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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Brwd1 (spascer ID:93871)

Gene summary for Brwd1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Brwd1
	Gene ID	93871
	Gene name	bromodomain and WD repeat domain containing 1
	Synonyms	5330419I02Rik\|D530019K20Rik\|G1-403-16\|Wdr9\|repro5
	Cytomap	16\|16 C4
	Type of gene	protein-coding
	Description	bromodomain and WD repeat-containing protein 1WD repeat domain 9WD repeat-containing protein 9
	Modification date	20220424
	UniProtAcc	Q921C3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Brwd1	GO:0005634	nucleus	21873635	Component
Brwd1	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process
Brwd1	GO:0007010	cytoskeleton organization	21873635	Process
Brwd1	GO:0008360	regulation of cell shape	21873635	Process

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Spatial pattern events for Brwd1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Brwd1	Mouse	Brain	S2	34413515	5.44e-15
Brwd1	Mouse	Brain	S4	34413515	3.83e-12
Brwd1	Mouse	Brain	S6	34413515	7.37e-07
Brwd1	Mouse	Brain	S7	34413515	2.10e-11
Brwd1	Mouse	Brain	rep_4	35141374	1.65e-07
Brwd1	Mouse	Brain	rep_5	35141374	8.18e-10
Brwd1	Mouse	Embryo	rep_4	33188776	1.71e-07
Brwd1	Mouse	Kidney	rep_1	34853151	2.75e-08
Brwd1	Mouse	Brain	rep_1	33469025	1.30e-15
Brwd1	Mouse	Brain	rep_3	35027729	1.32e-15
Brwd1	Mouse	Brain	rep_5	35027729	4.00e-11
Brwd1	Mouse	Testicle	rep_5	34731600	3.91e-06
Brwd1	Mouse	Testicle	rep_6	34731600	2.02e-04
Brwd1	Mouse	Brain	rep_1	35210624	5.22e-10
Brwd1	Mouse	Brain	rep_2	35210624	1.74e-15
Brwd1	Mouse	Brain	rep_3	35210624	8.26e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Brain_rep_5_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Brwd1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Brwd1	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Brwd1	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Brwd1	GOBP_Chromatin_Organization	Mouse	Spinal cord	L7CN45_C1	3.5e-07
Brwd1	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Brwd1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Brwd1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Brwd1	GOBP_Regulation_Of_Cell_Shape	Mouse	Spinal cord	L7CN45_C1	2.7e-06
Brwd1	GOBP_Response_To_Cytokine	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Brwd1	GOBP_Response_To_Interleukin_7	Mouse	Spinal cord	L7CN45_C1	1.9e-07
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Brain	rep_1	7.6e-08
Brwd1	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Brwd1	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Brwd1	GOBP_Chromatin_Organization	Mouse	Brain	rep_3	5.1e-215
Brwd1	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	4.9e-10
Brwd1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	rep_3	3.2e-44
Brwd1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Brain	rep_3	5.0e-45
Brwd1	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	rep_3	2.1e-19
Brwd1	GOBP_Response_To_Cytokine	Mouse	Brain	rep_3	1.2e-08
Brwd1	GOBP_Response_To_Interleukin_7	Mouse	Brain	rep_3	2.7e-132
Brwd1	GOBP_Regulation_Of_Cell_Shape	Mouse	Embryo	rep_14	5.1e-07
Brwd1	GOBP_Response_To_Interleukin_7	Mouse	Embryo	rep_14	6.1e-07
Brwd1	GOBP_Response_To_Cytokine	Mouse	Embryo	rep_1	8.2e-211
Brwd1	GOBP_Chromatin_Organization	Mouse	Embryo	rep_3	2.9e-87
Brwd1	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Embryo	rep_5	2.2e-13
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Kidney	Nep	1.1e-16
Brwd1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	Nep	1.3e-32
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.7e-84
Brwd1	GOBP_Chromatin_Organization	Mouse	Kidney	rep_2	3.0e-63
Brwd1	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Brwd1	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Brwd1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	rep_2	1.3e-133
Brwd1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.9e-85
Brwd1	GOBP_Regulation_Of_Cell_Shape	Mouse	Kidney	rep_2	3.0e-66
Brwd1	GOBP_Response_To_Cytokine	Mouse	Kidney	rep_2	3.1e-14
Brwd1	GOBP_Response_To_Interleukin_7	Mouse	Kidney	rep_2	1.9e-25
Brwd1	GOBP_Response_To_Interleukin_7	Mouse	Liver	CN16-D2	2.4e-07
Brwd1	GOBP_Response_To_Cytokine	Mouse	Liver	rep_16	1.4e-13
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Lymph	MS-1	3.9e-13
Brwd1	GOBP_Chromatin_Organization	Mouse	Lymph	MS-1	9.1e-11
Brwd1	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Brwd1	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	6.7e-17
Brwd1	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Brwd1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Lymph	MS-1	2.4e-16
Brwd1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Lymph	MS-1	2.2e-13
Brwd1	GOBP_Regulation_Of_Cell_Shape	Mouse	Lymph	MS-1	5.2e-14
Brwd1	GOBP_Response_To_Cytokine	Mouse	Lymph	MS-1	5.7e-15
Brwd1	GOBP_Response_To_Cytokine	Mouse	Lung	rep_1	1.2e-17
Brwd1	GOBP_Cell_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.4e-10
Brwd1	GOBP_Chromatin_Organization	Mouse	Brain	HP_ad_rep7	7.6e-11
Brwd1	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Brwd1	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Brwd1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	HP_ad_rep7	3.3e-08
Brwd1	GOBP_Response_To_Cytokine	Mouse	Brain	HP_ad_rep7	2.1e-08
Brwd1	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	5.5e-07
Brwd1	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	HP_polb_rep9	2.9e-08

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Brwd1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Brwd1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Brwd1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Brwd1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Brwd1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Brwd1	C0028960	Oligospermia	1	CTD_human