|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000008441 |
Summary for NFIX |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000008441 | Gene symbol | NFIX |
| Gene name | nuclear factor I X | |
| HGNC | 7788 | |
| Entrez ID | 4784 | |
| Gene type | protein_coding | |
| Synonyms | NFIX|NF1A | |
| UniProtAcc | Q14938 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for NFIX |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| NFIX | 1.08e+04 | -1.20e+00 | 2.58e-01 | -4.66e+00 | 3.16e-06 | 6.19e-05 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| NFIX | 1.03e+04 | -1.17e+00 | 2.89e-01 | -4.04e+00 | 5.29e-05 | 5.43e-04 | STAD |
Top |
Sex-biased somatic mutation for NFIX |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for NFIX |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 6.67e-01 | 8.33e-01 | -3.21e+00 | 1.32e-03 | 1.10e-02 | -1.67e-01 |
| GBM | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 4.66e-01 | 5.75e-01 | -2.14e+00 | 3.24e-02 | 4.32e-02 | -1.09e-01 |
| MESO | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 5.29e-01 | 6.30e-01 | -2.03e+00 | 4.22e-02 | 4.81e-02 | -1.02e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg02000253 | chr19:12996873 | CGI:chr19:12995770-12996874 | promoter,gene body | 4.92e-01 | 3.22e-01 | 3.67e+00 | 2.39e-04 | 1.07e-03 | 1.69e-01 |
| LUSC | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 6.92e-01 | 4.18e-01 | 4.12e+00 | 3.76e-05 | 5.31e-04 | 2.75e-01 |
| COAD | cg02000253 | chr19:12996873 | CGI:chr19:12995770-12996874 | promoter,gene body | 4.40e-01 | 3.26e-01 | 3.09e+00 | 2.00e-03 | 3.94e-03 | 1.15e-01 |
| COAD | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 7.97e-01 | 6.51e-01 | 4.89e+00 | 1.01e-06 | 1.20e-05 | 1.46e-01 |
| ESCA | cg02000253 | chr19:12996873 | CGI:chr19:12995770-12996874 | promoter,gene body | 4.07e-01 | 2.94e-01 | 2.48e+00 | 1.31e-02 | 3.74e-02 | 1.13e-01 |
| ESCA | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 6.98e-01 | 4.91e-01 | 2.78e+00 | 5.44e-03 | 3.46e-02 | 2.07e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg22630169 | chr19:12997403 | CGI:chr19:12995770-12996874 | promoter,gene body | 6.67e-01 | 4.12e-01 | 1.09e+01 | 9.74e-28 | 1.09e-26 | 2.55e-01 |
| KIRP | cg06197482 | chr19:12996438 | CGI:chr19:12995770-12996874 | promoter,gene body | 1.81e-01 | 7.92e-02 | 2.61e+00 | 9.00e-03 | 1.57e-02 | 1.02e-01 |
Top |
Exon skipping events with PSI in TCGA for NFIX |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| COAD | exon_skip_302779 | 8.97e-01 | 7.47e-01 | 5.78e+00 | 7.67e-09 | 3.08e-07 | 1.49e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| READ | exon_skip_302779 | 8.74e-01 | 6.92e-01 | 4.15e+00 | 3.28e-05 | 2.92e-03 | 1.81e-01 |
Top |
RNA A-to-I editing events in TCGA for NFIX |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for NFIX |
| TFs related to NFIX. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| NFIX related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
 |
Top |
Sex-biased RBP-ES network for NFIX |
| RBPs related to ES in NFIX. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| UVM | FMR1 | exon_skip_302777 | 6.36e+00 | 1.92e-03 | 6.81e+00 | 9.83e-01 | Female-biased |
| HNSC | RBM4 | exon_skip_302779 | 9.11e+00 | 1.23e-02 | 9.43e+00 | 9.85e-01 | Female-biased |
| HNSC | SAMD4A | exon_skip_302779 | 6.20e+00 | 1.18e-03 | 6.74e+00 | 9.83e-01 | Female-biased |
| NFIX related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs16981371 | chr19:16657382:G:A | - | 0.33051213532578 | 0.0111581254643877 | GBM | Female-baised eQTL |
| rs4926322 | chr19:13958271:C:T | - | 0.192273886899456 | 0.0288367458376038 | GBM | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12982990 | chr19:4894403:T:C | - | -0.0577538049003356 | 0.0122508638629836 | COAD | Male-baised eQTL |
| rs12983025 | chr19:4894442:T:C | - | -0.0577538049003356 | 0.0122508638629836 | COAD | Male-baised eQTL |
| rs2779172 | chr19:4897291:T:C | - | -0.0557186219058376 | 0.016188742892642 | COAD | Male-baised eQTL |
| rs11882393 | chr19:8531737:G:T | - | 0.0569644069533592 | 0.0402781475793862 | COAD | Male-baised eQTL |
| rs2967591 | chr19:8532744:T:C | - | 0.0559877129733628 | 0.0482707021622256 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg04646674 | |
| Position to Gene: gene | |
| Male Effect: -0.438810455254635 | |
| Female Effect: - | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg13338734 | |
| Position to Gene: gene | |
| Male Effect: -0.438810455254635 | |
| Female Effect: - | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg22630169 | |
| Position to Gene: gene,promoter | |
| Male Effect: - | |
| Female Effect: -0.35320833167393 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg04646674 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.35320833167393 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg13338734 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.435823076734731 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg05356319 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.435823076734731 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg06623668 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.435823076734731 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg24102622 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.411749844538698 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg22630169 | |
| Position to Gene: gene,promoter | |
| Male Effect: - | |
| Female Effect: -0.451103118046969 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg22983694 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.451103118046969 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg22824635 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.451103118046969 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg05356319 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.451103118046969 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg22630169 | |
| Position to Gene: gene,promoter | |
| Male Effect: - | |
| Female Effect: -0.423275540719684 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg22824635 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.423275540719684 | |
 | Gene ID: ENSG00000008441 |
| CpG Site: cg10157208 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.423275540719684 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg04646674 | chr19:13002668 | gene | -0.438810455254635 | 8.10815281450139e-07 | -0.6394127560773772 | 1.7275736457535306e-10 | LAML |
| cg13338734 | chr19:13002854 | gene | -0.438810455254635 | 8.10815281450139e-07 | -0.6394127560773772 | 1.7275736457535306e-10 | LAML |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg22630169 | chr19:12997403 | gene,promoter | -0.35320833167393 | 2.28442693785033e-08 | -0.3856879825232052 | 1.804464850450042e-10 | LUAD |
| cg04646674 | chr19:13002668 | gene | -0.35320833167393 | 2.28442693785033e-08 | -0.3856879825232052 | 1.804464850450042e-10 | LUAD |
| cg13338734 | chr19:13002854 | gene | -0.435823076734731 | 4.13749536790798e-06 | -0.3337792666708214 | 4.727634778634938e-08 | LUAD |
| cg05356319 | chr19:13011635 | gene | -0.435823076734731 | 4.13749536790798e-06 | -0.3337792666708214 | 4.727634778634938e-08 | LUAD |
| cg06623668 | chr19:13028002 | gene | -0.435823076734731 | 4.13749536790798e-06 | -0.3337792666708214 | 4.727634778634938e-08 | LUAD |
| cg24102622 | chr19:13013962 | gene | -0.411749844538698 | 1.3324979317844e-06 | -0.5227597082780162 | 7.714345849885688e-10 | LIHC |
| cg22630169 | chr19:12997403 | gene,promoter | -0.451103118046969 | 9.11311328829197e-24 | -0.7065174140856795 | 2.231780849395651e-28 | SKCM |
| cg22983694 | chr19:13000028 | gene,enhancer | -0.451103118046969 | 9.11311328829197e-24 | -0.7065174140856795 | 2.231780849395651e-28 | SKCM |
| cg22824635 | chr19:13001469 | gene | -0.451103118046969 | 9.11311328829197e-24 | -0.7065174140856795 | 2.231780849395651e-28 | SKCM |
| cg05356319 | chr19:13011635 | gene | -0.451103118046969 | 9.11311328829197e-24 | -0.7065174140856795 | 2.231780849395651e-28 | SKCM |
| cg22630169 | chr19:12997403 | gene,promoter | -0.423275540719684 | 8.832836189934e-15 | -0.6810642439349406 | 1.370720815025928e-19 | HNSC |
| cg22824635 | chr19:13001469 | gene | -0.423275540719684 | 8.832836189934e-15 | -0.6810642439349406 | 1.370720815025928e-19 | HNSC |
| cg10157208 | chr19:13001635 | gene | -0.423275540719684 | 8.832836189934e-15 | -0.6810642439349406 | 1.370720815025928e-19 | HNSC |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs11669811 | chr19:13388231:G:T | Distant downstream | 0.0308677941551181 | 0.00607279304497416 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs2035278 | chr19:13335028:G:A | Distant downstream | -0.0300222552590062 | 0.0118852892732563 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs2419549 | chr19:13383445:G:A | Distant downstream | 0.0307565715944198 | 0.0122947147185101 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10408012 | chr19:13340288:T:C | Distant downstream | -0.0340850047830089 | 0.0127140061460055 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10424440 | chr19:13345554:T:C | Distant downstream | -0.0335957290920749 | 0.0170961820750599 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7257076 | chr19:13341565:T:C | Distant downstream | -0.0307216457322256 | 0.0187166943468234 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7253483 | chr19:13341736:C:T | Distant downstream | -0.0307216457322256 | 0.0187166943468234 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs11670018 | chr19:13373100:T:C | Distant downstream | 0.0305996543329556 | 0.0194902156141677 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926269 | chr19:13337644:T:C | Distant downstream | -0.0299744278228629 | 0.0214955531308716 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926274 | chr19:13343925:C:T | Distant downstream | -0.0328181469680603 | 0.0215314066656455 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs2248069 | chr19:13334394:C:T | Distant downstream | -0.0296180850896293 | 0.0231192602014695 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs34296137 | chr19:13334759:G:A | Distant downstream | -0.0291666122774919 | 0.0250132384464425 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs12459092 | chr19:13336564:G:A | Distant downstream | -0.0297213947924032 | 0.0251317740185611 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926268 | chr19:13337282:A:G | Distant downstream | -0.0297213947924032 | 0.0251317740185611 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926270 | chr19:13337652:A:G | Distant downstream | -0.0297213947924032 | 0.0251317740185611 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10414327 | chr19:13340807:T:C | Distant downstream | -0.030070915167793 | 0.0256863615391518 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs11670927 | chr19:13388419:C:G | Distant downstream | 0.0290241116045558 | 0.0258885513028475 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926152 | chr19:13337697:T:C | Distant downstream | -0.0296299895772949 | 0.0264001717167061 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10426253 | chr19:13339133:T:A | Distant downstream | -0.0299698503588814 | 0.026633041244846 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10420663 | chr19:13339134:A:G | Distant downstream | -0.0299698503588814 | 0.026633041244846 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs2900915 | chr19:13337113:A:G | Distant downstream | -0.0293715335179548 | 0.0273648073459275 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926151 | chr19:13337465:G:A | Distant downstream | -0.0293715335179548 | 0.0273648073459275 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10419230 | chr19:13338830:C:T | Distant downstream | -0.0295321988298474 | 0.029919488451183 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10419917 | chr19:13339118:C:T | Distant downstream | -0.0295321988298474 | 0.029919488451183 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs12460484 | chr19:13338602:C:T | Distant downstream | -0.0284549107487498 | 0.0316294322163091 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs3816720 | chr19:13336152:T:C | Distant downstream | -0.0291692457545234 | 0.0318988139446708 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926273 | chr19:13338208:T:C | Distant downstream | -0.0295963630664099 | 0.0333011705489152 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926271 | chr19:13337865:A:G | Distant downstream | -0.0295332161667383 | 0.0338155247292367 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926153 | chr19:13337963:C:T | Distant downstream | -0.0295332161667383 | 0.0338155247292367 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10417607 | chr19:13336356:T:C | Distant downstream | -0.0288342891111304 | 0.0343364817728527 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs16008 | chr19:13332956:T:C | Distant downstream | -0.0318088803721817 | 0.0350774143663042 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926267 | chr19:13333458:A:G | Distant downstream | -0.0286248929721284 | 0.0356008075355842 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs2306348 | chr19:13334330:C:T | Distant downstream | -0.0284799217229374 | 0.036356207345797 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs11085845 | chr19:13373389:A:T | Distant downstream | 0.0286915626937279 | 0.0370340290920235 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7256928 | chr19:13341461:T:C | Distant downstream | -0.0253845806594523 | 0.0403051720739466 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926149 | chr19:13334060:C:T | Distant downstream | -0.0281704763944133 | 0.0440946708823928 | LUAD | Female-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs4926150 | chr19:13334077:C:G | Distant downstream | -0.0281704763944133 | 0.0440946708823928 | LUAD | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7253138 | chr19:13438454:G:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7252635 | chr19:13442128:C:T | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs74258419 | chr19:13444402:G:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7253463 | chr19:13445983:G:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7258389 | chr19:13446090:T:G | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs7253717 | chr19:13446152:G:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs79950997 | chr19:13448465:A:G | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs11878757 | chr19:13450100:C:T | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs3764615 | chr19:13453138:C:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs58070391 | chr19:13453188:G:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs77994482 | chr19:13453665:G:A | Distant downstream | -0.0466048685785121 | 0.04030714724092 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs2419718 | chr19:13458417:C:T | Distant downstream | -0.0470001234323399 | 0.0426884888651763 | THCA | Male-baised sQTL |
| exon_skip_302779 | chr19:13078612:13078735 | In-frame | rs10412878 | chr19:13345168:A:T | Distant downstream | 0.040654823842312 | 0.00472717049743866 | LUSC | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of NFIX |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000008441 | NFIX | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| ENSG00000008441 | NFIX | C0265211 | Marshall-Smith syndrome | 1 | CTD_human |
