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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Kcnb2 (spascer ID:98741)

Gene summary for Kcnb2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Kcnb2

Gene ID

98741

Gene namepotassium voltage gated channel, Shab-related subfamily, member 2
Synonyms9630047L19Rik|BB130875|Kv2.2
Cytomap1 A3|1 4.5 cM
Type of geneprotein-coding
Descriptionpotassium voltage-gated channel subfamily B member 2voltage-gated potassium channel subunit Kv2.2
Modification date20220424
UniProtAcc

A6H8H5


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Kcnb2

GO:0005249

voltage-gated potassium channel activity

21873635

Function
Kcnb2

GO:0005251

delayed rectifier potassium channel activity

21873635

Function
Kcnb2

GO:0008076

voltage-gated potassium channel complex

21873635

Component
Kcnb2

GO:0016021

integral component of membrane

21873635

Component
Kcnb2

GO:0030425

dendrite

21873635

Component
Kcnb2

GO:0043025

neuronal cell body

21873635

Component
Kcnb2

GO:0071805

potassium ion transmembrane transport

21873635

Process

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Spatial pattern events for Kcnb2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Kcnb2MouseBrainS2 344135153.60e-10
Kcnb2MouseBrainS3 344135153.88e-13
Kcnb2MouseBrainS6 344135155.31e-06
Kcnb2MouseBrainS7 344135156.45e-10
Kcnb2MouseBrainrep_4 351413744.55e-06
Kcnb2MouseEmbryo1D 342108879.68e-09
Kcnb2MouseEmbryo1E 342108875.40e-10
Kcnb2MouseEmbryo1F 342108872.30e-14
Kcnb2MouseEmbryo1G 342108877.09e-08
Kcnb2MouseEmbryo2G 342108871.06e-14
Kcnb2MouseEmbryo2H 342108871.92e-13
Kcnb2MouseEmbryo3D 342108878.93e-15
Kcnb2MouseEmbryo3F 342108875.82e-15
Kcnb2MouseEmbryo3G 342108876.10e-12
Kcnb2MouseEmbryo4C 342108872.72e-07
Kcnb2MouseEmbryo4D 342108877.75e-15
Kcnb2MouseEmbryo4E 342108874.53e-15
Kcnb2MouseBrainrep_1 350277291.55e-11
Kcnb2MouseBrainrep_2 350277292.83e-15
Kcnb2MouseBrainrep_3 350277291.32e-15
Kcnb2MouseBrainrep_4 350277293.26e-08
Kcnb2MouseBrainrep_5 350277291.24e-11
Kcnb2MouseBrainOFB_ad_rep1 330837251.44e-03
Kcnb2MouseBrainOFB_ad_rep2 330837251.88e-05
Kcnb2MouseBrainOFB_ad_rep3 330837252.51e-05
Kcnb2MouseBrainOFB_ad_rep4 330837251.52e-04
Kcnb2MouseBrainOFB_ad_rep5 330837251.76e-04
Kcnb2MouseBrainOFB_ad_rep6 330837256.68e-04
Kcnb2MouseBrainOFB_adpolb_rep1 330837251.21e-05
Kcnb2MouseBrainOFB_adpolb_rep2 330837251.32e-06
Kcnb2MouseBrainOFB_adpolb_rep3 330837259.17e-11
Kcnb2MouseBrainOFB_adpolb_rep4 330837252.60e-11
Kcnb2MouseBrainOFB_adpolb_rep6 330837253.29e-03
Kcnb2MouseBrainOFB_polb_rep5 330837251.02e-07
Kcnb2MouseBrainOFB_polb_rep6 330837251.00e-03
Kcnb2MouseBrainOFB_wt_rep3 330837252.88e-03
Kcnb2MouseBrainOFB_wt_rep4 330837253.77e-07
Kcnb2MouseBrainOFB_wt_rep5 330837254.24e-05
Kcnb2MouseBrainOFB_wt_rep6 330837259.73e-07

