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Gene: ENSG00000002933 |
Summary for TMEM176A |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000002933 | Gene symbol | TMEM176A |
| Gene name | transmembrane protein 176A | |
| HGNC | 24930 | |
| Entrez ID | 55365 | |
| Gene type | protein_coding | |
| Synonyms | TMEM176A|HCA112|MS4B1 | |
| UniProtAcc | Q96HP8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TMEM176A |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TMEM176A | 3.80e+03 | 1.10e+00 | 2.51e-01 | 4.37e+00 | 1.25e-05 | 3.74e-05 | LUAD |
| TMEM176A | 1.22e+03 | 1.49e+00 | 3.24e-01 | 4.60e+00 | 4.30e-06 | 2.13e-05 | THCA |
| TMEM176A | 2.79e+04 | 1.13e+00 | 2.37e-01 | 4.77e+00 | 1.81e-06 | 6.15e-06 | KIRP |
| TMEM176A | 1.85e+04 | -3.36e+00 | 4.86e-01 | -6.90e+00 | 5.13e-12 | 1.16e-10 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
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Sex-biased somatic mutation for TMEM176A |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for TMEM176A |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter | 2.37e-01 | 3.66e-01 | -2.06e+00 | 3.98e-02 | 4.59e-02 | -1.29e-01 |
| ESCA | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter | 4.55e-01 | 3.43e-01 | 2.14e+00 | 3.21e-02 | 4.47e-02 | 1.12e-01 |
| ESCA | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | promoter | 5.51e-01 | 4.34e-01 | 2.12e+00 | 3.37e-02 | 4.53e-02 | 1.17e-01 |
| ESCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter | 3.61e-01 | 2.61e-01 | 2.52e+00 | 1.17e-02 | 2.91e-02 | 1.00e-01 |
| ACC | cg05726600 | chr7:150801506 | CGI:chr7:150799721-150801118 | promoter,gene body | 6.12e-01 | 7.38e-01 | -2.47e+00 | 1.35e-02 | 2.98e-02 | -1.26e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg05726600 | chr7:150801506 | CGI:chr7:150799721-150801118 | promoter,gene body | 1.60e-01 | 2.94e-01 | -5.35e+00 | 8.62e-08 | 4.40e-07 | -1.35e-01 |
| HNSC | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter,exon,gene body | 5.90e-01 | 8.01e-01 | -4.71e+00 | 2.46e-06 | 1.20e-05 | -2.11e-01 |
| LUSC | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter | 4.17e-01 | 1.34e-01 | 3.53e+00 | 4.19e-04 | 1.49e-03 | 2.83e-01 |
| LUSC | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | promoter | 4.66e-01 | 2.22e-01 | 3.61e+00 | 3.09e-04 | 1.24e-03 | 2.43e-01 |
| LUSC | cg26385222 | chr7:150799989 | CGI:chr7:150799721-150801118 | promoter | 4.68e-01 | 2.49e-01 | 3.59e+00 | 3.32e-04 | 1.29e-03 | 2.19e-01 |
| LUSC | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter | 2.20e-01 | 1.06e-01 | 3.26e+00 | 1.12e-03 | 2.80e-03 | 1.14e-01 |
| LUSC | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter,exon,gene body | 6.43e-01 | 8.62e-01 | -3.14e+00 | 1.71e-03 | 3.74e-03 | -2.19e-01 |
| BLCA | cg04861380 | chr7:150800575 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 1.99e-01 | 2.41e-02 | 3.11e+00 | 1.88e-03 | 3.73e-03 | 1.75e-01 |
| BLCA | cg19336959 | chr7:150800615 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 2.05e-01 | 3.07e-02 | 3.00e+00 | 2.66e-03 | 4.92e-03 | 1.74e-01 |
| BLCA | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter | 4.07e-01 | 2.16e-01 | 2.06e+00 | 3.92e-02 | 4.14e-02 | 1.92e-01 |
| BLCA | cg26385222 | chr7:150799989 | CGI:chr7:150799721-150801118 | promoter | 4.61e-01 | 3.13e-01 | 2.59e+00 | 9.47e-03 | 1.35e-02 | 1.48e-01 |
| BLCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter | 3.34e-01 | 1.26e-01 | 3.33e+00 | 8.61e-04 | 2.02e-03 | 2.08e-01 |
| BLCA | cg25124476 | chr7:150800650 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 2.53e-01 | 9.46e-02 | 2.98e+00 | 2.90e-03 | 5.27e-03 | 1.58e-01 |
| BLCA | cg00417408 | chr7:150800652 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 2.74e-01 | 1.14e-01 | 2.89e+00 | 3.82e-03 | 6.57e-03 | 1.61e-01 |
| BLCA | cg07769074 | chr7:150800672 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 1.68e-01 | 5.79e-02 | 2.63e+00 | 8.49e-03 | 1.24e-02 | 1.10e-01 |
| BLCA | cg08359956 | chr7:150801117 | CGI:chr7:150799721-150801118 | promoter,gene body | 3.25e-01 | 1.93e-01 | 2.18e+00 | 2.94e-02 | 3.31e-02 | 1.32e-01 |
| CHOL | cg08359956 | chr7:150801117 | CGI:chr7:150799721-150801118 | promoter,gene body | 3.81e-01 | 1.29e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 2.52e-01 |
| CHOL | cg03964111 | chr7:150801405 | CGI:chr7:150799721-150801118 | promoter,gene body | 5.08e-01 | 2.10e-01 | 2.29e+00 | 2.23e-02 | 3.24e-02 | 2.97e-01 |
| CHOL | cg10409299 | chr7:150801755 | CGI:chr7:150799721-150801118 | promoter,exon,gene body | 7.43e-01 | 5.04e-01 | 3.10e+00 | 1.96e-03 | 1.07e-02 | 2.40e-01 |
| CHOL | cg07208344 | chr7:150802274 | CGI:chr7:150799721-150801118 | promoter,exon,CDS,gene body | 8.51e-01 | 6.09e-01 | 3.54e+00 | 4.02e-04 | 8.32e-03 | 2.42e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg04861380 | chr7:150800575 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 1.51e-01 | 2.28e-02 | 9.05e+00 | 1.48e-19 | 7.69e-19 | 1.29e-01 |
| BRCA | cg05017199 | chr7:150799977 | CGI:chr7:150799721-150801118 | promoter | 2.87e-01 | 9.07e-02 | 8.44e+00 | 3.14e-17 | 1.36e-16 | 1.96e-01 |
| BRCA | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | promoter | 4.01e-01 | 1.86e-01 | 8.77e+00 | 1.85e-18 | 8.80e-18 | 2.15e-01 |
| BRCA | cg26385222 | chr7:150799989 | CGI:chr7:150799721-150801118 | promoter | 3.55e-01 | 2.04e-01 | 7.62e+00 | 2.59e-14 | 8.95e-14 | 1.52e-01 |
| BRCA | cg02244695 | chr7:150800258 | CGI:chr7:150799721-150801118 | promoter | 2.37e-01 | 1.05e-01 | 6.93e+00 | 4.36e-12 | 1.27e-11 | 1.32e-01 |
| BRCA | cg25124476 | chr7:150800650 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 1.99e-01 | 8.56e-02 | 6.46e+00 | 1.04e-10 | 2.72e-10 | 1.13e-01 |
| BRCA | cg00417408 | chr7:150800652 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 2.14e-01 | 9.44e-02 | 7.02e+00 | 2.26e-12 | 6.74e-12 | 1.20e-01 |
| BRCA | cg08359956 | chr7:150801117 | CGI:chr7:150799721-150801118 | promoter,gene body | 4.09e-01 | 3.04e-01 | 6.01e+00 | 1.84e-09 | 4.37e-09 | 1.05e-01 |
| BRCA | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter,exon,gene body | 7.66e-01 | 9.16e-01 | -8.93e+00 | 4.30e-19 | 2.16e-18 | -1.50e-01 |
| LUAD | cg19336959 | chr7:150800615 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 1.28e-01 | 2.49e-02 | 3.36e+00 | 7.93e-04 | 2.75e-03 | 1.03e-01 |
| LUAD | cg00417408 | chr7:150800652 | CGI:chr7:150799721-150801118 | UTR,promoter,exon,gene body | 2.02e-01 | 8.64e-02 | 3.11e+00 | 1.90e-03 | 4.92e-03 | 1.15e-01 |
| LIHC | cg13459303 | chr7:150802188 | CGI:chr7:150799721-150801118 | promoter,exon,gene body | 6.06e-01 | 4.88e-01 | 2.10e+00 | 3.61e-02 | 3.86e-02 | 1.17e-01 |
| KIRP | cg14991769 | chr7:150800069 | CGI:chr7:150799721-150801118 | promoter | 2.04e-01 | 6.44e-02 | 2.87e+00 | 4.17e-03 | 9.48e-03 | 1.40e-01 |
