|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000065485 |
Summary for PDIA5 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000065485 | Gene symbol | PDIA5 |
| Gene name | protein disulfide isomerase family A member 5 | |
| HGNC | 24811 | |
| Entrez ID | 10954 | |
| Gene type | protein_coding | |
| Synonyms | PDIA5|PDIR|FLJ30401 | |
| UniProtAcc | Q14554 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PDIA5 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PDIA5 | 2.76e+03 | -1.81e+00 | 2.50e-01 | -7.24e+00 | 4.55e-13 | 1.27e-11 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PDIA5 | 8.21e+02 | -1.35e+00 | 1.80e-01 | -7.53e+00 | 4.89e-14 | 5.30e-13 | KICH |
Top |
Sex-biased somatic mutation for PDIA5 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PDIA5 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg10098541 | chr3:123066803 | CGI:chr3:123066887-123067753 | promoter | 2.88e-01 | 1.70e-01 | 3.11e+00 | 1.85e-03 | 1.31e-02 | 1.18e-01 |
| BRCA | cg26084141 | chr3:123068048 | CGI:chr3:123066887-123067753 | promoter,gene body | 2.63e-01 | 1.63e-01 | 2.37e+00 | 1.77e-02 | 3.34e-02 | 1.00e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg26084141 | chr3:123068048 | CGI:chr3:123066887-123067753 | promoter,gene body | 2.63e-01 | 3.98e-01 | -8.78e+00 | 1.58e-18 | 7.55e-18 | -1.35e-01 |
| HNSC | cg00439384 | chr3:123066711 | CGI:chr3:123066887-123067753 | promoter | 4.07e-01 | 2.60e-01 | 2.69e+00 | 7.10e-03 | 1.57e-02 | 1.47e-01 |
| HNSC | cg10098541 | chr3:123066803 | CGI:chr3:123066887-123067753 | promoter | 3.92e-01 | 2.62e-01 | 2.35e+00 | 1.86e-02 | 2.64e-02 | 1.30e-01 |
| BLCA | cg00439384 | chr3:123066711 | CGI:chr3:123066887-123067753 | promoter | 2.95e-01 | 3.97e-01 | -2.18e+00 | 2.92e-02 | 3.48e-02 | -1.02e-01 |
| BLCA | cg10098541 | chr3:123066803 | CGI:chr3:123066887-123067753 | promoter | 2.70e-01 | 3.76e-01 | -2.51e+00 | 1.22e-02 | 1.98e-02 | -1.06e-01 |
| KIRP | cg00439384 | chr3:123066711 | CGI:chr3:123066887-123067753 | promoter | 2.92e-01 | 1.66e-01 | 3.55e+00 | 3.91e-04 | 2.27e-03 | 1.27e-01 |
Top |
Exon skipping events with PSI in TCGA for PDIA5 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PDIA5 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PDIA5 |
| TFs related to PDIA5. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PDIA5 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PDIA5 |
| RBPs related to ES in PDIA5. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | G3BP2 | exon_skip_377185 | 9.37e+00 | 9.90e-01 | 9.03e+00 | 7.37e-03 | Male-biased |
| LUSC | FMR1 | exon_skip_377178 | 8.43e+00 | 9.43e-03 | 8.79e+00 | 9.85e-01 | Female-biased |
| KIRP | RBM5 | exon_skip_377181 | 8.89e+00 | 2.53e-03 | 9.34e+00 | 9.94e-01 | Female-biased |
| ESCA | FMR1 | exon_skip_377178 | 8.10e+00 | 1.32e-02 | 8.51e+00 | 9.81e-01 | Female-biased |
| ESCA | RBM4 | exon_skip_377193 | 7.97e+00 | 9.82e-01 | 7.53e+00 | 1.01e-02 | Male-biased |
| READ | FMR1 | exon_skip_377178 | 8.35e+00 | 4.39e-03 | 8.75e+00 | 9.90e-01 | Female-biased |
| THCA | FMR1 | exon_skip_377178 | 8.66e+00 | 9.87e-01 | 8.35e+00 | 7.51e-03 | Male-biased |
| PCPG | RBM5 | exon_skip_377181 | 9.05e+00 | 1.47e-02 | 9.34e+00 | 9.82e-01 | Female-biased |