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_4_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_OFB_ad_rep1_H&E
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Brain_OFB_ad_rep2_H&E
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Brain_OFB_ad_rep3_H&E
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Brain_OFB_ad_rep4_H&E
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Brain_OFB_ad_rep5_H&E
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Brain_OFB_ad_rep6_H&E
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Brain_OFB_adpolb_rep1_H&E
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Brain_OFB_adpolb_rep2_H&E
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Brain_OFB_adpolb_rep3_H&E
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Brain_OFB_adpolb_rep4_H&E
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Brain_OFB_adpolb_rep6_H&E
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Brain_OFB_polb_rep5_H&E
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Brain_OFB_polb_rep6_H&E
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Brain_OFB_wt_rep3_H&E
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Brain_OFB_wt_rep4_H&E
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Brain_OFB_wt_rep5_H&E
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Brain_OFB_wt_rep6_H&E
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Spatial pattern pathway has Kcnb2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Kcnb2GOBP_Cation_TransportMouseSpinal cordCN94_E1 5.8e-06
Kcnb2GOBP_Protein_Localization_To_Cell_PeripheryMouseSpinal cordCN94_E1 4.3e-06
Kcnb2GOBP_Protein_Localization_To_Plasma_MembraneMouseSpinal cordCN94_E1 8.0e-06
Kcnb2GOBP_Regulation_Of_TransportMouseSpinal cordCN94_E1 5.3e-07
Kcnb2GOBP_Cation_Transmembrane_TransportMouseSpinal cordL7CN45_C1 1.3e-08
Kcnb2GOBP_Cellular_Macromolecule_LocalizationMouseSpinal cordL7CN45_C1 4.2e-07
Kcnb2GOBP_Inorganic_Ion_Transmembrane_TransportMouseSpinal cordL7CN45_C1 6.6e-07
Kcnb2GOBP_Potassium_Ion_TransportMouseSpinal cordL7CN45_C1 9.1e-09
Kcnb2GOBP_Protein_Complex_OligomerizationMouseSpinal cordL7CN45_C1 1.1e-06
Kcnb2GOBP_Protein_HomooligomerizationMouseSpinal cordL7CN45_C1 5.1e-08
Kcnb2GOBP_Regulation_Of_Ion_TransportMouseSpinal cordL7CN45_C1 3.6e-07
Kcnb2GOBP_Regulation_Of_Transmembrane_TransportMouseSpinal cordL7CN45_C1 8.8e-08
Kcnb2GOBP_Transmembrane_TransportMouseSpinal cordL7CN45_C1 3.5e-08
Kcnb2GOBP_Regulation_Of_Muscle_System_ProcessMouseSpinal cordL7CN47_C1 3.9e-06
Kcnb2GOBP_Regulation_Of_Smooth_Muscle_ContractionMouseSpinal cordL7CN60_D1 3.3e-06
Kcnb2GOBP_Regulation_Of_System_ProcessMouseSpinal cordL8CN17_E1 7.2e-06
Kcnb2GOBP_Cation_Transmembrane_TransportMouseBrainrep_1 4.4e-30
Kcnb2GOBP_Cation_TransportMouseBrainrep_1 1.5e-22
Kcnb2GOBP_Inorganic_Ion_Transmembrane_TransportMouseBrainrep_1 8.6e-24
Kcnb2GOBP_Muscle_ContractionMouseBrainrep_1 6.0e-18
Kcnb2GOBP_Muscle_System_ProcessMouseBrainrep_1 8.3e-21
Kcnb2GOBP_Potassium_Ion_TransportMouseBrainrep_1 3.5e-56
Kcnb2GOBP_Protein_Complex_OligomerizationMouseBrainrep_1 8.5e-20
Kcnb2GOBP_Protein_HomooligomerizationMouseBrainrep_1 1.2e-17
Kcnb2GOBP_Protein_Localization_To_Cell_PeripheryMouseBrainrep_1 8.2e-32
Kcnb2GOBP_Protein_Localization_To_Plasma_MembraneMouseBrainrep_1 1.5e-07
Kcnb2GOBP_Regulation_Of_Ion_TransportMouseBrainrep_1 8.9e-34
Kcnb2GOBP_Regulation_Of_Muscle_System_ProcessMouseBrainrep_1 1.4e-15
Kcnb2GOBP_Regulation_Of_System_ProcessMouseBrainrep_1 4.2e-15
Kcnb2GOBP_Regulation_Of_Transmembrane_TransportMouseBrainrep_1 1.4e-17
Kcnb2GOBP_Regulation_Of_TransportMouseBrainrep_1 3.9e-15
Kcnb2GOBP_Transmembrane_TransportMouseBrainrep_1 3.1e-23
Kcnb2GOBP_Cellular_Macromolecule_LocalizationMouseBrainrep_31.6e-125
Kcnb2GOBP_Regulation_Of_Muscle_ContractionMouseBrainrep_3 1.3e-13
Kcnb2GOBP_Muscle_ContractionMouseEmbryorep_14 1.7e-07
Kcnb2GOBP_Protein_Complex_OligomerizationMouseEmbryorep_14 9.3e-21
Kcnb2GOBP_Protein_HomooligomerizationMouseEmbryorep_14 4.9e-14
Kcnb2GOBP_Regulation_Of_Muscle_ContractionMouseEmbryorep_14 4.2e-30
Kcnb2GOBP_Regulation_Of_Muscle_System_ProcessMouseEmbryorep_14 3.8e-13
Kcnb2GOBP_Regulation_Of_Smooth_Muscle_ContractionMouseEmbryorep_14 1.1e-57
Kcnb2GOBP_Smooth_Muscle_ContractionMouseEmbryorep_14 2.6e-47
Kcnb2GOBP_Cellular_Macromolecule_LocalizationMouseEmbryorep_2 5.5e-15
Kcnb2GOBP_Protein_Complex_OligomerizationMouseEmbryorep_31.5e-141
Kcnb2GOBP_Regulation_Of_Transmembrane_TransportMouseKidneyNep 4.2e-26
Kcnb2GOBP_Regulation_Of_TransportMouseKidneyNep 2.6e-47
Kcnb2GOBP_Transmembrane_TransportMouseKidneyNep 4.2e-26
Kcnb2GOBP_Cation_Transmembrane_TransportMouseKidneyrep_2 7.3e-17
Kcnb2GOBP_Cation_TransportMouseKidneyrep_2 5.9e-23
Kcnb2GOBP_Cellular_Macromolecule_LocalizationMouseKidneyrep_2 3.5e-61
Kcnb2GOBP_Inorganic_Ion_Transmembrane_TransportMouseKidneyrep_2 2.4e-15
Kcnb2GOBP_Muscle_ContractionMouseKidneyrep_2 1.1e-89
Kcnb2GOBP_Muscle_System_ProcessMouseKidneyrep_2 1.2e-86
Kcnb2GOBP_Potassium_Ion_TransportMouseKidneyrep_2 2.8e-73
Kcnb2GOBP_Protein_Complex_OligomerizationMouseKidneyrep_2 2.8e-82
Kcnb2GOBP_Protein_HomooligomerizationMouseKidneyrep_2 3.3e-85
Kcnb2GOBP_Protein_Localization_To_Cell_PeripheryMouseKidneyrep_2 1.0e-86
Kcnb2GOBP_Protein_Localization_To_Plasma_MembraneMouseKidneyrep_2 6.5e-83
Kcnb2GOBP_Regulation_Of_Ion_TransportMouseKidneyrep_25.5e-106
Kcnb2GOBP_Regulation_Of_Muscle_ContractionMouseKidneyrep_2 1.7e-95
Kcnb2GOBP_Regulation_Of_Muscle_System_ProcessMouseKidneyrep_24.8e-103
Kcnb2GOBP_Regulation_Of_Smooth_Muscle_ContractionMouseKidneyrep_2 1.3e-57
Kcnb2GOBP_Regulation_Of_System_ProcessMouseKidneyrep_2 3.2e-62
Kcnb2GOBP_Regulation_Of_Transmembrane_TransportMouseKidneyrep_22.0e-115
Kcnb2GOBP_Regulation_Of_TransportMouseKidneyrep_2 2.4e-58
Kcnb2GOBP_Smooth_Muscle_ContractionMouseKidneyrep_2 7.0e-80
Kcnb2GOBP_Transmembrane_TransportMouseKidneyrep_2 2.7e-23
Kcnb2GOBP_Regulation_Of_Smooth_Muscle_ContractionMouseLiverCN16-E1 9.4e-12
