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Gene: ENSG00000010803 |
Summary for SCMH1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000010803 | Gene symbol | SCMH1 |
| Gene name | Scm polycomb group protein homolog 1 | |
| HGNC | 19003 | |
| Entrez ID | 22955 | |
| Gene type | protein_coding | |
| Synonyms | SCMH1|Scml3 | |
| UniProtAcc | Q96GD3 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000010803 | SCMH1 | DB03345 | Mercaptoethanol | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SCMH1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for SCMH1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SCMH1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg00826203 | chr1:41241135 | CGI:chr1:41241285-41242655 | promoter,gene body | 2.97e-01 | 1.42e-01 | 3.45e+00 | 5.63e-04 | 1.20e-03 | 1.55e-01 |
| HNSC | cg03387723 | chr1:41242792 | CGI:chr1:41241285-41242655 | promoter | 6.10e-01 | 7.55e-01 | -4.06e+00 | 4.88e-05 | 1.42e-04 | -1.46e-01 |
| LUSC | cg00826203 | chr1:41241135 | CGI:chr1:41241285-41242655 | promoter,gene body | 2.80e-01 | 1.47e-01 | 3.50e+00 | 4.66e-04 | 1.59e-03 | 1.33e-01 |
| LUSC | cg03387723 | chr1:41242792 | CGI:chr1:41241285-41242655 | promoter | 5.77e-01 | 7.96e-01 | -4.12e+00 | 3.84e-05 | 5.32e-04 | -2.19e-01 |
| ESCA | cg00826203 | chr1:41241135 | CGI:chr1:41241285-41242655 | promoter,gene body | 2.71e-01 | 1.35e-01 | 2.89e+00 | 3.87e-03 | 3.38e-02 | 1.36e-01 |
| ESCA | cg03387723 | chr1:41242792 | CGI:chr1:41241285-41242655 | promoter | 6.43e-01 | 8.02e-01 | -2.75e+00 | 5.96e-03 | 3.48e-02 | -1.59e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg00826203 | chr1:41241135 | CGI:chr1:41241285-41242655 | promoter,gene body | 2.50e-01 | 1.36e-01 | 2.63e+00 | 8.51e-03 | 9.72e-03 | 1.14e-01 |
| BLCA | cg00826203 | chr1:41241135 | CGI:chr1:41241285-41242655 | promoter,gene body | 3.16e-01 | 1.95e-01 | 2.16e+00 | 3.08e-02 | 3.60e-02 | 1.21e-01 |
| LIHC | cg00826203 | chr1:41241135 | CGI:chr1:41241285-41242655 | promoter,gene body | 2.30e-01 | 1.26e-01 | 4.00e+00 | 6.27e-05 | 2.70e-04 | 1.04e-01 |
Top |
Exon skipping events with PSI in TCGA for SCMH1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| KIRC | exon_skip_25518 | 4.03e-01 | 2.82e-01 | 6.42e+00 | 1.39e-10 | 2.74e-09 | 1.21e-01 |
| STAD | exon_skip_25512 | 6.08e-01 | 7.19e-01 | -2.16e+00 | 3.05e-02 | 3.81e-02 | -1.11e-01 |
| ESCA | exon_skip_25512 | 5.62e-01 | 7.51e-01 | -2.00e+00 | 4.59e-02 | 4.77e-02 | -1.89e-01 |
| KICH | exon_skip_25526 | 7.24e-01 | 6.17e-01 | 2.58e+00 | 1.00e-02 | 1.99e-02 | 1.08e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| LUSC | exon_skip_25431 | 4.51e-01 | 5.81e-01 | -3.62e+00 | 2.97e-04 | 1.12e-03 | -1.30e-01 |
Top |
RNA A-to-I editing events in TCGA for SCMH1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
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| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LUAD | SCMH1-001 | chr1_41164873_- | 2.16e-01 | 1.66e-01 | 3.13e+00 | 1.75e-03 | 1.97e-02 | 4.96e-02 |
| STAD | SCMH1-011 | chr1_41234613_- | 6.54e-01 | 4.29e-01 | 2.32e+00 | 2.02e-02 | 4.96e-02 | 2.26e-01 |
| LAML | SCMH1-001 | chr1_41164994_- | 2.56e-01 | 1.81e-01 | 2.81e+00 | 5.01e-03 | 4.94e-02 | 7.51e-02 |
| LAML | SCMH1-001 | chr1_41164998_- | 2.76e-01 | 1.65e-01 | 2.70e+00 | 6.95e-03 | 4.94e-02 | 1.11e-01 |
| LAML | SCMH1-001 | chr1_41174182_- | 2.14e-01 | 1.71e-01 | 2.09e+00 | 3.62e-02 | 4.94e-02 | 4.28e-02 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for SCMH1 |
| TFs related to SCMH1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SCMH1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SCMH1 |
| RBPs related to ES in SCMH1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | HNRNPH2 | exon_skip_25434 | 5.69e+00 | 7.66e-04 | 6.44e+00 | 9.80e-01 | Female-biased |
| UVM | ZC3H10 | exon_skip_25509 | 7.31e+00 | 9.84e-01 | 6.95e+00 | 4.50e-03 | Male-biased |
| LUSC | NOVA2 | exon_skip_25427 | 9.27e+00 | 1.52e-02 | 9.59e+00 | 9.82e-01 | Female-biased |
| COAD | NOVA2 | exon_skip_25427 | 9.22e+00 | 6.36e-03 | 9.59e+00 | 9.91e-01 | Female-biased |
| KIRP | NOVA2 | exon_skip_25427 | 9.24e+00 | 7.37e-03 | 9.60e+00 | 9.90e-01 | Female-biased |
| ESCA | PCBP2 | exon_skip_25526 | 7.75e+00 | 3.86e-03 | 8.31e+00 | 9.89e-01 | Female-biased |
| READ | NOVA2 | exon_skip_25427 | 9.59e+00 | 9.92e-01 | 9.22e+00 | 5.97e-03 | Male-biased |
| THCA | ZFP36 | exon_skip_25447 | 7.03e+00 | 4.58e-03 | 7.38e+00 | 9.85e-01 | Female-biased |
| PCPG | ESRP2 | exon_skip_25458 | 8.45e+00 | 9.84e-01 | 8.13e+00 | 9.37e-03 | Male-biased |
| GBM | NOVA2 | exon_skip_25427 | 9.29e+00 | 1.14e-02 | 9.62e+00 | 9.86e-01 | Female-biased |
| GBM | PABPN1 | exon_skip_25496 | 9.14e+00 | 1.27e-02 | 9.46e+00 | 9.84e-01 | Female-biased |
| GBM | RBM6 | exon_skip_25501 | 7.84e+00 | 3.12e-03 | 8.29e+00 | 9.89e-01 | Female-biased |
| KIRC | ZC3H10 | exon_skip_25509 | 7.73e+00 | 9.89e-01 | 7.28e+00 | 1.72e-03 | Male-biased |
| KICH | NOVA2 | exon_skip_25427 | 9.26e+00 | 8.95e-03 | 9.59e+00 | 9.88e-01 | Female-biased |
| SCMH1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs141773832 | chr1:43128680:C:T | - | 0.14323623210714 | 0.0128333995992583 | LUSC | Female-baised eQTL |
| rs12030306 | chr1:43147248:T:C | - | 0.139310820781969 | 0.0309034423595673 | LUSC | Female-baised eQTL |
| rs12037607 | chr1:43157610:G:A | - | 0.139310820781969 | 0.0309034423595673 | LUSC | Female-baised eQTL |
| rs545670 | chr1:47476750:T:C | - | -0.0369276481009095 | 0.0442359538721164 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2008713 | chr1:47236696:T:C | - | -0.0499182402872061 | 0.0253544426339703 | KIRC | Male-baised eQTL |
| rs16827976 | chr1:41191983:C:A | gene | 0.0958277059008081 | 0.00664279250200881 | LUAD | Male-baised eQTL |
| rs2300648 | chr1:41103816:T:C | gene | 0.0877930082088996 | 0.00826745109544028 | LUAD | Male-baised eQTL |
| rs78230118 | chr1:41039966:A:T | gene | 0.0871847679772667 | 0.0163962244147392 | LUAD | Male-baised eQTL |
| rs11209523 | chr1:41100786:G:A | gene | 0.0846445578568785 | 0.01717727164631 | LUAD | Male-baised eQTL |
| rs943372 | chr1:41668182:G:A | - | 0.0668539588272187 | 0.0179893535430903 | LUAD | Male-baised eQTL |
| rs12119252 | chr1:41029736:A:G | gene | 0.0826201472066699 | 0.0257579211634739 | LUAD | Male-baised eQTL |
| rs3766321 | chr1:41100182:C:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs3766323 | chr1:41100424:T:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209524 | chr1:41101109:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs2300647 | chr1:41103890:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11583704 | chr1:41105490:T:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209541 | chr1:41108491:C:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12132884 | chr1:41112250:T:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209553 | chr1:41114514:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs35318873 | chr1:41114591:C:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209555 | chr1:41114785:T:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11587407 | chr1:41114970:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209556 | chr1:41115531:G:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209562 | chr1:41116701:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209563 | chr1:41116798:T:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209565 | chr1:41117088:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs61634214 | chr1:41118024:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs2284802 | chr1:41119080:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12138245 | chr1:41120262:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs79065897 | chr1:41128597:G:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12135481 | chr1:41130213:T:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12137481 | chr1:41138240:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12125884 | chr1:41150134:C:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12118372 | chr1:41150616:G:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs2300646 | chr1:41153040:T:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs16827938 | chr1:41154644:C:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs28533882 | chr1:41155193:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs2300644 | chr1:41157279:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209604 | chr1:41161534:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs78824553 | chr1:41165181:T:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs77341961 | chr1:41171621:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12127968 | chr1:41173411:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12406305 | chr1:41173863:G:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209615 | chr1:41174438:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11584802 | chr1:41175014:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs79288972 | chr1:41180531:A:C | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12410899 | chr1:41184550:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs75149368 | chr1:41187164:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11577984 | chr1:41194436:C:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12402868 | chr1:41194986:C:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209683 | chr1:41204568:T:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs10889890 | chr1:41209877:G:A | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11209701 | chr1:41213077:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11579915 | chr1:41224053:A:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12138221 | chr1:41227719:C:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs11585600 | chr1:41234783:C:G | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs10493094 | chr1:41237270:G:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12126982 | chr1:41239838:G:T | gene | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12130655 | chr1:41245667:T:C | enhancer | 0.082306174550754 | 0.0267199201503288 | LUAD | Male-baised eQTL |
| rs12140747 | chr1:41117403:G:A | gene | 0.082270710638264 | 0.0269609198148222 | LUAD | Male-baised eQTL |
| rs143747274 | chr1:41084701:A:G | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs7532795 | chr1:41084992:G:A | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs78317722 | chr1:41086355:G:C | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs75382370 | chr1:41087202:C:G | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs112041001 | chr1:41090062:G:A | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs12354019 | chr1:41090895:T:C | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs200867799 | chr1:41091611:G:A | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs141444909 | chr1:41093035:A:G | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs11582011 | chr1:41094784:G:A | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs11580620 | chr1:41094899:A:T | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs12124836 | chr1:41099382:T:C | gene | 0.0822152764232615 | 0.0272152617613852 | LUAD | Male-baised eQTL |
| rs11209752 | chr1:41251172:T:C | - | 0.0821514110562253 | 0.0274629644372265 | LUAD | Male-baised eQTL |
| rs138186324 | chr1:41252995:C:T | - | 0.0821514110562253 | 0.0274629644372265 | LUAD | Male-baised eQTL |
| rs112268756 | chr1:41256817:G:C | - | 0.0821514110562253 | 0.0274629644372265 | LUAD | Male-baised eQTL |
| rs12136824 | chr1:41257785:A:T | - | 0.0821514110562253 | 0.0274629644372265 | LUAD | Male-baised eQTL |
| rs11577910 | chr1:41011772:G:A | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs113457358 | chr1:41019016:A:G | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs6661890 | chr1:41021820:C:G | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs6674450 | chr1:41021949:A:C | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11209368 | chr1:41023050:T:G | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs12127969 | chr1:41024139:G:A | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs6688028 | chr1:41025681:A:C | - | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs12120043 | chr1:41030057:A:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs111423979 | chr1:41032928:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs74545213 | chr1:41033868:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11585876 | chr1:41034536:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11580656 | chr1:41034906:A:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11209380 | chr1:41035069:C:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs2300659 | chr1:41039169:G:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs2300657 | chr1:41042283:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11587742 | chr1:41043000:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs2268681 | chr1:41044667:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs2268679 | chr1:41045293:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs12406656 | chr1:41047308:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs12406942 | chr1:41047309:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs113157208 | chr1:41049698:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs78214821 | chr1:41050591:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs79733953 | chr1:41050919:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs75693318 | chr1:41052499:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs12144169 | chr1:41053178:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11209409 | chr1:41053474:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs78115019 | chr1:41056790:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs112387309 | chr1:41058447:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs79481015 | chr1:41059085:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11585719 | chr1:41060706:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11586714 | chr1:41062517:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs28787055 | chr1:41063284:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs77431926 | chr1:41065784:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs2144789 | chr1:41066557:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs78234046 | chr1:41067803:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs111373347 | chr1:41068649:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs2300653 | chr1:41069507:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs12145015 | chr1:41074515:T:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs41269465 | chr1:41075494:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs10889828 | chr1:41076552:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11577885 | chr1:41076582:G:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs77871359 | chr1:41076760:T:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs7512622 | chr1:41081699:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs7523163 | chr1:41081852:G:C | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs11576982 | chr1:41082888:A:G | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs142005767 | chr1:41083245:T:A | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs200325123 | chr1:41083656:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs201156864 | chr1:41083706:C:T | gene | 0.0819357442586331 | 0.0284974801204673 | LUAD | Male-baised eQTL |
| rs189673170 | chr1:41117549:C:T | gene | 0.0818160812091604 | 0.028932200356601 | LUAD | Male-baised eQTL |
| rs1536935 | chr1:41108295:T:C | gene | 0.0816080343939854 | 0.0299324046328301 | LUAD | Male-baised eQTL |
| rs60683385 | chr1:41176612:C:A | gene | 0.0815756714798359 | 0.0301791283008607 | LUAD | Male-baised eQTL |
| rs11209367 | chr1:41022834:C:T | - | 0.0797493753113361 | 0.0354877119151371 | LUAD | Male-baised eQTL |
| rs2275930 | chr1:41264524:T:G | - | 0.0794626612405481 | 0.0365941123824904 | LUAD | Male-baised eQTL |
| rs12118423 | chr1:41267983:C:T | - | 0.0794626612405481 | 0.0365941123824904 | LUAD | Male-baised eQTL |
| rs11209778 | chr1:41270916:C:G | - | 0.0794626612405481 | 0.0365941123824904 | LUAD | Male-baised eQTL |
| rs12127849 | chr1:41276961:C:T | - | 0.0794626612405481 | 0.0365941123824904 | LUAD | Male-baised eQTL |
| rs11209787 | chr1:41277798:G:A | - | 0.0794626612405481 | 0.0365941123824904 | LUAD | Male-baised eQTL |
| rs41308258 | chr1:41007611:A:G | - | 0.0750200141171977 | 0.037196204490567 | LUAD | Male-baised eQTL |
| rs34767929 | chr1:41572944:A:G | - | 0.0650417315124766 | 0.0413346321866176 | LUAD | Male-baised eQTL |
| rs16828535 | chr1:41676802:G:A | - | 0.0784412365334801 | 0.0463582453193884 | LUAD | Male-baised eQTL |
| rs12119675 | chr1:40993018:C:T | - | 0.0800000968998565 | 0.0472453167046111 | LUAD | Male-baised eQTL |
| rs57734798 | chr1:40996841:A:G | - | 0.0800000968998565 | 0.0472453167046111 | LUAD | Male-baised eQTL |
| rs112703871 | chr1:40998200:C:T | - | 0.0800000968998565 | 0.0472453167046111 | LUAD | Male-baised eQTL |
| rs1343777 | chr1:41292183:A:G | - | 0.0769513119162958 | 0.0490546958294813 | LUAD | Male-baised eQTL |
| rs78189938 | chr1:40990781:A:G | - | 0.079711538917392 | 0.0492187852000382 | LUAD | Male-baised eQTL |
| rs111580163 | chr1:41040724:C:T | gene | 0.0754348010919179 | 0.0495197015760652 | LUAD | Male-baised eQTL |
| rs4652993 | chr1:34158779:T:A | - | 0.113092849302976 | 0.04196322037417 | COAD | Male-baised eQTL |
| rs194656 | chr1:32957605:G:A | - | -0.0666230415234816 | 0.0433145562287834 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000010803 |
| CpG Site: cg15962197 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.444880935501275 | |
 | Gene ID: ENSG00000010803 |
| CpG Site: cg03387723 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.444880935501275 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg15962197 | chr1:41238889 | gene | -0.444880935501275 | 6.00976664187596e-37 | -0.7187580545006401 | 8.036849439576674e-42 | LUAD |
| cg03387723 | chr1:41242792 | promoter | -0.444880935501275 | 6.00976664187596e-37 | -0.7187580545006401 | 8.036849439576674e-42 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs61779235 | chr1:40685296:T:A | Distant downstream | 0.0377309657589753 | 0.0270489000961198 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs10789187 | chr1:40689501:T:C | Distant downstream | 0.0368507532871856 | 0.0318131129028413 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs10789191 | chr1:40690819:C:G | Distant downstream | 0.0361776456832302 | 0.0385073266010074 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs7519348 | chr1:40694532:A:G | Distant downstream | 0.0361776456832302 | 0.0385073266010074 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs61779236 | chr1:40685299:T:A | Distant downstream | 0.0356801321528577 | 0.0440066363234237 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs61779237 | chr1:40685300:A:T | Distant downstream | 0.0356801321528577 | 0.0440066363234237 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs2769255 | chr1:40779682:C:T | Distant downstream | -0.0369393124959951 | 0.0440278396527103 | LUAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs2780947 | chr1:40779298:G:A | Distant downstream | -0.0367017101533426 | 0.0460742318797257 | LUAD | Female-baised sQTL |
| exon_skip_25467 | chr1:41075218:41075451 | Frame-shift | rs61779183 | chr1:40558951:T:C | Distant downstream | 0.0206328436134219 | 0.0362122414288165 | LGG | Female-baised sQTL |
| exon_skip_25467 | chr1:41075218:41075451 | Frame-shift | rs12143100 | chr1:42043280:C:T | Distant upstream | 0.022126638198734 | 0.0429127623502472 | LGG | Female-baised sQTL |
| exon_skip_25467 | chr1:41075218:41075451 | Frame-shift | rs918259 | chr1:42050856:G:C | Distant upstream | 0.0230662794971085 | 0.0453687592323937 | LGG | Female-baised sQTL |
| exon_skip_25467 | chr1:41075218:41075451 | Frame-shift | rs72672744 | chr1:42053339:T:C | Distant upstream | 0.0230653211663805 | 0.0458111053363512 | LGG | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs7515159 | chr1:42008056:T:G | Distant upstream | -0.0546433202365043 | 0.0100039578013389 | COAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs4598479 | chr1:42010645:C:T | Distant upstream | -0.0546433202365043 | 0.0100039578013389 | COAD | Female-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs10437088 | chr1:42031717:C:A | Distant upstream | -0.0531104633653597 | 0.0156190632915706 | COAD | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs12745534 | chr1:41890579:G:C | Distant upstream | -0.0454663404350384 | 0.0496193432752846 | LUAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs1969213 | chr1:41772860:A:G | Distant upstream | -0.0340336482310337 | 0.00828477125366669 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs765039 | chr1:41774191:C:G | Distant upstream | -0.0340336482310337 | 0.00828477125366669 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs1877454 | chr1:41789823:C:T | Distant upstream | -0.0327035086736478 | 0.0234627720265151 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs1073926 | chr1:41795406:C:T | Distant upstream | -0.0323135204273242 | 0.0322547800954173 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs16828535 | chr1:41676802:G:A | Distant upstream | 0.0433296705177072 | 0.0355132429184247 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs4083592 | chr1:41633851:A:G | Distant upstream | 0.0343050286452743 | 0.0445504707574898 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs4660551 | chr1:41634308:T:C | Distant upstream | 0.0343050286452743 | 0.0445504707574898 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs11807117 | chr1:41635535:C:T | Distant upstream | 0.0343050286452743 | 0.0445504707574898 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs35988463 | chr1:41769260:C:T | Distant upstream | -0.0286952674062309 | 0.0489890167989341 | THCA | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs11803360 | chr1:40643265:G:C | Distant downstream | -0.0563698990169809 | 0.00794802714605618 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs11208590 | chr1:40642477:T:C | Distant downstream | -0.0504091692637858 | 0.016223856994757 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs349437 | chr1:41791455:A:G | Distant upstream | 0.0404992536489766 | 0.0309698264671721 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs349439 | chr1:41793337:G:T | Distant upstream | 0.0404992536489766 | 0.0309698264671721 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs7542025 | chr1:40643890:G:A | Distant downstream | -0.0416125458633449 | 0.0437115422882349 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs7520394 | chr1:40644197:C:T | Distant downstream | -0.0416125458633449 | 0.0437115422882349 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs1534955 | chr1:40642027:C:G | Distant downstream | -0.0493961028629664 | 0.0492661812422174 | COAD | Male-baised sQTL |
| exon_skip_25431 | chr1:41033982:41034048 | In-frame | rs913380 | chr1:40848686:A:T | Distant downstream | 0.0372893526312026 | 0.0285819363112124 | KIRP | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of SCMH1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000010803 | SCMH1 | C0004238 | Atrial Fibrillation | 2 | CTD_human |
| ENSG00000010803 | SCMH1 | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
| ENSG00000010803 | SCMH1 | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
| ENSG00000010803 | SCMH1 | C3468561 | familial atrial fibrillation | 2 | CTD_human |