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Exon skipping events with PSI in TCGA for TMEM176A |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| LUAD | exon_skip_472360 | 6.77e-01 | 7.82e-01 | -3.76e+00 | 1.72e-04 | 7.60e-04 | -1.05e-01 |
| CHOL | exon_skip_472360 | 7.54e-01 | 9.06e-01 | -2.41e+00 | 1.58e-02 | 2.87e-02 | -1.52e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| KIRP | exon_skip_472360 | 7.69e-01 | 8.79e-01 | -3.38e+00 | 7.22e-04 | 6.99e-03 | -1.10e-01 |
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RNA A-to-I editing events in TCGA for TMEM176A |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for TMEM176A |
| TFs related to TMEM176A. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PCPG | PLAGL2 | TMEM176A | 3.48e+00 | 9.30e-03 | 4.30e+00 | 9.82e-01 | Female-biased |
| TMEM176A related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for TMEM176A |
| RBPs related to ES in TMEM176A. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SKCM | ZC3H10 | exon_skip_472345 | 7.10e+00 | 2.64e-03 | 7.60e+00 | 9.88e-01 | Female-biased |
| SARC | BRUNOL6 | exon_skip_472345 | 6.61e+00 | 5.73e-03 | 7.03e+00 | 9.81e-01 | Female-biased |
| SARC | ZC3H10 | exon_skip_472345 | 7.13e+00 | 2.37e-03 | 7.65e+00 | 9.88e-01 | Female-biased |
| TMEM176A related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2240986 | chr7:157409380:C:T | - | 0.200792843688623 | 0.044879527021699 | GBM | Female-baised eQTL |
| rs714429 | chr7:144456641:T:C | - | 0.112143034012101 | 0.0157648462853003 | STAD | Female-baised eQTL |
| rs2888075 | chr7:144456786:G:A | - | 0.105916902029832 | 0.029265647205511 | STAD | Female-baised eQTL |
| rs62483108 | chr7:144442326:G:A | - | 0.109309422125943 | 0.032004604486872 | STAD | Female-baised eQTL |
| rs6962238 | chr7:152642023:C:G | - | -0.112789357827102 | 0.0148246217002099 | LGG | Female-baised eQTL |
| rs13242554 | chr7:152642608:G:A | - | -0.112789357827102 | 0.0148246217002099 | LGG | Female-baised eQTL |
| rs10272702 | chr7:143261090:T:C | - | 0.217727410020367 | 0.000956594422757552 | BLCA | Female-baised eQTL |
| rs116131242 | chr7:147943620:T:G | - | 0.32173155047427 | 0.00120856458205534 | BLCA | Female-baised eQTL |
| rs79051424 | chr7:147945441:C:T | - | 0.32173155047427 | 0.00120856458205534 | BLCA | Female-baised eQTL |
| rs114515860 | chr7:147946074:G:A | - | 0.32173155047427 | 0.00120856458205534 | BLCA | Female-baised eQTL |
| rs117609483 | chr7:147945736:A:T | - | 0.299026255902436 | 0.0024701532562307 | BLCA | Female-baised eQTL |
| rs76633493 | chr7:147947037:C:T | - | 0.299026255902436 | 0.0024701532562307 | BLCA | Female-baised eQTL |
| rs77187521 | chr7:147948068:A:G | - | 0.299026255902436 | 0.0024701532562307 | BLCA | Female-baised eQTL |
| rs77689119 | chr7:155898541:A:G | - | 0.245354825008258 | 0.0141530899549403 | BLCA | Female-baised eQTL |
| rs79567485 | chr7:155893852:C:A | - | 0.244956849244873 | 0.0147125259046715 | BLCA | Female-baised eQTL |
| rs55810549 | chr7:155895855:C:T | - | 0.244956849244873 | 0.0147125259046715 | BLCA | Female-baised eQTL |
| rs74454984 | chr7:155901136:C:A | - | 0.244024542045296 | 0.0151239168663698 | BLCA | Female-baised eQTL |
| rs140991464 | chr7:155902087:C:T | - | 0.244024542045296 | 0.0151239168663698 | BLCA | Female-baised eQTL |
| rs55639312 | chr7:155903662:G:T | - | 0.244024542045296 | 0.0151239168663698 | BLCA | Female-baised eQTL |
| rs74765187 | chr7:155904568:A:T | - | 0.244024542045296 | 0.0151239168663698 | BLCA | Female-baised eQTL |
| rs56023813 | chr7:155905671:C:T | - | 0.243189451102771 | 0.0162794127472555 | BLCA | Female-baised eQTL |
| rs2966504 | chr7:152797101:A:T | - | 0.085312218445669 | 0.0310298122507872 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs28539822 | chr7:146098902:C:T | - | 0.0827797969311557 | 0.0375391685387494 | LGG | Male-baised eQTL |
| rs2692380 | chr7:144925589:C:T | - | -0.0900562695732959 | 0.0105839637575415 | KIRC | Male-baised eQTL |
| rs173168 | chr7:146677431:A:G | - | 0.108726838154445 | 0.0288841656674702 | KIRC | Male-baised eQTL |
| rs116135912 | chr7:146674514:A:T | - | 0.108512136273921 | 0.0295288332983519 | KIRC | Male-baised eQTL |
| rs1353235 | chr7:146675932:T:C | - | 0.108512136273921 | 0.0295288332983519 | KIRC | Male-baised eQTL |
| rs66533253 | chr7:146676484:C:T | - | 0.108512136273921 | 0.0295288332983519 | KIRC | Male-baised eQTL |
| rs2699472 | chr7:144925399:T:A | - | -0.0781568697413748 | 0.0342307656441365 | KIRC | Male-baised eQTL |
| rs2699467 | chr7:144924602:T:C | - | -0.0797950830625421 | 0.0358493070794381 | KIRC | Male-baised eQTL |
| rs200671290 | chr7:159243971:T:G | - | 0.0850290106981579 | 0.0360583547773389 | LUAD | Male-baised eQTL |
| rs883839 | chr7:145046312:A:C | - | 0.0663025273654478 | 0.0169767969661514 | COAD | Male-baised eQTL |
| rs11981103 | chr7:141272843:C:T | - | 0.0510013653546972 | 0.0259882947646189 | COAD | Male-baised eQTL |
| rs34908063 | chr7:145052378:C:T | - | 0.0645124465124806 | 0.0286308839951279 | COAD | Male-baised eQTL |
| rs216994 | chr7:141260207:G:A | - | -0.0495911932001274 | 0.0289359673564039 | COAD | Male-baised eQTL |
| rs891512 | chr7:151011001:A:G | - | -0.0594755469293117 | 0.0293494773969265 | COAD | Male-baised eQTL |
| rs12539896 | chr7:141244886:C:T | - | 0.0496080718936023 | 0.0402831032869007 | COAD | Male-baised eQTL |
| rs216996 | chr7:141270582:C:A | - | -0.0477656149720622 | 0.0414083183107322 | COAD | Male-baised eQTL |
| rs10488316 | chr7:154399115:C:G | - | -0.0844227157169372 | 0.0445336039641023 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000002933 |
| CpG Site: cg10409299 | |
| Position to Gene: gene,exon,promoter | |
| Male Effect: -0.328274994051129 | |
| Female Effect: - | |
 | Gene ID: ENSG00000002933 |
| CpG Site: cg10409299 | |
| Position to Gene: gene,exon,promoter | |
| Male Effect: - | |
| Female Effect: -0.451537921347272 | |
 | Gene ID: ENSG00000002933 |
| CpG Site: cg05726600 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.262855728683552 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10409299 | chr7:150801755 | gene,exon,promoter | -0.328274994051129 | 1.09281057206577e-10 | -0.6555306586117758 | 2.3966068786781775e-13 | PAAD |
| cg05726600 | chr7:150801506 | gene,promoter | -0.262855728683552 | 1.21890720289222e-15 | -0.47347043072197115 | 1.4908524883825923e-17 | LGG |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10409299 | chr7:150801755 | gene,exon,promoter | -0.451537921347272 | 4.90121926994426e-14 | -0.5041357501789371 | 7.633855723943979e-18 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TMEM176A |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
