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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Dach2 (spascer ID:93837)

Gene summary for Dach2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Dach2

Gene ID

93837

Gene namedachshund family transcription factor 2
Synonyms9430028N04Rik
CytomapX E1|X 49.13 cM
Type of geneprotein-coding
Descriptiondachshund homolog 2Dach2fiveprimeDach2threeprimedachshund 2
Modification date20220424
UniProtAcc

Q925Q8


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Dach2

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

21873635

Function
Dach2

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

21873635

Function
Dach2

GO:0005634

nucleus

21873635

Component
Dach2

GO:0005667

transcription regulator complex

21873635

Component
Dach2

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process

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Spatial pattern events for Dach2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Dach2MouseEmbryorep_2 331887769.35e-10
Dach2MouseEmbryorep_3 331887761.13e-14
Dach2MouseEmbryorep_5 331887763.86e-14
Dach2MouseBrainrep_1 334690251.30e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
boxplot


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Spatial pattern pathway has Dach2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Dach2GOBP_Developmental_Process_Involved_In_ReproductionMouseSpinal cordCN94_E1 3.2e-07
Dach2GOBP_ReproductionMouseSpinal cordCN94_E1 7.8e-08
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseBrainrep_34.7e-158
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseBrainrep_32.5e-171
Dach2GOBP_Developmental_Process_Involved_In_ReproductionMouseBrainrep_32.9e-159
Dach2GOBP_Female_Sex_DifferentiationMouseBrainrep_34.1e-185
Dach2GOBP_ReproductionMouseBrainrep_33.4e-125
Dach2GOBP_Sex_DifferentiationMouseBrainrep_36.9e-174
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseEmbryorep_14 2.8e-13
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseEmbryorep_14 1.2e-09
Dach2GOBP_Female_Sex_DifferentiationMouseEmbryorep_14 2.0e-24
Dach2GOBP_Sex_DifferentiationMouseEmbryorep_14 1.7e-14
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseEmbryorep_13.6e-223
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseEmbryorep_1 1.2e-66
Dach2GOBP_Sex_DifferentiationMouseEmbryorep_1 7.0e-66
Dach2GOBP_Female_Sex_DifferentiationMouseEmbryorep_6 2.9e-77
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseKidneyrep_2 6.3e-29
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseKidneyrep_2 3.2e-15
Dach2GOBP_Developmental_Process_Involved_In_ReproductionMouseKidneyrep_2 3.6e-46
Dach2GOBP_Female_Sex_DifferentiationMouseKidneyrep_2 2.4e-26
Dach2GOBP_ReproductionMouseKidneyrep_2 9.0e-46
Dach2GOBP_Sex_DifferentiationMouseKidneyrep_2 4.6e-19
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseLiverCN16-E1 4.8e-07
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseLiverCN65-C1 1.7e-07
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseLymphMS-1 3.2e-07
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseLymphMS-1 4.7e-12
Dach2GOBP_Developmental_Process_Involved_In_ReproductionMouseLymphMS-1 2.2e-10
Dach2GOBP_ReproductionMouseLymphMS-1 1.1e-09
Dach2GOBP_Sex_DifferentiationMouseLymphMS-1 4.7e-12
Dach2GOBP_ReproductionMouseLungrep_1 9.6e-12
Dach2GOBP_Developmental_Process_Involved_In_ReproductionMouseBrainHP_ad_rep7 2.5e-08
Dach2GOBP_ReproductionMouseBrainHP_ad_rep7 7.9e-09
Dach2GOBP_Sex_DifferentiationMouseBrainHP_ad_rep7 6.4e-09
Dach2GOBP_Development_Of_Primary_Female_Sexual_CharacteristicsMouseBrainHP_adpolb_rep1 2.1e-14
Dach2GOBP_Development_Of_Primary_Sexual_CharacteristicsMouseBrainHP_adpolb_rep1 7.3e-09
Dach2GOBP_Female_Sex_DifferentiationMouseBrainHP_adpolb_rep1 1.6e-14

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Dach2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Dach2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Dach2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Dach2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Dach2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Dach2C0025322Premature Menopause1GENOMICS_ENGLAND