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Spatial pattern gene: Abcb8 (spascer ID:74610) |
Gene summary for Abcb8 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Abcb8 | Gene ID | 74610 |
| Gene name | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| Synonyms | 4833412N02Rik|AA409895|MITOSUR |
| Cytomap | 5|5 A3 |
| Type of gene | protein-coding |
| Description | mitochondrial potassium channel ATP-binding subunitATP-binding cassette sub-family B member 8, mitochondrialmitochondrial sulfonylurea-receptor |
| Modification date | 20220424 |
| UniProtAcc | Q9CXJ4 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Abcb8 | GO:0016021 | integral component of membrane | 21873635 | Component |
| Abcb8 | GO:0042626 | ATPase-coupled transmembrane transporter activity | 21873635 | Function |
| Abcb8 | GO:0055085 | transmembrane transport | 21873635 | Process |
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Spatial pattern events for Abcb8 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Abcb8 | Mouse | Kidney | IRI | 34003797 | 3.92e-15 |
| Abcb8 | Mouse | Lung | rep_4 | 35290801 | 8.58e-06 |
| Abcb8 | Mouse | Brain | rep_1 | 35210624 | 2.37e-14 |
| Abcb8 | Mouse | Brain | rep_2 | 35210624 | 6.98e-13 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_IRI_H&E  |  |
Lung_rep_4_H&E  |  |
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Spatial pattern pathway has Abcb8 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Abcb8 | GOBP_Cation_Transport | Mouse | Spinal cord | CN94_E1 | 5.8e-06 |
| Abcb8 | GOBP_Cation_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 1.3e-08 |
| Abcb8 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 6.6e-07 |
| Abcb8 | GOBP_Potassium_Ion_Transport | Mouse | Spinal cord | L7CN45_C1 | 9.1e-09 |
| Abcb8 | GOBP_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 3.5e-08 |
| Abcb8 | GOBP_Cation_Transmembrane_Transport | Mouse | Brain | rep_1 | 4.4e-30 |
| Abcb8 | GOBP_Cation_Transport | Mouse | Brain | rep_1 | 1.5e-22 |
| Abcb8 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Brain | rep_1 | 8.6e-24 |
| Abcb8 | GOBP_Potassium_Ion_Transport | Mouse | Brain | rep_1 | 3.5e-56 |
| Abcb8 | GOBP_Transmembrane_Transport | Mouse | Brain | rep_1 | 3.1e-23 |
| Abcb8 | GOBP_Transmembrane_Transport | Mouse | Kidney | Nep | 4.2e-26 |
| Abcb8 | GOBP_Cation_Transmembrane_Transport | Mouse | Kidney | rep_2 | 7.3e-17 |
| Abcb8 | GOBP_Cation_Transport | Mouse | Kidney | rep_2 | 5.9e-23 |
| Abcb8 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Kidney | rep_2 | 2.4e-15 |
| Abcb8 | GOBP_Potassium_Ion_Transport | Mouse | Kidney | rep_2 | 2.8e-73 |
| Abcb8 | GOBP_Transmembrane_Transport | Mouse | Kidney | rep_2 | 2.7e-23 |
| Abcb8 | GOBP_Cation_Transmembrane_Transport | Mouse | Liver | rep_15 | 8.9e-14 |
| Abcb8 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Liver | rep_15 | 2.4e-07 |
| Abcb8 | GOBP_Cation_Transport | Mouse | Liver | rep_16 | 1.2e-18 |
| Abcb8 | GOBP_Potassium_Ion_Transport | Mouse | Liver | rep_16 | 3.8e-11 |
| Abcb8 | GOBP_Transmembrane_Transport | Mouse | Liver | rep_16 | 1.4e-13 |
| Abcb8 | GOBP_Potassium_Ion_Transport | Mouse | Lymph | MS-1 | 3.6e-10 |
| Abcb8 | GOBP_Cation_Transport | Mouse | Brain | HP_ad_rep7 | 7.5e-07 |
| Abcb8 | GOBP_Transmembrane_Transport | Mouse | Brain | HP_ad_rep7 | 3.4e-07 |
| Abcb8 | GOBP_Cation_Transmembrane_Transport | Mouse | Brain | HP_polb_rep9 | 1.4e-07 |
| Abcb8 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Brain | HP_polb_rep9 | 1.1e-07 |
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Abcb8 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Abcb8 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Abcb8 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Abcb8 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Abcb8 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
