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Gene: ENSG00000084731 |
Summary for KIF3C |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000084731 | Gene symbol | KIF3C |
| Gene name | kinesin family member 3C | |
| HGNC | 6321 | |
| Entrez ID | 3797 | |
| Gene type | protein_coding | |
| Synonyms | KIF3C| | |
| UniProtAcc | O14782 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for KIF3C |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| KIF3C | 7.70e+02 | -1.01e+00 | 1.30e-01 | -7.79e+00 | 6.51e-15 | 1.22e-12 | KIRP |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| KIF3C | 9.30e+02 | 1.22e+00 | 2.38e-01 | 5.13e+00 | 2.94e-07 | 1.13e-06 | LUAD |
| KIF3C | 1.50e+03 | 1.03e+00 | 3.95e-01 | 2.60e+00 | 9.37e-03 | 3.58e-02 | ESCA |
| KIF3C | 9.47e+02 | 3.22e+00 | 5.91e-01 | 5.44e+00 | 5.28e-08 | 5.10e-07 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| KIF3C | 1.28e+03 | 1.29e+00 | 3.39e-01 | 3.80e+00 | 1.45e-04 | 1.09e-03 | KIRP |
Top |
Sex-biased somatic mutation for KIF3C |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for KIF3C |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| ESCA | cg21187770 | chr2:25983007 | CGI:chr2:25981685-25982780 | promoter | 6.76e-01 | 5.65e-01 | 2.13e+00 | 3.29e-02 | 4.50e-02 | 1.11e-01 |
| ACC | cg22898783 | chr2:25981830 | CGI:chr2:25981685-25982780 | promoter,exon,CDS,gene body | 1.24e-01 | 2.34e-01 | -2.42e+00 | 1.55e-02 | 3.18e-02 | -1.09e-01 |
| DLBC | cg07596494 | chr2:25982226 | CGI:chr2:25981685-25982780 | UTR,promoter,exon,gene body | 9.78e-02 | 2.06e-01 | -2.13e+00 | 3.31e-02 | 4.38e-02 | -1.09e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg11277966 | chr2:25983357 | CGI:chr2:25981685-25982780 | promoter | 8.12e-01 | 9.19e-01 | -3.41e+00 | 6.38e-04 | 1.94e-03 | -1.07e-01 |
| COAD | cg05159145 | chr2:25982624 | CGI:chr2:25981685-25982780 | UTR,promoter,exon,gene body | 1.90e-01 | 7.14e-02 | 4.92e+00 | 8.64e-07 | 1.09e-05 | 1.18e-01 |
| ESCA | cg21187770 | chr2:25983007 | CGI:chr2:25981685-25982780 | promoter | 5.65e-01 | 3.89e-01 | 2.07e+00 | 3.80e-02 | 4.61e-02 | 1.76e-01 |
| CHOL | cg22898783 | chr2:25981830 | CGI:chr2:25981685-25982780 | promoter,exon,CDS,gene body | 2.38e-01 | 4.66e-01 | -2.58e+00 | 9.87e-03 | 2.15e-02 | -2.28e-01 |
| CHOL | cg07596494 | chr2:25982226 | CGI:chr2:25981685-25982780 | UTR,promoter,exon,gene body | 7.97e-02 | 2.07e-01 | -3.54e+00 | 4.02e-04 | 8.32e-03 | -1.27e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg07751331 | chr2:25982996 | CGI:chr2:25981685-25982780 | promoter | 4.59e-01 | 2.74e-01 | 8.41e+00 | 4.00e-17 | 1.72e-16 | 1.85e-01 |
| BRCA | cg21187770 | chr2:25983007 | CGI:chr2:25981685-25982780 | promoter | 5.32e-01 | 3.43e-01 | 7.73e+00 | 1.06e-14 | 3.77e-14 | 1.89e-01 |
Top |
Exon skipping events with PSI in TCGA for KIF3C |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for KIF3C |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for KIF3C |
| TFs related to KIF3C. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KIF3C related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for KIF3C |
| RBPs related to ES in KIF3C. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| GBM | EIF4B | exon_skip_337549 | 1.05e+01 | 9.90e-01 | 1.02e+01 | 9.14e-03 | Male-biased |
| KIF3C related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000084731 | AC048341.1,hsa-mir-133b,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | Z95331.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | Z92544.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AC010536.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AC116351.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | FAM225B,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AL138720.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AC019205.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | LHFPL3-AS2,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AC007066.2,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AC232271.1,hsa-mir-485,KIF3C | Female-specific ceRNA | TCGA-LIHC |
| ENSG00000084731 | AC074117.1,hsa-mir-485,KIF3C | Male-specific ceRNA | TCGA-LUAD |
| ENSG00000084731 | MIR4435-2HG,hsa-mir-485,KIF3C | Male-specific ceRNA | TCGA-LUAD |
| ENSG00000084731 | ZFAND2A-DT,hsa-mir-485,KIF3C | Male-specific ceRNA | TCGA-LUAD |
| ENSG00000084731 | AC016065.1,hsa-mir-485,KIF3C | Male-specific ceRNA | TCGA-LUAD |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2384039 | chr2:24710234:T:C | - | -0.0900828639734012 | 0.000371862496306771 | KIRC | Female-baised eQTL |
| rs12616487 | chr2:24701966:T:C | - | -0.0893296916082141 | 0.00258230201182504 | KIRC | Female-baised eQTL |
| rs12468225 | chr2:24699490:C:A | - | -0.0867629437302281 | 0.00328285362420147 | KIRC | Female-baised eQTL |
| rs1025781 | chr2:24689685:G:C | - | -0.0863663171603141 | 0.00355393305070952 | KIRC | Female-baised eQTL |
| rs6531103 | chr2:18448744:T:G | - | 0.110092166605072 | 0.00395522454253355 | KIRC | Female-baised eQTL |
| rs329801 | chr2:21994607:T:C | - | 0.120790085781884 | 0.00441943756478341 | KIRC | Female-baised eQTL |
| rs6739622 | chr2:24630845:G:C | - | -0.0851165403228332 | 0.00459414748306763 | KIRC | Female-baised eQTL |
| rs7566760 | chr2:24564899:G:C | - | -0.0818803903305704 | 0.00651875676054716 | KIRC | Female-baised eQTL |
| rs57167296 | chr2:22101763:A:G | - | 0.120973284792779 | 0.0164235721822702 | KIRC | Female-baised eQTL |
| rs399845 | chr2:22085899:T:A | - | 0.12611421060522 | 0.0188446520165206 | KIRC | Female-baised eQTL |
| rs6722027 | chr2:26415454:T:C | - | -0.0827957331870693 | 0.0201977104768738 | KIRC | Female-baised eQTL |
| rs1829284 | chr2:22072907:G:A | - | 0.119528435170573 | 0.0231290871025147 | KIRC | Female-baised eQTL |
| rs72913413 | chr2:22073551:T:C | - | 0.119528435170573 | 0.0231290871025147 | KIRC | Female-baised eQTL |
| rs6543654 | chr2:22086675:T:C | - | 0.119528435170573 | 0.0231290871025147 | KIRC | Female-baised eQTL |
| rs6709372 | chr2:22091494:C:A | - | 0.119528435170573 | 0.0231290871025147 | KIRC | Female-baised eQTL |
| rs11125730 | chr2:24641132:A:C | - | -0.0792031610719307 | 0.0273500155709149 | KIRC | Female-baised eQTL |
| rs402062 | chr2:22102756:T:C | - | 0.107176607400141 | 0.0320540301918509 | KIRC | Female-baised eQTL |
| rs17044998 | chr2:23251629:A:C | - | 0.15963472919698 | 0.0337542194155341 | KIRC | Female-baised eQTL |
| rs11126483 | chr2:26441459:C:T | - | -0.0752323527487403 | 0.036283709949197 | KIRC | Female-baised eQTL |
| rs59163731 | chr2:22099781:G:A | - | 0.111712464691583 | 0.0369724614515109 | KIRC | Female-baised eQTL |
| rs35444670 | chr2:23252602:C:T | - | 0.154087458670821 | 0.0384360967049627 | KIRC | Female-baised eQTL |
| rs35492358 | chr2:23252116:T:A | - | 0.153907300348081 | 0.0388591720698945 | KIRC | Female-baised eQTL |
| rs13028027 | chr2:23252431:A:T | - | 0.153907300348081 | 0.0388591720698945 | KIRC | Female-baised eQTL |
| rs13028319 | chr2:23252594:A:G | - | 0.153907300348081 | 0.0388591720698945 | KIRC | Female-baised eQTL |
| rs392216 | chr2:22100627:T:C | - | 0.10731028132153 | 0.0412243012298344 | KIRC | Female-baised eQTL |
| rs364963 | chr2:22100936:A:G | - | 0.10731028132153 | 0.0412243012298344 | KIRC | Female-baised eQTL |
| rs7584174 | chr2:18216042:G:A | - | -0.117251263569101 | 0.042017741743977 | KIRC | Female-baised eQTL |
| rs7579878 | chr2:22066558:C:A | - | 0.112782265256524 | 0.0428112639008011 | KIRC | Female-baised eQTL |
| rs6742413 | chr2:22069904:C:T | - | 0.112782265256524 | 0.0428112639008011 | KIRC | Female-baised eQTL |
| rs446052 | chr2:22060276:T:C | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs401045 | chr2:22060949:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs585953 | chr2:22061498:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328560 | chr2:22066857:A:G | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328570 | chr2:22070659:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs2339406 | chr2:22073447:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328546 | chr2:22075081:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs167880 | chr2:22076298:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs172925 | chr2:22076489:T:C | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs186624 | chr2:22077339:C:G | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328545 | chr2:22077371:T:C | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328544 | chr2:22077804:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs610881 | chr2:22083857:G:A | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328525 | chr2:22085305:T:G | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328527 | chr2:22086262:G:C | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs328529 | chr2:22088123:C:A | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs435511 | chr2:22091491:T:A | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs383839 | chr2:22091651:C:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs417634 | chr2:22095239:A:T | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs430047 | chr2:22095754:G:A | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs369591 | chr2:22098527:T:C | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs434091 | chr2:22100278:C:A | - | 0.107685301179856 | 0.0444176714943443 | KIRC | Female-baised eQTL |
| rs62117055 | chr2:16439478:C:T | - | 0.108809003859098 | 0.0444947092136201 | KIRC | Female-baised eQTL |
| rs328518 | chr2:22051231:G:A | - | 0.105096274320086 | 0.0464529043933153 | KIRC | Female-baised eQTL |
| rs56900434 | chr2:20546286:T:C | - | 0.0571394558357026 | 0.000849223137741235 | LUAD | Female-baised eQTL |
| rs73918397 | chr2:19842546:G:T | - | 0.0659267973889397 | 0.00152608235786312 | LUAD | Female-baised eQTL |
| rs59862470 | chr2:20523425:G:T | - | 0.0541544644395457 | 0.00532141384919499 | LUAD | Female-baised eQTL |
| rs77401306 | chr2:25092424:T:A | - | 0.0512576082383604 | 0.00545363584101229 | LUAD | Female-baised eQTL |
| rs7566506 | chr2:25196604:C:A | - | 0.0490013144507204 | 0.00651773662118005 | LUAD | Female-baised eQTL |
| rs483033 | chr2:16783096:T:C | - | 0.0471360753979353 | 0.00706163667540429 | LUAD | Female-baised eQTL |
| rs61742608 | chr2:18584857:C:T | - | 0.0515860806003854 | 0.00772019695701769 | LUAD | Female-baised eQTL |
| rs17044546 | chr2:22990257:C:T | - | 0.0508071215906343 | 0.00839600654048686 | LUAD | Female-baised eQTL |
| rs78141790 | chr2:22990497:C:A | - | 0.0508071215906343 | 0.00839600654048686 | LUAD | Female-baised eQTL |
| rs12620596 | chr2:22984173:A:G | - | 0.0491271912248738 | 0.0123569490551178 | LUAD | Female-baised eQTL |
| rs6545970 | chr2:25137894:G:A | - | 0.0514019526637461 | 0.0128018952889931 | LUAD | Female-baised eQTL |
| rs7580073 | chr2:33652404:A:G | - | 0.0442051215735199 | 0.0131012684206849 | LUAD | Female-baised eQTL |
| rs13399239 | chr2:22994349:G:C | - | 0.0453809426921394 | 0.0136430163496009 | LUAD | Female-baised eQTL |
| rs72850895 | chr2:25094800:A:T | - | 0.0442260736605196 | 0.0162178680459115 | LUAD | Female-baised eQTL |
| rs10165163 | chr2:25084613:C:T | - | 0.0441631611547727 | 0.0165582797691249 | LUAD | Female-baised eQTL |
| rs918897 | chr2:21602988:A:G | - | -0.046252765342878 | 0.0178202289238441 | LUAD | Female-baised eQTL |
| rs62117055 | chr2:16439478:C:T | - | 0.0522265474552534 | 0.0185243146615476 | LUAD | Female-baised eQTL |
| rs6545951 | chr2:25120256:C:T | - | 0.0445350512055117 | 0.0191009156815587 | LUAD | Female-baised eQTL |
| rs7596142 | chr2:23550095:A:G | - | 0.0434260631874135 | 0.0196931420247852 | LUAD | Female-baised eQTL |
| rs2005373 | chr2:33551248:G:C | - | 0.0495782158502678 | 0.0199241080572637 | LUAD | Female-baised eQTL |
| rs6742730 | chr2:25104902:A:C | - | 0.0431774436660076 | 0.0199995385957529 | LUAD | Female-baised eQTL |
| rs6742181 | chr2:25143380:C:T | - | 0.0454208862035728 | 0.0204522637237546 | LUAD | Female-baised eQTL |
| rs76722503 | chr2:25146717:A:T | - | 0.0454208862035728 | 0.0204522637237546 | LUAD | Female-baised eQTL |
| rs74559821 | chr2:25127303:G:A | - | 0.0441162838316953 | 0.0210738292443633 | LUAD | Female-baised eQTL |
| rs114255118 | chr2:25128896:C:T | - | 0.0441162838316953 | 0.0210738292443633 | LUAD | Female-baised eQTL |
| rs6731410 | chr2:33647420:A:G | - | 0.0537083107881105 | 0.023383890351663 | LUAD | Female-baised eQTL |
| rs6718017 | chr2:33647483:T:C | - | 0.0537083107881105 | 0.023383890351663 | LUAD | Female-baised eQTL |
| rs6725572 | chr2:33651094:A:G | - | 0.0537083107881105 | 0.023383890351663 | LUAD | Female-baised eQTL |
| rs72869110 | chr2:33639592:A:T | - | 0.0529900955548964 | 0.0239911342780272 | LUAD | Female-baised eQTL |
| rs10199608 | chr2:33641029:G:C | - | 0.0529900955548964 | 0.0239911342780272 | LUAD | Female-baised eQTL |
| rs10189754 | chr2:33645599:A:G | - | 0.0534884233958878 | 0.0244482912773609 | LUAD | Female-baised eQTL |
| rs7565606 | chr2:33646969:T:G | - | 0.0534884233958878 | 0.0244482912773609 | LUAD | Female-baised eQTL |
| rs6760064 | chr2:33647327:G:A | - | 0.0534884233958878 | 0.0244482912773609 | LUAD | Female-baised eQTL |
| rs59014575 | chr2:25173083:G:A | - | 0.041930605006931 | 0.0246620776888826 | LUAD | Female-baised eQTL |
| rs78560959 | chr2:25173911:C:T | - | 0.041930605006931 | 0.0246620776888826 | LUAD | Female-baised eQTL |
| rs112121079 | chr2:35771788:A:G | - | 0.0428022143759855 | 0.0267979734691751 | LUAD | Female-baised eQTL |
| rs1565326 | chr2:28334213:C:T | - | -0.0364556736782607 | 0.027002778776686 | LUAD | Female-baised eQTL |
| rs3810834 | chr2:17917271:G:T | - | -0.0442416949433767 | 0.0277039404956325 | LUAD | Female-baised eQTL |
| rs3810835 | chr2:17917314:C:T | - | -0.0442416949433767 | 0.0277039404956325 | LUAD | Female-baised eQTL |
| rs76709404 | chr2:25127427:C:G | - | 0.0424944212037339 | 0.0280859712670628 | LUAD | Female-baised eQTL |
| rs1220215 | chr2:34588952:T:A | - | 0.0292607702108301 | 0.0283568495971196 | LUAD | Female-baised eQTL |
| rs3754862 | chr2:25170885:G:A | - | 0.0416298064197027 | 0.0286352026499334 | LUAD | Female-baised eQTL |
| rs116074763 | chr2:25137327:G:A | - | 0.0436416105422123 | 0.0295767155101716 | LUAD | Female-baised eQTL |
| rs17039879 | chr2:25148608:G:A | - | 0.0436416105422123 | 0.0295767155101716 | LUAD | Female-baised eQTL |
| rs6719226 | chr2:25173143:C:G | - | 0.0399455478041122 | 0.0299981544891411 | LUAD | Female-baised eQTL |
| rs77694125 | chr2:28263470:A:G | - | 0.0555870294350078 | 0.0311500231226869 | LUAD | Female-baised eQTL |
| rs7591899 | chr2:25166290:G:A | - | 0.0462401551743718 | 0.0313099223739829 | LUAD | Female-baised eQTL |
| rs6431748 | chr2:15997396:C:T | - | -0.0366217646398719 | 0.0328643031050644 | LUAD | Female-baised eQTL |
| rs6713396 | chr2:25161836:T:C | - | 0.0457784980559739 | 0.0347454282073297 | LUAD | Female-baised eQTL |
| rs16982799 | chr2:16787649:A:T | - | 0.043544342500741 | 0.0348305245398109 | LUAD | Female-baised eQTL |
| rs4666088 | chr2:28534089:A:G | - | -0.0353290962436626 | 0.035001631465133 | LUAD | Female-baised eQTL |
| rs77487086 | chr2:25205433:T:C | - | 0.0446675202915665 | 0.035278677905378 | LUAD | Female-baised eQTL |
| rs11680168 | chr2:28548757:T:G | - | -0.0409402011089736 | 0.0385054901443765 | LUAD | Female-baised eQTL |
| rs4666092 | chr2:28550904:A:G | - | -0.0409402011089736 | 0.0385054901443765 | LUAD | Female-baised eQTL |
| rs4666090 | chr2:28543925:A:G | - | -0.0409621619546415 | 0.0385541576302956 | LUAD | Female-baised eQTL |
| rs7600983 | chr2:28544183:G:A | - | -0.0409621619546415 | 0.0385541576302956 | LUAD | Female-baised eQTL |
| rs6547858 | chr2:28551647:G:C | - | -0.0433877422359104 | 0.0388600195272112 | LUAD | Female-baised eQTL |
| rs7608298 | chr2:28545910:G:A | - | -0.0408681825216849 | 0.0392953698070553 | LUAD | Female-baised eQTL |
| rs12714236 | chr2:28546682:T:C | - | -0.0408681825216849 | 0.0392953698070553 | LUAD | Female-baised eQTL |
| rs1220214 | chr2:34589007:A:C | - | 0.0282839359496617 | 0.0395471821341274 | LUAD | Female-baised eQTL |
| rs1024924 | chr2:16657232:G:A | - | 0.0425219441014573 | 0.0398745873011023 | LUAD | Female-baised eQTL |
| rs6751548 | chr2:35773284:C:T | - | 0.0401022862400592 | 0.0444099323423109 | LUAD | Female-baised eQTL |
| rs1220210 | chr2:34589686:A:C | - | 0.026839973715023 | 0.0460405334122784 | LUAD | Female-baised eQTL |
| rs13032567 | chr2:35772454:G:T | - | 0.0395753427533663 | 0.0476876747283048 | LUAD | Female-baised eQTL |
| rs10495844 | chr2:35774128:C:T | - | 0.0395753427533663 | 0.0476876747283048 | LUAD | Female-baised eQTL |
| rs35041107 | chr2:35774823:T:C | - | 0.0395753427533663 | 0.0476876747283048 | LUAD | Female-baised eQTL |
| rs1220211 | chr2:34589451:T:C | - | 0.0277884735620117 | 0.0486246108342748 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17012090 | chr2:32688197:T:C | - | 0.186592950795868 | 0.000263378870587284 | THCA | Male-baised eQTL |
| rs7575590 | chr2:32728530:T:C | - | 0.165547851839848 | 0.00801035670380919 | THCA | Male-baised eQTL |
| rs1987039 | chr2:22919529:G:T | - | 0.0993814758881477 | 0.0299162637219325 | THCA | Male-baised eQTL |
| rs1148965 | chr2:26598037:C:T | - | -0.0739888794152978 | 0.00865997666655258 | LUAD | Male-baised eQTL |
| rs1148963 | chr2:26595153:C:T | - | -0.0796098047034959 | 0.00927619997227828 | LUAD | Male-baised eQTL |
| rs7560683 | chr2:26592991:C:T | - | 0.0800881195175501 | 0.0126293534021165 | LUAD | Male-baised eQTL |
| rs1148967 | chr2:26598968:C:A | - | -0.0698462459243146 | 0.0158692440043097 | LUAD | Male-baised eQTL |
| rs13415500 | chr2:34495799:C:A | - | 0.112528795752417 | 0.0167366651217323 | LUAD | Male-baised eQTL |
| rs72781202 | chr2:34235605:A:T | - | 0.0805504784209209 | 0.0173746264776388 | LUAD | Male-baised eQTL |
| rs10181363 | chr2:20076649:C:G | - | 0.0947848633761267 | 0.0178586559419955 | LUAD | Male-baised eQTL |
| rs10207631 | chr2:34203775:C:T | - | 0.092533164369821 | 0.0201740528404514 | LUAD | Male-baised eQTL |
| rs10183918 | chr2:34203777:A:C | - | 0.092533164369821 | 0.0201740528404514 | LUAD | Male-baised eQTL |
| rs112422861 | chr2:34204069:G:A | - | 0.092533164369821 | 0.0201740528404514 | LUAD | Male-baised eQTL |
| rs10192770 | chr2:20075661:T:C | - | 0.0919960017532229 | 0.0216726340630874 | LUAD | Male-baised eQTL |
| rs10193138 | chr2:20075970:T:C | - | 0.0919960017532229 | 0.0216726340630874 | LUAD | Male-baised eQTL |
| rs13413192 | chr2:20076136:T:C | - | 0.0914023034645594 | 0.0259276522756839 | LUAD | Male-baised eQTL |
| rs13400037 | chr2:20076318:C:T | - | 0.0914023034645594 | 0.0259276522756839 | LUAD | Male-baised eQTL |
| rs17326929 | chr2:35102105:A:G | - | -0.065324712632787 | 0.0275660340650872 | LUAD | Male-baised eQTL |
| rs13400145 | chr2:20076427:C:T | - | 0.0909048096893904 | 0.0276523434991407 | LUAD | Male-baised eQTL |
| rs2193796 | chr2:34193013:C:T | - | 0.0640802683506489 | 0.0276755769590339 | LUAD | Male-baised eQTL |
| rs10490441 | chr2:34241419:A:G | - | 0.0773596831906317 | 0.0380359033154383 | LUAD | Male-baised eQTL |
| rs11900261 | chr2:22750476:A:G | - | 0.120219955219718 | 0.0407716563951437 | LUAD | Male-baised eQTL |
| rs1466418 | chr2:20075142:C:T | - | 0.0809673510562828 | 0.044481509720528 | LUAD | Male-baised eQTL |
| rs72782903 | chr2:34236101:C:A | - | 0.0768356976537956 | 0.0447600101430086 | LUAD | Male-baised eQTL |
| rs73223845 | chr2:20078287:G:A | - | 0.109722690158416 | 0.0457673568758257 | LUAD | Male-baised eQTL |
| rs17398857 | chr2:35104051:C:A | - | -0.0646550876824088 | 0.0467484608272652 | LUAD | Male-baised eQTL |
| rs7587767 | chr2:34488660:T:G | - | 0.107298754367582 | 0.0470703560464303 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000084731 |
| CpG Site: cg27509510 | |
| Position to Gene: gene | |
| Male Effect: -0.425474897656575 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg27509510 | chr2:25977132 | gene | -0.425474897656575 | 1.43819303368314e-07 | -0.4092009889844183 | 2.0593013088731392e-10 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of KIF3C |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000084731 | KIF3C | C0004238 | Atrial Fibrillation | 2 | CTD_human |
| ENSG00000084731 | KIF3C | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
| ENSG00000084731 | KIF3C | C1862939 | AMYOTROPHIC LATERAL SCLEROSIS 1 | 1 | CTD_human |
| ENSG00000084731 | KIF3C | C1862941 | Amyotrophic Lateral Sclerosis, Sporadic | 1 | CTD_human |
| ENSG00000084731 | KIF3C | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
| ENSG00000084731 | KIF3C | C3468561 | familial atrial fibrillation | 2 | CTD_human |
| ENSG00000084731 | KIF3C | C4551993 | Amyotrophic Lateral Sclerosis, Familial | 1 | CTD_human |
