGG | ZNF333 | LYZ | 4.58e+00 | 9.88e-01 | 3.99e+00 | 4.99e-03 | Male-biased |
| LGG | ZNF506 | LYZ | 4.25e+00 | 9.83e-01 | 3.68e+00 | 5.53e-03 | Male-biased |
| LGG | ZNF573 | LYZ | 4.57e+00 | 9.87e-01 | 4.03e+00 | 6.68e-03 | Male-biased |
| MESO | ZNF418 | LYZ | 3.86e+00 | 6.13e-03 | 5.29e+00 | 9.92e-01 | Female-biased |
| MESO | ZNF879 | LYZ | 3.64e+00 | 1.36e-02 | 4.82e+00 | 9.82e-01 | Female-biased |
| SKCM | SOX7 | LYZ | 4.60e+00 | 1.43e-02 | 5.46e+00 | 9.82e-01 | Female-biased |
| SKCM | SRY | LYZ | 5.06e+00 | 1.66e-02 | 5.88e+00 | 9.82e-01 | Female-biased |
| SKCM | ZFP82 | LYZ | 4.33e+00 | 1.27e-02 | 5.23e+00 | 9.83e-01 | Female-biased |
| SKCM | ZNF418 | LYZ | 3.55e+00 | 1.37e-03 | 5.15e+00 | 9.93e-01 | Female-biased |
| SKCM | ZNF879 | LYZ | 3.41e+00 | 6.57e-03 | 4.52e+00 | 9.80e-01 | Female-biased |
| LYZ related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for LYZ |
| RBPs related to ES in LYZ. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LYZ related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000090382 | L3MBTL4-AS1,hsa-mir-3613,LYZ | Male-specific ceRNA | TCGA-THCA |
| ENSG00000090382 | SUGCT-AS1,hsa-mir-3613,LYZ | Male-specific ceRNA | TCGA-THCA |
| ENSG00000090382 | LINC00528,hsa-mir-3613,LYZ | Male-specific ceRNA | TCGA-THCA |
| ENSG00000090382 | HOTAIRM1,hsa-mir-3613,LYZ | Male-specific ceRNA | TCGA-THCA |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11174810 | chr12:63146515:C:T | - | 0.260383440513206 | 0.00642256645095095 | KIRP | Female-baised eQTL |
| rs11174816 | chr12:63153868:G:A | - | 0.260383440513206 | 0.00642256645095095 | KIRP | Female-baised eQTL |
| rs11835497 | chr12:63162165:T:C | - | 0.259877512311335 | 0.00682532161042881 | KIRP | Female-baised eQTL |
| rs10877982 | chr12:63174460:C:T | - | 0.259877512311335 | 0.00682532161042881 | KIRP | Female-baised eQTL |
| rs7979692 | chr12:63178690:C:T | - | 0.259877512311335 | 0.00682532161042881 | KIRP | Female-baised eQTL |
| rs11174833 | chr12:63180845:A:G | - | 0.259877512311335 | 0.00682532161042881 | KIRP | Female-baised eQTL |
| rs10161377 | chr12:63187383:G:A | - | 0.259877512311335 | 0.00682532161042881 | KIRP | Female-baised eQTL |
| rs6581472 | chr12:63192089:C:T | - | 0.259877512311335 | 0.00682532161042881 | KIRP | Female-baised eQTL |
| rs1589968 | chr12:75032111:A:G | - | -0.218709147553544 | 0.00721445796049173 | KIRP | Female-baised eQTL |
| rs73334375 | chr12:67650204:A:G | - | 0.252968121607056 | 0.0119179376953716 | KIRP | Female-baised eQTL |
| rs78784912 | chr12:68796137:T:G | - | 0.29318225236467 | 0.0151845361494906 | KIRP | Female-baised eQTL |
| rs4882901 | chr12:73587004:T:C | - | -0.178349871770407 | 0.0160122887386525 | KIRP | Female-baised eQTL |
| rs2363696 | chr12:73569764:G:A | - | -0.178498396893056 | 0.0170622287219561 | KIRP | Female-baised eQTL |
| rs1443721 | chr12:73579478:A:G | - | -0.173315018306158 | 0.0256195472174516 | KIRP | Female-baised eQTL |
| rs7310713 | chr12:73584289:G:A | - | -0.173315018306158 | 0.0256195472174516 | KIRP | Female-baised eQTL |
| rs17098298 | chr12:62776947:T:C | - | 0.218336009661135 | 0.0301625247378209 | KIRP | Female-baised eQTL |
| rs76543787 | chr12:62779191:C:A | - | 0.218336009661135 | 0.0301625247378209 | KIRP | Female-baised eQTL |
| rs17098311 | chr12:62779408:T:C | - | 0.218336009661135 | 0.0301625247378209 | KIRP | Female-baised eQTL |
| rs17098314 | chr12:62779778:G:T | - | 0.218336009661135 | 0.0301625247378209 | KIRP | Female-baised eQTL |
| rs764065 | chr12:73583783:T:C | - | -0.170838068205588 | 0.0321339813557329 | KIRP | Female-baised eQTL |
| rs10877980 | chr12:63174317:A:G | - | 0.228267493935855 | 0.0330047964915537 | KIRP | Female-baised eQTL |
| rs12300214 | chr12:63186297:A:G | - | 0.228267493935855 | 0.0330047964915537 | KIRP | Female-baised eQTL |
| rs2603086 | chr12:69382403:A:G | - | 0.144017002629983 | 0.0345328652932691 | KIRP | Female-baised eQTL |
| rs2603088 | chr12:69382519:A:G | - | 0.144017002629983 | 0.0345328652932691 | KIRP | Female-baised eQTL |
| rs4360761 | chr12:73583469:A:T | - | -0.169400743199928 | 0.0364936474418145 | KIRP | Female-baised eQTL |
| rs6582176 | chr12:73588473:A:G | - | -0.169400743199928 | 0.0364936474418145 | KIRP | Female-baised eQTL |
| rs1596396 | chr12:73564228:C:T | - | -0.169682117358559 | 0.0382964428274123 | KIRP | Female-baised eQTL |
| rs10735984 | chr12:75027258:C:T | - | -0.252858058378491 | 0.0395240717993444 | KIRP | Female-baised eQTL |
| rs1526815 | chr12:75037635:A:G | - | -0.252858058378491 | 0.0395240717993444 | KIRP | Female-baised eQTL |
| rs4842439 | chr12:79173201:T:G | - | 0.267225915245226 | 0.0397918346651928 | KIRP | Female-baised eQTL |
| rs10785052 | chr12:73569603:T:C | - | -0.16745358395212 | 0.0434076309468483 | KIRP | Female-baised eQTL |
| rs894789 | chr12:73591004:T:C | - | -0.166570169361012 | 0.0498499441499717 | KIRP | Female-baised eQTL |
| rs76614245 | chr12:66439915:A:G | - | 0.180560837781857 | 0.0119108789556483 | LIHC | Female-baised eQTL |
| rs76960576 | chr12:66440369:T:A | - | 0.180560837781857 | 0.0119108789556483 | LIHC | Female-baised eQTL |
| rs6581694 | chr12:66432775:A:G | - | -0.177808078044837 | 0.0155707888368894 | LIHC | Female-baised eQTL |
| rs7298638 | chr12:66438822:C:G | - | -0.177808078044837 | 0.0155707888368894 | LIHC | Female-baised eQTL |
| rs7958281 | chr12:66433092:T:C | - | -0.177274206392726 | 0.0166267020345887 | LIHC | Female-baised eQTL |
| rs6581696 | chr12:66433500:G:A | - | -0.177274206392726 | 0.0166267020345887 | LIHC | Female-baised eQTL |
| rs7487886 | chr12:66433846:G:A | - | -0.177274206392726 | 0.0166267020345887 | LIHC | Female-baised eQTL |
| rs6421221 | chr12:66435878:T:C | - | -0.177274206392726 | 0.0166267020345887 | LIHC | Female-baised eQTL |
| rs7307368 | chr12:66403573:A:C | - | 0.27332635472094 | 0.0241457219610995 | LIHC | Female-baised eQTL |
| rs73315128 | chr12:66405485:C:A | - | 0.27332635472094 | 0.0241457219610995 | LIHC | Female-baised eQTL |
| rs73315136 | chr12:66409029:G:A | - | 0.272679082816508 | 0.0251119823250608 | LIHC | Female-baised eQTL |
| rs73315139 | chr12:66409078:A:G | - | 0.272679082816508 | 0.0251119823250608 | LIHC | Female-baised eQTL |
| rs11176171 | chr12:66411353:A:G | - | 0.272679082816508 | 0.0251119823250608 | LIHC | Female-baised eQTL |
| rs60993397 | chr12:66411835:A:C | - | 0.272679082816508 | 0.0251119823250608 | LIHC | Female-baised eQTL |
| rs73315156 | chr12:66414142:G:C | - | 0.272679082816508 | 0.0251119823250608 | LIHC | Female-baised eQTL |
| rs73315160 | chr12:66417449:C:T | - | 0.272679082816508 | 0.0251119823250608 | LIHC | Female-baised eQTL |
| rs60771683 | chr12:66406867:C:A | - | 0.272074974620416 | 0.0261250387568653 | LIHC | Female-baised eQTL |
| rs7484781 | chr12:66436231:A:C | - | -0.154298948274645 | 0.0308187913802299 | LIHC | Female-baised eQTL |
| rs6421220 | chr12:66428747:T:C | - | -0.170331625110944 | 0.0409700569760753 | LIHC | Female-baised eQTL |
| rs11180637 | chr12:75695700:G:C | - | 0.0741669308944373 | 0.00404026367568278 | LUSC | Female-baised eQTL |
| rs4761294 | chr12:69146603:G:A | - | 0.0889785043849183 | 0.0106730958217169 | LUSC | Female-baised eQTL |
| rs28538211 | chr12:63627837:T:C | - | 0.0799025361661643 | 0.0458447952023932 | LUSC | Female-baised eQTL |
| rs140377219 | chr12:63630828:C:T | - | 0.0799025361661643 | 0.0458447952023932 | LUSC | Female-baised eQTL |
| rs1266168 | chr12:63633541:G:A | - | 0.0799079253759771 | 0.046324751446055 | LUSC | Female-baised eQTL |
| rs61936114 | chr12:63640430:A:T | - | 0.0799079253759771 | 0.046324751446055 | LUSC | Female-baised eQTL |
| rs61936116 | chr12:63640940:T:A | - | 0.0799079253759771 | 0.046324751446055 | LUSC | Female-baised eQTL |
| rs4763101 | chr12:63642598:A:G | - | 0.0799079253759771 | 0.046324751446055 | LUSC | Female-baised eQTL |
| rs61936119 | chr12:63644571:C:T | - | 0.0799079253759771 | 0.046324751446055 | LUSC | Female-baised eQTL |
| rs61936121 | chr12:63645335:T:C | - | 0.0799079253759771 | 0.046324751446055 | LUSC | Female-baised eQTL |
| rs1599745 | chr12:69792249:C:T | - | -0.0856999426559695 | 0.0288005852899487 | LGG | Female-baised eQTL |
| rs1353733 | chr12:60802306:G:A | - | 0.0768857653593303 | 0.0382239978124588 | LGG | Female-baised eQTL |
| rs17618290 | chr12:60867618:C:T | - | 0.076023073207808 | 0.0387024639707371 | LGG | Female-baised eQTL |
| rs4758757 | chr12:60846675:T:C | - | 0.0738508751781361 | 0.0488136255759835 | LGG | Female-baised eQTL |
| rs11173570 | chr12:60737045:A:G | - | 0.073752234587268 | 0.0497846101307586 | LGG | Female-baised eQTL |
| rs1498463 | chr12:60760228:T:C | - | 0.073752234587268 | 0.0497846101307586 | LGG | Female-baised eQTL |
| rs79004727 | chr12:78021280:A:G | - | 0.218633914450099 | 0.00162568274201885 | BLCA | Female-baised eQTL |
| rs11107917 | chr12:78028270:T:C | - | 0.178051334220235 | 0.0114950563295982 | BLCA | Female-baised eQTL |
| rs11107918 | chr12:78028532:C:T | - | 0.178051334220235 | 0.0114950563295982 | BLCA | Female-baised eQTL |
| rs60572296 | chr12:62703561:T:C | - | 0.171548079600452 | 0.0132657312153891 | BLCA | Female-baised eQTL |
| rs4763028 | chr12:62708797:T:C | - | 0.17129161697491 | 0.0138380769676107 | BLCA | Female-baised eQTL |
| rs11174611 | chr12:62704741:G:A | - | 0.170047039530999 | 0.0150403041455687 | BLCA | Female-baised eQTL |
| rs4763192 | chr12:62712928:G:A | - | 0.160802367489142 | 0.0483972402978467 | BLCA | Female-baised eQTL |
| rs11174394 | chr12:62243358:T:A | - | 0.0749349059455787 | 0.00651370503028927 | LUAD | Female-baised eQTL |
| rs1920095 | chr12:62228102:G:T | - | -0.0749349059455787 | 0.00651370503028927 | LUAD | Female-baised eQTL |
| rs2700269 | chr12:62237476:A:G | - | -0.0749349059455787 | 0.00651370503028927 | LUAD | Female-baised eQTL |
| rs11612691 | chr12:63498737:C:T | - | 0.0468829510440757 | 0.00766443505454982 | LUAD | Female-baised eQTL |
| rs61935001 | chr12:63543812:C:T | - | 0.0827655029879056 | 0.0223644428497097 | LUAD | Female-baised eQTL |
| rs1245653 | chr12:62206852:T:C | - | -0.0639390117500556 | 0.0272911279192448 | LUAD | Female-baised eQTL |
| rs1920091 | chr12:62189849:C:T | - | -0.0629581038118767 | 0.0323499660380147 | LUAD | Female-baised eQTL |
| rs1245642 | chr12:62211536:T:C | - | -0.0623553961480119 | 0.0354614308479512 | LUAD | Female-baised eQTL |
| rs10450792 | chr12:63280234:G:C | - | 0.035919717374258 | 0.0355184100824226 | LUAD | Female-baised eQTL |
| rs1245638 | chr12:62198178:C:T | - | -0.061070770045576 | 0.0366341539020226 | LUAD | Female-baised eQTL |
| rs10450776 | chr12:63280885:A:T | - | 0.0351939250829483 | 0.0405592875658043 | LUAD | Female-baised eQTL |
| rs10784354 | chr12:63282224:C:T | - | 0.0351939250829483 | 0.0405592875658043 | LUAD | Female-baised eQTL |
| rs10784355 | chr12:63284898:A:C | - | 0.0351939250829483 | 0.0405592875658043 | LUAD | Female-baised eQTL |
| rs10878032 | chr12:63285527:T:A | - | 0.0351939250829483 | 0.0405592875658043 | LUAD | Female-baised eQTL |
| rs1245647 | chr12:62209269:A:G | - | -0.0599262547653891 | 0.0413342872790936 | LUAD | Female-baised eQTL |
| rs1245655 | chr12:62205234:T:C | - | -0.0597268031188049 | 0.0428306058887468 | LUAD | Female-baised eQTL |
| rs1245662 | chr12:62201921:T:G | - | -0.05959814414552 | 0.0438860253114127 | LUAD | Female-baised eQTL |
| rs1245657 | chr12:62203744:A:G | - | -0.05959814414552 | 0.0438860253114127 | LUAD | Female-baised eQTL |
| rs1909327 | chr12:63280188:C:T | - | 0.0350050239254015 | 0.0441374054646317 | LUAD | Female-baised eQTL |
| rs1456037 | chr12:63282937:A:G | - | 0.0345783876946115 | 0.0464116623758923 | LUAD | Female-baised eQTL |
| rs4763076 | chr12:63284154:T:C | - | 0.0345500438177448 | 0.0467664614769983 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs56803992 | chr12:75112060:A:G | - | 0.181201363808086 | 0.0190587988548521 | THCA | Male-baised eQTL |
| rs73355607 | chr12:75119458:A:G | - | 0.181201363808086 | 0.0190587988548521 | THCA | Male-baised eQTL |
| rs2278188 | chr12:74292794:T:G | - | 0.122809259288303 | 0.0387564401221082 | THCA | Male-baised eQTL |
| rs73355606 | chr12:75118327:A:G | - | 0.184143040295872 | 0.0406981209740163 | THCA | Male-baised eQTL |
| rs17114645 | chr12:75115254:A:G | - | 0.183651619073325 | 0.0427884172578272 | THCA | Male-baised eQTL |
| rs118119683 | chr12:74661994:T:G | - | 0.18663386093368 | 0.0436169192034385 | THCA | Male-baised eQTL |
| rs4883504 | chr12:74152431:A:T | - | 0.0612779724852605 | 0.0315920799963219 | KIRC | Male-baised eQTL |
| rs74962680 | chr12:67135694:G:A | - | 0.055023011037406 | 0.0332553438629766 | KIRC | Male-baised eQTL |
| rs17781088 | chr12:67092571:G:A | - | 0.0538504118531763 | 0.0452857271853291 | KIRC | Male-baised eQTL |
| rs876420 | chr12:66902174:C:T | - | 0.076804018534432 | 6.30688747335713e-05 | LUAD | Male-baised eQTL |
| rs11176935 | chr12:67906708:C:T | - | 0.0609667594651433 | 0.00206290120850971 | LUAD | Male-baised eQTL |
| rs138914668 | chr12:67902068:C:T | - | 0.0609709570893496 | 0.0020688909059811 | LUAD | Male-baised eQTL |
| rs148011778 | chr12:67903021:G:A | - | 0.0609709570893496 | 0.0020688909059811 | LUAD | Male-baised eQTL |
| rs6581783 | chr12:67915634:C:T | - | 0.0591633297508134 | 0.00298209857579002 | LUAD | Male-baised eQTL |
| rs61024736 | chr12:67896796:G:A | - | 0.0589323966134557 | 0.00323273933790786 | LUAD | Male-baised eQTL |
| rs56409231 | chr12:67894063:T:C | - | 0.0551897295745827 | 0.00583514237750007 | LUAD | Male-baised eQTL |
| rs118090913 | chr12:67425282:T:C | - | 0.0617022532232406 | 0.0074884787530784 | LUAD | Male-baised eQTL |
| rs60117312 | chr12:67157881:T:G | - | 0.050100205193816 | 0.0083987290151623 | LUAD | Male-baised eQTL |
| rs12300697 | chr12:67157987:C:T | - | 0.050100205193816 | 0.0083987290151623 | LUAD | Male-baised eQTL |
| rs12300928 | chr12:67158360:C:G | - | 0.050100205193816 | 0.0083987290151623 | LUAD | Male-baised eQTL |
| rs7302291 | chr12:67159565:G:A | - | 0.050100205193816 | 0.0083987290151623 | LUAD | Male-baised eQTL |
| rs12317689 | chr12:67163000:G:A | - | 0.050100205193816 | 0.0083987290151623 | LUAD | Male-baised eQTL |
| rs10878690 | chr12:67891454:T:C | - | 0.0517373721646485 | 0.0110204372307302 | LUAD | Male-baised eQTL |
| rs2870935 | chr12:67436715:C:T | - | 0.059244188325873 | 0.0111281915202089 | LUAD | Male-baised eQTL |
| rs1808019 | chr12:67153047:A:G | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs59178064 | chr12:67153723:C:T | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs61555627 | chr12:67153828:G:C | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs61918971 | chr12:67154161:A:G | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs61918973 | chr12:67154982:C:T | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs12308753 | chr12:67155741:A:C | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs61918975 | chr12:67156095:T:C | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs12318312 | chr12:67160792:A:G | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs61919004 | chr12:67166085:C:T | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs76999279 | chr12:67168554:A:C | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs11176610 | chr12:67168720:C:A | - | 0.0478781629194877 | 0.0130481333895608 | LUAD | Male-baised eQTL |
| rs11175630 | chr12:65029973:G:T | - | 0.0554297827497577 | 0.0139414605616397 | LUAD | Male-baised eQTL |
| rs7134547 | chr12:67147622:T:G | - | 0.0468527630447311 | 0.0158101856379527 | LUAD | Male-baised eQTL |
| rs11176602 | chr12:67148947:A:G | - | 0.0468527630447311 | 0.0158101856379527 | LUAD | Male-baised eQTL |
| rs11176603 | chr12:67149003:T:C | - | 0.0468527630447311 | 0.0158101856379527 | LUAD | Male-baised eQTL |
