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Spatial pattern gene: Hbp1 (spascer ID:73389) |
Gene summary for Hbp1 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Hbp1 | Gene ID | 73389 |
| Gene name | high mobility group box transcription factor 1 |
| Synonyms | 1700058O05Rik|BE629963|C330012F01Rik|C86454 |
| Cytomap | 12|12 A3 |
| Type of gene | protein-coding |
| Description | HMG box-containing protein 1HMG box transcription factor 1 |
| Modification date | 20220424 |
| UniProtAcc | Q8R316 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Hbp1 | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 21873635 | Function |
| Hbp1 | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 21873635 | Function |
| Hbp1 | GO:0005634 | nucleus | 21873635 | Component |
| Hbp1 | GO:0006357 | regulation of transcription by RNA polymerase II | 21873635 | Process |
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Spatial pattern events for Hbp1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Hbp1 | Mouse | Brain | S2 | 34413515 | 4.19e-06 |
| Hbp1 | Mouse | Brain | S3 | 34413515 | 7.08e-07 |
| Hbp1 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Hbp1 | Mouse | Brain | S6 | 34413515 | 6.41e-14 |
| Hbp1 | Mouse | Brain | S7 | 34413515 | 2.47e-10 |
| Hbp1 | Mouse | Brain | rep_2 | 35141374 | 4.30e-11 |
| Hbp1 | Mouse | Brain | rep_5 | 35141374 | 3.41e-06 |
| Hbp1 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Hbp1 | Mouse | Kidney | IRI | 34003797 | 4.99e-14 |
| Hbp1 | Mouse | Kidney | rep_1 | 34853151 | 2.24e-07 |
| Hbp1 | Mouse | Kidney | rep_3 | 34853151 | 5.76e-07 |
| Hbp1 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Hbp1 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Hbp1 | Mouse | Brain | rep_2 | 35027729 | 3.32e-09 |
| Hbp1 | Mouse | Brain | rep_3 | 35027729 | 4.57e-15 |
| Hbp1 | Mouse | Brain | rep_4 | 35027729 | 2.87e-07 |
| Hbp1 | Mouse | Brain | rep_5 | 35027729 | 5.00e-15 |
| Hbp1 | Mouse | Brain | rep_1 | 35210624 | 4.38e-09 |
| Hbp1 | Mouse | Brain | rep_2 | 35210624 | 2.50e-09 |
| Hbp1 | Mouse | Brain | rep_3 | 35210624 | 1.19e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_2_H&E  |  |
Brain_rep_5_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Hbp1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Hbp1 | GOBP_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 1.1e-06 |
| Hbp1 | GOBP_Cell_Cycle_Process | Mouse | Spinal cord | CN94_E1 | 3.8e-06 |
| Hbp1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 3.2e-06 |
| Hbp1 | GOBP_Cell_Cell_Signaling | Mouse | Spinal cord | L7CN45_C1 | 3.5e-08 |
| Hbp1 | GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling | Mouse | Spinal cord | L7CN45_C1 | 5.6e-07 |
| Hbp1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Spinal cord | L7CN45_C1 | 3.0e-07 |
| Hbp1 | GOBP_Cell_Cell_Signaling_By_Wnt | Mouse | Spinal cord | L8CN17_E1 | 3.7e-07 |
| Hbp1 | GOBP_Cell_Cycle | Mouse | Brain | rep_27 | 8.4e-07 |
| Hbp1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_27 | 1.7e-08 |
| Hbp1 | GOBP_Cell_Cell_Signaling | Mouse | Brain | rep_1 | 5.1e-48 |
| Hbp1 | GOBP_Cell_Cycle | Mouse | Brain | rep_1 | 7.0e-10 |
| Hbp1 | GOBP_Cell_Cycle_Process | Mouse | Brain | rep_1 | 6.7e-14 |
| Hbp1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_1 | 3.9e-14 |
| Hbp1 | GOBP_Cell_Cell_Signaling_By_Wnt | Mouse | Brain | rep_3 | 2.0e-124 |
| Hbp1 | GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling | Mouse | Brain | rep_3 | 3.3e-46 |
| Hbp1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_3 | 1.9e-186 |
| Hbp1 | GOBP_Cell_Cell_Signaling_By_Wnt | Mouse | Embryo | rep_6 | 1.7e-33 |
| Hbp1 | GOBP_Cell_Cell_Signaling | Mouse | Kidney | rep_2 | 6.2e-72 |
| Hbp1 | GOBP_Cell_Cell_Signaling_By_Wnt | Mouse | Kidney | rep_2 | 2.1e-78 |
| Hbp1 | GOBP_Cell_Cycle | Mouse | Kidney | rep_2 | 1.0e-24 |
| Hbp1 | GOBP_Cell_Cycle_Process | Mouse | Kidney | rep_2 | 3.0e-21 |
| Hbp1 | GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling | Mouse | Kidney | rep_2 | 6.7e-89 |
| Hbp1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Kidney | rep_2 | 2.8e-71 |
| Hbp1 | GOBP_Cell_Cell_Signaling | Mouse | Lymph | MS-1 | 9.7e-11 |
| Hbp1 | GOBP_Cell_Cell_Signaling_By_Wnt | Mouse | Lymph | MS-1 | 7.3e-10 |
| Hbp1 | GOBP_Cell_Cycle | Mouse | Lymph | MS-1 | 1.3e-07 |
| Hbp1 | GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling | Mouse | Lymph | MS-1 | 1.6e-11 |
| Hbp1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Lymph | MS-1 | 9.2e-07 |
| Hbp1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Lymph | MS-1 | 6.4e-09 |
| Hbp1 | GOBP_Cell_Cell_Signaling | Mouse | Brain | HP_ad_rep7 | 1.6e-08 |
| Hbp1 | GOBP_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 6.6e-08 |
| Hbp1 | GOBP_Cell_Cycle_Process | Mouse | Brain | HP_ad_rep7 | 1.7e-09 |
| Hbp1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 9.2e-08 |
| Hbp1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 1.6e-08 |
| Hbp1 | GOBP_Cell_Cell_Signaling_By_Wnt | Mouse | Brain | HP_polb_rep9 | 1.7e-14 |
| Hbp1 | GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling | Mouse | Brain | HP_polb_rep9 | 1.2e-14 |
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Hbp1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Hbp1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Hbp1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| HBP1 | Uterus | mid | Glandular_secretory | RBM4B,TRIM33,FOXO3, etc. | 0.599 |
| HBP1 | Uterus | mid | Glandular | RBM4B,TRIM33,FOXO3, etc. | 0.265 |
| Motif information. |
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Related Drugs for Hbp1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Hbp1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
