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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Hhatl (spascer ID:74770)

Gene summary for Hhatl

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Hhatl
	Gene ID	74770
	Gene name	hedgehog acyltransferase-like
	Synonyms	1110011D13Rik\|Gup1\|Mg56
	Cytomap	9\|9 F4
	Type of gene	protein-coding
	Description	protein-cysteine N-palmitoyltransferase HHAT-like proteinMitsugumin 56glycerol uptake/transporter homologhedgehog acyltransferase-like protein
	Modification date	20220424
	UniProtAcc	Q9D1G3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Hhatl	GO:0005783	endoplasmic reticulum	21873635	Component
Hhatl	GO:0016746	acyltransferase activity	21873635	Function
Hhatl	GO:0060262	negative regulation of N-terminal protein palmitoylation	21873635	Process

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Spatial pattern events for Hhatl

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Hhatl	Mouse	Brain	S2	34413515	1.56e-15
Hhatl	Mouse	Brain	S3	34413515	1.21e-11
Hhatl	Mouse	Brain	S4	34413515	1.37e-15
Hhatl	Mouse	Brain	S6	34413515	1.46e-15
Hhatl	Mouse	Brain	S7	34413515	2.85e-15
Hhatl	Mouse	Brain	rep_1	35141374	1.08e-06
Hhatl	Mouse	Brain	rep_2	35141374	1.69e-15
Hhatl	Mouse	Brain	rep_3	35141374	1.40e-12
Hhatl	Mouse	Brain	rep_4	35141374	5.42e-15
Hhatl	Mouse	Brain	rep_5	35141374	2.68e-15
Hhatl	Mouse	Kidney	CLP	34003797	3.77e-15
Hhatl	Mouse	Kidney	IRI	34003797	2.29e-15
Hhatl	Mouse	Kidney	Sham	34003797	2.58e-15
Hhatl	Mouse	Kidney	rep_1	34853151	2.42e-15
Hhatl	Mouse	Kidney	rep_3	34853151	2.94e-15
Hhatl	Mouse	Brain	rep_1	35027729	2.98e-15
Hhatl	Mouse	Brain	rep_2	35027729	1.57e-15
Hhatl	Mouse	Brain	rep_3	35027729	1.32e-15
Hhatl	Mouse	Brain	rep_4	35027729	3.48e-12
Hhatl	Mouse	Brain	rep_5	35027729	1.46e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Hhatl envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Hhatl	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	7.5e-07
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Hhatl	GOBP_Lipoprotein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.0e-06
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Spinal cord	L7CN45_C1	1.6e-08
Hhatl	GOBP_Negative_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-06
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Hhatl	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Hhatl	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Hhatl	GOBP_Protein_Acylation	Mouse	Spinal cord	L7CN45_C1	1.0e-07
Hhatl	GOBP_Protein_Palmitoylation	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Hhatl	GOBP_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.3e-11
Hhatl	GOBP_Regulation_Of_Protein_Lipidation	Mouse	Spinal cord	L7CN45_C1	7.6e-08
Hhatl	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_27	1.2e-06
Hhatl	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Mouse	Brain	rep_27	5.5e-09
Hhatl	GOBP_Protein_Acylation	Mouse	Brain	rep_72	5.8e-05
Hhatl	GOBP_N_Terminal_Protein_Amino_Acid_Modification	Mouse	Brain	rep_1	1.5e-15
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Brain	rep_1	6.0e-51
Hhatl	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Mouse	Brain	rep_1	1.2e-21
Hhatl	GOBP_Protein_Acylation	Mouse	Brain	rep_1	1.4e-26
Hhatl	GOBP_Protein_Palmitoylation	Mouse	Brain	rep_1	6.6e-22
Hhatl	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Brain	rep_3	1.8e-58
Hhatl	GOBP_Lipoprotein_Metabolic_Process	Mouse	Brain	rep_3	4.0e-92
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_3	5.5e-184
Hhatl	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Hhatl	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Brain	rep_3	2.2e-188
Hhatl	GOBP_Protein_Palmitoylation	Mouse	Embryo	rep_6	7.7e-07
Hhatl	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Embryo	rep_14	9.7e-11
Hhatl	GOBP_N_Terminal_Protein_Amino_Acid_Modification	Mouse	Embryo	rep_14	8.1e-54
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Embryo	rep_14	3.3e-63
Hhatl	GOBP_Negative_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Embryo	rep_14	7.9e-10
Hhatl	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Hhatl	GOBP_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Embryo	rep_14	8.9e-19
Hhatl	GOBP_Regulation_Of_Protein_Lipidation	Mouse	Embryo	rep_14	2.2e-27
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Hhatl	GOBP_Protein_Acylation	Mouse	Embryo	rep_3	0.0e+00
Hhatl	GOBP_N_Terminal_Protein_Amino_Acid_Modification	Mouse	Embryo	rep_4	2.5e-18
Hhatl	GOBP_Lipoprotein_Metabolic_Process	Mouse	Embryo	rep_6	6.1e-112
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	Nep	4.6e-22
Hhatl	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	Nep	4.6e-22
Hhatl	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Kidney	rep_2	4.8e-139
Hhatl	GOBP_Lipoprotein_Metabolic_Process	Mouse	Kidney	rep_2	1.0e-163
Hhatl	GOBP_N_Terminal_Protein_Amino_Acid_Modification	Mouse	Kidney	rep_2	3.1e-26
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Kidney	rep_2	6.7e-64
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Hhatl	GOBP_Negative_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Kidney	rep_2	9.3e-109
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-72
Hhatl	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	rep_2	1.4e-32
Hhatl	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Hhatl	GOBP_Protein_Acylation	Mouse	Kidney	rep_2	1.1e-58
Hhatl	GOBP_Protein_Palmitoylation	Mouse	Kidney	rep_2	3.9e-169
Hhatl	GOBP_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Kidney	rep_2	5.3e-140
Hhatl	GOBP_Regulation_Of_Protein_Lipidation	Mouse	Kidney	rep_2	2.7e-80
Hhatl	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	rep_2	2.2e-44
Hhatl	GOBP_N_Terminal_Protein_Amino_Acid_Modification	Mouse	Liver	CN16-E1	1.1e-10
Hhatl	GOBP_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Liver	CN73-C1	2.9e-09
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Liver	rep_15	1.2e-09
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Brain	rep_1	1.4e-08
Hhatl	GOBP_Negative_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Intestine	rep_3	3.0e-07
Hhatl	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Lymph	MS-1	6.0e-07
Hhatl	GOBP_Lipoprotein_Metabolic_Process	Mouse	Lymph	MS-1	3.6e-09
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-11
Hhatl	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Mouse	Lymph	MS-1	1.4e-09
Hhatl	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Hhatl	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Lymph	MS-1	1.9e-12
Hhatl	GOBP_Negative_Regulation_Of_Lipoprotein_Metabolic_Process	Mouse	Lymph	MS-2	4.6e-07
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Hhatl	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.0e-07
Hhatl	GOBP_N_Terminal_Protein_Amino_Acid_Modification	Mouse	Brain	HP_ad_rep7	2.7e-11
Hhatl	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Hhatl	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.1e-09
Hhatl	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Mouse	Brain	HP_ad_rep7	1.5e-10
Hhatl	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Hhatl	GOBP_Protein_Acylation	Mouse	Brain	HP_ad_rep7	2.6e-07
Hhatl	GOBP_Protein_Palmitoylation	Mouse	Brain	HP_ad_rep7	1.2e-11
Hhatl	GOBP_Regulation_Of_Protein_Lipidation	Mouse	Brain	HP_ad_rep7	1.6e-10
Hhatl	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Brain	HP_ad_rep7	1.1e-07
Hhatl	GOBP_Lipoprotein_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.6e-14
Hhatl	GOBP_N_Terminal_Protein_Lipidation	Mouse	Brain	HP_polb_rep9	3.4e-24

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Hhatl function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Hhatl function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Hhatl envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Hhatl

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Hhatl

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source