| rs11176604 | chr12:67149365:C:T | - | 0.0468527630447311 | 0.0158101856379527 | LUAD | Male-baised eQTL |
| rs61918967 | chr12:67149996:T:C | - | 0.0468527630447311 | 0.0158101856379527 | LUAD | Male-baised eQTL |
| rs117224457 | chr12:67427446:C:A | - | 0.0569322272766998 | 0.0161416013643475 | LUAD | Male-baised eQTL |
| rs117618469 | chr12:67427522:A:T | - | 0.0569322272766998 | 0.0161416013643475 | LUAD | Male-baised eQTL |
| rs1437496 | chr12:67147976:A:G | - | 0.0462530233450656 | 0.016986086414075 | LUAD | Male-baised eQTL |
| rs10437971 | chr12:67233032:A:T | - | 0.0557476605519566 | 0.0182351406872911 | LUAD | Male-baised eQTL |
| rs117408468 | chr12:67423832:T:A | - | 0.0554649600569076 | 0.0191684379299066 | LUAD | Male-baised eQTL |
| rs2620722 | chr12:64613758:C:T | - | 0.0529388581482401 | 0.0243720121620153 | LUAD | Male-baised eQTL |
| rs113373353 | chr12:64613902:C:T | - | 0.0529388581482401 | 0.0243720121620153 | LUAD | Male-baised eQTL |
| rs11175490 | chr12:64641065:A:G | - | 0.04529606183982 | 0.0274394228725035 | LUAD | Male-baised eQTL |
| rs73326489 | chr12:67427596:G:A | - | 0.0531746722950001 | 0.0281622618978193 | LUAD | Male-baised eQTL |
| rs1795616 | chr12:64612578:C:T | - | 0.0511926674442289 | 0.0323618553206827 | LUAD | Male-baised eQTL |
| rs12231334 | chr12:71596825:A:T | - | 0.0426331733243706 | 0.0357024046866999 | LUAD | Male-baised eQTL |
| rs113978873 | chr12:67990781:A:G | - | 0.0467791408187673 | 0.0365966387153237 | LUAD | Male-baised eQTL |
| rs10878686 | chr12:67884376:C:T | - | 0.0442991813129412 | 0.0372626525030204 | LUAD | Male-baised eQTL |
| rs12366841 | chr12:66471921:A:G | - | 0.0376749188606294 | 0.0431982886693829 | LUAD | Male-baised eQTL |
| rs10878187 | chr12:64541966:C:T | - | 0.0385134932578196 | 0.0432454615142286 | LUAD | Male-baised eQTL |
| rs10878189 | chr12:64545770:A:C | - | 0.0385134932578196 | 0.0432454615142286 | LUAD | Male-baised eQTL |
| rs4964110 | chr12:64537043:C:T | - | 0.0383808175091292 | 0.0447139875591381 | LUAD | Male-baised eQTL |
| rs80227918 | chr12:66484556:T:C | - | 0.0376438998403229 | 0.046320888888004 | LUAD | Male-baised eQTL |
| rs77234803 | chr12:69430401:A:G | - | 0.0551890229438904 | 0.0362274735656955 | COAD | Male-baised eQTL |
| rs7964442 | chr12:73840460:T:C | - | 0.0772189114164038 | 0.0377469008449488 | COAD | Male-baised eQTL |
| rs59603592 | chr12:69429056:C:T | - | 0.0535979331834039 | 0.0428200822031265 | COAD | Male-baised eQTL |
| rs60964256 | chr12:69421371:A:G | - | 0.0519121433426507 | 0.0455634189531383 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000090382 |
| CpG Site: cg16097772 | |
| Position to Gene: gene,exon,CDS,promoter | |
| Male Effect: -0.488421593365094 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg16097772 | chr12:69348452 | gene,exon,CDS,promoter | -0.488421593365094 | 4.48044530586044e-85 | -0.9181481097955145 | 8.205914496066925e-91 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of LYZ |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000090382 | LYZ | C0268389 | Amyloidosis, familial visceral | 1 | CTD_human |
