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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Herpud2 (spascer ID:80517)

Gene summary for Herpud2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Herpud2
	Gene ID	80517
	Gene name	HERPUD family member 2
	Synonyms	5031400M07Rik\|AB041580
	Cytomap	9\|9 A4
	Type of gene	protein-coding
	Description	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
	Modification date	20220424
	UniProtAcc	Q9JJC9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Herpud2	GO:0030968	endoplasmic reticulum unfolded protein response	21873635	Process

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Spatial pattern events for Herpud2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Herpud2	Mouse	Kidney	CLP	34003797	4.51e-13
Herpud2	Mouse	Testicle	rep_1	34731600	1.93e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E

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Spatial pattern pathway has Herpud2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Herpud2	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Spinal cord	CN94_E1	3.2e-07
Herpud2	GOBP_Gamete_Generation	Mouse	Spinal cord	CN94_E1	3.1e-07
Herpud2	GOBP_Male_Gamete_Generation	Mouse	Spinal cord	CN94_E1	4.7e-06
Herpud2	GOBP_Reproduction	Mouse	Spinal cord	CN94_E1	7.8e-08
Herpud2	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Spinal cord	L7CN45_C1	7.6e-08
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Herpud2	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Herpud2	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Spinal cord	L7CN45_C1	5.1e-07
Herpud2	GOBP_Gamete_Generation	Mouse	Brain	rep_27	5.2e-05
Herpud2	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	rep_3	1.4e-162
Herpud2	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Brain	rep_3	2.9e-159
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Brain	rep_3	3.4e-151
Herpud2	GOBP_Gamete_Generation	Mouse	Brain	rep_3	1.3e-194
Herpud2	GOBP_Male_Gamete_Generation	Mouse	Brain	rep_3	1.6e-190
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Brain	rep_3	1.2e-58
Herpud2	GOBP_Reproduction	Mouse	Brain	rep_3	3.4e-125
Herpud2	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Brain	rep_3	6.3e-133
Herpud2	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	rep_3	8.7e-153
Herpud2	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_14	8.7e-22
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Embryo	rep_14	2.5e-19
Herpud2	GOBP_Gamete_Generation	Mouse	Embryo	rep_14	6.5e-07
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Embryo	rep_14	5.9e-07
Herpud2	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_14	7.2e-14
Herpud2	GOBP_Male_Gamete_Generation	Mouse	Embryo	rep_1	0.0e+00
Herpud2	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_3	0.0e+00
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Embryo	rep_3	1.7e-305
Herpud2	GOBP_Gamete_Generation	Mouse	Embryo	rep_3	2.1e-220
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Embryo	rep_3	8.7e-222
Herpud2	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Embryo	rep_3	1.8e-13
Herpud2	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_3	2.3e-263
Herpud2	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Kidney	rep_2	3.6e-46
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Kidney	rep_2	5.3e-42
Herpud2	GOBP_Gamete_Generation	Mouse	Kidney	rep_2	5.0e-33
Herpud2	GOBP_Male_Gamete_Generation	Mouse	Kidney	rep_2	5.8e-51
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Kidney	rep_2	1.6e-53
Herpud2	GOBP_Reproduction	Mouse	Kidney	rep_2	9.0e-46
Herpud2	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Kidney	rep_2	1.2e-89
Herpud2	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Lymph	MS-1	2.2e-10
Herpud2	GOBP_Gamete_Generation	Mouse	Lymph	MS-1	7.7e-08
Herpud2	GOBP_Male_Gamete_Generation	Mouse	Lymph	MS-1	1.6e-08
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Herpud2	GOBP_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Herpud2	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Lymph	MS-1	1.7e-11
Herpud2	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Lymph	MS-1	2.8e-07
Herpud2	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Lymph	PBS	1.2e-07
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Lymph	PBS	2.4e-07
Herpud2	GOBP_Reproduction	Mouse	Lung	rep_1	9.6e-12
Herpud2	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Brain	HP_ad_rep7	2.5e-08
Herpud2	GOBP_Gamete_Generation	Mouse	Brain	HP_ad_rep7	1.3e-11
Herpud2	GOBP_Multicellular_Organism_Reproduction	Mouse	Brain	HP_ad_rep7	6.1e-08
Herpud2	GOBP_Reproduction	Mouse	Brain	HP_ad_rep7	7.9e-09
Herpud2	GOBP_Male_Gamete_Generation	Mouse	Brain	HP_ad_rep8	8.4e-07
Herpud2	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	HP_polb_rep9	2.8e-08
Herpud2	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Brain	HP_polb_rep9	2.7e-13
Herpud2	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Brain	HP_polb_rep9	3.5e-12
Herpud2	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	HP_polb_rep9	5.0e-08

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Herpud2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Herpud2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Herpud2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Herpud2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Herpud2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Herpud2	C0087031	Juvenile-Onset Still Disease	1	CTD_human
Herpud2	C3495559	Juvenile arthritis	1	CTD_human
Herpud2	C3714758	Juvenile psoriatic arthritis	1	CTD_human
Herpud2	C4552091	Polyarthritis, Juvenile, Rheumatoid Factor Negative	1	CTD_human
Herpud2	C4704862	Polyarthritis, Juvenile, Rheumatoid Factor Positive	1	CTD_human