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Gene: ENSG00000074964 |
Summary for ARHGEF10L |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000074964 | Gene symbol | ARHGEF10L |
| Gene name | Rho guanine nucleotide exchange factor 10 like | |
| HGNC | 25540 | |
| Entrez ID | 55160 | |
| Gene type | protein_coding | |
| Synonyms | ARHGEF10L|FLJ10521|KIAA1626 | |
| UniProtAcc | Q9HCE6 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ARHGEF10L |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ARHGEF10L | 3.82e+03 | -1.68e+00 | 3.12e-01 | -5.39e+00 | 7.17e-08 | 6.71e-07 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for ARHGEF10L |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for ARHGEF10L |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| CHOL | cg10115348 | chr1:17539158 | CGI:chr1:17539434-17540048 | promoter | 7.75e-01 | 6.64e-01 | 2.61e+00 | 9.04e-03 | 2.00e-02 | 1.12e-01 |
| CHOL | cg10123662 | chr1:17539218 | CGI:chr1:17539434-17540048 | promoter | 5.32e-01 | 3.77e-01 | 2.32e+00 | 2.01e-02 | 3.30e-02 | 1.55e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg10115348 | chr1:17539158 | CGI:chr1:17539434-17540048 | promoter | 6.20e-01 | 7.52e-01 | -2.63e+00 | 8.49e-03 | 1.24e-02 | -1.33e-01 |
| ESCA | cg10115348 | chr1:17539158 | CGI:chr1:17539434-17540048 | promoter | 5.89e-01 | 4.00e-01 | 2.15e+00 | 3.12e-02 | 4.42e-02 | 1.89e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRP | cg10115348 | chr1:17539158 | CGI:chr1:17539434-17540048 | promoter | 8.27e-01 | 7.03e-01 | 3.13e+00 | 1.72e-03 | 5.42e-03 | 1.24e-01 |
Top |
Exon skipping events with PSI in TCGA for ARHGEF10L |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| CHOL | exon_skip_2091 | 7.85e-01 | 9.35e-01 | -2.57e+00 | 1.02e-02 | 2.22e-02 | -1.50e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for ARHGEF10L |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for ARHGEF10L |
| TFs related to ARHGEF10L. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ARHGEF10L related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ARHGEF10L |
| RBPs related to ES in ARHGEF10L. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| UVM | BRUNOL4 | exon_skip_2123 | 7.38e+00 | 9.83e-01 | 7.03e+00 | 5.17e-03 | Male-biased |
| UVM | BRUNOL5 | exon_skip_2123 | 7.40e+00 | 9.83e-01 | 7.06e+00 | 5.20e-03 | Male-biased |
| UVM | hnRNPLL | exon_skip_2123 | 7.28e+00 | 9.83e-01 | 6.93e+00 | 5.21e-03 | Male-biased |
| LIHC | SRSF9 | exon_skip_2076 | 6.20e+00 | 1.91e-03 | 6.81e+00 | 9.82e-01 | Female-biased |
| PCPG | IGF2BP1 | exon_skip_2083 | 1.02e+01 | 9.84e-01 | 9.92e+00 | 1.43e-02 | Male-biased |
| MESO | IGF2BP1 | exon_skip_2083 | 9.89e+00 | 5.62e-03 | 1.03e+01 | 9.93e-01 | Female-biased |
| KICH | IGF2BP1 | exon_skip_2083 | 9.82e+00 | 3.15e-03 | 1.02e+01 | 9.95e-01 | Female-biased |
| ARHGEF10L related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6659022 | chr1:22658211:C:T | - | 0.112502404082122 | 0.00847021101574495 | LUAD | Female-baised eQTL |
| rs6603859 | chr1:16379580:G:T | - | -0.0462799820533404 | 0.0111520003982044 | LUAD | Female-baised eQTL |
| rs11260738 | chr1:16374298:G:A | - | -0.0450877078020077 | 0.0163990082463092 | LUAD | Female-baised eQTL |
| rs2977238 | chr1:17231627:G:A | - | 0.0467398647994344 | 0.0229202641577578 | LUAD | Female-baised eQTL |
| rs2977237 | chr1:17231103:G:A | - | 0.0454694383623116 | 0.024901886132702 | LUAD | Female-baised eQTL |
| rs3003409 | chr1:17231342:A:C | - | 0.0447819101930176 | 0.0307466207831863 | LUAD | Female-baised eQTL |
| rs74705609 | chr1:17272972:C:T | - | 0.0846471111256072 | 0.0332431336308799 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs78128878 | chr1:26894134:T:C | - | 0.162394944010392 | 0.0425482643451533 | PAAD | Male-baised eQTL |
| rs113849058 | chr1:26896515:C:T | - | 0.162450700504923 | 0.0427439672064585 | PAAD | Male-baised eQTL |
| rs769897 | chr1:9039668:A:G | - | 0.245926995818369 | 0.00667853859479137 | SARC | Male-baised eQTL |
| rs77855246 | chr1:20493113:C:A | - | 0.177761578260063 | 0.0124278221334943 | SARC | Male-baised eQTL |
| rs113240820 | chr1:26882675:G:T | - | 0.173113508740349 | 0.0206862510785639 | SARC | Male-baised eQTL |
| rs141847393 | chr1:26885718:T:C | - | 0.173113508740349 | 0.0206862510785639 | SARC | Male-baised eQTL |
| rs144171499 | chr1:26869648:G:A | - | 0.164756262026627 | 0.0336166628425704 | SARC | Male-baised eQTL |
| rs139297081 | chr1:26873616:A:G | - | 0.164756262026627 | 0.0336166628425704 | SARC | Male-baised eQTL |
| rs113476222 | chr1:26873629:G:A | - | 0.164756262026627 | 0.0336166628425704 | SARC | Male-baised eQTL |
| rs75584730 | chr1:26875006:G:A | - | 0.164756262026627 | 0.0336166628425704 | SARC | Male-baised eQTL |
| rs76995736 | chr1:26877382:C:A | - | 0.164756262026627 | 0.0336166628425704 | SARC | Male-baised eQTL |
| rs6426681 | chr1:21382342:G:A | - | 0.1431327982848 | 0.0290082894525843 | LGG | Male-baised eQTL |
| rs2270979 | chr1:17696795:C:T | gene | -0.070977598887858 | 0.0119240975195729 | KIRC | Male-baised eQTL |
| rs2270978 | chr1:17696870:C:T | gene,CDS,exon,UTR | -0.070977598887858 | 0.0119240975195729 | KIRC | Male-baised eQTL |
| rs2354290 | chr1:17693366:A:G | gene | -0.0700734974753986 | 0.013104133502659 | KIRC | Male-baised eQTL |
| rs10888050 | chr1:17695994:T:C | gene | -0.0700734974753986 | 0.013104133502659 | KIRC | Male-baised eQTL |
| rs1416853 | chr1:17698385:G:C | - | -0.0690121031652846 | 0.0196234584019182 | KIRC | Male-baised eQTL |
| rs12023874 | chr1:17699117:A:G | - | -0.0692508439236204 | 0.0203169154817582 | KIRC | Male-baised eQTL |
| rs12023877 | chr1:17699138:A:C | - | -0.0692508439236204 | 0.0203169154817582 | KIRC | Male-baised eQTL |
| rs4920620 | chr1:17696659:A:G | gene | -0.0687652982013514 | 0.0227543611243807 | KIRC | Male-baised eQTL |
| rs11203435 | chr1:17683738:T:A | gene | 0.0708148041818497 | 0.0301876418201584 | KIRC | Male-baised eQTL |
| rs12729433 | chr1:17686594:C:G | gene | 0.0700894411757285 | 0.0349964379060506 | KIRC | Male-baised eQTL |
| rs6689540 | chr1:17687325:T:C | gene | 0.0699752018084585 | 0.0359091329330669 | KIRC | Male-baised eQTL |
| rs74061959 | chr1:17689667:G:A | gene | 0.0699752018084585 | 0.0359091329330669 | KIRC | Male-baised eQTL |
| rs72879056 | chr1:26609222:A:G | - | 0.0989977668725596 | 0.0360830977153774 | KIRC | Male-baised eQTL |
| rs2279815 | chr1:17695571:G:T | gene | -0.0652535055502077 | 0.0396781083275502 | KIRC | Male-baised eQTL |
| rs905390 | chr1:17691760:A:C | gene | -0.0682219747817183 | 0.0478609446292865 | KIRC | Male-baised eQTL |
| rs905389 | chr1:17694911:T:C | gene,exon | -0.0636552076163519 | 0.0491981166601735 | KIRC | Male-baised eQTL |
| rs10917288 | chr1:22745352:C:G | - | 0.0719971418878379 | 0.00883349951104876 | BLCA | Male-baised eQTL |
| rs4263970 | chr1:22737437:T:C | - | 0.059705614053598 | 0.0131583482564403 | BLCA | Male-baised eQTL |
| rs4612601 | chr1:22740551:G:A | - | 0.059377005251489 | 0.015324897292624 | BLCA | Male-baised eQTL |
| rs12567471 | chr1:14456462:T:C | - | -0.0633201013396279 | 0.0156516611837671 | BLCA | Male-baised eQTL |
| rs56867169 | chr1:7893471:G:A | - | 0.121405723622368 | 0.0165393696244054 | BLCA | Male-baised eQTL |
| rs6690681 | chr1:14456093:G:T | - | -0.0611471087123062 | 0.021162837208315 | BLCA | Male-baised eQTL |
| rs11121271 | chr1:8933633:C:T | - | 0.054461142313094 | 0.0224130955301497 | BLCA | Male-baised eQTL |
| rs2992758 | chr1:18480011:G:C | - | 0.0729054737369459 | 0.0226743727090737 | BLCA | Male-baised eQTL |
| rs882025 | chr1:22723859:G:A | - | 0.0567103709676824 | 0.0245353724693272 | BLCA | Male-baised eQTL |
| rs1889862 | chr1:18483992:A:C | - | 0.0731536308299384 | 0.0250301782482576 | BLCA | Male-baised eQTL |
| rs882024 | chr1:22723769:T:G | - | 0.0565220405102723 | 0.0274951903952616 | BLCA | Male-baised eQTL |
| rs2904122 | chr1:22733291:T:C | - | 0.0556261122234682 | 0.0330333874571061 | BLCA | Male-baised eQTL |
| rs2869512 | chr1:22733338:T:C | - | 0.0556261122234682 | 0.0330333874571061 | BLCA | Male-baised eQTL |
| rs6662664 | chr1:14451274:A:G | - | -0.0598991530797639 | 0.0341701365702234 | BLCA | Male-baised eQTL |
| rs7530275 | chr1:14457160:G:A | - | -0.0593269559567405 | 0.0375486602169478 | BLCA | Male-baised eQTL |
| rs6691839 | chr1:26232815:G:T | - | -0.0584073318705283 | 0.0398204233649063 | BLCA | Male-baised eQTL |
| rs2486769 | chr1:14459813:T:G | - | -0.0587122754182058 | 0.0410310465837007 | BLCA | Male-baised eQTL |
| rs35066330 | chr1:22814990:G:A | - | -0.0547909495440652 | 0.041614592986689 | BLCA | Male-baised eQTL |
| rs6671980 | chr1:14453163:T:G | - | -0.0587980352007708 | 0.0425529467930874 | BLCA | Male-baised eQTL |
| rs6659078 | chr1:14450236:A:C | - | -0.0581716497317489 | 0.0435052971539657 | BLCA | Male-baised eQTL |
| rs2486768 | chr1:14459350:C:T | - | -0.0580344017228502 | 0.0436009406583397 | BLCA | Male-baised eQTL |
| rs1360920 | chr1:18479204:C:T | - | 0.0669743608571236 | 0.048200106671576 | BLCA | Male-baised eQTL |
| rs17397415 | chr1:14455420:G:A | - | -0.0579697825367483 | 0.0482047685170252 | BLCA | Male-baised eQTL |
| rs4614253 | chr1:14456860:A:T | - | 0.065108981977455 | 0.0456972613949715 | LUAD | Male-baised eQTL |
| rs4655167 | chr1:20250537:G:C | - | -0.095962142413666 | 0.0133527304625469 | COAD | Male-baised eQTL |
| rs2473625 | chr1:14584737:T:C | - | 0.084931427132692 | 0.0135153360380401 | COAD | Male-baised eQTL |
| rs517267 | chr1:14608808:G:T | - | 0.0795463050254868 | 0.0176484026646507 | COAD | Male-baised eQTL |
| rs909948 | chr1:18498709:G:A | - | 0.105524646948644 | 0.0183064288702941 | COAD | Male-baised eQTL |
| rs640109 | chr1:14608830:T:C | - | 0.078274713298682 | 0.0215713091091347 | COAD | Male-baised eQTL |
| rs12025574 | chr1:14595676:G:A | - | -0.0785876778205888 | 0.0227764862009618 | COAD | Male-baised eQTL |
| rs9430635 | chr1:9678728:C:G | - | 0.0604434139807005 | 0.0270480096949101 | COAD | Male-baised eQTL |
| rs9919249 | chr1:18496520:C:A | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs9919202 | chr1:18496628:G:T | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs9919287 | chr1:18496736:T:C | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs28582432 | chr1:18496833:C:A | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs2009682 | chr1:18497468:A:G | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs9919318 | chr1:18498112:T:G | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs9919236 | chr1:18498317:G:T | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs12385722 | chr1:18498890:T:C | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs11261024 | chr1:18499307:G:A | - | 0.105175430175624 | 0.0297366036089391 | COAD | Male-baised eQTL |
| rs11261025 | chr1:18500216:A:G | - | 0.104923597108805 | 0.0304309860566898 | COAD | Male-baised eQTL |
| rs12116479 | chr1:14591407:G:C | - | -0.0805524073644655 | 0.0313754023472346 | COAD | Male-baised eQTL |
| rs12074637 | chr1:18493293:A:T | - | 0.111016251316139 | 0.0334437053370733 | COAD | Male-baised eQTL |
| rs58026570 | chr1:18494000:A:T | - | 0.111016251316139 | 0.0334437053370733 | COAD | Male-baised eQTL |
| rs6676514 | chr1:14600949:A:G | - | 0.0724436969701271 | 0.0354162045521278 | COAD | Male-baised eQTL |
| rs2185151 | chr1:24743448:G:A | - | -0.0619948849731098 | 0.0398390461560388 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000074964 |
| CpG Site: cg21645973 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.370281835320747 | |
| Female Effect: - | |
 | Gene ID: ENSG00000074964 |
| CpG Site: cg06980341 | |
| Position to Gene: gene | |
| Male Effect: -0.400059075814293 | |
| Female Effect: - | |
 | Gene ID: ENSG00000074964 |
| CpG Site: cg25979543 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.259306819452194 | |
 | Gene ID: ENSG00000074964 |
| CpG Site: cg06980341 | |
| Position to Gene: gene | |
| Male Effect: -0.188948322381275 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg21645973 | chr1:17587575 | gene,exon,CDS | -0.370281835320747 | 1.79700257055504e-07 | -0.5770991363375222 | 4.973204766760202e-10 | PAAD |
| cg06980341 | chr1:17548107 | gene | -0.400059075814293 | 7.53520807602135e-09 | -0.45691691528040157 | 9.230989656658904e-12 | KIRP |
| cg06980341 | chr1:17548107 | gene | -0.188948322381275 | 2.82410550600799e-05 | -0.33318952122339773 | 2.426142248775448e-09 | BLCA |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg25979543 | chr1:17561609 | gene | -0.259306819452194 | 1.08792570586928e-05 | -0.3475420351424209 | 1.189378957908425e-08 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs11261095 | chr1:18148067:C:A | Distant downstream | -0.106598269809885 | 0.0412597640339755 | KIRC | Female-baised sQTL |
| exon_skip_2106 | chr1:17648553:17648675 | Frame-shift | rs11579504 | chr1:17306751:A:G | Distant upstream | -0.0199284314880093 | 0.049538574686242 | LUAD | Female-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs708090 | chr1:17833038:C:A | Distant downstream | 0.121468028289973 | 0.0323527501688841 | BLCA | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_2106 | chr1:17648553:17648675 | Frame-shift | rs4920483 | chr1:18355438:T:C | Distant downstream | 0.0213047000703611 | 0.0295649145585756 | LUAD | Male-baised sQTL |
| exon_skip_2075 | chr1:17613057:17613174 | In-frame | rs10788679 | chr1:17590467:A:G | Distant upstream | -0.0252683073113536 | 0.00249502754377808 | LGG | Male-baised sQTL |
| exon_skip_2075 | chr1:17613057:17613174 | In-frame | rs10788678 | chr1:17590424:T:A | Distant upstream | -0.0239030203930668 | 0.00293576024907881 | LGG | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs4920476 | chr1:18316855:C:T | Distant downstream | 0.0675888084350798 | 0.00373691545518312 | COAD | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs223211 | chr1:18318978:A:G | Distant downstream | 0.0751240692332549 | 0.00687524948776823 | COAD | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs11260982 | chr1:18318233:G:C | Distant downstream | 0.0638654200755037 | 0.0221746912226327 | COAD | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs72655178 | chr1:18311074:C:T | Distant downstream | -0.0655119422636968 | 0.0241201031939044 | COAD | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs4920630 | chr1:17747847:C:A | Distant downstream | -0.039445608184889 | 0.0247358561704933 | COAD | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs708083 | chr1:18310766:T:G | Distant downstream | 0.0649936790665876 | 0.0435590685467332 | COAD | Male-baised sQTL |
| exon_skip_2091 | chr1:17634547:17634562 | In-frame | rs4920475 | chr1:18316841:C:T | Distant downstream | 0.0581360316016598 | 0.0483182073012826 | COAD | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of ARHGEF10L |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
