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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Spaca6 (spascer ID:75202)

Gene summary for Spaca6

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Spaca6

Gene ID

75202

Gene namesperm acrosome associated 6
Synonyms4930546H06Rik|9530079D04Rik|B230206P06Rik|Ncrna00085|SPACA6A|let-7e|mir-125a|mir-99b
Cytomap17|17 A3.2
Type of geneprotein-coding
Descriptionsperm acrosome membrane-associated protein 6immunoglobulin domain-containing protein
Modification date20220424
UniProtAcc

E9Q8Q8


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Spaca6

GO:0007342

fusion of sperm to egg plasma membrane involved in single fertilization

21873635

Process

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Spatial pattern events for Spaca6

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Spaca6MouseBrainS2 344135153.82e-09
Spaca6MouseEmbryorep_1 331887762.41e-06
Spaca6MouseEmbryorep_13 331887762.15e-06
Spaca6MouseKidneyCLP 340037976.61e-06
Spaca6MouseKidneyIRI 340037977.37e-15
Spaca6MouseTesticlerep_6 347316008.31e-13
Spaca6MouseLymphA1 06.42e-11
Spaca6MouseLymphB1 01.11e-09

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_CLP_H&E
boxplot

boxplot
Kidney_IRI_H&E
boxplot

boxplot


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Spatial pattern pathway has Spaca6 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Spaca6GOBP_ReproductionMouseSpinal cordCN94_E1 7.8e-08
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseSpinal cordL7CN45_C1 8.6e-09
Spaca6GOBP_FertilizationMouseSpinal cordL7CN45_C1 3.0e-07
Spaca6GOBP_Membrane_OrganizationMouseSpinal cordL7CN45_C1 2.7e-07
Spaca6GOBP_Multicellular_Organism_ReproductionMouseSpinal cordL7CN45_C1 7.1e-07
Spaca6GOBP_Plasma_Membrane_FusionMouseSpinal cordL7CN45_C1 1.7e-08
Spaca6GOBP_Single_FertilizationMouseSpinal cordL7CN45_C1 1.0e-07
Spaca6GOBP_Fusion_Of_Sperm_To_Egg_Plasma_Membrane_Involved_In_Single_FertilizationMouseSpinal cordL7CN45_C2 4.2e-08
Spaca6GOBP_Membrane_FusionMouseSpinal cordL7CN47_C1 4.7e-06
Spaca6GOBP_Plasma_Membrane_FusionMouseBrainrep_75 2.5e-05
Spaca6GOBP_Membrane_FusionMouseBrainrep_1 3.8e-47
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseBrainrep_33.6e-171
Spaca6GOBP_FertilizationMouseBrainrep_37.5e-151
Spaca6GOBP_Membrane_OrganizationMouseBrainrep_3 1.9e-41
Spaca6GOBP_Multicellular_Organism_ReproductionMouseBrainrep_3 1.2e-58
Spaca6GOBP_Plasma_Membrane_FusionMouseBrainrep_3 2.2e-11
Spaca6GOBP_ReproductionMouseBrainrep_33.4e-125
Spaca6GOBP_Single_FertilizationMouseBrainrep_33.9e-152
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseEmbryorep_14 4.3e-09
Spaca6GOBP_FertilizationMouseEmbryorep_14 8.1e-31
Spaca6GOBP_Multicellular_Organism_ReproductionMouseEmbryorep_14 5.9e-07
Spaca6GOBP_Single_FertilizationMouseEmbryorep_14 4.1e-52
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseEmbryorep_3 6.9e-27
Spaca6GOBP_Multicellular_Organism_ReproductionMouseEmbryorep_38.7e-222
Spaca6GOBP_Membrane_FusionMouseEmbryorep_5 2.5e-16
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseKidneyrep_2 1.1e-18
Spaca6GOBP_FertilizationMouseKidneyrep_2 2.2e-43
Spaca6GOBP_Fusion_Of_Sperm_To_Egg_Plasma_Membrane_Involved_In_Single_FertilizationMouseKidneyrep_2 1.7e-92
Spaca6GOBP_Membrane_FusionMouseKidneyrep_23.4e-106
Spaca6GOBP_Membrane_OrganizationMouseKidneyrep_2 8.5e-74
Spaca6GOBP_Multicellular_Organism_ReproductionMouseKidneyrep_2 1.6e-53
Spaca6GOBP_Plasma_Membrane_FusionMouseKidneyrep_21.7e-115
Spaca6GOBP_ReproductionMouseKidneyrep_2 9.0e-46
Spaca6GOBP_Single_FertilizationMouseKidneyrep_2 2.3e-57
Spaca6GOBP_Fusion_Of_Sperm_To_Egg_Plasma_Membrane_Involved_In_Single_FertilizationMouseKidneyrep_3 3.2e-05
Spaca6GOBP_Single_FertilizationMouseLiverCN16-E1 1.2e-09
Spaca6GOBP_Fusion_Of_Sperm_To_Egg_Plasma_Membrane_Involved_In_Single_FertilizationMouseLiverCN73-C1 4.4e-07
Spaca6GOBP_Plasma_Membrane_FusionMouseLiverCN73-C1 5.1e-08
Spaca6GOBP_Fusion_Of_Sperm_To_Egg_Plasma_Membrane_Involved_In_Single_FertilizationMouseLiverrep_17 5.8e-17
Spaca6GOBP_Plasma_Membrane_FusionMouseLiverrep_17 2.7e-19
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseLymphMS-1 2.1e-08
Spaca6GOBP_FertilizationMouseLymphMS-1 1.2e-08
Spaca6GOBP_Membrane_OrganizationMouseLymphMS-1 5.8e-20
Spaca6GOBP_Multicellular_Organism_ReproductionMouseLymphMS-1 1.1e-09
Spaca6GOBP_ReproductionMouseLymphMS-1 1.1e-09
Spaca6GOBP_Single_FertilizationMouseLymphMS-1 2.3e-09
Spaca6GOBP_ReproductionMouseLungrep_1 9.6e-12
Spaca6GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_OrganismMouseBrainHP_ad_rep7 6.0e-15
Spaca6GOBP_FertilizationMouseBrainHP_ad_rep7 4.9e-08
Spaca6GOBP_Multicellular_Organism_ReproductionMouseBrainHP_ad_rep7 6.1e-08
Spaca6GOBP_ReproductionMouseBrainHP_ad_rep7 7.9e-09
Spaca6GOBP_Single_FertilizationMouseBrainHP_ad_rep7 7.1e-10
Spaca6GOBP_Membrane_FusionMouseBrainHP_polb_rep9 6.9e-14
Spaca6GOBP_Membrane_OrganizationMouseBrainHP_polb_rep9 1.4e-13
Spaca6GOBP_Plasma_Membrane_FusionMouseBrainHP_polb_rep9 5.9e-08

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Spaca6 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Spaca6 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Spaca6 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Spaca6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Spaca6

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource