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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Rhobtb3 (spascer ID:73296)

Gene summary for Rhobtb3

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Rhobtb3
	Gene ID	73296
	Gene name	Rho-related BTB domain containing 3
	Synonyms	1700040C17Rik\|2610033K01Rik\|4930503C18Rik\|AI317148\|AW208826\|mKIAA0878
	Cytomap	13\|13 C1
	Type of gene	protein-coding
	Description	rho-related BTB domain-containing protein 3
	Modification date	20220424
	UniProtAcc	Q9CTN4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Rhobtb3	GO:0003924	GTPase activity	21873635	Function
Rhobtb3	GO:0005525	GTP binding	21873635	Function
Rhobtb3	GO:0005856	cytoskeleton	21873635	Component
Rhobtb3	GO:0005886	plasma membrane	21873635	Component
Rhobtb3	GO:0005938	cell cortex	21873635	Component
Rhobtb3	GO:0007015	actin filament organization	21873635	Process
Rhobtb3	GO:0007163	establishment or maintenance of cell polarity	21873635	Process
Rhobtb3	GO:0008360	regulation of cell shape	21873635	Process
Rhobtb3	GO:0016477	cell migration	21873635	Process
Rhobtb3	GO:0019901	protein kinase binding	21873635	Function
Rhobtb3	GO:0030865	cortical cytoskeleton organization	21873635	Process
Rhobtb3	GO:0031410	cytoplasmic vesicle	21873635	Component
Rhobtb3	GO:0032956	regulation of actin cytoskeleton organization	21873635	Process
Rhobtb3	GO:0042995	cell projection	21873635	Component

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Spatial pattern events for Rhobtb3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Rhobtb3	Mouse	Brain	S1	34413515	3.73e-15
Rhobtb3	Mouse	Brain	S2	34413515	1.56e-15
Rhobtb3	Mouse	Brain	S3	34413515	5.44e-07
Rhobtb3	Mouse	Brain	S4	34413515	1.37e-15
Rhobtb3	Mouse	Brain	S6	34413515	1.46e-15
Rhobtb3	Mouse	Brain	S7	34413515	1.55e-15
Rhobtb3	Mouse	Brain	13A	32637622	2.52e-06
Rhobtb3	Mouse	Brain	27A	32637622	2.07e-13
Rhobtb3	Mouse	Brain	27B	32637622	3.36e-09
Rhobtb3	Mouse	Brain	rep_3	35141374	7.87e-07
Rhobtb3	Mouse	Brain	rep_5	35141374	9.57e-07
Rhobtb3	Mouse	Embryo	rep_4	33188776	7.48e-08
Rhobtb3	Mouse	Brain	rep_1	35027729	1.66e-15
Rhobtb3	Mouse	Brain	rep_2	35027729	1.57e-15
Rhobtb3	Mouse	Brain	rep_3	35027729	1.32e-15
Rhobtb3	Mouse	Brain	rep_4	35027729	1.76e-15
Rhobtb3	Mouse	Brain	rep_5	35027729	1.46e-15
Rhobtb3	Mouse	Lymph	B1	0	8.99e-06
Rhobtb3	Mouse	Brain	rep_1	35210624	8.92e-08
Rhobtb3	Mouse	Brain	rep_3	35210624	5.73e-12
Rhobtb3	Mouse	Brain	rep_5	35210624	1.63e-08
Rhobtb3	Mouse	Brain	rep_7	35210624	6.18e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_3_H&E
Brain_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Rhobtb3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Rhobtb3	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Spinal cord	CN94_E1	3.2e-07
Rhobtb3	GOBP_Reproduction	Mouse	Spinal cord	CN94_E1	7.8e-08
Rhobtb3	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Rhobtb3	GOBP_Cytosolic_Transport	Mouse	Spinal cord	L7bCN02_E1	2.2e-06
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	6.0e-09
Rhobtb3	GOBP_Endosomal_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-08
Rhobtb3	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Spinal cord	L7CN45_C1	4.7e-06
Rhobtb3	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Rhobtb3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Rhobtb3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Rhobtb3	GOBP_Regulation_Of_Cell_Shape	Mouse	Spinal cord	L7CN45_C1	2.7e-06
Rhobtb3	GOBP_Retrograde_Transport_Endosome_To_Golgi	Mouse	Spinal cord	L7CN45_C1	8.8e-06
Rhobtb3	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Rhobtb3	GOBP_Male_Sex_Differentiation	Mouse	Spinal cord	L7CN47_C1	4.2e-06
Rhobtb3	GOBP_Cell_Migration	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Rhobtb3	GOBP_Locomotion	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Rhobtb3	GOBP_Actin_Filament_Organization	Mouse	Spinal cord	L8CN17_E1	2.1e-07
Rhobtb3	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Spinal cord	L8CN17_E1	1.5e-07
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	rep_27	1.4e-06
Rhobtb3	GOBP_Cytosolic_Transport	Mouse	Brain	rep_27	5.1e-05
Rhobtb3	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Rhobtb3	GOBP_Actin_Filament_Organization	Mouse	Brain	rep_1	4.6e-31
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Brain	rep_1	7.6e-08
Rhobtb3	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Rhobtb3	GOBP_Cytosolic_Transport	Mouse	Brain	rep_1	3.9e-26
Rhobtb3	GOBP_Endosomal_Transport	Mouse	Brain	rep_1	8.9e-24
Rhobtb3	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.2e-33
Rhobtb3	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-40
Rhobtb3	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	7.9e-20
Rhobtb3	GOBP_Retrograde_Transport_Endosome_To_Golgi	Mouse	Brain	rep_1	1.2e-36
Rhobtb3	GOBP_Cell_Migration	Mouse	Brain	rep_3	4.9e-108
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-64
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Brain	rep_3	2.5e-171
Rhobtb3	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Brain	rep_3	2.9e-159
Rhobtb3	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Brain	rep_3	6.8e-85
Rhobtb3	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
Rhobtb3	GOBP_Locomotion	Mouse	Brain	rep_3	5.4e-74
Rhobtb3	GOBP_Male_Sex_Differentiation	Mouse	Brain	rep_3	4.2e-151
Rhobtb3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	rep_3	3.2e-44
Rhobtb3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Brain	rep_3	5.0e-45
Rhobtb3	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	rep_3	2.1e-19
Rhobtb3	GOBP_Reproduction	Mouse	Brain	rep_3	3.4e-125
Rhobtb3	GOBP_Reproductive_System_Development	Mouse	Brain	rep_3	1.3e-174
Rhobtb3	GOBP_Sex_Differentiation	Mouse	Brain	rep_3	6.9e-174
Rhobtb3	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	6.7e-78
Rhobtb3	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Embryo	rep_6	4.1e-07
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Embryo	rep_14	1.3e-18
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Embryo	rep_14	1.2e-09
Rhobtb3	GOBP_Male_Sex_Differentiation	Mouse	Embryo	rep_14	5.8e-13
Rhobtb3	GOBP_Regulation_Of_Cell_Shape	Mouse	Embryo	rep_14	5.1e-07
Rhobtb3	GOBP_Reproductive_System_Development	Mouse	Embryo	rep_14	1.6e-09
Rhobtb3	GOBP_Retrograde_Transport_Endosome_To_Golgi	Mouse	Embryo	rep_14	4.1e-17
Rhobtb3	GOBP_Sex_Differentiation	Mouse	Embryo	rep_14	1.7e-14
Rhobtb3	GOBP_Cell_Migration	Mouse	Embryo	rep_1	7.4e-36
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Embryo	rep_1	1.2e-66
Rhobtb3	GOBP_Locomotion	Mouse	Embryo	rep_1	1.7e-10
Rhobtb3	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Embryo	rep_1	2.6e-63
Rhobtb3	GOBP_Sex_Differentiation	Mouse	Embryo	rep_1	7.0e-66
Rhobtb3	GOBP_Regulation_Of_Organelle_Organization	Mouse	Embryo	rep_3	1.3e-27
Rhobtb3	GOBP_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_3	0.0e+00
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Embryo	rep_5	2.2e-13
Rhobtb3	GOBP_Cell_Migration	Mouse	Kidney	Nep	5.3e-07
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Kidney	Nep	1.1e-16
Rhobtb3	GOBP_Locomotion	Mouse	Kidney	Nep	5.3e-07
Rhobtb3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	Nep	1.3e-32
Rhobtb3	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Rhobtb3	GOBP_Actin_Filament_Organization	Mouse	Kidney	rep_2	4.0e-81
Rhobtb3	GOBP_Cell_Migration	Mouse	Kidney	rep_2	4.7e-40
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.7e-84
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-78
Rhobtb3	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Rhobtb3	GOBP_Cytosolic_Transport	Mouse	Kidney	rep_2	1.9e-78
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Kidney	rep_2	3.2e-15
Rhobtb3	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Kidney	rep_2	3.6e-46
Rhobtb3	GOBP_Endosomal_Transport	Mouse	Kidney	rep_2	1.5e-111
Rhobtb3	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
Rhobtb3	GOBP_Locomotion	Mouse	Kidney	rep_2	2.1e-43
Rhobtb3	GOBP_Male_Sex_Differentiation	Mouse	Kidney	rep_2	5.6e-14
Rhobtb3	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.1e-74
Rhobtb3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	rep_2	1.3e-133
Rhobtb3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.9e-85
Rhobtb3	GOBP_Regulation_Of_Cell_Shape	Mouse	Kidney	rep_2	3.0e-66
Rhobtb3	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.8e-22
Rhobtb3	GOBP_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	6.7e-77
Rhobtb3	GOBP_Reproduction	Mouse	Kidney	rep_2	9.0e-46
Rhobtb3	GOBP_Reproductive_System_Development	Mouse	Kidney	rep_2	6.4e-28
Rhobtb3	GOBP_Retrograde_Transport_Endosome_To_Golgi	Mouse	Kidney	rep_2	3.7e-84
Rhobtb3	GOBP_Sex_Differentiation	Mouse	Kidney	rep_2	4.6e-19
Rhobtb3	GOBP_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.5e-65
Rhobtb3	GOBP_Cytosolic_Transport	Mouse	Liver	CN16-D2	3.1e-07
Rhobtb3	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Liver	CN16-D2	3.2e-07
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Liver	CN16-E1	4.8e-07
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Liver	rep_15	9.0e-09
Rhobtb3	GOBP_Cell_Migration	Mouse	Liver	rep_26	1.6e-10
Rhobtb3	GOBP_Locomotion	Mouse	Liver	rep_26	1.6e-10
Rhobtb3	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Rhobtb3	GOBP_Actin_Filament_Organization	Mouse	Lymph	MS-1	4.2e-11
Rhobtb3	GOBP_Cell_Migration	Mouse	Lymph	MS-1	5.7e-13
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Lymph	MS-1	3.9e-13
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.5e-14
Rhobtb3	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Lymph	MS-1	4.7e-12
Rhobtb3	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Lymph	MS-1	2.2e-10
Rhobtb3	GOBP_Endosomal_Transport	Mouse	Lymph	MS-1	9.8e-11
Rhobtb3	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Rhobtb3	GOBP_Locomotion	Mouse	Lymph	MS-1	1.2e-12
Rhobtb3	GOBP_Male_Sex_Differentiation	Mouse	Lymph	MS-1	5.2e-09
Rhobtb3	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.7e-09
Rhobtb3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Lymph	MS-1	2.4e-16
Rhobtb3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Lymph	MS-1	2.2e-13
Rhobtb3	GOBP_Regulation_Of_Cell_Shape	Mouse	Lymph	MS-1	5.2e-14
Rhobtb3	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Lymph	MS-1	8.4e-09
Rhobtb3	GOBP_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	1.4e-10
Rhobtb3	GOBP_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Rhobtb3	GOBP_Reproductive_System_Development	Mouse	Lymph	MS-1	2.4e-11
Rhobtb3	GOBP_Retrograde_Transport_Endosome_To_Golgi	Mouse	Lymph	MS-1	1.1e-09
Rhobtb3	GOBP_Sex_Differentiation	Mouse	Lymph	MS-1	4.7e-12
Rhobtb3	GOBP_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	1.5e-12
Rhobtb3	GOBP_Reproduction	Mouse	Lung	rep_1	9.6e-12
Rhobtb3	GOBP_Endosomal_Transport	Mouse	Brain	rep_4	2.6e-13
Rhobtb3	GOBP_Cell_Migration	Mouse	Brain	HP_ad_rep7	2.2e-07
Rhobtb3	GOBP_Cell_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.4e-10
Rhobtb3	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Rhobtb3	GOBP_Cytosolic_Transport	Mouse	Brain	HP_ad_rep7	7.7e-08
Rhobtb3	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Brain	HP_ad_rep7	2.5e-08
Rhobtb3	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Brain	HP_ad_rep7	4.1e-10
Rhobtb3	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
Rhobtb3	GOBP_Locomotion	Mouse	Brain	HP_ad_rep7	3.8e-07
Rhobtb3	GOBP_Male_Sex_Differentiation	Mouse	Brain	HP_ad_rep7	5.6e-07
Rhobtb3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	HP_ad_rep7	3.3e-08
Rhobtb3	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	8.1e-07
Rhobtb3	GOBP_Reproduction	Mouse	Brain	HP_ad_rep7	7.9e-09
Rhobtb3	GOBP_Retrograde_Transport_Endosome_To_Golgi	Mouse	Brain	HP_ad_rep7	2.2e-10
Rhobtb3	GOBP_Sex_Differentiation	Mouse	Brain	HP_ad_rep7	6.4e-09
Rhobtb3	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	HP_ad_rep7	5.2e-07
Rhobtb3	GOBP_Development_Of_Primary_Sexual_Characteristics	Mouse	Brain	HP_adpolb_rep1	7.3e-09
Rhobtb3	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07
Rhobtb3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.2e-10
Rhobtb3	GOBP_Endosomal_Transport	Mouse	Brain	HP_polb_rep9	2.8e-14
Rhobtb3	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	HP_polb_rep9	2.9e-08
Rhobtb3	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.1e-07
Rhobtb3	GOBP_Reproductive_System_Development	Mouse	Brain	HP_polb_rep9	8.3e-10

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Rhobtb3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Rhobtb3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Rhobtb3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Rhobtb3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Rhobtb3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source