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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Slain2 (spascer ID:75991)

Gene summary for Slain2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Slain2

Gene ID

75991

Gene nameSLAIN motif family, member 2
Synonyms5033405K12Rik|8030444K12Rik|AI596370
Cytomap5|5 C3.2
Type of geneprotein-coding
DescriptionSLAIN motif-containing protein 2
Modification date20220424
UniProtAcc

Q8CI08


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Slain2

GO:0007020

microtubule nucleation

21873635

Process
Slain2

GO:0031116

positive regulation of microtubule polymerization

21873635

Process
Slain2

GO:0031122

cytoplasmic microtubule organization

21873635

Process
Slain2

GO:0035371

microtubule plus-end

21873635

Component

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Spatial pattern events for Slain2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Slain2MouseBrainS3 344135157.43e-06
Slain2MouseBrainS4 344135153.67e-06
Slain2MouseBrainrep_2 351413746.63e-11
Slain2MouseKidneyCLP 340037976.92e-15
Slain2MouseBrainrep_1 334690252.03e-13
Slain2MouseBrainrep_3 350277293.31e-06

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_2_H&E
boxplot
boxplot
Kidney_CLP_H&E
boxplot
boxplot
Brain_rep_1_H&E
boxplot
Brain_rep_3_H&E
boxplot
boxplot


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Spatial pattern pathway has Slain2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Slain2GOBP_Microtubule_Based_ProcessMouseSpinal cordCN94_E1 2.4e-06
Slain2GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseSpinal cordCN94_E1 4.2e-06
Slain2GOBP_Cytoskeleton_OrganizationMouseSpinal cordL7bCN02_E1 8.3e-06
Slain2GOBP_Cytoplasmic_Microtubule_OrganizationMouseSpinal cordL7CN45_C1 3.5e-07
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseSpinal cordL7CN45_C1 4.1e-06
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_OrganizationMouseSpinal cordL7CN45_C1 3.0e-06
Slain2GOBP_Positive_Regulation_Of_Cytoskeleton_OrganizationMouseSpinal cordL7CN45_C1 4.5e-06
Slain2GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseSpinal cordL7CN45_C1 6.7e-06
Slain2GOBP_Regulation_Of_Microtubule_Based_ProcessMouseSpinal cordL7CN45_C1 1.5e-07
Slain2GOBP_Regulation_Of_Microtubule_Cytoskeleton_OrganizationMouseSpinal cordL7CN45_C1 8.1e-06
Slain2GOBP_Regulation_Of_Microtubule_PolymerizationMouseSpinal cordL7CN45_C1 4.5e-06
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseBrainrep_27 1.1e-05
Slain2GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainrep_41 1.9e-07
Slain2GOBP_Regulation_Of_Microtubule_PolymerizationMouseBrainrep_41 6.9e-09
Slain2GOBP_Cytoplasmic_Microtubule_OrganizationMouseBrainrep_1 3.2e-09
Slain2GOBP_Cytoskeleton_OrganizationMouseBrainrep_1 1.1e-11
Slain2GOBP_Microtubule_Based_ProcessMouseBrainrep_1 1.6e-07
Slain2GOBP_Microtubule_NucleationMouseBrainrep_1 3.3e-40
Slain2GOBP_Microtubule_PolymerizationMouseBrainrep_1 2.7e-31
Slain2GOBP_Microtubule_Polymerization_Or_DepolymerizationMouseBrainrep_1 6.8e-20
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseBrainrep_1 3.6e-13
Slain2GOBP_Positive_Regulation_Of_Cytoskeleton_OrganizationMouseBrainrep_1 4.4e-36
Slain2GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainrep_1 3.0e-21
Slain2GOBP_Positive_Regulation_Of_Organelle_OrganizationMouseBrainrep_1 2.2e-17
Slain2GOBP_Positive_Regulation_Of_Protein_PolymerizationMouseBrainrep_1 1.1e-29
Slain2GOBP_Protein_PolymerizationMouseBrainrep_1 3.4e-38
Slain2GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseBrainrep_1 1.3e-27
Slain2GOBP_Regulation_Of_Cytoskeleton_OrganizationMouseBrainrep_1 1.1e-40
Slain2GOBP_Regulation_Of_Microtubule_Based_ProcessMouseBrainrep_1 2.0e-17
Slain2GOBP_Regulation_Of_Microtubule_Cytoskeleton_OrganizationMouseBrainrep_1 4.8e-24
Slain2GOBP_Regulation_Of_Microtubule_PolymerizationMouseBrainrep_1 1.3e-26
Slain2GOBP_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainrep_1 7.9e-26
Slain2GOBP_Regulation_Of_Organelle_OrganizationMouseBrainrep_1 7.9e-20
Slain2GOBP_Regulation_Of_Protein_Containing_Complex_AssemblyMouseBrainrep_1 1.2e-11
Slain2GOBP_Regulation_Of_Protein_PolymerizationMouseBrainrep_1 2.6e-38
Slain2GOBP_Regulation_Of_Supramolecular_Fiber_OrganizationMouseBrainrep_1 3.5e-07
Slain2GOBP_Microtubule_Cytoskeleton_OrganizationMouseBrainrep_38.5e-140
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_OrganizationMouseBrainrep_3 7.0e-65
Slain2GOBP_Positive_Regulation_Of_Protein_Containing_Complex_AssemblyMouseBrainrep_35.8e-122
Slain2GOBP_Supramolecular_Fiber_OrganizationMouseBrainrep_3 6.7e-78
Slain2GOBP_Cytoplasmic_Microtubule_OrganizationMouseEmbryorep_14 1.6e-07
Slain2GOBP_Microtubule_NucleationMouseEmbryorep_14 6.0e-09
Slain2GOBP_Regulation_Of_Cytoskeleton_OrganizationMouseEmbryorep_1 2.6e-63
Slain2GOBP_Regulation_Of_Supramolecular_Fiber_OrganizationMouseEmbryorep_11.3e-102
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_OrganizationMouseEmbryorep_2 2.3e-14
Slain2GOBP_Regulation_Of_Organelle_OrganizationMouseEmbryorep_3 1.3e-27
Slain2GOBP_Supramolecular_Fiber_OrganizationMouseEmbryorep_3 0.0e+00
Slain2GOBP_Regulation_Of_Microtubule_Based_ProcessMouseEmbryorep_54.2e-125
Slain2GOBP_Regulation_Of_Microtubule_Cytoskeleton_OrganizationMouseEmbryorep_54.2e-125
Slain2GOBP_Cytoplasmic_Microtubule_OrganizationMouseKidneyrep_2 9.7e-54
Slain2GOBP_Cytoskeleton_OrganizationMouseKidneyrep_2 1.5e-44
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseKidneyrep_2 2.9e-38
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_OrganizationMouseKidneyrep_2 2.4e-38
Slain2GOBP_Positive_Regulation_Of_Organelle_OrganizationMouseKidneyrep_2 4.1e-12
Slain2GOBP_Positive_Regulation_Of_Protein_Containing_Complex_AssemblyMouseKidneyrep_2 5.6e-19
Slain2GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseKidneyrep_2 8.3e-40
Slain2GOBP_Regulation_Of_Cytoskeleton_OrganizationMouseKidneyrep_2 1.8e-22
Slain2GOBP_Regulation_Of_Organelle_OrganizationMouseKidneyrep_2 6.7e-77
Slain2GOBP_Regulation_Of_Protein_Containing_Complex_AssemblyMouseKidneyrep_2 1.8e-14
Slain2GOBP_Regulation_Of_Supramolecular_Fiber_OrganizationMouseKidneyrep_2 9.1e-54
Slain2GOBP_Supramolecular_Fiber_OrganizationMouseKidneyrep_2 9.5e-65
Slain2GOBP_Microtubule_Based_ProcessMouseLiverCN16-D2 1.8e-11
Slain2GOBP_Microtubule_Cytoskeleton_OrganizationMouseLiverCN16-D2 2.8e-10
Slain2GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseLiverCN16-E1 3.5e-08
Slain2GOBP_Microtubule_NucleationMouseLiverCN65-C1 8.5e-12
Slain2GOBP_Microtubule_Polymerization_Or_DepolymerizationMouseLiverCN65-C1 6.4e-09
Slain2GOBP_Microtubule_NucleationMouseLiverrep_16 1.1e-11
Slain2GOBP_Microtubule_Polymerization_Or_DepolymerizationMouseLiverrep_16 7.4e-11
Slain2GOBP_Protein_PolymerizationMouseLiverrep_16 3.0e-07
Slain2GOBP_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseLiverrep_16 7.8e-13
Slain2GOBP_Cytoplasmic_Microtubule_OrganizationMouseLymphMS-1 1.8e-18
Slain2GOBP_Cytoskeleton_OrganizationMouseLymphMS-1 1.8e-13
Slain2GOBP_Microtubule_Based_ProcessMouseLymphMS-1 1.5e-08
Slain2GOBP_Microtubule_Cytoskeleton_OrganizationMouseLymphMS-1 7.6e-07
Slain2GOBP_Microtubule_PolymerizationMouseLymphMS-1 5.1e-08
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseLymphMS-1 3.6e-08
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_OrganizationMouseLymphMS-1 1.8e-09
Slain2GOBP_Positive_Regulation_Of_Cytoskeleton_OrganizationMouseLymphMS-1 5.5e-09
Slain2GOBP_Positive_Regulation_Of_Organelle_OrganizationMouseLymphMS-1 2.8e-08
Slain2GOBP_Positive_Regulation_Of_Protein_Containing_Complex_AssemblyMouseLymphMS-1 3.6e-08
Slain2GOBP_Positive_Regulation_Of_Protein_PolymerizationMouseLymphMS-1 1.5e-11
Slain2GOBP_Protein_PolymerizationMouseLymphMS-1 8.7e-08
Slain2GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseLymphMS-1 2.2e-09
Slain2GOBP_Regulation_Of_Cytoskeleton_OrganizationMouseLymphMS-1 8.4e-09
Slain2GOBP_Regulation_Of_Organelle_OrganizationMouseLymphMS-1 1.4e-10
Slain2GOBP_Regulation_Of_Protein_Containing_Complex_AssemblyMouseLymphMS-1 2.3e-12
Slain2GOBP_Regulation_Of_Protein_PolymerizationMouseLymphMS-1 5.2e-09
Slain2GOBP_Regulation_Of_Supramolecular_Fiber_OrganizationMouseLymphMS-1 4.3e-11
Slain2GOBP_Supramolecular_Fiber_OrganizationMouseLymphMS-1 1.5e-12
Slain2GOBP_Regulation_Of_Microtubule_PolymerizationMouseLymphMS-2 6.7e-07
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseBrainrep_4 1.5e-12
Slain2GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainrep_4 1.4e-24
Slain2GOBP_Regulation_Of_Microtubule_Based_ProcessMouseBrainrep_4 2.3e-16
Slain2GOBP_Regulation_Of_Microtubule_Cytoskeleton_OrganizationMouseBrainrep_4 2.6e-09
Slain2GOBP_Regulation_Of_Microtubule_PolymerizationMouseBrainrep_4 8.4e-13
Slain2GOBP_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainrep_4 3.0e-27
Slain2GOBP_Cytoplasmic_Microtubule_OrganizationMouseBrainHP_ad_rep7 1.3e-15
Slain2GOBP_Cytoskeleton_OrganizationMouseBrainHP_ad_rep7 5.3e-08
Slain2GOBP_Microtubule_Based_ProcessMouseBrainHP_ad_rep7 2.8e-10
Slain2GOBP_Microtubule_Cytoskeleton_OrganizationMouseBrainHP_ad_rep7 3.8e-13
Slain2GOBP_Microtubule_NucleationMouseBrainHP_ad_rep7 1.9e-21
Slain2GOBP_Microtubule_PolymerizationMouseBrainHP_ad_rep7 6.4e-15
Slain2GOBP_Microtubule_Polymerization_Or_DepolymerizationMouseBrainHP_ad_rep7 7.6e-16
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_BiogenesisMouseBrainHP_ad_rep7 1.7e-11
Slain2GOBP_Positive_Regulation_Of_Cellular_Component_OrganizationMouseBrainHP_ad_rep7 2.0e-07
Slain2GOBP_Positive_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainHP_ad_rep7 2.1e-14
Slain2GOBP_Positive_Regulation_Of_Organelle_OrganizationMouseBrainHP_ad_rep7 3.5e-08
Slain2GOBP_Positive_Regulation_Of_Protein_Containing_Complex_AssemblyMouseBrainHP_ad_rep7 9.6e-09
Slain2GOBP_Positive_Regulation_Of_Protein_PolymerizationMouseBrainHP_ad_rep7 2.7e-08
Slain2GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseBrainHP_ad_rep7 6.5e-10
Slain2GOBP_Regulation_Of_Microtubule_Based_ProcessMouseBrainHP_ad_rep7 3.2e-13
Slain2GOBP_Regulation_Of_Microtubule_Cytoskeleton_OrganizationMouseBrainHP_ad_rep7 8.7e-15
Slain2GOBP_Regulation_Of_Microtubule_PolymerizationMouseBrainHP_ad_rep7 2.9e-18
Slain2GOBP_Regulation_Of_Microtubule_Polymerization_Or_DepolymerizationMouseBrainHP_ad_rep7 5.7e-18
Slain2GOBP_Regulation_Of_Organelle_OrganizationMouseBrainHP_ad_rep7 8.1e-07
Slain2GOBP_Regulation_Of_Protein_Containing_Complex_AssemblyMouseBrainHP_ad_rep7 1.6e-08
Slain2GOBP_Supramolecular_Fiber_OrganizationMouseBrainHP_ad_rep7 5.2e-07
Slain2GOBP_Positive_Regulation_Of_Cytoskeleton_OrganizationMouseBrainHP_polb_rep9 5.5e-09
Slain2GOBP_Protein_PolymerizationMouseBrainHP_polb_rep9 5.9e-08
Slain2GOBP_Regulation_Of_Cytoskeleton_OrganizationMouseBrainHP_polb_rep9 1.1e-07

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Slain2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Slain2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Slain2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Slain2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Slain2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource