|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Ddit4l (spascer ID:73284) |
Gene summary for Ddit4l |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Ddit4l | Gene ID | 73284 |
| Gene name | DNA-damage-inducible transcript 4-like |
| Synonyms | 1700037B15Rik|1700108M02Rik|REDD2|RTP801L|Smhs1 |
| Cytomap | 3|3 G3 |
| Type of gene | protein-coding |
| Description | DNA damage-inducible transcript 4-like proteinHIF-1 responsive protein RTP801-likeskeletal muscle hindlimb suspension 1soleus muscle atrophied after hindlimb suspension protein 1 |
| Modification date | 20220424 |
| UniProtAcc | Q8VHZ5 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
Top |
Spatial pattern events for Ddit4l |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Ddit4l | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Ddit4l | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Ddit4l | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Ddit4l | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Ddit4l | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Ddit4l | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Ddit4l | Mouse | Brain | 12B | 32637622 | 1.36e-07 |
| Ddit4l | Mouse | Brain | 13B | 32637622 | 2.33e-07 |
| Ddit4l | Mouse | Brain | 14A | 32637622 | 2.50e-10 |
| Ddit4l | Mouse | Brain | 14B | 32637622 | 2.44e-12 |
| Ddit4l | Mouse | Brain | 16A | 32637622 | 2.39e-06 |
| Ddit4l | Mouse | Brain | 16B | 32637622 | 7.34e-06 |
| Ddit4l | Mouse | Brain | 17A | 32637622 | 6.40e-06 |
| Ddit4l | Mouse | Brain | 17B | 32637622 | 9.98e-10 |
| Ddit4l | Mouse | Brain | 18B | 32637622 | 1.97e-09 |
| Ddit4l | Mouse | Brain | 21A | 32637622 | 3.33e-08 |
| Ddit4l | Mouse | Brain | 22A | 32637622 | 8.69e-08 |
| Ddit4l | Mouse | Brain | 22B | 32637622 | 2.39e-12 |
| Ddit4l | Mouse | Brain | 24B | 32637622 | 1.53e-09 |
| Ddit4l | Mouse | Brain | 29A | 32637622 | 5.94e-06 |
| Ddit4l | Mouse | Brain | rep_1 | 35141374 | 2.02e-15 |
| Ddit4l | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Ddit4l | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Ddit4l | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Ddit4l | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Ddit4l | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Ddit4l | Mouse | Embryo | rep_1 | 34489600 | 3.74e-16 |
| Ddit4l | Mouse | Embryo | rep_2 | 34489600 | 4.14e-16 |
| Ddit4l | Mouse | Embryo | rep_3 | 34489600 | 4.04e-16 |
| Ddit4l | Mouse | Embryo | rep_4 | 34489600 | 3.67e-16 |
| Ddit4l | Mouse | Embryo | rep_5 | 34489600 | 4.08e-16 |
| Ddit4l | Mouse | Embryo | rep_6 | 34489600 | 3.64e-16 |
| Ddit4l | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Ddit4l | Mouse | Kidney | IRI | 34003797 | 4.99e-14 |
| Ddit4l | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Ddit4l | Mouse | Kidney | rep_3 | 34853151 | 4.93e-15 |
| Ddit4l | Mouse | Liver | rep_20 | 35021063 | 9.59e-11 |
| Ddit4l | Mouse | Liver | rep_21 | 35021063 | 1.00e-13 |
| Ddit4l | Mouse | Liver | rep_22 | 35021063 | 3.24e-13 |
| Ddit4l | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Ddit4l | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Ddit4l | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Ddit4l | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Ddit4l | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Ddit4l | Mouse | Brain | B02_D1 | 32702314 | 1.23e-07 |
| Ddit4l | Mouse | Brain | B03_C2 | 32702314 | 2.96e-06 |
| Ddit4l | Mouse | Brain | B03_D2 | 32702314 | 4.44e-07 |
| Ddit4l | Mouse | Brain | N03_C2 | 32702314 | 2.28e-08 |
| Ddit4l | Mouse | Brain | N03_D2 | 32702314 | 1.38e-14 |
| Ddit4l | Mouse | Testicle | rep_5 | 34731600 | 4.11e-14 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_3_H&E  |  |
Liver_rep_20_H&E  | |
Liver_rep_21_H&E  | |
Liver_rep_22_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B02_D1_H&E  |  |
Brain_B03_C2_H&E  |  |
Brain_B03_D2_H&E  |  |
Brain_N03_C2_H&E  |  |
Brain_N03_D2_H&E  |  |
Top |
Spatial pattern pathway has Ddit4l envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Ddit4l | GOBP_Negative_Regulation_Of_Signaling | Mouse | Spinal cord | L8CN17_E1 | 8.3e-06 |
| Ddit4l | GOBP_Negative_Regulation_Of_Response_To_Stimulus | Mouse | Brain | rep_3 | 1.3e-138 |
| Ddit4l | GOBP_Negative_Regulation_Of_Signaling | Mouse | Brain | rep_3 | 7.8e-106 |
| Ddit4l | GOBP_Negative_Regulation_Of_Response_To_Stimulus | Mouse | Embryo | rep_1 | 1.1e-25 |
| Ddit4l | GOBP_Negative_Regulation_Of_Signaling | Mouse | Embryo | rep_1 | 5.6e-10 |
| Ddit4l | GOBP_Negative_Regulation_Of_Response_To_Stimulus | Mouse | Kidney | rep_2 | 1.7e-39 |
| Ddit4l | GOBP_Negative_Regulation_Of_Signaling | Mouse | Kidney | rep_2 | 4.0e-40 |
| Ddit4l | GOBP_Negative_Regulation_Of_Response_To_Stimulus | Mouse | Lymph | MS-1 | 1.5e-11 |
| Ddit4l | GOBP_Negative_Regulation_Of_Signaling | Mouse | Lymph | MS-1 | 1.0e-14 |
| Ddit4l | GOBP_Negative_Regulation_Of_Response_To_Stimulus | Mouse | Brain | HP_polb_rep9 | 3.1e-09 |
| Ddit4l | GOBP_Negative_Regulation_Of_Signaling | Mouse | Brain | HP_polb_rep9 | 1.4e-11 |
Top |
Ddit4l function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Ddit4l function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Ddit4l envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Ddit4l |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Ddit4l |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