Kcnb2GOBP_Smooth_Muscle_ContractionMouseLiverCN16-E1 1.8e-09
Kcnb2GOBP_Regulation_Of_TransportMouseLiverCN73-C1 1.8e-07
Kcnb2GOBP_Cation_Transmembrane_TransportMouseLiverrep_15 8.9e-14
Kcnb2GOBP_Inorganic_Ion_Transmembrane_TransportMouseLiverrep_15 2.4e-07
Kcnb2GOBP_Muscle_System_ProcessMouseLiverrep_15 9.3e-22
Kcnb2GOBP_Regulation_Of_Muscle_System_ProcessMouseLiverrep_15 2.7e-29
Kcnb2GOBP_Regulation_Of_Smooth_Muscle_ContractionMouseLiverrep_15 2.0e-12
Kcnb2GOBP_Cation_TransportMouseLiverrep_16 1.2e-18
Kcnb2GOBP_Potassium_Ion_TransportMouseLiverrep_16 3.8e-11
Kcnb2GOBP_Smooth_Muscle_ContractionMouseLiverrep_16 8.9e-11
Kcnb2GOBP_Transmembrane_TransportMouseLiverrep_16 1.4e-13
Kcnb2GOBP_Cellular_Macromolecule_LocalizationMouseLymphMS-1 1.1e-11
Kcnb2GOBP_Muscle_ContractionMouseLymphMS-1 3.4e-09
Kcnb2GOBP_Muscle_System_ProcessMouseLymphMS-1 1.6e-08
Kcnb2GOBP_Potassium_Ion_TransportMouseLymphMS-1 3.6e-10
Kcnb2GOBP_Protein_Complex_OligomerizationMouseLymphMS-1 2.9e-20
Kcnb2GOBP_Protein_HomooligomerizationMouseLymphMS-1 1.2e-10
Kcnb2GOBP_Protein_Localization_To_Cell_PeripheryMouseLymphMS-1 8.7e-09
Kcnb2GOBP_Protein_Localization_To_Plasma_MembraneMouseLymphMS-1 3.6e-07
Kcnb2GOBP_Regulation_Of_Ion_TransportMouseLymphMS-1 1.5e-09
Kcnb2GOBP_Regulation_Of_System_ProcessMouseLymphMS-1 1.8e-07
Kcnb2GOBP_Regulation_Of_Transmembrane_TransportMouseLymphMS-1 3.3e-13
Kcnb2GOBP_Regulation_Of_TransportMouseLymphMS-1 1.4e-12
Kcnb2GOBP_Smooth_Muscle_ContractionMouseLymphMS-1 2.5e-10
Kcnb2GOBP_Regulation_Of_Smooth_Muscle_ContractionMouseBrainrep_4 9.9e-09
Kcnb2GOBP_Smooth_Muscle_ContractionMouseBrainrep_4 3.0e-20
Kcnb2GOBP_Cation_TransportMouseBrainHP_ad_rep7 7.5e-07
Kcnb2GOBP_Cellular_Macromolecule_LocalizationMouseBrainHP_ad_rep7 6.6e-10
Kcnb2GOBP_Protein_Localization_To_Plasma_MembraneMouseBrainHP_ad_rep7 3.5e-07
Kcnb2GOBP_Regulation_Of_Muscle_System_ProcessMouseBrainHP_ad_rep7 6.3e-07
Kcnb2GOBP_Regulation_Of_Transmembrane_TransportMouseBrainHP_ad_rep7 1.5e-07
Kcnb2GOBP_Regulation_Of_TransportMouseBrainHP_ad_rep7 9.2e-09
Kcnb2GOBP_Transmembrane_TransportMouseBrainHP_ad_rep7 3.4e-07
Kcnb2GOBP_Cation_Transmembrane_TransportMouseBrainHP_polb_rep9 1.4e-07
Kcnb2GOBP_Inorganic_Ion_Transmembrane_TransportMouseBrainHP_polb_rep9 1.1e-07
Kcnb2GOBP_Muscle_ContractionMouseBrainHP_polb_rep9 8.1e-07
Kcnb2GOBP_Protein_Complex_OligomerizationMouseBrainHP_polb_rep9 2.7e-11
Kcnb2GOBP_Protein_HomooligomerizationMouseBrainHP_polb_rep9 1.8e-12
Kcnb2GOBP_Protein_Localization_To_Cell_PeripheryMouseBrainHP_polb_rep9 1.5e-10
Kcnb2GOBP_Regulation_Of_System_ProcessMouseBrainHP_polb_rep9 9.3e-08

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Kcnb2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Kcnb2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Kcnb2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Kcnb2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Kcnb2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource