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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pard3b (spascer ID:72823)

Gene summary for Pard3b

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pard3b
	Gene ID	72823
	Gene name	par-3 family cell polarity regulator beta
	Synonyms	1810008K04Rik\|2010002N16Rik\|2810455B10Rik\|Als2cr19\|PAR3B\|PAR3L\|PAR3beta
	Cytomap	1\|1 C2
	Type of gene	protein-coding
	Description	partitioning defective 3 homolog BDN-276O13.2PAR3-L proteinamyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein homologpar-3 partitioning defective 3 homolog Bpartitioning defective 3-like protein
	Modification date	20220424
	UniProtAcc	Q9CSB4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pard3b	GO:0000226	microtubule cytoskeleton organization	21873635	Process
Pard3b	GO:0005912	adherens junction	21873635	Component
Pard3b	GO:0005938	cell cortex	21873635	Component
Pard3b	GO:0007155	cell adhesion	21873635	Process
Pard3b	GO:0008104	protein localization	21873635	Process
Pard3b	GO:0016324	apical plasma membrane	21873635	Component
Pard3b	GO:0030010	establishment of cell polarity	21873635	Process
Pard3b	GO:0035091	phosphatidylinositol binding	21873635	Function
Pard3b	GO:0043296	apical junction complex	21873635	Component
Pard3b	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	21873635	Process
Pard3b	GO:0051660	establishment of centrosome localization	21873635	Process

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Spatial pattern events for Pard3b

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pard3b	Mouse	Embryo	1F	34210887	1.88e-08
Pard3b	Mouse	Embryo	1G	34210887	1.77e-08
Pard3b	Mouse	Embryo	2G	34210887	1.33e-08
Pard3b	Mouse	Embryo	2H	34210887	4.00e-12
Pard3b	Mouse	Embryo	4C	34210887	6.22e-11
Pard3b	Mouse	Embryo	4D	34210887	5.88e-06
Pard3b	Mouse	Embryo	4E	34210887	1.45e-12
Pard3b	Mouse	Brain	rep_1	35027729	2.18e-10
Pard3b	Mouse	Brain	rep_3	35027729	3.46e-07
Pard3b	Mouse	Brain	rep_4	35027729	2.53e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E

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Spatial pattern pathway has Pard3b envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pard3b	GOBP_Cell_Cycle	Mouse	Spinal cord	CN94_E1	1.1e-06
Pard3b	GOBP_Microtubule_Based_Process	Mouse	Spinal cord	CN94_E1	2.4e-06
Pard3b	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Pard3b	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Pard3b	GOBP_Cell_Division	Mouse	Spinal cord	L7CN45_C1	2.6e-06
Pard3b	GOBP_Establishment_Of_Organelle_Localization	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Spinal cord	L7CN45_C1	2.6e-06
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Spinal cord	L7CN45_C1	4.7e-06
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Spinal cord	L7CN45_C1	2.6e-07
Pard3b	GOBP_Organelle_Localization	Mouse	Spinal cord	L7CN45_C1	1.4e-08
Pard3b	GOBP_Cell_Cycle	Mouse	Brain	rep_27	8.4e-07
Pard3b	GOBP_Cell_Division	Mouse	Brain	rep_27	3.6e-05
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Brain	rep_37	5.0e-06
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Brain	rep_41	9.9e-06
Pard3b	GOBP_Cell_Cycle	Mouse	Brain	rep_1	7.0e-10
Pard3b	GOBP_Cell_Division	Mouse	Brain	rep_1	9.7e-23
Pard3b	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Pard3b	GOBP_Establishment_Of_Organelle_Localization	Mouse	Brain	rep_1	1.4e-37
Pard3b	GOBP_Microtubule_Based_Process	Mouse	Brain	rep_1	1.6e-07
Pard3b	GOBP_Organelle_Localization	Mouse	Brain	rep_1	1.6e-45
Pard3b	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Pard3b	GOBP_Establishment_Of_Cell_Polarity	Mouse	Brain	rep_3	1.0e-112
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Brain	rep_3	1.3e-52
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Brain	rep_3	2.0e-64
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Brain	rep_3	6.8e-85
Pard3b	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-140
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Brain	rep_3	1.7e-69
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Embryo	rep_6	6.8e-17
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Embryo	rep_14	8.5e-29
Pard3b	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Pard3b	GOBP_Cell_Division	Mouse	Embryo	rep_1	0.0e+00
Pard3b	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Pard3b	GOBP_Cell_Cycle	Mouse	Kidney	rep_2	1.0e-24
Pard3b	GOBP_Cell_Division	Mouse	Kidney	rep_2	5.3e-77
Pard3b	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Pard3b	GOBP_Establishment_Of_Organelle_Localization	Mouse	Kidney	rep_2	6.6e-67
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Kidney	rep_2	5.1e-33
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Kidney	rep_2	9.7e-10
Pard3b	GOBP_Organelle_Localization	Mouse	Kidney	rep_2	2.9e-72
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Liver	CN16-D2	2.0e-07
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Liver	CN16-D2	3.2e-07
Pard3b	GOBP_Microtubule_Based_Process	Mouse	Liver	CN16-D2	1.8e-11
Pard3b	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Liver	CN16-D2	2.8e-10
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Liver	CN16-E1	3.0e-07
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Liver	CN65-D1	3.5e-12
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Liver	rep_15	5.2e-22
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Liver	rep_15	4.7e-07
Pard3b	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Pard3b	GOBP_Organelle_Localization	Mouse	Liver	rep_16	2.2e-21
Pard3b	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Pard3b	GOBP_Cell_Cycle	Mouse	Lymph	MS-1	1.3e-07
Pard3b	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Lymph	MS-1	9.6e-16
Pard3b	GOBP_Establishment_Of_Organelle_Localization	Mouse	Lymph	MS-1	8.3e-07
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Lymph	MS-1	6.3e-09
Pard3b	GOBP_Microtubule_Based_Process	Mouse	Lymph	MS-1	1.5e-08
Pard3b	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Lymph	MS-1	7.6e-07
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Lymph	MS-1	1.0e-08
Pard3b	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Pard3b	GOBP_Establishment_Of_Organelle_Localization	Mouse	Brain	rep_4	1.2e-42
Pard3b	GOBP_Organelle_Localization	Mouse	Brain	rep_4	3.3e-19
Pard3b	GOBP_Cell_Cycle	Mouse	Brain	HP_ad_rep7	6.6e-08
Pard3b	GOBP_Cell_Division	Mouse	Brain	HP_ad_rep7	2.6e-09
Pard3b	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Pard3b	GOBP_Establishment_Of_Cell_Polarity	Mouse	Brain	HP_ad_rep7	2.0e-07
Pard3b	GOBP_Establishment_Of_Centrosome_Localization	Mouse	Brain	HP_ad_rep7	1.7e-18
Pard3b	GOBP_Establishment_Of_Organelle_Localization	Mouse	Brain	HP_ad_rep7	4.5e-08
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Bipolar_Cell_Polarity	Mouse	Brain	HP_ad_rep7	3.0e-09
Pard3b	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Brain	HP_ad_rep7	4.1e-10
Pard3b	GOBP_Microtubule_Based_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Pard3b	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	3.8e-13
Pard3b	GOBP_Microtubule_Organizing_Center_Localization	Mouse	Brain	HP_ad_rep7	9.9e-10
Pard3b	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Pard3b	GOBP_Organelle_Localization	Mouse	Brain	HP_polb_rep9	1.7e-09

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Pard3b function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pard3b function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pard3b envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pard3b

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pard3b

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Pard3b	C1535926	Neurodevelopmental Disorders	1	CTD_human