SPASCER Logo

Home

Download & Upload

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Wipi2 (spascer ID:74781)

Gene summary for Wipi2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Wipi2

Gene ID

74781

Gene nameWD repeat domain, phosphoinositide interacting 2
Synonyms1110018O08Rik|2510001I10Rik
Cytomap5|5 G2
Type of geneprotein-coding
DescriptionWD repeat domain phosphoinositide-interacting protein 2WIPI-2
Modification date20220424
UniProtAcc

Q80W47


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Wipi2

GO:0000422

autophagy of mitochondrion

21873635

Process
Wipi2

GO:0005829

cytosol

21873635

Component
Wipi2

GO:0006497

protein lipidation

21873635

Process
Wipi2

GO:0019898

extrinsic component of membrane

21873635

Component
Wipi2

GO:0032266

phosphatidylinositol-3-phosphate binding

21873635

Function
Wipi2

GO:0034045

phagophore assembly site membrane

21873635

Component
Wipi2

GO:0034497

protein localization to phagophore assembly site

21873635

Process
Wipi2

GO:0044804

autophagy of nucleus

21873635

Process
Wipi2

GO:0080025

phosphatidylinositol-3,5-bisphosphate binding

21873635

Function

Top

Spatial pattern events for Wipi2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Wipi2MouseBrainS1 344135153.31e-08
Wipi2MouseBrainS2 344135156.26e-06
Wipi2MouseBrainS3 344135151.64e-15
Wipi2MouseBrainrep_1 351413743.64e-06
Wipi2MouseBrainrep_6 351413741.28e-06
Wipi2MouseKidneyIRI 340037972.29e-15
Wipi2MouseKidneySham 340037976.79e-11
Wipi2MouseKidneyrep_3 348531511.87e-06
Wipi2MouseBrainrep_3 350277293.50e-07
Wipi2MouseIntestinerep_4 351497213.57e-07
Wipi2MouseTesticlerep_5 347316001.06e-14
Wipi2MouseLymphA1 04.99e-10
Wipi2MouseBrainrep_1 352106246.11e-07

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
boxplot
boxplot
Brain_rep_6_H&E
boxplot
boxplot
Kidney_IRI_H&E
boxplot
boxplot
Kidney_Sham_H&E
boxplot
boxplot
Kidney_rep_3_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot


Top

Spatial pattern pathway has Wipi2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseSpinal cordCN94_E1 9.3e-06
Wipi2GOBP_Lipoprotein_Biosynthetic_ProcessMouseSpinal cordCN94_E1 7.5e-07
Wipi2GOBP_Organelle_AssemblyMouseSpinal cordCN94_E1 9.5e-06
Wipi2GOBP_Selective_AutophagyMouseSpinal cordCN94_E1 2.4e-06
Wipi2GOBP_Autophagosome_OrganizationMouseSpinal cordL7bCN02_E1 5.0e-06
Wipi2GOBP_Autophagy_Of_MitochondrionMouseSpinal cordL7CN45_C1 1.2e-07
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseSpinal cordL7CN45_C1 4.7e-06
Wipi2GOBP_Cellular_Component_DisassemblyMouseSpinal cordL7CN45_C1 1.0e-06
Wipi2GOBP_Cellular_Macromolecule_LocalizationMouseSpinal cordL7CN45_C1 4.2e-07
Wipi2GOBP_Cellular_Response_To_External_StimulusMouseSpinal cordL7CN45_C1 2.4e-08
Wipi2GOBP_Cellular_Response_To_StarvationMouseSpinal cordL7CN45_C1 2.3e-07
Wipi2GOBP_Lipoprotein_Metabolic_ProcessMouseSpinal cordL7CN45_C1 4.0e-06
Wipi2GOBP_MacroautophagyMouseSpinal cordL7CN45_C1 1.0e-06
Wipi2GOBP_Mitochondrion_OrganizationMouseSpinal cordL7CN45_C1 3.6e-07
Wipi2GOBP_Organelle_DisassemblyMouseSpinal cordL7CN45_C1 5.6e-07
Wipi2GOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseSpinal cordL7CN45_C1 5.6e-08
Wipi2GOBP_Post_Translational_Protein_ModificationMouseSpinal cordL7CN45_C1 5.2e-06
Wipi2GOBP_Process_Utilizing_Autophagic_MechanismMouseSpinal cordL7CN45_C1 3.6e-07
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseSpinal cordL7CN45_C1 3.3e-07
Wipi2GOBP_Response_To_Extracellular_StimulusMouseSpinal cordL7CN45_C1 1.7e-07
Wipi2GOBP_Response_To_StarvationMouseSpinal cordL7CN45_C1 4.3e-07
Wipi2GOBP_C_Terminal_Protein_LipidationMouseSpinal cordL7CN47_C1 2.9e-06
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseSpinal cordL7CN97_E2 7.9e-07
Wipi2GOBP_Defense_ResponseMouseSpinal cordL8CN11_C1 3.3e-17
Wipi2GOBP_Autophagosome_OrganizationMouseBrainrep_27 9.0e-05
Wipi2GOBP_Cellular_Response_To_StarvationMouseBrainrep_27 1.3e-05
Wipi2GOBP_Response_To_StarvationMouseBrainrep_27 7.4e-08
Wipi2GOBP_C_Terminal_Protein_LipidationMouseBrainrep_41 9.3e-07
Wipi2GOBP_Autophagy_Of_NucleusMouseBrainrep_1 4.6e-30
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseBrainrep_1 3.0e-50
Wipi2GOBP_C_Terminal_Protein_LipidationMouseBrainrep_1 1.2e-46
Wipi2GOBP_Cellular_Component_DisassemblyMouseBrainrep_1 1.5e-15
Wipi2GOBP_MacroautophagyMouseBrainrep_1 6.7e-14
Wipi2GOBP_Autophagosome_OrganizationMouseBrainrep_35.9e-105
Wipi2GOBP_Autophagy_Of_MitochondrionMouseBrainrep_32.1e-106
Wipi2GOBP_Cellular_Macromolecule_LocalizationMouseBrainrep_31.6e-125
Wipi2GOBP_Cellular_Response_To_External_StimulusMouseBrainrep_3 1.9e-53
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseBrainrep_3 5.2e-44
Wipi2GOBP_Cellular_Response_To_StarvationMouseBrainrep_31.1e-148
Wipi2GOBP_Defense_ResponseMouseBrainrep_3 8.7e-77
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseBrainrep_36.0e-105
Wipi2GOBP_Lipoprotein_Biosynthetic_ProcessMouseBrainrep_3 1.8e-58
