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Gene: ENSG00000017483 |
Summary for SLC38A5 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000017483 | Gene symbol | SLC38A5 |
| Gene name | solute carrier family 38 member 5 | |
| HGNC | 18070 | |
| Entrez ID | 92745 | |
| Gene type | protein_coding | |
| Synonyms | SLC38A5|SN2|JM24 | |
| UniProtAcc | Q8WUX1 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SLC38A5 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SLC38A5 | 7.64e+02 | 1.87e+00 | 3.11e-01 | 6.03e+00 | 1.65e-09 | 4.14e-09 | KIRC |
| SLC38A5 | 1.42e+03 | 1.84e+00 | 6.16e-01 | 2.99e+00 | 2.78e-03 | 8.00e-03 | BLCA |
| SLC38A5 | 1.55e+03 | 1.18e+00 | 3.90e-01 | 3.03e+00 | 2.48e-03 | 6.27e-03 | STAD |
| SLC38A5 | 1.51e+02 | 2.08e+00 | 6.97e-01 | 2.99e+00 | 2.78e-03 | 8.27e-03 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SLC38A5 | 5.23e+02 | 1.74e+00 | 1.29e-01 | 1.35e+01 | 1.52e-41 | 1.16e-40 | BRCA |
| SLC38A5 | 3.30e+03 | 2.25e+00 | 5.44e-01 | 4.13e+00 | 3.56e-05 | 1.96e-04 | READ |
Top |
Sex-biased somatic mutation for SLC38A5 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SLC38A5 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.84e-01 | 7.13e-01 | -3.48e+00 | 5.09e-04 | 6.14e-03 | -2.29e-01 |
| BRCA | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.68e-01 | 5.94e-01 | -2.17e+00 | 2.98e-02 | 4.08e-02 | -1.26e-01 |
| BRCA | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.91e-01 | 8.34e-01 | -4.06e+00 | 4.82e-05 | 9.50e-04 | -1.44e-01 |
| BRCA | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 7.01e-01 | 8.74e-01 | -4.73e+00 | 2.24e-06 | 5.87e-05 | -1.73e-01 |
| BRCA | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.51e-01 | 8.61e-01 | -2.69e+00 | 7.24e-03 | 2.36e-02 | -1.10e-01 |
| BRCA | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 4.81e-01 | 3.71e-01 | 3.03e+00 | 2.45e-03 | 1.50e-02 | 1.09e-01 |
| LGG | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.60e-01 | 3.95e-02 | 1.88e+01 | 1.73e-78 | 3.48e-77 | 3.21e-01 |
| LGG | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.67e-01 | 7.16e-01 | -8.84e+00 | 9.42e-19 | 6.34e-18 | -1.49e-01 |
| LGG | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.08e-01 | 7.21e-01 | -1.74e+01 | 6.87e-68 | 1.03e-66 | -2.13e-01 |
| LGG | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.71e-01 | 8.19e-01 | -1.40e+01 | 1.03e-44 | 1.02e-43 | -1.48e-01 |
| LGG | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.75e-01 | 8.71e-01 | -1.80e+01 | 1.86e-72 | 3.10e-71 | -1.96e-01 |
| LGG | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.15e-01 | 8.75e-01 | -1.31e+01 | 2.05e-39 | 1.88e-38 | -1.60e-01 |
| LGG | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 8.27e-01 | 9.30e-01 | -1.72e+01 | 5.50e-66 | 7.93e-65 | -1.02e-01 |
| LGG | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 7.72e-01 | 8.84e-01 | -1.38e+01 | 2.74e-43 | 2.65e-42 | -1.12e-01 |
| HNSC | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.00e-01 | 8.05e-01 | -9.18e+00 | 4.37e-20 | 7.30e-19 | -1.05e-01 |
| LUSC | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.26e-01 | 1.40e-01 | 9.07e+00 | 1.22e-19 | 1.25e-18 | 1.85e-01 |
| LUSC | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.68e-01 | 8.05e-01 | -1.09e+01 | 1.20e-27 | 1.48e-26 | -1.37e-01 |
| LUSC | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.13e-01 | 8.25e-01 | -8.02e+00 | 1.07e-15 | 1.01e-14 | -1.12e-01 |
| SKCM | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.14e-01 | 5.54e-01 | -5.41e+00 | 6.25e-08 | 3.46e-07 | -1.40e-01 |
| SKCM | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.82e-01 | 6.01e-01 | -9.60e+00 | 7.98e-22 | 6.42e-21 | -1.19e-01 |
| SKCM | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.31e-01 | 7.56e-01 | -1.02e+01 | 1.39e-24 | 1.20e-23 | -1.25e-01 |
| SKCM | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.50e-01 | 8.01e-01 | -1.20e+01 | 2.20e-33 | 2.28e-32 | -1.51e-01 |
| SKCM | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.17e-01 | 8.65e-01 | -1.17e+01 | 1.34e-31 | 1.34e-30 | -1.48e-01 |
| SKCM | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 7.74e-01 | 9.01e-01 | -1.16e+01 | 4.91e-31 | 4.85e-30 | -1.27e-01 |
| BLCA | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 5.89e-01 | 6.92e-01 | -5.10e+00 | 3.41e-07 | 2.79e-06 | -1.03e-01 |
| STAD | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.35e-01 | 1.36e-01 | 9.85e+00 | 7.12e-23 | 9.15e-22 | 1.99e-01 |
| STAD | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.01e-01 | 8.12e-01 | -7.63e+00 | 2.39e-14 | 2.15e-13 | -1.11e-01 |
| LIHC | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 7.46e-01 | 8.69e-01 | -8.57e+00 | 1.06e-17 | 2.61e-16 | -1.23e-01 |
| SARC | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.27e-01 | 1.22e-01 | 9.06e+00 | 1.26e-19 | 1.71e-18 | 2.05e-01 |
| SARC | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 7.35e-01 | 6.23e-01 | 2.50e+00 | 1.25e-02 | 2.13e-02 | 1.12e-01 |
| SARC | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.63e-01 | 5.88e-01 | -7.27e+00 | 3.63e-13 | 3.73e-12 | -1.25e-01 |
| SARC | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.56e-01 | 8.03e-01 | -8.40e+00 | 4.63e-17 | 5.64e-16 | -1.47e-01 |
| SARC | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 6.29e-01 | 7.51e-01 | -4.93e+00 | 8.09e-07 | 5.76e-06 | -1.22e-01 |
| SARC | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 8.06e-01 | 9.15e-01 | -8.96e+00 | 3.12e-19 | 4.16e-18 | -1.09e-01 |
| PCPG | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 2.04e-01 | 2.90e-02 | 1.10e+01 | 3.29e-28 | 5.21e-27 | 1.75e-01 |
| PCPG | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.15e-01 | 4.86e-01 | 2.88e+00 | 3.98e-03 | 1.21e-02 | 1.30e-01 |
| PCPG | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.28e-01 | 3.00e-01 | 4.69e+00 | 2.74e-06 | 1.28e-05 | 1.29e-01 |
| PCPG | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.91e-01 | 5.11e-01 | -4.93e+00 | 8.07e-07 | 3.86e-06 | -1.20e-01 |
| PCPG | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 4.70e-01 | 5.94e-01 | -4.72e+00 | 2.39e-06 | 1.12e-05 | -1.24e-01 |
| PAAD | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.73e-01 | 7.78e-02 | 9.81e+00 | 9.84e-23 | 1.66e-21 | 2.95e-01 |
| PAAD | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.60e-01 | 5.02e-01 | 5.05e+00 | 4.48e-07 | 3.02e-06 | 1.58e-01 |
| PAAD | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.44e-01 | 3.73e-01 | 6.44e+00 | 1.18e-10 | 9.97e-10 | 1.71e-01 |
| READ | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 2.42e-01 | 5.52e-02 | 7.14e+00 | 9.65e-13 | 9.47e-12 | 1.86e-01 |
| READ | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.66e-01 | 2.76e-01 | 5.50e+00 | 3.80e-08 | 2.55e-07 | 2.90e-01 |
| READ | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.85e-01 | 2.40e-01 | 5.51e+00 | 3.51e-08 | 2.36e-07 | 2.45e-01 |
| READ | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 6.13e-01 | 8.03e-01 | -5.39e+00 | 7.23e-08 | 4.71e-07 | -1.90e-01 |
| GBM | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.64e-01 | 5.08e-02 | 6.18e+00 | 6.39e-10 | 6.59e-09 | 3.14e-01 |
| GBM | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.63e-01 | 4.82e-01 | 1.99e+00 | 4.70e-02 | 4.81e-02 | 1.81e-01 |
| GBM | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.20e-01 | 5.85e-01 | -4.81e+00 | 1.54e-06 | 1.02e-05 | -1.65e-01 |
