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Gene: ENSG00000044524 |
Summary for EPHA3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000044524 | Gene symbol | EPHA3 |
| Gene name | EPH receptor A3 | |
| HGNC | 3387 | |
| Entrez ID | 2042 | |
| Gene type | protein_coding | |
| Synonyms | EPHA3|HEK|HEK4 | |
| UniProtAcc | P29320 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000044524 | EPHA3 | DB12010 | Fostamatinib | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for EPHA3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| EPHA3 | 2.36e+02 | -2.10e+00 | 4.81e-01 | -4.37e+00 | 1.25e-05 | 7.91e-05 | READ |
Top |
Sex-biased somatic mutation for EPHA3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for EPHA3 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg10315231 | chr3:89107418 | CGI:chr3:89114485-89114957 | promoter | 7.40e-02 | 1.85e-01 | -2.41e+00 | 1.61e-02 | 3.22e-02 | -1.11e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg16797972 | chr3:89106921 | CGI:chr3:89114485-89114957 | promoter | 3.56e-01 | 6.67e-01 | -1.03e+01 | 8.46e-25 | 7.05e-24 | -3.11e-01 |
| LUAD | cg16797972 | chr3:89106921 | CGI:chr3:89114485-89114957 | promoter | 4.60e-01 | 6.09e-01 | -2.15e+00 | 3.17e-02 | 3.60e-02 | -1.49e-01 |
| HNSC | cg18055394 | chr3:89107328 | CGI:chr3:89114485-89114957 | promoter | 3.35e-01 | 1.98e-01 | 2.57e+00 | 1.02e-02 | 1.88e-02 | 1.37e-01 |
| COAD | cg05676541 | chr3:89107526 | CGI:chr3:89114485-89114957 | UTR,promoter,exon,gene body | 1.87e-01 | 3.18e-02 | 2.14e+00 | 3.27e-02 | 3.69e-02 | 1.55e-01 |
| LIHC | cg01360628 | chr3:89106968 | CGI:chr3:89114485-89114957 | promoter | 5.73e-01 | 7.18e-01 | 3.78e+00 | 1.59e-04 | 5.46e-04 | -1.45e-01 |
Top |
Exon skipping events with PSI in TCGA for EPHA3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for EPHA3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for EPHA3 |
| TFs related to EPHA3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | NKX6-1 | EPHA3 | 3.65e+00 | 5.22e-03 | 4.65e+00 | 9.91e-01 | Female-biased |
| ACC | POU3F3 | EPHA3 | 4.04e+00 | 1.20e-02 | 4.83e+00 | 9.85e-01 | Female-biased |
| ACC | ZNF418 | EPHA3 | 2.67e+00 | 2.10e-03 | 3.86e+00 | 9.83e-01 | Female-biased |
| BLCA | NKX6-1 | EPHA3 | 4.31e+00 | 1.50e-02 | 5.06e+00 | 9.82e-01 | Female-biased |
| BLCA | POU3F3 | EPHA3 | 4.73e+00 | 1.46e-02 | 5.49e+00 | 9.84e-01 | Female-biased |
| BLCA | ZNF418 | EPHA3 | 2.66e+00 | 1.55e-03 | 3.97e+00 | 9.81e-01 | Female-biased |
| CHOL | ZNF418 | EPHA3 | 3.95e+00 | 6.48e-03 | 5.00e+00 | 9.91e-01 | Female-biased |
| DLBC | EMX1 | EPHA3 | 6.17e+00 | 9.92e-01 | 5.22e+00 | 7.34e-03 | Male-biased |
| DLBC | EMX2 | EPHA3 | 5.98e+00 | 9.94e-01 | 4.97e+00 | 5.64e-03 | Male-biased |
| DLBC | FOXD3 | EPHA3 | 5.36e+00 | 9.96e-01 | 4.03e+00 | 1.74e-03 | Male-biased |
| DLBC | KLF17 | EPHA3 | 2.72e+00 | 2.84e-03 | 3.95e+00 | 9.81e-01 | Female-biased |
| DLBC | MYNN | EPHA3 | 5.23e+00 | 9.95e-01 | 4.01e+00 | 2.58e-03 | Male-biased |
| DLBC | NANOG | EPHA3 | 5.41e+00 | 9.95e-01 | 4.27e+00 | 3.46e-03 | Male-biased |
| DLBC | NFAT5 | EPHA3 | 5.19e+00 | 9.90e-01 | 4.25e+00 | 7.54e-03 | Male-biased |
| DLBC | NKX6-1 | EPHA3 | 5.46e+00 | 9.98e-01 | 3.77e+00 | 5.04e-04 | Male-biased |
| DLBC | POU2F2 | EPHA3 | 5.61e+00 | 9.96e-01 | 4.40e+00 | 2.70e-03 | Male-biased |
| DLBC | POU3F3 | EPHA3 | 5.69e+00 | 9.98e-01 | 4.18e+00 | 9.22e-04 | Male-biased |
| DLBC | POU6F1 | EPHA3 | 6.31e+00 | 9.88e-01 | 5.48e+00 | 1.12e-02 | Male-biased |
| DLBC | REST | EPHA3 | 3.20e+00 | 4.13e-03 | 4.34e+00 | 9.87e-01 | Female-biased |
| DLBC | ZBTB42 | EPHA3 | 3.67e+00 | 8.84e-03 | 4.60e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF141 | EPHA3 | 2.42e+00 | 8.75e-04 | 3.99e+00 | 9.84e-01 | Female-biased |
| DLBC | ZNF317 | EPHA3 | 5.64e+00 | 9.92e-01 | 4.69e+00 | 7.11e-03 | Male-biased |
| DLBC | ZNF354A | EPHA3 | 5.87e+00 | 9.97e-01 | 4.59e+00 | 2.10e-03 | Male-biased |
| DLBC | ZNF354B | EPHA3 | 5.74e+00 | 9.95e-01 | 4.62e+00 | 3.74e-03 | Male-biased |
| DLBC | ZNF418 | EPHA3 | 5.03e+00 | 9.97e-01 | 2.51e+00 | 4.56e-05 | Male-biased |
| LGG | FOXD3 | EPHA3 | 5.18e+00 | 9.82e-01 | 4.79e+00 | 1.58e-02 | Male-biased |
| LGG | NKX6-1 | EPHA3 | 5.21e+00 | 9.85e-01 | 4.78e+00 | 1.28e-02 | Male-biased |
| MESO | POU3F3 | EPHA3 | 4.77e+00 | 9.84e-01 | 3.59e+00 | 1.11e-02 | Male-biased |
| PAAD | ZNF418 | EPHA3 | 5.24e+00 | 9.88e-01 | 4.40e+00 | 9.89e-03 | Male-biased |
| READ | EMX1 | EPHA3 | 5.26e+00 | 9.45e-03 | 6.11e+00 | 9.90e-01 | Female-biased |
| READ | EMX2 | EPHA3 | 4.93e+00 | 5.06e-03 | 5.95e+00 | 9.94e-01 | Female-biased |
| READ | FOXD3 | EPHA3 | 3.60e+00 | 5.47e-04 | 5.26e+00 | 9.97e-01 | Female-biased |
| READ | GTF3A | EPHA3 | 5.08e+00 | 9.96e-01 | 3.66e+00 | 1.05e-03 | Male-biased |
| READ | KLF12 | EPHA3 | 4.99e+00 | 9.96e-01 | 3.58e+00 | 1.05e-03 | Male-biased |
| READ | KLF17 | EPHA3 | 5.14e+00 | 9.97e-01 | 3.21e+00 | 1.61e-04 | Male-biased |
| READ | LIN28B | EPHA3 | 6.27e+00 | 9.83e-01 | 5.56e+00 | 1.62e-02 | Male-biased |
| READ | MYNN | EPHA3 | 3.66e+00 | 1.23e-03 | 5.06e+00 | 9.96e-01 | Female-biased |
| READ | NANOG | EPHA3 | 4.20e+00 | 3.36e-03 | 5.33e+00 | 9.95e-01 | Female-biased |
| READ | NFAT5 | EPHA3 | 4.39e+00 | 1.00e-02 | 5.23e+00 | 9.88e-01 | Female-biased |
| READ | NKX6-1 | EPHA3 | 3.26e+00 | 3.62e-04 | 5.04e+00 | 9.97e-01 | Female-biased |
| READ | NR1H3 | EPHA3 | 4.77e+00 | 9.93e-01 | 3.49e+00 | 1.67e-03 | Male-biased |
| READ | POU2F2 | EPHA3 | 4.29e+00 | 1.70e-03 | 5.61e+00 | 9.97e-01 | Female-biased |
| READ | POU3F3 | EPHA3 | 3.81e+00 | 4.07e-04 | 5.56e+00 | 9.98e-01 | Female-biased |
| READ | POU6F1 | EPHA3 | 5.31e+00 | 9.26e-03 | 6.16e+00 | 9.90e-01 | Female-biased |
| READ | RELA | EPHA3 | 5.24e+00 | 9.94e-01 | 4.12e+00 | 3.19e-03 | Male-biased |
| READ | REST | EPHA3 | 4.98e+00 | 9.96e-01 | 3.43e+00 | 6.19e-04 | Male-biased |
| READ | RREB1 | EPHA3 | 4.31e+00 | 9.88e-01 | 2.90e+00 | 1.00e-03 | Male-biased |
| READ | SALL4 | EPHA3 | 4.19e+00 | 9.86e-01 | 2.56e+00 | 4.36e-04 | Male-biased |
| READ | ZBTB42 | EPHA3 | 5.39e+00 | 9.97e-01 | 3.97e+00 | 1.04e-03 | Male-biased |
| READ | ZNF141 | EPHA3 | 4.85e+00 | 9.96e-01 | 2.82e+00 | 1.02e-04 | Male-biased |
| READ | ZNF317 | EPHA3 | 4.70e+00 | 6.68e-03 | 5.63e+00 | 9.92e-01 | Female-biased |
| READ | ZNF322 | EPHA3 | 4.57e+00 | 9.93e-01 | 2.80e+00 | 2.82e-04 | Male-biased |
| READ | ZNF354A | EPHA3 | 4.30e+00 | 1.42e-03 | 5.67e+00 | 9.97e-01 | Female-biased |
| READ | ZNF354B | EPHA3 | 4.38e+00 | 1.43e-03 | 5.75e+00 | 9.97e-01 | Female-biased |
| READ | ZNF418 | EPHA3 | 8.44e-01 | 1.92e-06 | 4.18e+00 | 9.88e-01 | Female-biased |
| READ | ZNF713 | EPHA3 | 4.62e+00 | 1.21e-02 | 5.40e+00 | 9.86e-01 | Female-biased |
| READ | ZNF749 | EPHA3 | 5.27e+00 | 9.95e-01 | 4.13e+00 | 2.92e-03 | Male-biased |
| READ | ZNF783 | EPHA3 | 4.70e+00 | 9.88e-01 | 3.75e+00 | 5.83e-03 | Male-biased |
| SARC | KLF17 | EPHA3 | 3.31e+00 | 4.13e-03 | 4.11e+00 | 9.84e-01 | Female-biased |
| SARC | ZNF141 | EPHA3 | 3.51e+00 | 5.08e-03 | 4.27e+00 | 9.86e-01 | Female-biased |
| SARC | ZNF418 | EPHA3 | 4.49e+00 | 9.84e-01 | 3.90e+00 | 8.40e-03 | Male-biased |
| SKCM | ZNF418 | EPHA3 | 5.88e+00 | 9.94e-01 | 4.56e+00 | 4.67e-03 | Male-biased |
| EPHA3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for EPHA3 |
| RBPs related to ES in EPHA3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| EPHA3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000044524 | AL513534.2,hsa-mir-410,EPHA3 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000044524 | AC021851.1,hsa-mir-410,EPHA3 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000044524 | AL021368.2,hsa-mir-410,EPHA3 | Female-specific ceRNA | TCGA-KICH |
| ENSG00000044524 | TNFRSF10A-AS1,hsa-mir-410,EPHA3 | Female-specific ceRNA | TCGA-KICH |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6779710 | chr3:89218000:A:G | gene | -0.087328192930232 | 0.038288545684107 | LGG | Female-baised eQTL |
| rs6804377 | chr3:89221937:G:A | gene | -0.0859526765947145 | 0.0390978713777807 | LGG | Female-baised eQTL |
| rs7432305 | chr3:88572464:T:C | - | 0.145966193946478 | 0.0328488837073242 | BLCA | Female-baised eQTL |
| rs199574043 | chr3:88503919:C:T | - | 0.142219543889979 | 0.0451938266124555 | BLCA | Female-baised eQTL |
| rs74431559 | chr3:88506084:T:G | - | 0.142219543889979 | 0.0451938266124555 | BLCA | Female-baised eQTL |
| rs12634801 | chr3:88511011:G:A | - | 0.142219543889979 | 0.0451938266124555 | BLCA | Female-baised eQTL |
| rs11128050 | chr3:88511839:G:A | - | 0.142219543889979 | 0.0451938266124555 | BLCA | Female-baised eQTL |
| rs34482501 | chr3:85540383:C:T | - | 0.0670390741825627 | 0.000486089018362523 | LUAD | Female-baised eQTL |
| rs72895451 | chr3:79948137:C:A | - | 0.067666473950135 | 0.00321933513263748 | LUAD | Female-baised eQTL |
| rs72895446 | chr3:79942241:G:A | - | 0.0666811705156226 | 0.00325538879524246 | LUAD | Female-baised eQTL |
| rs12629494 | chr3:80073277:C:T | - | 0.0640942380881885 | 0.00737676386543935 | LUAD | Female-baised eQTL |
| rs73145251 | chr3:87835642:A:G | - | 0.0622155920630915 | 0.0102866919063012 | LUAD | Female-baised eQTL |
| rs55838662 | chr3:87854899:C:A | - | 0.0622155920630915 | 0.0102866919063012 | LUAD | Female-baised eQTL |
| rs73139501 | chr3:87769348:A:G | - | 0.0625109372325693 | 0.0107615628880046 | LUAD | Female-baised eQTL |
| rs9839585 | chr3:88244988:C:A | - | -0.0436442428126309 | 0.0142010243340595 | LUAD | Female-baised eQTL |