Wipi2GOBP_Lipoprotein_Metabolic_ProcessMouseBrainrep_3 4.0e-92
Wipi2GOBP_Mitochondrion_OrganizationMouseBrainrep_3 1.3e-89
Wipi2GOBP_Organelle_AssemblyMouseBrainrep_32.0e-160
Wipi2GOBP_Organelle_DisassemblyMouseBrainrep_3 2.0e-93
Wipi2GOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseBrainrep_32.9e-144
Wipi2GOBP_Post_Translational_Protein_ModificationMouseBrainrep_36.2e-128
Wipi2GOBP_Process_Utilizing_Autophagic_MechanismMouseBrainrep_31.0e-145
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseBrainrep_31.2e-154
Wipi2GOBP_Response_To_Extracellular_StimulusMouseBrainrep_32.2e-117
Wipi2GOBP_Response_To_StarvationMouseBrainrep_35.8e-139
Wipi2GOBP_Selective_AutophagyMouseBrainrep_3 6.0e-85
Wipi2GOBP_Vacuole_OrganizationMouseBrainrep_39.7e-150
Wipi2GOBP_XenophagyMouseBrainrep_3 1.8e-46
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseEmbryorep_6 2.2e-07
Wipi2GOBP_Autophagy_Of_MitochondrionMouseEmbryorep_14 2.1e-07
Wipi2GOBP_Autophagy_Of_NucleusMouseEmbryorep_14 3.5e-69
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseEmbryorep_14 1.2e-54
Wipi2GOBP_C_Terminal_Protein_LipidationMouseEmbryorep_14 2.2e-29
Wipi2GOBP_Lipoprotein_Biosynthetic_ProcessMouseEmbryorep_14 9.7e-11
Wipi2GOBP_Mitochondrion_OrganizationMouseEmbryorep_14 1.8e-11
Wipi2GOBP_Organelle_DisassemblyMouseEmbryorep_14 2.6e-21
Wipi2GOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseEmbryorep_14 2.4e-12
Wipi2GOBP_Post_Translational_Protein_ModificationMouseEmbryorep_14 1.7e-45
Wipi2GOBP_Selective_AutophagyMouseEmbryorep_14 1.9e-17
Wipi2GOBP_XenophagyMouseEmbryorep_14 1.3e-45
Wipi2GOBP_Cellular_Response_To_External_StimulusMouseEmbryorep_1 2.1e-63
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseEmbryorep_1 1.7e-07
Wipi2GOBP_Defense_ResponseMouseEmbryorep_1 5.2e-63
Wipi2GOBP_Cellular_Macromolecule_LocalizationMouseEmbryorep_2 5.5e-15
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseEmbryorep_32.6e-164
Wipi2GOBP_Mitochondrion_OrganizationMouseEmbryorep_3 4.0e-48
Wipi2GOBP_Response_To_Extracellular_StimulusMouseEmbryorep_4 1.2e-08
Wipi2GOBP_Lipoprotein_Metabolic_ProcessMouseEmbryorep_66.1e-112
Wipi2GOBP_Organelle_AssemblyMouseEmbryorep_6 4.1e-70
Wipi2GOBP_Autophagosome_OrganizationMouseKidneyrep_2 5.0e-88
Wipi2GOBP_Autophagy_Of_MitochondrionMouseKidneyrep_2 1.9e-41
Wipi2GOBP_Autophagy_Of_NucleusMouseKidneyrep_2 5.8e-29
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseKidneyrep_2 7.0e-67
Wipi2GOBP_C_Terminal_Protein_LipidationMouseKidneyrep_2 1.0e-19
Wipi2GOBP_Cellular_Component_DisassemblyMouseKidneyrep_2 4.2e-70
Wipi2GOBP_Cellular_Macromolecule_LocalizationMouseKidneyrep_2 3.5e-61
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseKidneyrep_2 1.6e-13
Wipi2GOBP_Cellular_Response_To_StarvationMouseKidneyrep_2 4.8e-18
Wipi2GOBP_Defense_ResponseMouseKidneyrep_26.8e-127
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseKidneyrep_22.3e-129
Wipi2GOBP_Lipoprotein_Biosynthetic_ProcessMouseKidneyrep_24.8e-139
Wipi2GOBP_Lipoprotein_Metabolic_ProcessMouseKidneyrep_21.0e-163
