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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Plvap (spascer ID:84094)

Gene summary for Plvap

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Plvap
	Gene ID	84094
	Gene name	plasmalemma vesicle associated protein
	Synonyms	MECA32\|Pv1
	Cytomap	8 B3.3\|8 34.43 cM
	Type of gene	protein-coding
	Description	plasmalemma vesicle-associated proteinMECA-32 antigenplasmalemma vesicle protein 1
	Modification date	20220424
	UniProtAcc	Q91VC4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Plvap	GO:0002693	positive regulation of cellular extravasation	21873635	Process
Plvap	GO:0005901	caveola	21873635	Component
Plvap	GO:0043114	regulation of vascular permeability	21873635	Process

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Spatial pattern events for Plvap

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Plvap	Mouse	Brain	S1	34413515	4.84e-14
Plvap	Mouse	Brain	S2	34413515	1.56e-15
Plvap	Mouse	Brain	S3	34413515	3.08e-10
Plvap	Mouse	Brain	S4	34413515	1.37e-15
Plvap	Mouse	Brain	S6	34413515	2.66e-15
Plvap	Mouse	Brain	S7	34413515	1.55e-15
Plvap	Mouse	Brain	rep_2	35141374	1.69e-15
Plvap	Mouse	Brain	rep_3	35141374	3.00e-15
Plvap	Mouse	Brain	rep_4	35141374	1.57e-15
Plvap	Mouse	Brain	rep_5	35141374	6.48e-14
Plvap	Mouse	Brain	rep_6	35141374	8.74e-09
Plvap	Mouse	Embryo	rep_2	33188776	2.68e-07
Plvap	Mouse	Embryo	rep_3	33188776	2.98e-11
Plvap	Mouse	Embryo	rep_1	34489600	3.74e-16
Plvap	Mouse	Embryo	rep_2	34489600	4.14e-16
Plvap	Mouse	Embryo	rep_3	34489600	4.04e-16
Plvap	Mouse	Embryo	rep_4	34489600	3.67e-16
Plvap	Mouse	Embryo	rep_5	34489600	4.08e-16
Plvap	Mouse	Embryo	rep_6	34489600	3.64e-16
Plvap	Mouse	Kidney	CLP	34003797	2.19e-15
Plvap	Mouse	Kidney	IRI	34003797	2.29e-15
Plvap	Mouse	Kidney	Sham	34003797	2.58e-15
Plvap	Mouse	Kidney	rep_1	34853151	2.42e-15
Plvap	Mouse	Kidney	rep_2	34853151	5.42e-15
Plvap	Mouse	Kidney	rep_3	34853151	2.94e-15
Plvap	Mouse	Kidney	rep_4	34853151	4.07e-15
Plvap	Mouse	Kidney	rep_5	34853151	3.18e-15
Plvap	Mouse	Brain	rep_1	33469025	1.30e-15
Plvap	Mouse	Liver	rep_20	35021063	9.91e-15
Plvap	Mouse	Liver	rep_21	35021063	8.03e-15
Plvap	Mouse	Liver	rep_22	35021063	1.07e-14
Plvap	Mouse	Brain	rep_3	35027729	2.38e-15
Plvap	Mouse	Brain	rep_5	35027729	2.59e-06
Plvap	Mouse	Intestine	rep_2	35149721	3.57e-07
Plvap	Mouse	Intestine	rep_4	35149721	9.49e-06
Plvap	Mouse	Lymph	MS-1	0	3.72e-14
Plvap	Mouse	Lymph	MS-2	0	2.72e-07
Plvap	Mouse	Lymph	A1	0	1.09e-10
Plvap	Mouse	Lymph	B1	0	1.13e-10
Plvap	Mouse	Lung	rep_1	35290801	4.52e-15
Plvap	Mouse	Lung	rep_2	35290801	7.23e-15
Plvap	Mouse	Lung	rep_3	35290801	5.26e-15
Plvap	Mouse	Lung	rep_4	35290801	3.04e-15
Plvap	Mouse	Brain	rep_1	35210624	1.74e-15
Plvap	Mouse	Brain	rep_2	35210624	1.74e-15
Plvap	Mouse	Brain	rep_3	35210624	1.83e-07
Plvap	Mouse	Brain	rep_6	35210624	8.04e-10
Plvap	Mouse	Brain	rep_7	35210624	7.82e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_20_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Plvap envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Plvap	GOBP_Cellular_Extravasation	Mouse	Spinal cord	CN93_D2	7.7e-06
Plvap	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Plvap	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	CN94_E1	6.6e-06
Plvap	GOBP_Leukocyte_Migration	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Plvap	GOBP_Mapk_Cascade	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Spinal cord	L7CN45_C1	8.9e-08
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Spinal cord	L7CN45_C1	2.8e-06
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Plvap	GOBP_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Spinal cord	L7CN45_C1	1.5e-08
Plvap	GOBP_Response_To_Cytokine	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Plvap	GOBP_Response_To_Tumor_Necrosis_Factor	Mouse	Spinal cord	L7CN45_C1	1.9e-08
Plvap	GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.0e-06
Plvap	GOBP_Cell_Migration	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Plvap	GOBP_Locomotion	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Brain	rep_71	9.0e-05
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Brain	rep_71	1.5e-05
Plvap	GOBP_Cellular_Extravasation	Mouse	Brain	rep_1	1.3e-56
Plvap	GOBP_Positive_Regulation_Of_Cellular_Extravasation	Mouse	Brain	rep_1	1.1e-46
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Brain	rep_1	5.4e-12
Plvap	GOBP_Regulation_Of_Cellular_Extravasation	Mouse	Brain	rep_1	6.0e-28
Plvap	GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_Pathway	Mouse	Brain	rep_1	1.5e-18
Plvap	GOBP_Cell_Migration	Mouse	Brain	rep_3	4.9e-108
Plvap	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	4.9e-10
Plvap	GOBP_Leukocyte_Migration	Mouse	Brain	rep_3	5.3e-139
Plvap	GOBP_Locomotion	Mouse	Brain	rep_3	5.4e-74
Plvap	GOBP_Mapk_Cascade	Mouse	Brain	rep_3	4.8e-123
Plvap	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.9e-97
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Brain	rep_3	6.5e-36
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Brain	rep_3	8.2e-109
Plvap	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.4e-111
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Brain	rep_3	6.8e-34
Plvap	GOBP_Response_To_Cytokine	Mouse	Brain	rep_3	1.2e-08
Plvap	GOBP_Response_To_Tumor_Necrosis_Factor	Mouse	Brain	rep_4	1.6e-12
Plvap	GOBP_Regulation_Of_Cellular_Extravasation	Mouse	Embryo	rep_6	4.4e-07
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Embryo	rep_6	2.8e-10
Plvap	GOBP_Cellular_Extravasation	Mouse	Embryo	rep_14	1.2e-16
Plvap	GOBP_Leukocyte_Migration	Mouse	Embryo	rep_14	2.9e-16
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Embryo	rep_14	6.4e-54
Plvap	GOBP_Response_To_Tumor_Necrosis_Factor	Mouse	Embryo	rep_14	4.5e-25
Plvap	GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_Pathway	Mouse	Embryo	rep_14	6.6e-23
Plvap	GOBP_Cell_Migration	Mouse	Embryo	rep_1	7.4e-36
Plvap	GOBP_Locomotion	Mouse	Embryo	rep_1	1.7e-10
Plvap	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	7.3e-23
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Embryo	rep_1	3.1e-60
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Embryo	rep_1	1.9e-40
Plvap	GOBP_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	9.5e-143
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Embryo	rep_1	4.5e-57
Plvap	GOBP_Response_To_Cytokine	Mouse	Embryo	rep_1	8.2e-211
Plvap	GOBP_Cellular_Extravasation	Mouse	Embryo	rep_6	1.1e-09
Plvap	GOBP_Cell_Migration	Mouse	Kidney	Nep	5.3e-07
Plvap	GOBP_Locomotion	Mouse	Kidney	Nep	5.3e-07
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Kidney	Nep	5.3e-07
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Kidney	Nep	5.3e-07
Plvap	GOBP_Response_To_Tumor_Necrosis_Factor	Mouse	Kidney	Sham	1.8e-10
Plvap	GOBP_Cell_Migration	Mouse	Kidney	rep_2	4.7e-40
Plvap	GOBP_Cellular_Extravasation	Mouse	Kidney	rep_2	1.2e-23
Plvap	GOBP_Leukocyte_Migration	Mouse	Kidney	rep_2	8.5e-09
Plvap	GOBP_Locomotion	Mouse	Kidney	rep_2	2.1e-43
Plvap	GOBP_Mapk_Cascade	Mouse	Kidney	rep_2	1.1e-19
Plvap	GOBP_Positive_Regulation_Of_Cellular_Extravasation	Mouse	Kidney	rep_2	7.1e-40
Plvap	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	1.2e-85
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Kidney	rep_2	1.6e-133
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Kidney	rep_2	2.1e-54
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Kidney	rep_2	5.4e-74
Plvap	GOBP_Regulation_Of_Cellular_Extravasation	Mouse	Kidney	rep_2	7.4e-18
Plvap	GOBP_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	2.5e-84
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Kidney	rep_2	5.7e-119
Plvap	GOBP_Response_To_Cytokine	Mouse	Kidney	rep_2	3.1e-14
Plvap	GOBP_Positive_Regulation_Of_Cellular_Extravasation	Mouse	Liver	CN65-C1	5.1e-08
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Liver	CN73-C1	2.7e-07
Plvap	GOBP_Positive_Regulation_Of_Cellular_Extravasation	Mouse	Liver	rep_15	1.3e-16
Plvap	GOBP_Regulation_Of_Cellular_Extravasation	Mouse	Liver	rep_15	1.7e-07
Plvap	GOBP_Cellular_Extravasation	Mouse	Liver	rep_16	7.2e-14
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Liver	rep_16	2.6e-07
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Liver	rep_16	2.3e-09
Plvap	GOBP_Response_To_Cytokine	Mouse	Liver	rep_16	1.4e-13
Plvap	GOBP_Cell_Migration	Mouse	Liver	rep_26	1.6e-10
Plvap	GOBP_Locomotion	Mouse	Liver	rep_26	1.6e-10
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Liver	rep_26	1.6e-10
Plvap	GOBP_Cell_Migration	Mouse	Lymph	MS-1	5.7e-13
Plvap	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	6.7e-17
Plvap	GOBP_Leukocyte_Migration	Mouse	Lymph	MS-1	5.5e-13
Plvap	GOBP_Locomotion	Mouse	Lymph	MS-1	1.2e-12
Plvap	GOBP_Mapk_Cascade	Mouse	Lymph	MS-1	8.8e-20
Plvap	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	1.6e-18
Plvap	GOBP_Positive_Regulation_Of_Leukocyte_Migration	Mouse	Lymph	MS-1	8.6e-19
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Lymph	MS-1	4.0e-14
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Lymph	MS-1	2.1e-13
Plvap	GOBP_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	2.2e-14
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Lymph	MS-1	1.6e-16
Plvap	GOBP_Response_To_Cytokine	Mouse	Lymph	MS-1	5.7e-15
Plvap	GOBP_Response_To_Tumor_Necrosis_Factor	Mouse	Lymph	MS-1	1.7e-14
Plvap	GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	4.1e-10
Plvap	GOBP_Cellular_Extravasation	Mouse	Lung	rep_1	2.5e-13
Plvap	GOBP_Response_To_Cytokine	Mouse	Lung	rep_1	1.2e-17
Plvap	GOBP_Cellular_Extravasation	Mouse	Brain	rep_4	4.7e-53
Plvap	GOBP_Positive_Regulation_Of_Cellular_Extravasation	Mouse	Brain	rep_4	2.1e-43
Plvap	GOBP_Cell_Migration	Mouse	Brain	HP_ad_rep7	2.2e-07
Plvap	GOBP_Cellular_Extravasation	Mouse	Brain	HP_ad_rep7	4.9e-10
Plvap	GOBP_Leukocyte_Migration	Mouse	Brain	HP_ad_rep7	4.3e-08
Plvap	GOBP_Locomotion	Mouse	Brain	HP_ad_rep7	3.8e-07
Plvap	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	5.5e-07
Plvap	GOBP_Regulation_Of_Cellular_Component_Movement	Mouse	Brain	HP_ad_rep7	4.0e-07
Plvap	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	1.8e-09
Plvap	GOBP_Regulation_Of_Leukocyte_Migration	Mouse	Brain	HP_ad_rep7	7.3e-09
Plvap	GOBP_Response_To_Cytokine	Mouse	Brain	HP_ad_rep7	2.1e-08
Plvap	GOBP_Positive_Regulation_Of_Cellular_Extravasation	Mouse	Brain	HP_adpolb_rep4	1.4e-08
Plvap	GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep1	3.6e-07
Plvap	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	5.5e-07
Plvap	GOBP_Positive_Regulation_Of_Locomotion	Mouse	Brain	HP_polb_rep9	6.5e-08
Plvap	GOBP_Regulation_Of_Cellular_Extravasation	Mouse	Brain	HP_polb_rep9	2.8e-07

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Plvap function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Plvap function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Plvap envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Plvap

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Plvap

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Plvap	C4748579	DIARRHEA 10, PROTEIN-LOSING ENTEROPATHY TYPE	3	ORPHANET;UNIPROT
Plvap	C2239176	Liver carcinoma	1	CTD_human
Plvap	C4014516	DIARRHEA 7, PROTEIN-LOSING ENTEROPATHY TYPE	1	ORPHANET