| rs9846207 | chr3:88247177:T:C | - | -0.0436442428126309 | 0.0142010243340595 | LUAD | Female-baised eQTL |
| rs12495727 | chr3:87769693:C:T | - | 0.0596101225903516 | 0.0167939789554222 | LUAD | Female-baised eQTL |
| rs13323436 | chr3:85453695:T:A | - | 0.0483479081061941 | 0.017577042229634 | LUAD | Female-baised eQTL |
| rs12633178 | chr3:79918255:C:T | - | 0.0558431055409546 | 0.0186253561368297 | LUAD | Female-baised eQTL |
| rs6419870 | chr3:88238569:T:C | - | -0.0417573599772955 | 0.0200567115572333 | LUAD | Female-baised eQTL |
| rs7624964 | chr3:88242771:G:A | - | -0.0417573599772955 | 0.0200567115572333 | LUAD | Female-baised eQTL |
| rs6766902 | chr3:88234381:G:A | - | -0.0414577449269667 | 0.0206348745491522 | LUAD | Female-baised eQTL |
| rs6419871 | chr3:88241895:A:C | - | -0.0415649454933684 | 0.0224954140951803 | LUAD | Female-baised eQTL |
| rs72895418 | chr3:79919611:A:C | - | 0.0534321242445797 | 0.0238621358654534 | LUAD | Female-baised eQTL |
| rs74377359 | chr3:87756463:C:T | - | 0.0613647720031188 | 0.0277077093866658 | LUAD | Female-baised eQTL |
| rs77088570 | chr3:87760121:A:T | - | 0.0613647720031188 | 0.0277077093866658 | LUAD | Female-baised eQTL |
| rs79224652 | chr3:87758884:T:G | - | 0.0612564138457935 | 0.0284077726869912 | LUAD | Female-baised eQTL |
| rs12494155 | chr3:87762398:G:A | - | 0.0612564138457935 | 0.0284077726869912 | LUAD | Female-baised eQTL |
| rs80076905 | chr3:88845046:G:C | - | 0.0515037406654682 | 0.0352277171930929 | LUAD | Female-baised eQTL |
| rs9877300 | chr3:85913020:C:T | - | 0.0377696860704313 | 0.040459750683841 | LUAD | Female-baised eQTL |
| rs71316819 | chr3:85908976:G:A | - | 0.0377237481799354 | 0.0411506795982995 | LUAD | Female-baised eQTL |
| rs71316820 | chr3:85909129:G:C | - | 0.0377237481799354 | 0.0411506795982995 | LUAD | Female-baised eQTL |
| rs6774956 | chr3:88884004:C:T | - | 0.0495852097480302 | 0.0458396837138805 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs763900 | chr3:89576295:A:T | - | 0.0907506518383465 | 0.0381332828034398 | LGG | Male-baised eQTL |
| rs17027041 | chr3:89577016:A:T | - | 0.0907506518383465 | 0.0381332828034398 | LGG | Male-baised eQTL |
| rs41404046 | chr3:89590036:C:T | - | 0.0906738060001624 | 0.0387555870024435 | LGG | Male-baised eQTL |
| rs72927439 | chr3:94969180:C:T | - | 0.107424451767326 | 0.0187009116573221 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000044524 |
| CpG Site: cg01360628 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.487316194474017 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01360628 | chr3:89106968 | promoter | -0.487316194474017 | 6.5991855288393e-54 | -0.8339707669975637 | 3.3120180381357066e-58 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of EPHA3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000044524 | EPHA3 | C0004238 | Atrial Fibrillation | 2 | CTD_human |
| ENSG00000044524 | EPHA3 | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
| ENSG00000044524 | EPHA3 | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
| ENSG00000044524 | EPHA3 | C3468561 | familial atrial fibrillation | 2 | CTD_human |
