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Gene: ENSG00000074855 |
Summary for ANO8 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000074855 | Gene symbol | ANO8 |
| Gene name | anoctamin 8 | |
| HGNC | 29329 | |
| Entrez ID | 57719 | |
| Gene type | protein_coding | |
| Synonyms | ANO8| | |
| UniProtAcc | Q9HCE9 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ANO8 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ANO8 | 6.63e+02 | -1.03e+00 | 1.48e-01 | -6.99e+00 | 2.82e-12 | 2.31e-11 | HNSC |
| ANO8 | 9.22e+02 | 1.50e+00 | 3.22e-01 | 4.68e+00 | 2.92e-06 | 2.01e-05 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for ANO8 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for ANO8 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| ACC | cg00363845 | chr19:17335328 | CGI:chr19:17334263-17334998 | promoter | 3.37e-01 | 4.97e-01 | -2.57e+00 | 1.02e-02 | 2.57e-02 | -1.60e-01 |
| ACC | cg03665970 | chr19:17335295 | CGI:chr19:17334263-17334998 | promoter | 3.92e-01 | 5.27e-01 | -2.09e+00 | 3.68e-02 | 4.46e-02 | -1.35e-01 |
| KICH | cg00363845 | chr19:17335328 | CGI:chr19:17334263-17334998 | promoter | 5.35e-01 | 3.93e-01 | 2.13e+00 | 3.32e-02 | 4.41e-02 | 1.42e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| CHOL | cg23324101 | chr19:17333590 | CGI:chr19:17333156-17333824 | promoter,exon,gene body | 8.48e-01 | 9.84e-01 | -2.36e+00 | 1.83e-02 | 2.92e-02 | -1.36e-01 |
| CHOL | cg20042338 | chr19:17333612 | CGI:chr19:17333156-17333824 | promoter,exon,gene body | 8.52e-01 | 9.88e-01 | -1.99e+00 | 4.65e-02 | 4.65e-02 | -1.35e-01 |
| CHOL | cg00363845 | chr19:17335328 | CGI:chr19:17334263-17334998 | promoter | 4.40e-01 | 5.65e-01 | -1.99e+00 | 4.65e-02 | 4.65e-02 | -1.25e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for ANO8 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_316313 | 9.81e-01 | 8.71e-01 | 7.14e+00 | 9.66e-13 | 1.06e-11 | 1.09e-01 |
Top |
RNA A-to-I editing events in TCGA for ANO8 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for ANO8 |
| TFs related to ANO8. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | PLAGL2 | ANO8 | 3.68e+00 | 1.15e-02 | 4.86e+00 | 9.83e-01 | Female-biased |
| MESO | FOXR2 | ANO8 | 2.58e+00 | 4.28e-03 | 4.10e+00 | 9.83e-01 | Female-biased |
| MESO | ZNF418 | ANO8 | 2.43e+00 | 3.98e-04 | 4.58e+00 | 9.93e-01 | Female-biased |
| MESO | ZNF570 | ANO8 | 2.65e+00 | 5.06e-03 | 4.11e+00 | 9.82e-01 | Female-biased |
| MESO | ZNF79 | ANO8 | 2.64e+00 | 1.85e-03 | 4.40e+00 | 9.90e-01 | Female-biased |
| ANO8 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ANO8 |
| RBPs related to ES in ANO8. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | ZC3H10 | exon_skip_316302 | 9.25e+00 | 1.15e-03 | 1.06e+01 | 9.98e-01 | Female-biased |
| ESCA | ZC3H10 | exon_skip_316302 | 9.91e+00 | 9.84e-01 | 9.51e+00 | 1.38e-02 | Male-biased |
| ANO8 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000074855 | LINC01355,hsa-mir-203a,ANO8 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000074855 | AL121832.1,hsa-mir-203a,ANO8 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000074855 | LINC01409,hsa-mir-203a,ANO8 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000074855 | UCA1,hsa-mir-203a,ANO8 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000074855 | LINC01342,hsa-mir-32,ANO8 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000074855 | AC087741.1,hsa-mir-32,ANO8 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000074855 | AL022322.1,hsa-mir-32,ANO8 | Male-specific ceRNA | TCGA-BLCA |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2188972 | chr19:21966656:A:G | - | -0.0611590036049862 | 0.0341861349756809 | LUAD | Female-baised eQTL |
| rs12608935 | chr19:21962345:T:C | - | -0.058790561533694 | 0.0471817981504619 | LUAD | Female-baised eQTL |
| rs1849005 | chr19:21959941:T:C | - | -0.0589013357699269 | 0.0472482645228922 | LUAD | Female-baised eQTL |
| rs2666455 | chr19:21944733:T:G | - | -0.0586794241211331 | 0.0479815805766046 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs67646933 | chr19:19693882:T:G | - | 0.119005780910803 | 0.0092280259035188 | LUAD | Male-baised eQTL |
| rs112571202 | chr19:19694929:T:C | - | 0.119005780910803 | 0.0092280259035188 | LUAD | Male-baised eQTL |
| rs8110982 | chr19:19732447:C:T | - | 0.122749208709346 | 0.00955227661552796 | LUAD | Male-baised eQTL |
| rs11086073 | chr19:17498587:T:C | - | -0.0783724814161768 | 0.0230773640786924 | LUAD | Male-baised eQTL |
| rs1820805 | chr19:17499401:G:A | - | -0.0734261248860369 | 0.0472703416168926 | LUAD | Male-baised eQTL |
| rs12720218 | chr19:10380212:G:A | - | 0.0841633892118203 | 0.0491455562390237 | LUAD | Male-baised eQTL |
| rs11879844 | chr19:17195988:A:G | - | 0.0876248906686365 | 0.00218897412331936 | COAD | Male-baised eQTL |
| rs11882299 | chr19:17195851:G:A | - | 0.0883029640499474 | 0.00424428815833678 | COAD | Male-baised eQTL |
| rs10420397 | chr19:20331022:C:A | - | 0.0677928557091533 | 0.00532781638883247 | COAD | Male-baised eQTL |
| rs11879528 | chr19:20333451:C:T | - | 0.0677928557091533 | 0.00532781638883247 | COAD | Male-baised eQTL |
| rs12608524 | chr19:8487283:C:T | - | -0.0831836114851826 | 0.00811292580053507 | COAD | Male-baised eQTL |
| rs10423457 | chr19:22096465:G:C | - | 0.0482669028669989 | 0.011127053717476 | COAD | Male-baised eQTL |
| rs6511328 | chr19:22104177:G:A | - | 0.0482669028669989 | 0.011127053717476 | COAD | Male-baised eQTL |
| rs62111040 | chr19:22104709:G:A | - | 0.0482669028669989 | 0.011127053717476 | COAD | Male-baised eQTL |
| rs1968446 | chr19:22096245:A:C | - | 0.0480740613168857 | 0.0118512765812953 | COAD | Male-baised eQTL |
| rs7256462 | chr19:22099191:T:C | - | 0.0480740613168857 | 0.0118512765812953 | COAD | Male-baised eQTL |
| rs10425828 | chr19:22100275:A:G | - | 0.0480740613168857 | 0.0118512765812953 | COAD | Male-baised eQTL |
| rs8106762 | chr19:22101934:C:T | - | 0.0480740613168857 | 0.0118512765812953 | COAD | Male-baised eQTL |
| rs2359833 | chr19:22059419:T:G | - | 0.0470298736327263 | 0.0123225856908493 | COAD | Male-baised eQTL |
| rs7247147 | chr19:22067056:G:C | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs7247228 | chr19:22067334:C:T | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs7248305 | chr19:22067469:T:A | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs7250852 | chr19:22067708:G:A | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs7251660 | chr19:22067812:T:C | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs7250905 | chr19:22067941:C:T | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs2043317 | chr19:22068294:T:C | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs2043316 | chr19:22068402:C:T | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs8108651 | chr19:22068662:A:G | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10420019 | chr19:22069103:T:A | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10419142 | chr19:22069460:A:T | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10420898 | chr19:22069529:T:C | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10419184 | chr19:22069540:A:G | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10401922 | chr19:22070450:T:A | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10422289 | chr19:22073258:C:T | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10411275 | chr19:22076667:A:G | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs10411943 | chr19:22076980:A:G | - | 0.0469060926188443 | 0.0127298032456384 | COAD | Male-baised eQTL |
| rs62110990 | chr19:22077639:G:T | - | 0.0469807593106042 | 0.012807681555161 | COAD | Male-baised eQTL |
| rs6511314 | chr19:22053593:C:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs6511315 | chr19:22053701:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7259971 | chr19:22054517:C:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs6511316 | chr19:22054827:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10406553 | chr19:22054999:G:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10406653 | chr19:22055221:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10407250 | chr19:22055349:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10412953 | chr19:22055680:C:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs8110841 | chr19:22056634:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs8110047 | chr19:22056700:A:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs4510150 | chr19:22056867:A:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs4542784 | chr19:22056949:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs4257328 | chr19:22057288:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10404669 | chr19:22058416:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs9973249 | chr19:22059358:T:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs2163837 | chr19:22059434:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs2163836 | chr19:22059475:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs2163835 | chr19:22059877:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs28857211 | chr19:22060302:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs28894669 | chr19:22060462:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10423881 | chr19:22060620:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10423522 | chr19:22060646:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10406551 | chr19:22061718:T:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10405613 | chr19:22061970:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10405673 | chr19:22062088:A:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10406485 | chr19:22062200:G:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10406119 | chr19:22062207:C:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs28822164 | chr19:22062306:C:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10408150 | chr19:22062423:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7249591 | chr19:22062543:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7251884 | chr19:22062728:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7252023 | chr19:22062844:C:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7253053 | chr19:22062883:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7252550 | chr19:22063215:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10413784 | chr19:22063389:A:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10407173 | chr19:22063861:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs8104144 | chr19:22064111:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs8103518 | chr19:22064150:G:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs8104630 | chr19:22064475:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10414685 | chr19:22064947:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10414861 | chr19:22064959:C:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10415930 | chr19:22065286:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10417285 | chr19:22065382:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10415794 | chr19:22065419:C:T | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10423114 | chr19:22066487:A:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs9653157 | chr19:22066688:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs9653142 | chr19:22066794:A:G | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs7247041 | chr19:22066988:G:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs10420042 | chr19:22069124:T:A | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs2043315 | chr19:22070021:T:C | - | 0.0463079019623811 | 0.014513758033249 | COAD | Male-baised eQTL |
| rs8108976 | chr19:22068899:C:A | - | 0.0461881741361148 | 0.0155239116481693 | COAD | Male-baised eQTL |
| rs8100768 | chr19:22087666:T:C | - | 0.0476462524820773 | 0.0158862830700894 | COAD | Male-baised eQTL |
| rs10418804 | chr19:22090213:T:C | - | 0.0476462524820773 | 0.0158862830700894 | COAD | Male-baised eQTL |
| rs10424447 | chr19:22091240:A:G | - | 0.0476462524820773 | 0.0158862830700894 | COAD | Male-baised eQTL |
| rs2043319 | chr19:22091793:A:G | - | 0.0476462524820773 | 0.0158862830700894 | COAD | Male-baised eQTL |
| rs28374572 | chr19:22093676:A:C | - | 0.0476462524820773 | 0.0158862830700894 | COAD | Male-baised eQTL |
| rs10417916 | chr19:22089813:T:C | - | 0.0474497251369663 | 0.0168534671758165 | COAD | Male-baised eQTL |
| rs28547927 | chr19:22094335:G:A | - | 0.0474497251369663 | 0.0168534671758165 | COAD | Male-baised eQTL |
| rs1397579 | chr19:21794162:T:C | - | 0.0517556949390831 | 0.0169564700852193 | COAD | Male-baised eQTL |
| rs28635943 | chr19:22085910:G:T | - | 0.0463440641861586 | 0.0172095612069903 | COAD | Male-baised eQTL |
| rs10426159 | chr19:22084522:G:A | - | 0.0461490692570516 | 0.0182469912629639 | COAD | Male-baised eQTL |
| rs28600030 | chr19:22085641:G:A | - | 0.0461490692570516 | 0.0182469912629639 | COAD | Male-baised eQTL |
| rs6511321 | chr19:22087266:A:G | - | 0.0468172200832525 | 0.0188662038439615 | COAD | Male-baised eQTL |
| rs7259807 | chr19:22108674:A:G | - | 0.045273134358537 | 0.0197083301007537 | COAD | Male-baised eQTL |
| rs10401167 | chr19:22109140:G:A | - | 0.045273134358537 | 0.0197083301007537 | COAD | Male-baised eQTL |
| rs8111854 | chr19:22057411:T:C | - | 0.0448822822766716 | 0.020452211723637 | COAD | Male-baised eQTL |
| rs8110969 | chr19:22057420:C:T | - | 0.0449012793596124 | 0.0239428054595081 | COAD | Male-baised eQTL |
| rs11260002 | chr19:7358071:A:G | - | -0.0567989691209042 | 0.0269382230760262 | COAD | Male-baised eQTL |
| rs11260003 | chr19:7358100:G:A | - | -0.0567989691209042 | 0.0269382230760262 | COAD | Male-baised eQTL |
| rs6511294 | chr19:21795767:G:A | - | -0.0470628876296842 | 0.0278702952170356 | COAD | Male-baised eQTL |
| rs59765317 | chr19:16244627:G:A | - | 0.0599478373754925 | 0.0305385259900888 | COAD | Male-baised eQTL |
| rs113509810 | chr19:21770230:C:T | - | 0.0670547647864799 | 0.0307610495660288 | COAD | Male-baised eQTL |
| rs10796331 | chr19:7358647:G:T | - | -0.0558283682326924 | 0.0338859071969409 | COAD | Male-baised eQTL |
| rs11879985 | chr19:7355337:G:A | - | 0.0546901078178547 | 0.0384801799294805 | COAD | Male-baised eQTL |
| rs62122669 | chr19:21217106:A:G | - | -0.0382621210566572 | 0.0463810142952848 | COAD | Male-baised eQTL |
| rs73014137 | chr19:21217326:T:G | - | -0.0382621210566572 | 0.0463810142952848 | COAD | Male-baised eQTL |
| rs2022515 | chr19:21219835:C:T | - | -0.0382621210566572 | 0.0463810142952848 | COAD | Male-baised eQTL |
| rs202073403 | chr19:16243445:T:G | - | 0.0575703126774778 | 0.0470118620512236 | COAD | Male-baised eQTL |
| rs388637 | chr19:16245720:G:A | - | 0.0575703126774778 | 0.0470118620512236 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000074855 |
| CpG Site: cg12072608 | |
| Position to Gene: gene | |
| Male Effect: -0.391834849681686 | |
| Female Effect: - | |
 | Gene ID: ENSG00000074855 |
| CpG Site: cg23408253 | |
| Position to Gene: gene | |
| Male Effect: -0.254866384209361 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg12072608 | chr19:17326611 | gene | -0.391834849681686 | 5.45236731246017e-12 | -0.49531876440512623 | 3.820586550789104e-15 | LUAD |
| cg23408253 | chr19:17327946 | gene | -0.254866384209361 | 5.7219769535377e-07 | -0.39042381304048346 | 1.5518322969490755e-09 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_316302 | chr19:17327437:17327569 | In-frame | rs7252308 | chr19:17677980:G:A | Distant upstream | -0.052356853603198 | 0.00612664215172448 | THCA | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of ANO8 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