| PCPG | U2AF2 | exon_skip_377175 | 9.39e+00 | 9.94e-01 | 8.97e+00 | 3.32e-03 | Male-biased |
| MESO | U2AF2 | exon_skip_377175 | 8.72e+00 | 1.28e-03 | 9.28e+00 | 9.95e-01 | Female-biased |
| PAAD | RBM5 | exon_skip_377181 | 8.95e+00 | 3.24e-03 | 9.35e+00 | 9.94e-01 | Female-biased |
| PAAD | U2AF2 | exon_skip_377175 | 8.93e+00 | 4.00e-03 | 9.31e+00 | 9.93e-01 | Female-biased |
| SKCM | U2AF2 | exon_skip_377175 | 8.84e+00 | 5.11e-03 | 9.27e+00 | 9.92e-01 | Female-biased |
| PDIA5 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000065485 | AC108134.3,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AL021368.2,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AL390208.1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | FAM66C,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AL359094.1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AC092375.2,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | ITGB1-DT,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | ZNF341-AS1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | FOXD3-AS1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | CCDC18-AS1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | CYTOR,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | HRAT92,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AC091563.1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | MIR497HG,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AC073508.3,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AC099850.1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | ARHGAP27P1-BPTFP1-KPNA2P3,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | RNF213-AS1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AL118505.1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000065485 | AC016026.1,hsa-mir-216a,PDIA5 | Female-specific ceRNA | TCGA-KICH |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6762769 | chr3:132865876:A:G | - | 0.16032809799789 | 0.040592291819537 | GBM | Female-baised eQTL |
| rs2249154 | chr3:132873519:G:A | - | -0.16032809799789 | 0.040592291819537 | GBM | Female-baised eQTL |
| rs1452146 | chr3:132865345:G:A | - | 0.161176830570474 | 0.0482726058072363 | GBM | Female-baised eQTL |
| rs2600960 | chr3:132878078:G:T | - | -0.161176830570474 | 0.0482726058072363 | GBM | Female-baised eQTL |
| rs2712305 | chr3:132878932:T:C | - | -0.161176830570474 | 0.0482726058072363 | GBM | Female-baised eQTL |
| rs4854653 | chr3:132881701:G:A | - | -0.161176830570474 | 0.0482726058072363 | GBM | Female-baised eQTL |
| rs67060255 | chr3:117369326:C:A | - | 0.102408518229575 | 0.0194776191832069 | SARC | Female-baised eQTL |
| rs12631006 | chr3:115421660:T:C | - | 0.292174180554935 | 0.0351254113632162 | KIRP | Female-baised eQTL |
| rs12638811 | chr3:115421661:G:T | - | 0.292174180554935 | 0.0351254113632162 | KIRP | Female-baised eQTL |
| rs7620329 | chr3:118556670:A:G | - | -0.0684121461640246 | 0.0310256514942765 | LGG | Female-baised eQTL |
| rs6438453 | chr3:118556463:C:A | - | -0.0684773187369616 | 0.036915225029136 | LGG | Female-baised eQTL |
| rs6438454 | chr3:118556492:C:G | - | -0.0684773187369616 | 0.036915225029136 | LGG | Female-baised eQTL |
| rs59529658 | chr3:118672815:T:C | - | 0.0791471790248334 | 0.0497017314159272 | LGG | Female-baised eQTL |
| rs6791894 | chr3:114843981:A:G | - | -0.0764662231420982 | 0.00561054154371383 | LUAD | Female-baised eQTL |
| rs9837746 | chr3:114831290:G:A | - | -0.073802522213583 | 0.00817230592466162 | LUAD | Female-baised eQTL |
| rs2056535 | chr3:114801906:A:T | - | -0.0735948962380818 | 0.00866050514183927 | LUAD | Female-baised eQTL |
| rs2140347 | chr3:114813589:G:A | - | -0.0735948962380818 | 0.00866050514183927 | LUAD | Female-baised eQTL |
| rs2399509 | chr3:114814255:C:T | - | -0.0735948962380818 | 0.00866050514183927 | LUAD | Female-baised eQTL |
| rs4146802 | chr3:114847102:A:C | - | -0.0710333418631931 | 0.00997763704639284 | LUAD | Female-baised eQTL |
| rs12490724 | chr3:126548388:C:A | - | -0.0521842480531635 | 0.0133840654816747 | LUAD | Female-baised eQTL |
| rs9868154 | chr3:126546754:A:T | - | 0.0498417138061739 | 0.0196456950070689 | LUAD | Female-baised eQTL |
| rs11713326 | chr3:126549032:G:A | - | -0.0503986777807611 | 0.0218861082262148 | LUAD | Female-baised eQTL |
| rs55668869 | chr3:126549255:C:T | - | -0.0503986777807611 | 0.0218861082262148 | LUAD | Female-baised eQTL |
| rs677754 | chr3:114866157:T:C | - | -0.086020185927876 | 0.0224432521816464 | LUAD | Female-baised eQTL |
| rs672825 | chr3:114868576:C:G | - | -0.086020185927876 | 0.0224432521816464 | LUAD | Female-baised eQTL |
| rs666396 | chr3:114872986:T:C | - | -0.086020185927876 | 0.0224432521816464 | LUAD | Female-baised eQTL |
| rs1589667 | chr3:114805000:C:T | - | -0.0649257804075438 | 0.0247690048971501 | LUAD | Female-baised eQTL |
| rs6803847 | chr3:126549190:T:C | - | -0.0508680987609095 | 0.024956888939369 | LUAD | Female-baised eQTL |
| rs1123373 | chr3:126546863:T:C | - | -0.0443818557766356 | 0.0291955879023172 | LUAD | Female-baised eQTL |
| rs79468740 | chr3:114788083:T:C | - | 0.065998584475322 | 0.0349861156815123 | LUAD | Female-baised eQTL |
| rs16835554 | chr3:124530229:T:C | - | 0.0687848900921239 | 0.0486439981239676 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2034178 | chr3:123014236:G:A | - | 0.287108993643671 | 0.0127415710339524 | PCPG | Male-baised eQTL |
| rs4854645 | chr3:132485966:G:A | - | -0.040254929055938 | 0.0215496227305606 | KIRP | Male-baised eQTL |
| rs6793196 | chr3:132511644:G:A | - | -0.0402465656752878 | 0.0216133118857255 | KIRP | Male-baised eQTL |
| rs754993 | chr3:132525562:G:A | - | -0.0387519713284147 | 0.0335788326132009 | KIRP | Male-baised eQTL |
| rs6767884 | chr3:132545192:T:C | - | -0.0382452095932877 | 0.043172390217858 | KIRP | Male-baised eQTL |
| rs1574733 | chr3:125038474:T:C | - | -0.071135180025048 | 0.0430396340472105 | LGG | Male-baised eQTL |
| rs9852194 | chr3:129423321:G:A | - | -0.0815583630330286 | 0.0208962752568149 | BLCA | Male-baised eQTL |
| rs9873063 | chr3:131675660:C:T | - | -0.0408033496679895 | 0.0250496668709599 | BLCA | Male-baised eQTL |
| rs62263546 | chr3:119198666:C:T | - | 0.0420904532053503 | 0.0282518811040796 | BLCA | Male-baised eQTL |
| rs62263547 | chr3:119199725:G:A | - | 0.0420904532053503 | 0.0282518811040796 | BLCA | Male-baised eQTL |
| rs11709534 | chr3:119196715:T:A | - | 0.042015105909551 | 0.0288259143591424 | BLCA | Male-baised eQTL |