| GBM | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.66e-01 | 6.97e-01 | -3.57e+00 | 3.58e-04 | 1.59e-03 | -1.31e-01 |
| GBM | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.62e-01 | 8.16e-01 | -4.79e+00 | 1.65e-06 | 1.09e-05 | -1.53e-01 |
| GBM | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 5.92e-01 | 7.92e-01 | -3.38e+00 | 7.38e-04 | 3.07e-03 | -2.00e-01 |
| GBM | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 8.32e-01 | 9.41e-01 | -6.00e+00 | 1.97e-09 | 1.87e-08 | -1.09e-01 |
| ESCA | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.06e-01 | 1.58e-01 | 4.20e+00 | 2.71e-05 | 1.58e-04 | 1.48e-01 |
| ESCA | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 6.66e-01 | 8.02e-01 | -4.30e+00 | 1.73e-05 | 1.03e-04 | -1.35e-01 |
| LAML | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.75e-01 | 3.29e-02 | 1.00e+01 | 1.58e-23 | 3.64e-22 | 3.42e-01 |
| LAML | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 2.50e-01 | 5.68e-02 | 7.01e+00 | 2.44e-12 | 1.23e-11 | 1.94e-01 |
| LAML | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.52e-01 | 6.80e-02 | 1.00e+01 | 1.12e-23 | 3.15e-22 | 4.84e-01 |
| LAML | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.05e-01 | 6.66e-02 | 9.96e+00 | 2.33e-23 | 4.39e-22 | 4.38e-01 |
| THYM | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.66e-01 | 2.56e-02 | 9.36e+00 | 7.81e-21 | 1.15e-19 | 3.41e-01 |
| THYM | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 1.96e-01 | 9.50e-02 | 5.26e+00 | 1.48e-07 | 5.53e-07 | 1.01e-01 |
| THYM | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.08e-01 | 2.30e-01 | 7.17e+00 | 7.47e-13 | 3.94e-12 | 3.78e-01 |
| THYM | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.18e-01 | 1.64e-01 | 8.35e+00 | 6.74e-17 | 5.00e-16 | 3.54e-01 |
| THYM | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 7.19e-01 | 8.92e-01 | -8.46e+00 | 2.60e-17 | 2.05e-16 | -1.73e-01 |
| MESO | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.48e-01 | 8.95e-02 | 4.89e+00 | 1.02e-06 | 8.14e-06 | 2.59e-01 |
| MESO | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.92e-01 | 6.08e-01 | -3.45e+00 | 5.52e-04 | 2.97e-03 | -1.15e-01 |
| MESO | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 7.04e-01 | 8.11e-01 | -3.29e+00 | 9.86e-04 | 4.97e-03 | -1.07e-01 |
| UVM | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.65e-01 | 1.94e-01 | 3.67e+00 | 2.42e-04 | 8.08e-04 | 1.72e-01 |
| UVM | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.59e-01 | 7.19e-01 | -2.85e+00 | 4.42e-03 | 1.14e-02 | -1.60e-01 |
| UVM | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.88e-01 | 7.72e-01 | -6.89e+00 | 5.55e-12 | 5.21e-11 | -1.85e-01 |
| UVM | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.82e-01 | 8.81e-01 | -5.68e+00 | 1.36e-08 | 8.13e-08 | -2.00e-01 |
| UVM | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 7.20e-01 | 8.93e-01 | -5.77e+00 | 8.13e-09 | 5.13e-08 | -1.73e-01 |
| UVM | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 8.09e-01 | 9.27e-01 | -3.60e+00 | 3.15e-04 | 1.03e-03 | -1.18e-01 |
| ACC | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.48e-01 | 7.04e-01 | -3.15e+00 | 1.62e-03 | 7.76e-03 | -1.56e-01 |
| ACC | cg03021892 | chrX:48470890 | CGI:chrX:48475841-48476648 | promoter | 7.59e-01 | 9.12e-01 | -5.00e+00 | 5.73e-07 | 4.90e-06 | -1.53e-01 |
| ACC | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 7.15e-01 | 8.38e-01 | -4.82e+00 | 1.44e-06 | 1.19e-05 | -1.24e-01 |
| ACC | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.84e-01 | 8.99e-01 | -6.89e+00 | 5.67e-12 | 8.35e-11 | -2.15e-01 |
| ACC | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 7.85e-01 | 9.29e-01 | -6.63e+00 | 3.44e-11 | 4.51e-10 | -1.45e-01 |
