Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Echs1 (spascer ID:93747)

Gene summary for Echs1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Echs1
	Gene ID	93747
	Gene name	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
	Synonyms	C80529\|SCEH\|mECH\|mECH1
	Cytomap	7\|7 F4
	Type of gene	protein-coding
	Description	enoyl-CoA hydratase, mitochondrialenoyl-CoA hydratase 1short-chain enoyl-CoA hydratase
	Modification date	20220424
	UniProtAcc	Q8BH95

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Echs1	GO:0004300	enoyl-CoA hydratase activity	21873635	Function
Echs1	GO:0005739	mitochondrion	21873635	Component
Echs1	GO:0006635	fatty acid beta-oxidation	21873635	Process

Top

Spatial pattern events for Echs1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Echs1	Mouse	Brain	S3	34413515	3.19e-10
Echs1	Mouse	Brain	S4	34413515	1.37e-15
Echs1	Mouse	Brain	S6	34413515	5.49e-08
Echs1	Mouse	Brain	S7	34413515	3.22e-14
Echs1	Mouse	Brain	rep_1	35141374	5.93e-09
Echs1	Mouse	Brain	rep_2	35141374	5.75e-15
Echs1	Mouse	Brain	rep_3	35141374	1.64e-15
Echs1	Mouse	Brain	rep_4	35141374	2.15e-12
Echs1	Mouse	Brain	rep_5	35141374	1.48e-06
Echs1	Mouse	Brain	rep_6	35141374	1.12e-07
Echs1	Mouse	Kidney	CLP	34003797	2.19e-15
Echs1	Mouse	Kidney	IRI	34003797	2.29e-15
Echs1	Mouse	Kidney	Sham	34003797	4.30e-15
Echs1	Mouse	Kidney	rep_1	34853151	2.42e-15
Echs1	Mouse	Kidney	rep_2	34853151	6.15e-06
Echs1	Mouse	Kidney	rep_3	34853151	4.93e-15
Echs1	Mouse	Kidney	rep_5	34853151	3.18e-15
Echs1	Mouse	Brain	rep_1	33469025	8.20e-10
Echs1	Mouse	Liver	rep_17	35021063	2.88e-10
Echs1	Mouse	Liver	rep_19	35021063	5.06e-08
Echs1	Mouse	Liver	rep_21	35021063	4.28e-06
Echs1	Mouse	Brain	rep_1	35027729	2.98e-15
Echs1	Mouse	Brain	rep_2	35027729	1.57e-15
Echs1	Mouse	Brain	rep_3	35027729	1.32e-15
Echs1	Mouse	Brain	rep_4	35027729	1.92e-06
Echs1	Mouse	Brain	rep_5	35027729	1.46e-15
Echs1	Mouse	Intestine	rep_2	35149721	5.49e-15
Echs1	Mouse	Intestine	rep_3	35149721	5.21e-15
Echs1	Mouse	Intestine	rep_4	35149721	3.90e-15
Echs1	Mouse	Testicle	rep_3	34731600	2.39e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_17_H&E
Liver_rep_19_H&E
Liver_rep_21_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

Top

Spatial pattern pathway has Echs1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Echs1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-07
Echs1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	3.7e-06
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Spinal cord	L7bCN02_E1	5.4e-07
Echs1	GOBP_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	8.9e-07
Echs1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Echs1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.0e-07
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Echs1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.6e-10
Echs1	GOBP_Lipid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Echs1	GOBP_Lipid_Modification	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Echs1	GOBP_Lipid_Oxidation	Mouse	Spinal cord	L7CN45_C1	8.8e-07
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.2e-09
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Echs1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_11	2.7e-06
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	rep_71	3.6e-06
Echs1	GOBP_Lipid_Modification	Mouse	Brain	rep_71	7.0e-06
Echs1	GOBP_Lipid_Oxidation	Mouse	Brain	rep_71	3.6e-06
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_71	8.1e-05
Echs1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Brain	rep_3	3.5e-106
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	rep_3	1.7e-210
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Brain	rep_3	1.3e-180
Echs1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-41
Echs1	GOBP_Lipid_Catabolic_Process	Mouse	Brain	rep_3	1.4e-121
Echs1	GOBP_Lipid_Modification	Mouse	Brain	rep_3	4.5e-101
Echs1	GOBP_Lipid_Oxidation	Mouse	Brain	rep_3	1.2e-128
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_3	2.0e-175
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	3.2e-119
Echs1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	rep_3	9.6e-181
Echs1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Echs1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Echs1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Embryo	rep_14	6.6e-12
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Embryo	rep_14	6.7e-36
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-09
Echs1	GOBP_Lipid_Modification	Mouse	Embryo	rep_14	3.4e-09
Echs1	GOBP_Lipid_Oxidation	Mouse	Embryo	rep_14	9.5e-24
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	7.1e-14
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_14	7.3e-13
Echs1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.3e-13
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Echs1	GOBP_Lipid_Metabolic_Process	Mouse	Embryo	rep_1	2.1e-39
Echs1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Echs1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Embryo	rep_3	2.1e-07
Echs1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.7e-52
Echs1	GOBP_Lipid_Catabolic_Process	Mouse	Embryo	rep_3	2.1e-07
Echs1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_4	0.0e+00
Echs1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Echs1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Kidney	rep_2	2.5e-44
Echs1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	7.4e-43
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Kidney	rep_2	2.0e-46
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Kidney	rep_2	7.7e-56
Echs1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Kidney	rep_2	2.1e-55
Echs1	GOBP_Lipid_Catabolic_Process	Mouse	Kidney	rep_2	1.4e-56
Echs1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-78
Echs1	GOBP_Lipid_Modification	Mouse	Kidney	rep_2	1.7e-37
Echs1	GOBP_Lipid_Oxidation	Mouse	Kidney	rep_2	2.1e-13
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	2.6e-58
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-73
Echs1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	1.3e-83
Echs1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Echs1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Echs1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Liver	CN73-C1	9.9e-09
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Intestine	rep_2	2.4e-11
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Intestine	rep_2	3.7e-18
Echs1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Intestine	rep_2	3.9e-25
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Intestine	rep_2	1.5e-14
Echs1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Lymph	MS-1	3.4e-07
Echs1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-14
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Lymph	MS-1	7.8e-09
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Lymph	MS-1	6.3e-09
Echs1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Lymph	MS-1	8.4e-16
Echs1	GOBP_Lipid_Catabolic_Process	Mouse	Lymph	MS-1	2.6e-07
Echs1	GOBP_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	9.7e-11
Echs1	GOBP_Lipid_Modification	Mouse	Lymph	MS-1	6.5e-09
Echs1	GOBP_Lipid_Oxidation	Mouse	Lymph	MS-1	3.2e-11
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.8e-07
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Echs1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.1e-10
Echs1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Echs1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Echs1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	4.7e-07
Echs1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-10
Echs1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-13
Echs1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Echs1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Echs1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.9e-07
Echs1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	HP_polb_rep9	2.3e-12
Echs1	GOBP_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-11
Echs1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-11
Echs1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

Top

Echs1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Echs1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Echs1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Echs1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Echs1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Echs1	C4225391	MITOCHONDRIAL SHORT-CHAIN ENOYL-CoA HYDRATASE 1 DEFICIENCY	9	CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
Echs1	C0023264	Leigh Disease	2	CTD_human
Echs1	C0751267	Encephalopathy, Subacute Necrotizing, Infantile	2	CTD_human
Echs1	C0751268	Encephalopathy, Subacute Necrotizing, Juvenile	2	CTD_human
Echs1	C0001973	Alcoholic Intoxication, Chronic	1	PSYGENET
Echs1	C0019193	Hepatitis, Toxic	1	CTD_human
Echs1	C0024623	Malignant neoplasm of stomach	1	CTD_human
Echs1	C0028754	Obesity	1	CTD_human
Echs1	C0038356	Stomach Neoplasms	1	CTD_human
Echs1	C0860207	Drug-Induced Liver Disease	1	CTD_human
Echs1	C1262760	Hepatitis, Drug-Induced	1	CTD_human
Echs1	C1708349	Hereditary Diffuse Gastric Cancer	1	CTD_human
Echs1	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
Echs1	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
Echs1	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human