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Gene: ENSG00000068903 |
Summary for SIRT2 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000068903 | Gene symbol | SIRT2 |
| Gene name | sirtuin 2 | |
| HGNC | 10886 | |
| Entrez ID | 22933 | |
| Gene type | protein_coding | |
| Synonyms | SIRT2| | |
| UniProtAcc | Q8IXJ6 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000068903 | SIRT2 | DB15493 | Cambinol | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SIRT2 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SIRT2 | 3.25e+03 | -1.09e+00 | 1.12e-01 | -9.72e+00 | 2.58e-22 | 6.94e-21 | HNSC |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for SIRT2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SIRT2 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for SIRT2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BLCA | exon_skip_318322 | 2.01e-01 | 3.42e-01 | -2.90e+00 | 3.72e-03 | 1.22e-02 | -1.41e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| READ | exon_skip_318322 | 1.49e-01 | 3.30e-01 | -4.09e+00 | 4.25e-05 | 3.07e-03 | -1.80e-01 |
Top |
RNA A-to-I editing events in TCGA for SIRT2 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LGG | SIRT2-014 | chr19_38897553_- | 2.00e-01 | 3.01e-01 | -2.12e+00 | 3.39e-02 | 4.78e-02 | -1.00e-01 |
| THCA | SIRT2-014 | chr19_38897621_- | 4.10e-01 | 2.50e-01 | 2.57e+00 | 1.01e-02 | 4.84e-02 | 1.60e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for SIRT2 |
| TFs related to SIRT2. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SIRT2 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SIRT2 |
| RBPs related to ES in SIRT2. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | PCBP2 | exon_skip_318322 | 8.42e+00 | 9.81e-01 | 8.10e+00 | 1.27e-02 | Male-biased |
| ACC | HNRNPH2 | exon_skip_318295 | 7.87e+00 | 6.23e-03 | 8.34e+00 | 9.86e-01 | Female-biased |
| UVM | FXR2 | exon_skip_318300 | 7.35e+00 | 3.99e-03 | 7.73e+00 | 9.86e-01 | Female-biased |
| UVM | HNRNPH2 | exon_skip_318289 | 7.74e+00 | 7.47e-04 | 8.28e+00 | 9.92e-01 | Female-biased |
| THYM | SAMD4A | exon_skip_318300 | 6.57e+00 | 9.80e-01 | 6.11e+00 | 2.30e-03 | Male-biased |
| CHOL | HNRNPH2 | exon_skip_318295 | 8.35e+00 | 9.80e-01 | 7.97e+00 | 1.26e-02 | Male-biased |
| BRCA | ESRP2 | exon_skip_318284 | 6.31e+00 | 4.25e-03 | 7.19e+00 | 9.83e-01 | Female-biased |
| THCA | FXR2 | exon_skip_318300 | 8.00e+00 | 9.83e-01 | 7.69e+00 | 8.11e-03 | Male-biased |
| THCA | HNRNPH2 | exon_skip_318289 | 8.31e+00 | 9.91e-01 | 7.88e+00 | 1.64e-03 | Male-biased |
| PCPG | HNRNPH2 | exon_skip_318289 | 7.97e+00 | 6.43e-03 | 8.32e+00 | 9.86e-01 | Female-biased |
| PCPG | PCBP2 | exon_skip_318322 | 8.56e+00 | 9.92e-01 | 8.10e+00 | 1.98e-03 | Male-biased |
| LGG | SAMD4A | exon_skip_318300 | 6.44e+00 | 2.33e-03 | 6.92e+00 | 9.83e-01 | Female-biased |
| PAAD | SAMD4A | exon_skip_318300 | 6.78e+00 | 9.84e-01 | 6.20e+00 | 3.52e-04 | Male-biased |
| KIRC | HNRNPH2 | exon_skip_318295 | 8.64e+00 | 9.93e-01 | 8.16e+00 | 1.23e-03 | Male-biased |
| BLCA | HNRNPH2 | exon_skip_318289 | 8.29e+00 | 9.86e-01 | 7.89e+00 | 6.79e-03 | Male-biased |
| BLCA | HNRNPH2 | exon_skip_318295 | 8.77e+00 | 9.90e-01 | 8.31e+00 | 4.30e-03 | Male-biased |
| SKCM | HNRNPH2 | exon_skip_318289 | 7.85e+00 | 4.05e-03 | 8.30e+00 | 9.89e-01 | Female-biased |
| HNSC | HNRNPH2 | exon_skip_318289 | 8.03e+00 | 9.87e-01 | 7.60e+00 | 4.41e-03 | Male-biased |
| HNSC | PCBP2 | exon_skip_318322 | 8.67e+00 | 9.90e-01 | 8.23e+00 | 4.23e-03 | Male-biased |
| HNSC | SAMD4A | exon_skip_318300 | 6.07e+00 | 1.60e-04 | 6.81e+00 | 9.85e-01 | Female-biased |
| SARC | SAMD4A | exon_skip_318300 | 6.43e+00 | 1.93e-03 | 6.97e+00 | 9.84e-01 | Female-biased |
| SIRT2 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs4427917 | chr19:47312458:G:C | - | 0.0975666087350309 | 0.0469668264598086 | LUSC | Female-baised eQTL |
| rs11668733 | chr19:47311899:T:C | - | 0.0982948752017281 | 0.0470292711161877 | LUSC | Female-baised eQTL |
| rs11668768 | chr19:47311935:T:C | - | 0.0982948752017281 | 0.0470292711161877 | LUSC | Female-baised eQTL |
| rs7258597 | chr19:37905755:A:G | - | 0.112573224389058 | 0.0375644188828484 | BLCA | Female-baised eQTL |
| rs7250409 | chr19:37928238:C:T | - | 0.112573224389058 | 0.0375644188828484 | BLCA | Female-baised eQTL |
| rs9304572 | chr19:37929966:C:T | - | 0.112573224389058 | 0.0375644188828484 | BLCA | Female-baised eQTL |
| rs705494 | chr19:37935396:G:A | - | 0.112573224389058 | 0.0375644188828484 | BLCA | Female-baised eQTL |
| rs833926 | chr19:37942796:A:G | - | 0.112573224389058 | 0.0375644188828484 | BLCA | Female-baised eQTL |
| rs8107341 | chr19:37944920:C:T | - | 0.112573224389058 | 0.0375644188828484 | BLCA | Female-baised eQTL |
| rs10404567 | chr19:37906573:A:G | - | 0.112957754713639 | 0.0448037920284106 | BLCA | Female-baised eQTL |
| rs8110284 | chr19:37931877:C:T | - | 0.112957754713639 | 0.0448037920284106 | BLCA | Female-baised eQTL |
| rs705492 | chr19:37947898:T:G | - | 0.112957754713639 | 0.0448037920284106 | BLCA | Female-baised eQTL |
| rs1618385 | chr19:38052254:C:T | - | 0.0367516547439434 | 0.0203171910483107 | LUAD | Female-baised eQTL |
| rs1620082 | chr19:38051363:A:T | - | 0.0365162175614989 | 0.0215721160946504 | LUAD | Female-baised eQTL |
| rs7249241 | chr19:38052822:T:C | - | 0.0363002761345193 | 0.0241574377068887 | LUAD | Female-baised eQTL |
| rs941036 | chr19:38052855:T:C | - | 0.0363002761345193 | 0.0241574377068887 | LUAD | Female-baised eQTL |
| rs941037 | chr19:38052986:C:T | - | 0.0363002761345193 | 0.0241574377068887 | LUAD | Female-baised eQTL |
| rs1725464 | chr19:38051627:A:C | - | 0.0355656980357814 | 0.0292561746821129 | LUAD | Female-baised eQTL |
| rs1654342 | chr19:38052437:G:C | - | 0.0357299984148843 | 0.0293383664141669 | LUAD | Female-baised eQTL |
| rs1616705 | chr19:38050953:A:G | - | 0.0354143183741943 | 0.0298764689759448 | LUAD | Female-baised eQTL |
| rs1725463 | chr19:38051050:T:C | - | 0.0354143183741943 | 0.0298764689759448 | LUAD | Female-baised eQTL |
| rs1725467 | chr19:38053263:A:C | - | 0.0354661355005782 | 0.0300072759160516 | LUAD | Female-baised eQTL |
| rs734204 | chr19:38049348:A:G | - | 0.0348759407319898 | 0.0344790834513518 | LUAD | Female-baised eQTL |
| rs1725460 | chr19:38049772:T:C | - | 0.0348759407319898 | 0.0344790834513518 | LUAD | Female-baised eQTL |
| rs1628394 | chr19:38044368:G:C | - | 0.0346286033865793 | 0.0396808666083478 | LUAD | Female-baised eQTL |
| rs7256656 | chr19:38045425:T:C | - | 0.0340731087762493 | 0.0458806224130458 | LUAD | Female-baised eQTL |
| rs1654338 | chr19:38045713:G:T | - | 0.0340731087762493 | 0.0458806224130458 | LUAD | Female-baised eQTL |
| rs6508759 | chr19:38046585:A:G | - | 0.0340731087762493 | 0.0458806224130458 | LUAD | Female-baised eQTL |
| rs1725518 | chr19:38043395:C:A | - | 0.0338172310563648 | 0.0491062068840499 | LUAD | Female-baised eQTL |
| rs7251231 | chr19:46031146:G:A | - | -0.0565346313754555 | 0.0452724207537246 | COAD | Female-baised eQTL |
| rs12459710 | chr19:46030629:C:T | - | -0.0558773216045384 | 0.0474729281210324 | COAD | Female-baised eQTL |
| rs12459743 | chr19:46030656:G:A | - | -0.0558773216045384 | 0.0474729281210324 | COAD | Female-baised eQTL |
| rs12983307 | chr19:46030738:T:C | - | -0.0558773216045384 | 0.0474729281210324 | COAD | Female-baised eQTL |
| rs7251398 | chr19:46031306:G:A | - | -0.0558773216045384 | 0.0474729281210324 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1057745 | chr19:39397750:G:C | - | 0.0651673845063992 | 0.00209631754674677 | BLCA | Male-baised eQTL |
| rs78962501 | chr19:38487359:T:G | - | 0.0545401145754581 | 0.0418301350756434 | BLCA | Male-baised eQTL |
| rs74778515 | chr19:38489101:G:A | - | 0.0525075299989645 | 0.0422574619480619 | BLCA | Male-baised eQTL |
| rs17708009 | chr19:38490363:C:T | - | 0.05405983849221 | 0.0427294319263398 | BLCA | Male-baised eQTL |
| rs10411556 | chr19:46321647:T:A | - | -0.0499991505641104 | 0.0271442739437121 | LUAD | Male-baised eQTL |
| rs2902474 | chr19:34643895:A:G | - | 0.128815900479902 | 0.00623792115728415 | COAD | Male-baised eQTL |
| rs12979040 | chr19:36190516:C:T | - | -0.138805998777332 | 0.0145220340236966 | COAD | Male-baised eQTL |
| rs138059943 | chr19:36196081:T:C | - | -0.135669958048404 | 0.0158925894455821 | COAD | Male-baised eQTL |
| rs71354126 | chr19:36197144:C:T | - | -0.135393250870506 | 0.0161057228481573 | COAD | Male-baised eQTL |
| rs35669779 | chr19:36375962:A:C | - | -0.141887683796847 | 0.0161337185301318 | COAD | Male-baised eQTL |
| rs76650440 | chr19:36189048:T:C | - | -0.135310990616278 | 0.016332351269544 | COAD | Male-baised eQTL |
| rs12981535 | chr19:36423465:C:A | - | -0.137503622666597 | 0.0190590290689669 | COAD | Male-baised eQTL |
| rs855615 | chr19:38129761:G:A | - | -0.110525178186032 | 0.0215946078992727 | COAD | Male-baised eQTL |
| rs34579456 | chr19:36181794:G:A | - | -0.133508699920396 | 0.0222689923906979 | COAD | Male-baised eQTL |
| rs56316636 | chr19:39775488:T:A | - | -0.0773869217202024 | 0.0229181045639523 | COAD | Male-baised eQTL |
| rs117239556 | chr19:36184289:C:T | - | -0.132975036826406 | 0.0232799127776107 | COAD | Male-baised eQTL |
| rs12979812 | chr19:36185536:G:A | - | -0.132975036826406 | 0.0232799127776107 | COAD | Male-baised eQTL |
| rs1053686 | chr19:39870288:G:A | - | -0.0715848720743224 | 0.0242176923611315 | COAD | Male-baised eQTL |
| rs35927732 | chr19:36174402:C:T | - | -0.136485757651798 | 0.024582968024674 | COAD | Male-baised eQTL |
| rs8108486 | chr19:48141972:G:T | - | 0.0564906417465176 | 0.0253481419667374 | COAD | Male-baised eQTL |
| rs12975337 | chr19:36389185:G:A | - | -0.130537568998827 | 0.0278558487986761 | COAD | Male-baised eQTL |
| rs80099126 | chr19:36389851:C:G | - | -0.130537568998827 | 0.0278558487986761 | COAD | Male-baised eQTL |
| rs146645048 | chr19:36396463:C:T | - | -0.130537568998827 | 0.0278558487986761 | COAD | Male-baised eQTL |
| rs35186959 | chr19:36411718:A:G | - | -0.130537568998827 | 0.0278558487986761 | COAD | Male-baised eQTL |
| rs156644 | chr19:48123681:G:A | - | 0.0645523558868612 | 0.0289937104139145 | COAD | Male-baised eQTL |
| rs71354195 | chr19:36385416:G:C | - | -0.12994990944961 | 0.0292918135823273 | COAD | Male-baised eQTL |
| rs35778194 | chr19:36395912:T:C | - | -0.12994990944961 | 0.0292918135823273 | COAD | Male-baised eQTL |
| rs35951452 | chr19:36402253:G:C | - | -0.12994990944961 | 0.0292918135823273 | COAD | Male-baised eQTL |
| rs7256914 | chr19:36406187:T:C | - | -0.12994990944961 | 0.0292918135823273 | COAD | Male-baised eQTL |
| rs12979121 | chr19:36414054:C:T | - | -0.12994990944961 | 0.0292918135823273 | COAD | Male-baised eQTL |
| rs6508953 | chr19:40896674:A:G | - | 0.0603229031172775 | 0.0329859011208779 | COAD | Male-baised eQTL |
| rs73019629 | chr19:30219648:T:A | - | -0.0849315835667121 | 0.0333673617927712 | COAD | Male-baised eQTL |
| rs419664 | chr19:48137368:A:C | - | 0.0538873019470889 | 0.0371996376813931 | COAD | Male-baised eQTL |