| ACC | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.08e-01 | 7.03e-01 | -5.47e+00 | 4.45e-08 | 4.22e-07 | -1.95e-01 |
| ACC | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 8.11e-01 | 9.47e-01 | -6.50e+00 | 8.25e-11 | 1.03e-09 | -1.36e-01 |
| KICH | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 2.32e-01 | 4.92e-02 | 5.89e+00 | 3.82e-09 | 4.77e-08 | 1.83e-01 |
| KICH | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.28e-01 | 3.44e-01 | 2.96e+00 | 3.08e-03 | 1.29e-02 | 1.84e-01 |
| KICH | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.97e-01 | 1.67e-01 | 4.99e+00 | 5.89e-07 | 5.46e-06 | 2.30e-01 |
| DLBC | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 2.50e-01 | 2.25e-02 | 5.90e+00 | 3.70e-09 | 5.58e-08 | 2.28e-01 |
| DLBC | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.79e-01 | 1.27e-01 | 5.32e+00 | 1.05e-07 | 1.01e-06 | 3.52e-01 |
| DLBC | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 3.90e-01 | 1.03e-01 | 5.32e+00 | 1.05e-07 | 1.01e-06 | 2.87e-01 |
| CHOL | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.45e-01 | 2.11e-01 | 2.74e+00 | 6.18e-03 | 1.53e-02 | 2.33e-01 |
| CHOL | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.88e-01 | 6.73e-01 | -4.23e+00 | 2.29e-05 | 1.38e-04 | -1.84e-01 |
| CHOL | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.77e-01 | 7.92e-01 | -2.77e+00 | 5.61e-03 | 1.43e-02 | -1.15e-01 |
| CHOL | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 7.17e-01 | 8.85e-01 | -4.49e+00 | 7.16e-06 | 5.07e-05 | -1.68e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.90e-01 | 7.39e-01 | -5.83e+00 | 5.68e-09 | 4.60e-08 | -1.49e-01 |
| KIRC | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.98e-01 | 8.40e-01 | -5.10e+00 | 3.48e-07 | 1.46e-06 | -1.43e-01 |
| KIRC | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 8.41e-01 | 7.27e-01 | 5.18e+00 | 2.26e-07 | 1.00e-06 | 1.14e-01 |
| LUSC | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.57e-01 | 6.04e-01 | -4.00e+00 | 6.24e-05 | 5.89e-04 | -1.46e-01 |
| LUSC | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 6.13e-01 | 8.93e-01 | -4.05e+00 | 5.10e-05 | 5.60e-04 | -2.80e-01 |
| LUSC | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 5.01e-01 | 7.33e-01 | -4.09e+00 | 4.34e-05 | 5.42e-04 | -2.32e-01 |
| COAD | cg21197919 | chrX:48470306 | CGI:chrX:48475841-48476648 | promoter | 5.83e-01 | 7.04e-01 | -2.36e+00 | 1.83e-02 | 2.31e-02 | -1.21e-01 |
| BLCA | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.36e-01 | 5.96e-01 | -4.21e+00 | 2.54e-05 | 1.61e-04 | -1.60e-01 |
| BLCA | cg16175497 | chrX:48470203 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.10e-01 | 7.26e-01 | -2.40e+00 | 1.64e-02 | 2.09e-02 | -1.16e-01 |
| BLCA | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 6.98e-01 | 8.33e-01 | -2.96e+00 | 3.12e-03 | 5.58e-03 | -1.35e-01 |
| LIHC | cg19407886 | chrX:48469899 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 4.56e-01 | 6.31e-01 | -5.81e+00 | 6.34e-09 | 5.51e-08 | -1.75e-01 |
| LIHC | cg16536563 | chrX:48470387 | CGI:chrX:48475841-48476648 | promoter | 7.04e-01 | 8.78e-01 | -5.44e+00 | 5.35e-08 | 3.13e-07 | -1.74e-01 |
| KIRP | cg02151779 | chrX:48469487 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.55e-01 | 3.14e-01 | 3.64e+00 | 2.75e-04 | 6.09e-04 | 2.41e-01 |
| KIRP | cg17590101 | chrX:48469361 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 6.63e-01 | 4.38e-01 | 3.65e+00 | 2.66e-04 | 5.93e-04 | 2.25e-01 |
| KIRP | cg20495737 | chrX:48469380 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 5.60e-01 | 2.99e-01 | 4.45e+00 | 8.68e-06 | 3.31e-05 | 2.61e-01 |
| KIRP | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 8.82e-01 | 7.72e-01 | 5.34e+00 | 9.38e-08 | 8.03e-07 | 1.09e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 5.54e-01 | 7.01e-01 | -9.43e+00 | 3.97e-21 | 2.36e-20 | -1.48e-01 |
| BRCA | cg18492059 | chrX:48471597 | CGI:chrX:48475841-48476648 | promoter | 4.81e-01 | 5.96e-01 | -8.70e+00 | 3.38e-18 | 1.58e-17 | -1.15e-01 |
| LUAD | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 7.69e-01 | 8.84e-01 | -2.80e+00 | 5.03e-03 | 9.66e-03 | -1.15e-01 |
| COAD | cg24152857 | chrX:48468263 | CGI:chrX:48475841-48476648 | UTR,promoter,exon,gene body | 2.74e-01 | 4.45e-01 | -3.73e+00 | 1.93e-04 | 9.81e-04 | -1.71e-01 |
| LIHC | cg26735834 | chrX:48471587 | CGI:chrX:48475841-48476648 | promoter | 7.46e-01 | 8.64e-01 | -2.43e+00 | 1.52e-02 | 1.94e-02 | -1.18e-01 |
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Exon skipping events with PSI in TCGA for SLC38A5 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for SLC38A5 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for SLC38A5 |
| TFs related to SLC38A5. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SARC | PLAGL2 | SLC38A5 | 4.05e+00 | 9.83e-01 | 3.17e+00 | 1.50e-03 | Male-biased |
| SLC38A5 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for SLC38A5 |
| RBPs related to ES in SLC38A5. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SLC38A5 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg20495737 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.119806865915904 | |
| Female Effect: - | |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg17590101 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.138332098585768 | |
| Female Effect: - | |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg20495737 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.086202704945372 | |
| Female Effect: - | |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg17590101 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.0465635404582301 | |
| Female Effect: - | |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg20495737 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.0422963106485508 | |
| Female Effect: - | |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg20495737 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.0799490483040049 | |
| Female Effect: - | |
 | Gene ID: ENSG00000017483 |
| CpG Site: cg17590101 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.0769632350160966 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg20495737 | chrX:48469380 | gene,exon,promoter,UTR | -0.119806865915904 | 5.25645922787415e-11 | -0.552037172078844 | 1.0512703580531553e-14 | COAD |
| cg17590101 | chrX:48469361 | gene,exon,promoter,UTR | -0.138332098585768 | 4.71973623803075e-05 | -0.3400475893663773 | 2.3424828042998932e-07 | LUAD |
| cg20495737 | chrX:48469380 | gene,exon,promoter,UTR | -0.086202704945372 | 5.74991420340938e-05 | -0.3426278825010872 | 1.5420308969918226e-07 | LUAD |
| cg17590101 | chrX:48469361 | gene,exon,promoter,UTR | -0.0465635404582301 | 2.87466543199274e-05 | -0.3155824781811572 | 8.954307098359424e-08 | LUSC |
| cg20495737 | chrX:48469380 | gene,exon,promoter,UTR | -0.0422963106485508 | 6.26712222760646e-05 | -0.3016946912693306 | 3.4042840256689783e-07 | LUSC |
| cg20495737 | chrX:48469380 | gene,exon,promoter,UTR | -0.0799490483040049 | 4.31846967159107e-15 | -0.4457660275731934 | 2.290561743102683e-19 | HNSC |
| cg17590101 | chrX:48469361 | gene,exon,promoter,UTR | -0.0769632350160966 | 1.59747313135094e-12 | -0.41050459839964126 | 2.159712197748592e-16 | HNSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of SLC38A5 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
