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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pcf11 (spascer ID:74737)

Gene summary for Pcf11

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pcf11
	Gene ID	74737
	Gene name	PCF11 cleavage and polyadenylation factor subunit
	Synonyms	2500001H09Rik\|5730417B17Rik\|C77803
	Cytomap	7\|7 E1
	Type of gene	protein-coding
	Description	pre-mRNA cleavage complex 2 protein Pcf11cleavage and polyadenylation factor subunit homolog
	Modification date	20220424
	UniProtAcc

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pcf11	GO:0000993	RNA polymerase II complex binding	21873635	Function
Pcf11	GO:0003729	mRNA binding	21873635	Function
Pcf11	GO:0005737	cytoplasm	21873635	Component
Pcf11	GO:0005849	mRNA cleavage factor complex	21873635	Component
Pcf11	GO:0006369	termination of RNA polymerase II transcription	21873635	Process
Pcf11	GO:0006378	mRNA polyadenylation	21873635	Process

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Spatial pattern events for Pcf11

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pcf11	Mouse	Kidney	IRI	34003797	1.91e-09
Pcf11	Mouse	Kidney	rep_3	34853151	1.42e-06
Pcf11	Mouse	Brain	rep_1	33469025	4.52e-15
Pcf11	Mouse	Intestine	rep_4	35149721	1.62e-07
Pcf11	Mouse	Lymph	A1	0	7.18e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E
Kidney_rep_3_H&E
Brain_rep_1_H&E

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Spatial pattern pathway has Pcf11 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Pcf11	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Mouse	Spinal cord	CN94_E1	5.8e-06
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Spinal cord	L7bCN01_D2	4.9e-06
Pcf11	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Spinal cord	L7bCN02_E1	8.2e-06
Pcf11	GOBP_Dna_Templated_Transcription_Termination	Mouse	Spinal cord	L7CN45_C1	1.4e-07
Pcf11	GOBP_Mrna_3_End_Processing	Mouse	Spinal cord	L7CN45_C1	9.8e-06
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Spinal cord	L7CN45_C1	9.6e-06
Pcf11	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Pcf11	GOBP_Rna_Splicing	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Pcf11	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Spinal cord	L7CN45_C1	1.8e-09
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Spinal cord	L7CN45_C1	4.9e-06
Pcf11	GOBP_Mrna_Cleavage	Mouse	Spinal cord	L7CN47_D1	5.8e-06
Pcf11	GOBP_Mrna_3_End_Processing	Mouse	Brain	rep_27	3.0e-05
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Brain	rep_27	4.5e-09
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Brain	rep_27	8.1e-08
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Brain	rep_41	2.5e-06
Pcf11	GOBP_Dna_Templated_Transcription_Termination	Mouse	Brain	rep_1	5.4e-10
Pcf11	GOBP_Mrna_3_End_Processing	Mouse	Brain	rep_1	8.1e-07
Pcf11	GOBP_Mrna_Cleavage	Mouse	Brain	rep_1	1.5e-07
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Brain	rep_1	4.2e-07
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Brain	rep_1	2.0e-55
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Pcf11	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Pcf11	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Mouse	Brain	rep_3	1.9e-149
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Brain	rep_3	2.2e-166
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Brain	rep_3	2.5e-155
Pcf11	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Pcf11	GOBP_Rna_Splicing	Mouse	Brain	rep_3	2.2e-224
Pcf11	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	rep_3	1.8e-234
Pcf11	GOBP_Dna_Templated_Transcription_Termination	Mouse	Embryo	rep_14	1.5e-52
Pcf11	GOBP_Mrna_Cleavage	Mouse	Embryo	rep_14	4.6e-51
Pcf11	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Mouse	Embryo	rep_14	3.6e-15
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Embryo	rep_14	4.1e-27
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Embryo	rep_14	1.1e-17
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Embryo	rep_14	7.0e-24
Pcf11	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Embryo	rep_14	2.3e-60
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Embryo	rep_2	2.8e-16
Pcf11	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Pcf11	GOBP_Dna_Templated_Transcription_Termination	Mouse	Kidney	rep_2	4.1e-111
Pcf11	GOBP_Mrna_3_End_Processing	Mouse	Kidney	rep_2	2.0e-28
Pcf11	GOBP_Mrna_Cleavage	Mouse	Kidney	rep_2	1.0e-58
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Pcf11	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Pcf11	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Mouse	Kidney	rep_2	3.2e-102
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Kidney	rep_2	2.8e-70
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Kidney	rep_2	1.8e-86
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Kidney	rep_2	5.4e-41
Pcf11	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Pcf11	GOBP_Rna_Splicing	Mouse	Kidney	rep_2	1.1e-33
Pcf11	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Kidney	rep_2	8.8e-36
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Kidney	rep_2	2.2e-53
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Pcf11	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Pcf11	GOBP_Rna_Splicing	Mouse	Liver	CN16-D2	2.4e-07
Pcf11	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Liver	CN16-D2	2.0e-09
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Liver	CN16-E1	2.6e-07
Pcf11	GOBP_Dna_Templated_Transcription_Termination	Mouse	Liver	rep_15	3.9e-07
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Liver	rep_15	9.1e-15
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Brain	rep_1	3.7e-15
Pcf11	GOBP_Mrna_3_End_Processing	Mouse	Lymph	MS-1	2.6e-07
Pcf11	GOBP_Mrna_Cleavage	Mouse	Lymph	MS-1	2.1e-08
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Pcf11	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Mouse	Lymph	MS-1	1.4e-09
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Lymph	MS-1	1.5e-11
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Lymph	MS-1	9.3e-10
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Lymph	MS-1	1.0e-12
Pcf11	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Pcf11	GOBP_Mrna_Cleavage	Mouse	Brain	rep_7	4.4e-10
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Brain	rep_7	3.3e-11
Pcf11	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Mouse	Brain	HP_ad_rep3	5.4e-18
Pcf11	GOBP_Dna_Templated_Transcription_Termination	Mouse	Brain	HP_ad_rep7	3.0e-07
Pcf11	GOBP_Mrna_3_End_Processing	Mouse	Brain	HP_ad_rep7	3.7e-18
Pcf11	GOBP_Mrna_Cleavage	Mouse	Brain	HP_ad_rep7	2.5e-20
Pcf11	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Pcf11	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Pcf11	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Mouse	Brain	HP_ad_rep7	3.0e-09
Pcf11	GOBP_Rna_3_End_Processing	Mouse	Brain	HP_ad_rep7	1.1e-14
Pcf11	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Mouse	Brain	HP_ad_rep7	4.6e-12
Pcf11	GOBP_Rna_Polyadenylation	Mouse	Brain	HP_ad_rep7	1.6e-11
Pcf11	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Pcf11	GOBP_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.3e-10
Pcf11	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	HP_ad_rep7	2.3e-11

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Pcf11 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pcf11 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pcf11 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pcf11

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pcf11

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source