SPASCER Logo

Home

Download & Upload

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Ppp2r2b (spascer ID:72930)

Gene summary for Ppp2r2b

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Ppp2r2b

Gene ID

72930

Gene nameprotein phosphatase 2, regulatory subunit B, beta
Synonyms2900026H06Rik|6330404L05Rik|E130009M08Rik|PP2A-PR55B|PR55-BETA|SCA12
Cytomap18|18 B3
Type of geneprotein-coding
Descriptionserine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Modification date20220428
UniProtAcc

Q6ZWR4


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Ppp2r2b

GO:0000159

protein phosphatase type 2A complex

21873635

Component
Ppp2r2b

GO:0005829

cytosol

21873635

Component
Ppp2r2b

GO:0019888

protein phosphatase regulator activity

21873635

Function
Ppp2r2b

GO:0070262

peptidyl-serine dephosphorylation

21873635

Process

Top

Spatial pattern events for Ppp2r2b

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Ppp2r2bMouseBrainS1 344135152.07e-15
Ppp2r2bMouseBrainS2 344135151.56e-15
Ppp2r2bMouseBrainS3 344135151.64e-15
Ppp2r2bMouseBrainS4 344135151.37e-15
Ppp2r2bMouseBrainS6 344135151.46e-15
Ppp2r2bMouseBrainS7 344135151.55e-15
Ppp2r2bMouseBrain14B 326376221.10e-06
Ppp2r2bMouseBrain19A 326376229.56e-12
Ppp2r2bMouseBrain19B 326376224.09e-14
Ppp2r2bMouseBrain21B 326376222.75e-08
Ppp2r2bMouseBrain22A 326376225.97e-09
Ppp2r2bMouseBrain23A 326376222.77e-14
Ppp2r2bMouseBrain23B 326376221.23e-08
Ppp2r2bMouseBrain24A 326376221.66e-10
Ppp2r2bMouseBrain25A 326376223.78e-07
Ppp2r2bMouseBrain26B 326376228.97e-08
Ppp2r2bMouseBrain27A 326376221.23e-08
Ppp2r2bMouseBrain27B 326376221.80e-14
Ppp2r2bMouseBrain28A 326376221.23e-10
Ppp2r2bMouseBrain28B 326376223.87e-14
Ppp2r2bMouseBrainrep_1 351413742.02e-15
Ppp2r2bMouseBrainrep_2 351413741.69e-15
Ppp2r2bMouseBrainrep_3 351413741.64e-15
Ppp2r2bMouseBrainrep_4 351413741.57e-15
Ppp2r2bMouseBrainrep_5 351413741.47e-15
Ppp2r2bMouseBrainrep_6 351413741.73e-15
Ppp2r2bMouseEmbryo1D 342108872.07e-14
Ppp2r2bMouseEmbryo1F 342108872.89e-10
Ppp2r2bMouseEmbryo1G 342108871.66e-12
Ppp2r2bMouseEmbryo2G 342108877.59e-11
Ppp2r2bMouseEmbryo2H 342108879.16e-11
Ppp2r2bMouseEmbryo3D 342108872.78e-14
Ppp2r2bMouseEmbryo3F 342108875.82e-15
Ppp2r2bMouseEmbryo3G 342108878.80e-15
Ppp2r2bMouseEmbryo3H 342108871.63e-11
Ppp2r2bMouseEmbryo4A 342108872.38e-14
Ppp2r2bMouseEmbryo4C 342108871.65e-14
Ppp2r2bMouseEmbryo4D 342108877.75e-15
Ppp2r2bMouseEmbryo4E 342108874.53e-15
Ppp2r2bMouseBrainrep_1 334690251.30e-15
Ppp2r2bMouseBrainrep_1 350277291.66e-15
Ppp2r2bMouseBrainrep_2 350277291.57e-15
Ppp2r2bMouseBrainrep_3 350277291.32e-15
Ppp2r2bMouseBrainrep_4 350277291.76e-15
Ppp2r2bMouseBrainrep_5 350277291.46e-15
Ppp2r2bMouseBrainB02_D1 327023145.88e-12
Ppp2r2bMouseBrainB02_E1 327023142.23e-14
Ppp2r2bMouseBrainB03_D2 327023147.63e-13
Ppp2r2bMouseBrainrep_1 352106241.74e-15
Ppp2r2bMouseBrainrep_2 352106241.74e-15
Ppp2r2bMouseBrainrep_3 352106241.82e-15
Ppp2r2bMouseBrainrep_4 352106242.34e-15
Ppp2r2bMouseBrainrep_5 352106243.62e-15
Ppp2r2bMouseBrainrep_6 352106243.65e-15
Ppp2r2bMouseBrainrep_7 352106243.31e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
boxplot
boxplot
Brain_rep_2_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot
Brain_rep_4_H&E
boxplot
boxplot
Brain_rep_5_H&E
boxplot
boxplot
Brain_rep_6_H&E
boxplot
boxplot
Brain_rep_1_H&E
boxplot
Brain_rep_1_H&E
boxplot
boxplot
Brain_rep_2_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot
Brain_rep_4_H&E
boxplot
boxplot
Brain_rep_5_H&E
boxplot
boxplot
Brain_B02_D1_H&E
boxplot
boxplot
Brain_B02_E1_H&E
boxplot
boxplot
Brain_B03_D2_H&E
boxplot
boxplot


Top

Spatial pattern pathway has Ppp2r2b envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Ppp2r2bGOBP_Regulation_Of_Protein_DephosphorylationMouseSpinal cordCN93_D2 6.8e-06
Ppp2r2bGOBP_Protein_DephosphorylationMouseSpinal cordCN94_E1 5.2e-07
Ppp2r2bGOBP_Regulation_Of_Phosphatase_ActivityMouseSpinal cordCN94_E1 1.6e-06
Ppp2r2bGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseSpinal cordCN94_E1 5.2e-08
Ppp2r2bGOBP_DephosphorylationMouseSpinal cordL7CN45_C1 3.3e-07
Ppp2r2bGOBP_Peptidyl_Serine_DephosphorylationMouseSpinal cordL7CN45_C1 1.5e-06
Ppp2r2bGOBP_Regulation_Of_DephosphorylationMouseSpinal cordL7CN45_C1 1.4e-06
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseSpinal cordL7CN45_C1 2.3e-07
Ppp2r2bGOBP_Regulation_Of_Protein_Modification_ProcessMouseSpinal cordL7CN45_C1 4.2e-07
Ppp2r2bGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseSpinal cordL8CN11_C1 3.6e-13
Ppp2r2bGOBP_DephosphorylationMouseBrainrep_1 1.5e-40
Ppp2r2bGOBP_Protein_DephosphorylationMouseBrainrep_1 1.0e-26
Ppp2r2bGOBP_Regulation_Of_DephosphorylationMouseBrainrep_1 1.4e-28
Ppp2r2bGOBP_Regulation_Of_Phosphatase_ActivityMouseBrainrep_1 2.0e-14
Ppp2r2bGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseBrainrep_1 2.0e-07
Ppp2r2bGOBP_Regulation_Of_Protein_DephosphorylationMouseBrainrep_1 8.8e-22
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseBrainrep_31.4e-120
Ppp2r2bGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseBrainrep_3 3.0e-62
Ppp2r2bGOBP_Regulation_Of_Protein_Modification_ProcessMouseBrainrep_32.2e-188
Ppp2r2bGOBP_Peptidyl_Serine_DephosphorylationMouseBrainrep_5 6.6e-35
Ppp2r2bGOBP_Peptidyl_Serine_DephosphorylationMouseEmbryorep_14 2.4e-15
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseEmbryorep_14 8.5e-07
Ppp2r2bGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseEmbryorep_14 6.3e-12
Ppp2r2bGOBP_Protein_DephosphorylationMouseEmbryorep_1 1.2e-29
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseKidneyNep 1.3e-36
Ppp2r2bGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseKidneyNep 4.6e-22
Ppp2r2bGOBP_Regulation_Of_Protein_Modification_ProcessMouseKidneyNep 4.6e-22
Ppp2r2bGOBP_DephosphorylationMouseKidneyrep_2 1.4e-90
Ppp2r2bGOBP_Peptidyl_Serine_DephosphorylationMouseKidneyrep_2 7.3e-40
Ppp2r2bGOBP_Protein_DephosphorylationMouseKidneyrep_2 2.0e-69
Ppp2r2bGOBP_Regulation_Of_DephosphorylationMouseKidneyrep_2 1.8e-67
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseKidneyrep_2 1.4e-60
Ppp2r2bGOBP_Regulation_Of_Phosphatase_ActivityMouseKidneyrep_2 2.5e-75
Ppp2r2bGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseKidneyrep_2 8.2e-73
Ppp2r2bGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseKidneyrep_2 1.3e-41
Ppp2r2bGOBP_Regulation_Of_Protein_DephosphorylationMouseKidneyrep_2 1.4e-61
Ppp2r2bGOBP_Regulation_Of_Protein_Modification_ProcessMouseKidneyrep_2 2.2e-44
Ppp2r2bGOBP_Regulation_Of_DephosphorylationMouseLiverCN16-E1 1.3e-11
Ppp2r2bGOBP_Regulation_Of_Protein_DephosphorylationMouseLiverCN16-E1 9.7e-13
Ppp2r2bGOBP_DephosphorylationMouseLymphMS-1 3.6e-12
Ppp2r2bGOBP_Peptidyl_Serine_DephosphorylationMouseLymphMS-1 1.8e-08
Ppp2r2bGOBP_Protein_DephosphorylationMouseLymphMS-1 2.7e-12
Ppp2r2bGOBP_Regulation_Of_DephosphorylationMouseLymphMS-1 3.0e-12
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseLymphMS-1 1.9e-08
Ppp2r2bGOBP_Regulation_Of_Phosphatase_ActivityMouseLymphMS-1 6.8e-12
Ppp2r2bGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseLymphMS-1 4.9e-09
Ppp2r2bGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseLymphMS-1 5.6e-12
Ppp2r2bGOBP_Regulation_Of_Protein_DephosphorylationMouseLymphMS-1 1.1e-09
Ppp2r2bGOBP_Regulation_Of_Protein_Modification_ProcessMouseLymphMS-1 1.9e-12
Ppp2r2bGOBP_DephosphorylationMouseBrainHP_ad_rep7 3.9e-08
Ppp2r2bGOBP_Regulation_Of_Phosphatase_ActivityMouseBrainHP_ad_rep7 4.1e-07
Ppp2r2bGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseBrainHP_ad_rep7 1.7e-08
Ppp2r2bGOBP_Regulation_Of_Protein_Modification_ProcessMouseBrainHP_ad_rep7 1.1e-07
Ppp2r2bGOBP_Regulation_Of_Hydrolase_ActivityMouseBrainHP_polb_rep9 6.0e-09
Ppp2r2bGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseBrainHP_polb_rep9 9.3e-07
Ppp2r2bGOBP_Peptidyl_Serine_DephosphorylationMouseBrainHP_wt_rep2 1.0e-07

Top

Ppp2r2b function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

Top

Ppp2r2b function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

Top

Transcription factor for Ppp2r2b envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

Top

Related Drugs for Ppp2r2b

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for Ppp2r2b

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Ppp2r2bC0087012Ataxia, Spinocerebellar1CTD_human
Ppp2r2bC0752120Spinocerebellar Ataxia Type 11CTD_human
Ppp2r2bC0752121Spinocerebellar Ataxia Type 21CTD_human
Ppp2r2bC0752122Spinocerebellar Ataxia Type 41CTD_human
Ppp2r2bC0752123Spinocerebellar Ataxia Type 51CTD_human
Ppp2r2bC0752124Spinocerebellar Ataxia Type 6 (disorder)1CTD_human
Ppp2r2bC0752125Spinocerebellar Ataxia Type 71CTD_human