| rs6809166 | chr3:130341116:A:T | - | -0.0506994333058072 | 0.030298252421043 | BLCA | Male-baised eQTL |
| rs9872082 | chr3:129423461:T:C | - | -0.0784891610559242 | 0.0324880418788365 | BLCA | Male-baised eQTL |
| rs9852506 | chr3:129423511:G:A | - | -0.0784891610559242 | 0.0324880418788365 | BLCA | Male-baised eQTL |
| rs9872390 | chr3:129423633:T:A | - | -0.0784891610559242 | 0.0324880418788365 | BLCA | Male-baised eQTL |
| rs9872391 | chr3:129423634:T:A | - | -0.0784891610559242 | 0.0324880418788365 | BLCA | Male-baised eQTL |
| rs9852348 | chr3:129423428:G:A | - | -0.0779534849937953 | 0.0348900445780232 | BLCA | Male-baised eQTL |
| rs9863811 | chr3:129418903:A:G | - | -0.0753963049036627 | 0.0486642874889092 | BLCA | Male-baised eQTL |
| rs11712964 | chr3:126318061:G:T | - | -0.0905953675313979 | 0.023009879630946 | COAD | Male-baised eQTL |
| rs10934492 | chr3:119370923:A:G | - | 0.0855501354584192 | 0.0323288886737584 | COAD | Male-baised eQTL |
| rs147781636 | chr3:119372511:G:A | - | 0.110058540950095 | 0.0368492751611713 | COAD | Male-baised eQTL |
| rs60841305 | chr3:126309809:A:G | - | -0.0861748923477639 | 0.0373781462300554 | COAD | Male-baised eQTL |
| rs17203055 | chr3:119365484:A:G | - | 0.106617687128867 | 0.043942704205429 | COAD | Male-baised eQTL |
| rs79411340 | chr3:119368996:G:A | - | 0.109044452903402 | 0.0440288839990619 | COAD | Male-baised eQTL |
| rs12636459 | chr3:119368987:T:G | - | 0.082138556724002 | 0.045248548913049 | COAD | Male-baised eQTL |
| rs7641045 | chr3:119853012:G:C | - | 0.0510056601861285 | 0.0475520092191089 | COAD | Male-baised eQTL |
| rs9289277 | chr3:126319497:C:A | - | -0.0874680589998219 | 0.0482221695219129 | COAD | Male-baised eQTL |
| rs732737 | chr3:126993915:C:T | - | 0.114286612901919 | 0.0495586662323711 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000065485 |
| CpG Site: cg16720405 | |
| Position to Gene: gene,enhancer | |
| Male Effect: -0.340261681951104 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg16720405 | chr3:123071331 | gene,enhancer | -0.340261681951104 | 8.0981082222231e-05 | -0.3235310147946158 | 7.907460681752991e-07 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_377198 | chr3:123130479:123130616 | Frame-shift | rs111283456 | chr3:122692914:T:C | Distant upstream | -0.124781613299532 | 0.0219568549127286 | PCPG | Male-baised sQTL |
| exon_skip_377198 | chr3:123130479:123130616 | Frame-shift | rs9832142 | chr3:122711091:C:T | Distant upstream | 0.10860723504902 | 0.0461372989142781 | PCPG | Male-baised sQTL |
| exon_skip_377198 | chr3:123130479:123130616 | Frame-shift | rs930123 | chr3:122714715:G:A | Distant upstream | 0.10860723504902 | 0.0461372989142781 | PCPG | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
 | EX ID: exon_skip_377198 |
| CpG Site: cg22707878 | |
| Position to EX: Distant upstream | |
| Male Effect: - | |
| Female Effect: 0.116746334401549 |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| exon_skip_377198 | chr3:123130479:123130616 | cg22707878 | chr3:122886001 | Distant upstream | 0.116746334401549 | 1.22267257388969e-05 | 0.4435982854333532 | 2.692023614960341e-06 | Frame-shift | LIHC |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of PDIA5 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