Wipi2GOBP_MacroautophagyMouseKidneyrep_2 1.3e-64
Wipi2GOBP_Mitochondrion_OrganizationMouseKidneyrep_2 1.7e-21
Wipi2GOBP_Organelle_AssemblyMouseKidneyrep_2 2.8e-62
Wipi2GOBP_Organelle_DisassemblyMouseKidneyrep_2 1.2e-56
Wipi2GOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseKidneyrep_2 8.9e-78
Wipi2GOBP_Post_Translational_Protein_ModificationMouseKidneyrep_2 7.2e-84
Wipi2GOBP_Process_Utilizing_Autophagic_MechanismMouseKidneyrep_2 1.8e-66
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseKidneyrep_2 1.7e-18
Wipi2GOBP_Response_To_Extracellular_StimulusMouseKidneyrep_2 3.8e-52
Wipi2GOBP_Response_To_StarvationMouseKidneyrep_2 1.3e-11
Wipi2GOBP_Selective_AutophagyMouseKidneyrep_2 1.9e-18
Wipi2GOBP_Vacuole_OrganizationMouseKidneyrep_2 2.6e-92
Wipi2GOBP_XenophagyMouseKidneyrep_2 2.4e-50
Wipi2GOBP_C_Terminal_Protein_LipidationMouseLiverCN16-D1 5.0e-11
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseLiverCN16-D1 9.5e-10
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseLiverCN16-D2 2.0e-09
Wipi2GOBP_Autophagy_Of_NucleusMouseLiverCN65-C1 8.5e-09
Wipi2GOBP_XenophagyMouseLiverCN65-C1 2.9e-07
Wipi2GOBP_Post_Translational_Protein_ModificationMouseLiverCN73-C1 9.0e-07
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseLiverrep_15 1.2e-07
Wipi2GOBP_C_Terminal_Protein_LipidationMouseLiverrep_15 1.0e-16
Wipi2GOBP_XenophagyMouseLiverrep_15 4.5e-11
Wipi2GOBP_Cellular_Response_To_External_StimulusMouseLiverrep_16 6.3e-14
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseLiverrep_16 4.1e-17
Wipi2GOBP_Cellular_Response_To_StarvationMouseLiverrep_16 1.1e-15
Wipi2GOBP_Defense_ResponseMouseLiverrep_16 8.0e-16
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseLiverrep_16 1.8e-13
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseLiverrep_16 8.0e-08
Wipi2GOBP_Response_To_Extracellular_StimulusMouseLiverrep_16 8.0e-26
Wipi2GOBP_Response_To_StarvationMouseLiverrep_16 9.4e-25
Wipi2GOBP_C_Terminal_Protein_LipidationMouseBrainrep_1 3.9e-09
Wipi2GOBP_Autophagosome_OrganizationMouseLymphMS-1 3.1e-11
Wipi2GOBP_Autophagy_Of_MitochondrionMouseLymphMS-1 4.2e-14
Wipi2GOBP_Autophagy_Of_NucleusMouseLymphMS-1 1.4e-07
Wipi2GOBP_Cellular_Component_DisassemblyMouseLymphMS-1 2.4e-16
Wipi2GOBP_Cellular_Macromolecule_LocalizationMouseLymphMS-1 1.1e-11
Wipi2GOBP_Cellular_Response_To_External_StimulusMouseLymphMS-1 4.4e-13
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseLymphMS-1 1.6e-14
Wipi2GOBP_Cellular_Response_To_StarvationMouseLymphMS-1 7.4e-11
Wipi2GOBP_Defense_ResponseMouseLymphMS-1 8.6e-18
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseLymphMS-1 6.7e-20
Wipi2GOBP_Lipoprotein_Biosynthetic_ProcessMouseLymphMS-1 6.0e-07
Wipi2GOBP_Lipoprotein_Metabolic_ProcessMouseLymphMS-1 3.6e-09
Wipi2GOBP_MacroautophagyMouseLymphMS-1 3.3e-11
Wipi2GOBP_Mitochondrion_OrganizationMouseLymphMS-1 4.2e-09
Wipi2GOBP_Organelle_AssemblyMouseLymphMS-1 5.5e-08
Wipi2GOBP_Organelle_DisassemblyMouseLymphMS-1 5.9e-12
Wipi2GOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseLymphMS-1 1.4e-09
Wipi2GOBP_Process_Utilizing_Autophagic_MechanismMouseLymphMS-1 3.9e-13
Wipi2GOBP_Response_To_Extracellular_StimulusMouseLymphMS-1 1.1e-12
Wipi2GOBP_Response_To_StarvationMouseLymphMS-1 1.7e-10
Wipi2GOBP_Post_Translational_Protein_ModificationMouseLymphPBS 6.0e-07
Wipi2GOBP_Autophagy_Of_NucleusMouseBrainrep_4 9.8e-27
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseBrainrep_4 5.4e-21
Wipi2GOBP_C_Terminal_Protein_LipidationMouseBrainrep_4 1.7e-27
Wipi2GOBP_XenophagyMouseBrainrep_4 3.3e-24
Wipi2GOBP_Cellular_Response_To_StarvationMouseBrainrep_7 1.9e-09
Wipi2GOBP_Organelle_DisassemblyMouseBrainrep_7 4.5e-11
Wipi2GOBP_Response_To_StarvationMouseBrainrep_7 5.6e-09
Wipi2GOBP_Autophagy_Of_NucleusMouseBrainHP_ad_rep3 7.5e-08
Wipi2GOBP_C_Terminal_Protein_LipidationMouseBrainHP_ad_rep3 1.3e-16
Wipi2GOBP_C_Terminal_Protein_Amino_Acid_ModificationMouseBrainHP_ad_rep7 1.4e-12
Wipi2GOBP_Cellular_Macromolecule_LocalizationMouseBrainHP_ad_rep7 6.6e-10
Wipi2GOBP_Cellular_Response_To_StarvationMouseBrainHP_ad_rep7 3.0e-14
Wipi2GOBP_Defense_ResponseMouseBrainHP_ad_rep7 5.6e-10
Wipi2GOBP_Lipoprotein_Biosynthetic_ProcessMouseBrainHP_ad_rep7 3.0e-07
Wipi2GOBP_MacroautophagyMouseBrainHP_ad_rep7 1.6e-07
Wipi2GOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseBrainHP_ad_rep7 2.8e-08
Wipi2GOBP_Process_Utilizing_Autophagic_MechanismMouseBrainHP_ad_rep7 3.5e-08
Wipi2GOBP_Protein_Localization_To_Phagophore_Assembly_SiteMouseBrainHP_ad_rep7 7.3e-09
Wipi2GOBP_Response_To_Extracellular_StimulusMouseBrainHP_ad_rep7 1.4e-09
Wipi2GOBP_Response_To_StarvationMouseBrainHP_ad_rep7 4.4e-12
Wipi2GOBP_XenophagyMouseBrainHP_ad_rep7 8.8e-08
Wipi2GOBP_Organelle_AssemblyMouseBrainHP_adpolb_rep1 1.8e-07
Wipi2GOBP_Autophagosome_OrganizationMouseBrainHP_polb_rep9 4.0e-09
Wipi2GOBP_Autophagy_Of_MitochondrionMouseBrainHP_polb_rep9 3.2e-12
Wipi2GOBP_Cellular_Component_DisassemblyMouseBrainHP_polb_rep9 3.4e-08
Wipi2GOBP_Cellular_Response_To_External_StimulusMouseBrainHP_polb_rep9 4.1e-14
Wipi2GOBP_Cellular_Response_To_Extracellular_StimulusMouseBrainHP_polb_rep9 1.7e-11
Wipi2GOBP_Defense_Response_To_Other_OrganismMouseBrainHP_polb_rep9 2.1e-11
Wipi2GOBP_Lipoprotein_Metabolic_ProcessMouseBrainHP_polb_rep9 2.6e-14
Wipi2GOBP_Mitochondrion_OrganizationMouseBrainHP_polb_rep9 1.2e-11
Wipi2GOBP_Organelle_DisassemblyMouseBrainHP_polb_rep9 4.4e-13
Wipi2GOBP_Post_Translational_Protein_ModificationMouseBrainHP_polb_rep9 5.1e-14
Wipi2GOBP_Selective_AutophagyMouseBrainHP_polb_rep9 7.9e-08
Wipi2GOBP_Vacuole_OrganizationMouseBrainHP_polb_rep9 9.0e-08

Top

Wipi2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

Top

Wipi2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

Top

Transcription factor for Wipi2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

Top

Related Drugs for Wipi2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for Wipi2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource