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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Smarca5 (spascer ID:93762)

Gene summary for Smarca5

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Smarca5
	Gene ID	93762
	Gene name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
	Synonyms	4933427E24Rik\|D030040M08Rik\|D330027N15Rik\|MommeD4\|Snf2h
	Cytomap	8\|8 C2
	Type of gene	protein-coding
	Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5mSnf2hsucrose nonfermenting protein 2 homolog
	Modification date	20220424
	UniProtAcc	Q91ZW3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Smarca5	GO:0003677	DNA binding	21873635	Function
Smarca5	GO:0005634	nucleus	21873635	Component
Smarca5	GO:0008094	ATP-dependent activity, acting on DNA	21873635	Function
Smarca5	GO:0045944	positive regulation of transcription by RNA polymerase II	21873635	Process

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Spatial pattern events for Smarca5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Smarca5	Mouse	Brain	S4	34413515	1.17e-07
Smarca5	Mouse	Brain	rep_5	35141374	2.79e-06
Smarca5	Mouse	Brain	rep_6	35141374	5.67e-07
Smarca5	Mouse	Embryo	rep_2	33188776	1.37e-14
Smarca5	Mouse	Embryo	rep_3	33188776	1.13e-14
Smarca5	Mouse	Embryo	rep_4	33188776	9.70e-11
Smarca5	Mouse	Embryo	rep_7	33188776	6.94e-15
Smarca5	Mouse	Embryo	rep_12	33188776	4.84e-15
Smarca5	Mouse	Embryo	rep_13	33188776	4.49e-15
Smarca5	Mouse	Kidney	rep_1	34853151	3.46e-06
Smarca5	Mouse	Brain	rep_1	35027729	9.60e-06
Smarca5	Mouse	Brain	rep_2	35027729	7.30e-06
Smarca5	Mouse	Brain	rep_6	35210624	1.29e-13
Smarca5	Mouse	Brain	rep_7	35210624	2.21e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E

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Spatial pattern pathway has Smarca5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	6.2e-07
Smarca5	GOBP_Nucleosome_Positioning	Mouse	Spinal cord	L7bCN01_D2	4.3e-06
Smarca5	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7bCN02_E1	7.5e-06
Smarca5	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Spinal cord	L7bCN02_E1	3.4e-06
Smarca5	GOBP_Chromatin_Remodeling_At_Centromere	Mouse	Spinal cord	L7bCN05_D1	8.9e-06
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Spinal cord	L7CN44_C1	6.1e-06
Smarca5	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Smarca5	GOBP_Chromatin_Organization	Mouse	Spinal cord	L7CN45_C1	3.5e-07
Smarca5	GOBP_Chromatin_Remodeling	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Smarca5	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Spinal cord	L7CN45_C1	8.1e-07
Smarca5	GOBP_Dna_Packaging	Mouse	Spinal cord	L7CN45_C1	7.6e-07
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Spinal cord	L7CN45_C1	1.5e-08
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Spinal cord	L7CN45_C1	4.0e-09
Smarca5	GOBP_Nucleosome_Assembly	Mouse	Spinal cord	L7CN45_C1	5.5e-06
Smarca5	GOBP_Nucleosome_Organization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Smarca5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Smarca5	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Smarca5	GOBP_Response_To_Cytokine	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Spinal cord	L7CN45_C1	3.3e-07
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Brain	rep_11	3.6e-05
Smarca5	GOBP_Nucleosome_Assembly	Mouse	Brain	rep_17	6.9e-07
Smarca5	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	rep_19	1.5e-05
Smarca5	GOBP_Nucleosome_Organization	Mouse	Brain	rep_19	1.2e-06
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Brain	rep_27	1.0e-06
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Brain	rep_41	6.9e-05
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Brain	rep_75	9.8e-05
Smarca5	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Brain	rep_1	2.3e-11
Smarca5	GOBP_Histone_Exchange	Mouse	Brain	rep_1	1.6e-15
Smarca5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Smarca5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Brain	rep_3	3.9e-154
Smarca5	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	rep_3	1.7e-35
Smarca5	GOBP_Chromatin_Organization	Mouse	Brain	rep_3	5.1e-215
Smarca5	GOBP_Chromatin_Remodeling	Mouse	Brain	rep_3	4.4e-194
Smarca5	GOBP_Chromatin_Remodeling_At_Centromere	Mouse	Brain	rep_3	3.4e-117
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Brain	rep_3	7.4e-54
Smarca5	GOBP_Dna_Packaging	Mouse	Brain	rep_3	3.0e-32
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Brain	rep_3	2.4e-164
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	9.4e-206
Smarca5	GOBP_Nucleosome_Organization	Mouse	Brain	rep_3	1.5e-62
Smarca5	GOBP_Nucleosome_Positioning	Mouse	Brain	rep_3	1.4e-86
Smarca5	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	3.1e-102
Smarca5	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Brain	rep_3	5.3e-122
Smarca5	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Mouse	Brain	rep_3	2.8e-164
Smarca5	GOBP_Response_To_Cytokine	Mouse	Brain	rep_3	1.2e-08
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Brain	rep_3	9.6e-172
Smarca5	GOBP_Nucleosome_Assembly	Mouse	Brain	rep_7	1.4e-138
Smarca5	GOBP_Chromatin_Remodeling_At_Centromere	Mouse	Embryo	rep_6	3.3e-07
Smarca5	GOBP_Histone_Exchange	Mouse	Embryo	rep_6	2.1e-22
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Embryo	rep_14	1.7e-26
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Embryo	rep_14	2.1e-08
Smarca5	GOBP_Dna_Packaging	Mouse	Embryo	rep_14	2.5e-08
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Embryo	rep_14	3.3e-18
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Embryo	rep_14	2.5e-32
Smarca5	GOBP_Nucleosome_Assembly	Mouse	Embryo	rep_14	2.1e-19
Smarca5	GOBP_Nucleosome_Organization	Mouse	Embryo	rep_14	1.7e-10
Smarca5	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Embryo	rep_14	2.2e-11
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Embryo	rep_14	5.8e-43
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Embryo	rep_1	2.8e-41
Smarca5	GOBP_Response_To_Cytokine	Mouse	Embryo	rep_1	8.2e-211
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Smarca5	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Mouse	Embryo	rep_2	3.9e-22
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Embryo	rep_2	9.5e-207
Smarca5	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Embryo	rep_3	4.5e-65
Smarca5	GOBP_Chromatin_Organization	Mouse	Embryo	rep_3	2.9e-87
Smarca5	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Embryo	rep_3	1.5e-48
Smarca5	GOBP_Dna_Packaging	Mouse	Embryo	rep_3	1.5e-48
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	1.5e-267
Smarca5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Smarca5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Smarca5	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Kidney	Nep	4.9e-40
Smarca5	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Kidney	rep_2	1.1e-38
Smarca5	GOBP_Chromatin_Organization	Mouse	Kidney	rep_2	3.0e-63
Smarca5	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Kidney	rep_2	1.4e-38
Smarca5	GOBP_Dna_Packaging	Mouse	Kidney	rep_2	8.1e-32
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Kidney	rep_2	6.1e-40
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Kidney	rep_2	1.4e-20
Smarca5	GOBP_Histone_Exchange	Mouse	Kidney	rep_2	6.1e-46
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	7.7e-30
Smarca5	GOBP_Nucleosome_Organization	Mouse	Kidney	rep_2	4.7e-25
Smarca5	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	2.1e-103
Smarca5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Smarca5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Smarca5	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Kidney	rep_2	1.1e-35
Smarca5	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Mouse	Kidney	rep_2	4.8e-51
Smarca5	GOBP_Response_To_Cytokine	Mouse	Kidney	rep_2	3.1e-14
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Kidney	rep_2	1.8e-20
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Liver	CN65-C1	2.3e-09
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Liver	CN65-C1	2.7e-10
Smarca5	GOBP_Nucleosome_Assembly	Mouse	Liver	CN65-C1	2.7e-09
Smarca5	GOBP_Nucleosome_Organization	Mouse	Liver	CN65-C1	1.6e-09
Smarca5	GOBP_Histone_Exchange	Mouse	Liver	CN73-C1	3.8e-07
Smarca5	GOBP_Response_To_Cytokine	Mouse	Liver	rep_16	1.4e-13
Smarca5	GOBP_Nucleosome_Positioning	Mouse	Liver	rep_23	2.4e-16
Smarca5	GOBP_Nucleosome_Positioning	Mouse	Brain	rep_1	1.0e-07
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Lymph	MS-1	1.3e-08
Smarca5	GOBP_Chromatin_Organization	Mouse	Lymph	MS-1	9.1e-11
Smarca5	GOBP_Chromatin_Remodeling_At_Centromere	Mouse	Lymph	MS-1	6.5e-11
Smarca5	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Lymph	MS-1	3.5e-13
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Lymph	MS-1	8.4e-11
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	1.8e-10
Smarca5	GOBP_Nucleosome_Positioning	Mouse	Lymph	MS-1	6.5e-07
Smarca5	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	7.3e-12
Smarca5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Smarca5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Smarca5	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Lymph	MS-1	2.3e-09
Smarca5	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Mouse	Lymph	MS-1	1.0e-13
Smarca5	GOBP_Response_To_Cytokine	Mouse	Lymph	MS-1	5.7e-15
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Lymph	MS-1	3.2e-08
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lung	rep_1	5.8e-10
Smarca5	GOBP_Response_To_Cytokine	Mouse	Lung	rep_1	1.2e-17
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Brain	rep_7	7.7e-09
Smarca5	GOBP_Centromere_Complex_Assembly	Mouse	Brain	HP_ad_rep3	1.3e-08
Smarca5	GOBP_Chromatin_Remodeling_At_Centromere	Mouse	Brain	HP_ad_rep3	2.0e-07
Smarca5	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	HP_ad_rep7	6.7e-07
Smarca5	GOBP_Chromatin_Organization	Mouse	Brain	HP_ad_rep7	7.6e-11
Smarca5	GOBP_Chromatin_Remodeling	Mouse	Brain	HP_ad_rep7	5.3e-11
Smarca5	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Smarca5	GOBP_Dna_Conformation_Change	Mouse	Brain	HP_ad_rep7	1.3e-13
Smarca5	GOBP_Dna_Packaging	Mouse	Brain	HP_ad_rep7	8.5e-11
Smarca5	GOBP_Heterochromatin_Organization	Mouse	Brain	HP_ad_rep7	1.3e-15
Smarca5	GOBP_Histone_Exchange	Mouse	Brain	HP_ad_rep7	5.5e-14
Smarca5	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Smarca5	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-11
Smarca5	GOBP_Nucleosome_Organization	Mouse	Brain	HP_ad_rep7	6.7e-07
Smarca5	GOBP_Nucleosome_Positioning	Mouse	Brain	HP_ad_rep7	3.0e-10
Smarca5	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	4.4e-07
Smarca5	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Smarca5	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11
Smarca5	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Brain	HP_ad_rep7	9.8e-13
Smarca5	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Mouse	Brain	HP_ad_rep7	9.0e-11
Smarca5	GOBP_Response_To_Cytokine	Mouse	Brain	HP_ad_rep7	2.1e-08
Smarca5	GOBP_Response_To_Leukemia_Inhibitory_Factor	Mouse	Brain	HP_ad_rep7	2.3e-07
Smarca5	GOBP_Nucleosome_Assembly	Mouse	Brain	HP_ad_rep8	1.6e-16
Smarca5	GOBP_Dna_Templated_Transcription_Initiation	Mouse	Brain	HP_polb_rep9	8.2e-07

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Smarca5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Smarca5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Smarca5 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
SMARCA5	Uterus	mid	Glandular_secretory	GNL2,SPRY4,BTRC, etc.	0.26
SMARCA5	Uterus	mid	Ciliated	GNL2,SPRY4,BTRC, etc.	0.298
SMARCA5	Uterus	proliferative	SOX9	BDP1,XRN1,HNRNPU, etc.	0.543
SMARCA5	Uterus	proliferative	SOX9_LGR5	BDP1,XRN1,HNRNPU, etc.	0.302
SMARCA5	Uterus	proliferative	SOX9_prolif	BDP1,XRN1,HNRNPU, etc.	0.344

Motif information.

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Related Drugs for Smarca5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Smarca5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Smarca5	C0279980	Extra-osseous Ewing's sarcoma	1	ORPHANET