| rs8108407 | chr19:48142077:C:G | - | 0.0538873019470889 | 0.0371996376813931 | COAD | Male-baised eQTL |
| rs1908770 | chr19:31396593:C:A | - | 0.0546363092445794 | 0.0373314800310278 | COAD | Male-baised eQTL |
| rs251699 | chr19:48126761:T:G | - | 0.0627944650210205 | 0.0383730090921513 | COAD | Male-baised eQTL |
| rs187999 | chr19:48136464:A:G | - | 0.053798290155795 | 0.039125602076081 | COAD | Male-baised eQTL |
| rs274897 | chr19:48146026:C:G | - | 0.0539718037538361 | 0.0394431700231486 | COAD | Male-baised eQTL |
| rs156648 | chr19:48118290:G:A | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs251690 | chr19:48121469:G:A | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs153021 | chr19:48124678:T:C | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs156641 | chr19:48128151:C:T | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs2241721 | chr19:48130907:T:C | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs3730986 | chr19:48132723:G:A | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs2288883 | chr19:48133277:T:G | - | 0.0624817634507429 | 0.0395712953320543 | COAD | Male-baised eQTL |
| rs3730989 | chr19:48132653:C:T | - | 0.0624521410843058 | 0.0403584394435762 | COAD | Male-baised eQTL |
| rs251692 | chr19:48115454:A:G | - | 0.0537768250187659 | 0.0403604546273217 | COAD | Male-baised eQTL |
| rs251691 | chr19:48116303:A:G | - | 0.0537768250187659 | 0.0403604546273217 | COAD | Male-baised eQTL |
| rs1616983 | chr19:48111898:T:G | - | 0.0537651080004209 | 0.0404315566672079 | COAD | Male-baised eQTL |
| rs1616981 | chr19:48111899:T:C | - | 0.0537651080004209 | 0.0404315566672079 | COAD | Male-baised eQTL |
| rs20581 | chr19:48119170:A:G | - | 0.0537247515556235 | 0.0407027048898538 | COAD | Male-baised eQTL |
| rs156634 | chr19:48119688:A:G | - | 0.0537247515556235 | 0.0407027048898538 | COAD | Male-baised eQTL |
| rs156633 | chr19:48124005:G:A | - | 0.0537247515556235 | 0.0407027048898538 | COAD | Male-baised eQTL |
| rs156639 | chr19:48128580:G:A | - | 0.0537247515556235 | 0.0407027048898538 | COAD | Male-baised eQTL |
| rs175627 | chr19:48131411:A:G | - | 0.0536518937256841 | 0.041189343198895 | COAD | Male-baised eQTL |
| rs156645 | chr19:48121955:G:A | - | 0.0633253740710335 | 0.0416661811075748 | COAD | Male-baised eQTL |
| rs3730990 | chr19:48131703:T:C | - | 0.061637050167272 | 0.044414624046665 | COAD | Male-baised eQTL |
| rs4803398 | chr19:40896045:G:C | - | 0.0578832626144819 | 0.0458075647451543 | COAD | Male-baised eQTL |
| rs411073 | chr19:48138317:A:G | - | 0.052569342207666 | 0.0476841220847448 | COAD | Male-baised eQTL |
| rs2288882 | chr19:48135978:G:A | - | 0.0606424045408285 | 0.0495013847512957 | COAD | Male-baised eQTL |
| rs3730974 | chr19:48136437:G:A | - | 0.0606424045408285 | 0.0495013847512957 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000068903 |
| CpG Site: cg10789824 | |
| Position to Gene: gene,exon,UTR | |
| Male Effect: -0.157204806934964 | |
| Female Effect: - | |
 | Gene ID: ENSG00000068903 |
| CpG Site: cg24188561 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.109180117331871 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10789824 | chr19:38878556 | gene,exon,UTR | -0.157204806934964 | 4.71362364337404e-10 | -0.46785340023544236 | 1.575226801858437e-13 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg24188561 | chr19:38897129 | gene | -0.109180117331871 | 5.69403759907663e-07 | -0.36558810846166745 | 5.707267479687234e-09 | LGG |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of SIRT2 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000068903 | SIRT2 | C0525045 | Mood Disorders | 1 | PSYGENET |
| ENSG00000068903 | SIRT2 | C2939186 | Disturbance in mood | 1 | PSYGENET |
