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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ralgps2 (spascer ID:78255)

Gene summary for Ralgps2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ralgps2
	Gene ID	78255
	Gene name	Ral GEF with PH domain and SH3 binding motif 2
	Synonyms	1810020P17Rik\|2210408F11Rik\|4921528G01Rik\|9130014M22Rik\|AU043409\|AW046161
	Cytomap	1\|1 G3
	Type of gene	protein-coding
	Description	ras-specific guanine nucleotide-releasing factor RalGPS2ral GEF with PH domain and SH3-binding motif 2ralA exchange factor RalGPS2
	Modification date	20220424
	UniProtAcc	Q9ERD6

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ralgps2	GO:0005085	guanyl-nucleotide exchange factor activity	21873635	Function
Ralgps2	GO:0005886	plasma membrane	21873635	Component
Ralgps2	GO:0007265	Ras protein signal transduction	21873635	Process
Ralgps2	GO:0043547	positive regulation of GTPase activity	21873635	Process

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Spatial pattern events for Ralgps2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ralgps2	Mouse	Brain	S2	34413515	7.18e-07
Ralgps2	Mouse	Embryo	rep_3	33188776	4.10e-10
Ralgps2	Mouse	Embryo	rep_4	33188776	1.21e-07
Ralgps2	Mouse	Embryo	rep_13	33188776	7.90e-15
Ralgps2	Mouse	Kidney	rep_5	34853151	5.09e-09
Ralgps2	Mouse	Brain	rep_1	33469025	2.43e-10
Ralgps2	Mouse	Brain	rep_2	35027729	1.92e-08
Ralgps2	Mouse	Brain	rep_3	35027729	3.73e-06
Ralgps2	Mouse	Brain	rep_5	35027729	1.66e-09
Ralgps2	Mouse	Testicle	rep_3	34731600	1.09e-13
Ralgps2	Mouse	Testicle	rep_4	34731600	1.63e-15
Ralgps2	Mouse	Lymph	MS-1	0	2.71e-14
Ralgps2	Mouse	Lymph	MS-2	0	2.69e-14
Ralgps2	Mouse	Lymph	PBS	0	3.34e-14
Ralgps2	Mouse	Lung	rep_3	35290801	2.26e-06
Ralgps2	Mouse	Brain	rep_7	35210624	1.13e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Ralgps2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ralgps2	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Ralgps2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Spinal cord	L8CN17_E1	6.9e-06
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_27	3.9e-05
Ralgps2	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_27	6.4e-05
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_1	1.1e-11
Ralgps2	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.2e-13
Ralgps2	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.1e-22
Ralgps2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Ralgps2	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_3	8.3e-130
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Ralgps2	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	3.5e-92
Ralgps2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Ralgps2	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	4.4e-65
Ralgps2	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.0e-93
Ralgps2	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.2e-75
Ralgps2	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Liver	CN16-D2	1.3e-07
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	1.1e-08
Ralgps2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Ralgps2	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	3.8e-08
Ralgps2	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Lymph	MS-1	3.5e-10
Ralgps2	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_4	1.0e-16
Ralgps2	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_4	6.8e-16
Ralgps2	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_ad_rep7	4.6e-08
Ralgps2	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	7.2e-09
Ralgps2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Ralgps2	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	4.3e-10
Ralgps2	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_polb_rep9	5.2e-07

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Ralgps2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ralgps2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ralgps2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ralgps2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ralgps2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source