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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pygo1 (spascer ID:72135)

Gene summary for Pygo1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pygo1
	Gene ID	72135
	Gene name	pygopus 1
	Synonyms	2600014C22Rik
	Cytomap	9\|9 D
	Type of gene	protein-coding
	Description	pygopus homolog 1
	Modification date	20220424
	UniProtAcc	Q9D0P5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pygo1	GO:0001822	kidney development	21873635	Process
Pygo1	GO:0007289	spermatid nucleus differentiation	21873635	Process

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Spatial pattern events for Pygo1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pygo1	Mouse	Brain	S1	34413515	2.07e-15
Pygo1	Mouse	Brain	S2	34413515	2.85e-15
Pygo1	Mouse	Brain	S4	34413515	7.61e-10
Pygo1	Mouse	Brain	S6	34413515	1.46e-15
Pygo1	Mouse	Brain	S7	34413515	1.90e-14
Pygo1	Mouse	Embryo	rep_3	33188776	3.93e-10
Pygo1	Mouse	Embryo	rep_4	33188776	4.16e-06
Pygo1	Mouse	Embryo	rep_5	33188776	6.41e-08
Pygo1	Mouse	Embryo	rep_13	33188776	5.32e-06
Pygo1	Mouse	Brain	rep_1	33469025	2.37e-15
Pygo1	Mouse	Brain	rep_1	35027729	5.00e-13
Pygo1	Mouse	Brain	rep_2	35027729	2.83e-15
Pygo1	Mouse	Brain	rep_3	35027729	2.24e-11
Pygo1	Mouse	Brain	rep_4	35027729	8.31e-09
Pygo1	Mouse	Brain	rep_5	35027729	2.62e-15
Pygo1	Mouse	Brain	rep_5	35210624	3.30e-10
Pygo1	Mouse	Brain	rep_7	35210624	7.69e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Pygo1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pygo1	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Spinal cord	CN94_E1	3.2e-07
Pygo1	GOBP_Gamete_Generation	Mouse	Spinal cord	CN94_E1	3.1e-07
Pygo1	GOBP_Germ_Cell_Development	Mouse	Spinal cord	CN94_E1	6.4e-06
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Spinal cord	CN94_E1	1.5e-06
Pygo1	GOBP_Male_Gamete_Generation	Mouse	Spinal cord	CN94_E1	4.7e-06
Pygo1	GOBP_Protein_Localization_To_Nucleus	Mouse	Spinal cord	CN94_E1	2.3e-06
Pygo1	GOBP_Reproduction	Mouse	Spinal cord	CN94_E1	7.8e-08
Pygo1	GOBP_Urogenital_System_Development	Mouse	Spinal cord	CN94_E1	2.7e-06
Pygo1	GOBP_Spermatid_Differentiation	Mouse	Spinal cord	L7bCN02_E1	2.4e-06
Pygo1	GOBP_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Pygo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	5.6e-07
Pygo1	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Spinal cord	L7CN45_C1	8.6e-09
Pygo1	GOBP_Immune_System_Development	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Pygo1	GOBP_Nucleus_Organization	Mouse	Spinal cord	L7CN45_C1	1.1e-08
Pygo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Pygo1	GOBP_Protein_Localization_To_Organelle	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Pygo1	GOBP_Spermatid_Nucleus_Differentiation	Mouse	Spinal cord	L7CN47_C1	7.0e-08
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Spinal cord	L8CN17_E1	1.6e-07
Pygo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Spinal cord	L8CN17_E1	3.7e-07
Pygo1	GOBP_Gamete_Generation	Mouse	Brain	rep_27	5.2e-05
Pygo1	GOBP_Germ_Cell_Development	Mouse	Brain	rep_27	9.0e-05
Pygo1	GOBP_Urogenital_System_Development	Mouse	Brain	rep_27	1.1e-05
Pygo1	GOBP_Spermatid_Nucleus_Differentiation	Mouse	Brain	rep_75	2.9e-06
Pygo1	GOBP_Cell_Cell_Signaling	Mouse	Brain	rep_1	5.1e-48
Pygo1	GOBP_Nucleus_Organization	Mouse	Brain	rep_1	8.3e-09
Pygo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Pygo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Pygo1	GOBP_Spermatid_Nucleus_Differentiation	Mouse	Brain	rep_1	8.8e-15
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Brain	rep_3	5.3e-174
Pygo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Brain	rep_3	2.0e-124
Pygo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Brain	rep_3	3.3e-46
Pygo1	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Brain	rep_3	3.6e-171
Pygo1	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Brain	rep_3	2.9e-159
Pygo1	GOBP_Gamete_Generation	Mouse	Brain	rep_3	1.3e-194
Pygo1	GOBP_Germ_Cell_Development	Mouse	Brain	rep_3	7.6e-194
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Brain	rep_3	2.4e-153
Pygo1	GOBP_Immune_System_Development	Mouse	Brain	rep_3	1.3e-52
Pygo1	GOBP_Male_Gamete_Generation	Mouse	Brain	rep_3	1.6e-190
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Brain	rep_3	1.2e-58
Pygo1	GOBP_Protein_Localization_To_Nucleus	Mouse	Brain	rep_3	1.1e-167
Pygo1	GOBP_Protein_Localization_To_Organelle	Mouse	Brain	rep_3	6.3e-172
Pygo1	GOBP_Reproduction	Mouse	Brain	rep_3	3.4e-125
Pygo1	GOBP_Spermatid_Differentiation	Mouse	Brain	rep_3	1.1e-186
Pygo1	GOBP_Urogenital_System_Development	Mouse	Brain	rep_3	2.4e-187
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Embryo	rep_14	1.1e-07
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Embryo	rep_14	4.3e-09
Pygo1	GOBP_Gamete_Generation	Mouse	Embryo	rep_14	6.5e-07
Pygo1	GOBP_Germ_Cell_Development	Mouse	Embryo	rep_14	2.1e-19
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Embryo	rep_14	1.1e-18
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Embryo	rep_14	5.9e-07
Pygo1	GOBP_Spermatid_Nucleus_Differentiation	Mouse	Embryo	rep_14	2.8e-25
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Embryo	rep_1	2.6e-12
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Embryo	rep_1	0.0e+00
Pygo1	GOBP_Immune_System_Development	Mouse	Embryo	rep_1	0.0e+00
Pygo1	GOBP_Male_Gamete_Generation	Mouse	Embryo	rep_1	0.0e+00
Pygo1	GOBP_Urogenital_System_Development	Mouse	Embryo	rep_1	1.8e-45
Pygo1	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Pygo1	GOBP_Germ_Cell_Development	Mouse	Embryo	rep_2	2.4e-67
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Embryo	rep_3	6.9e-27
Pygo1	GOBP_Gamete_Generation	Mouse	Embryo	rep_3	2.1e-220
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Embryo	rep_3	8.7e-222
Pygo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Pygo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Pygo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Embryo	rep_6	1.7e-33
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Kidney	rep_2	2.0e-101
Pygo1	GOBP_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.2e-72
Pygo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Kidney	rep_2	2.1e-78
Pygo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.7e-89
Pygo1	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Kidney	rep_2	1.1e-18
Pygo1	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Kidney	rep_2	3.6e-46
Pygo1	GOBP_Gamete_Generation	Mouse	Kidney	rep_2	5.0e-33
Pygo1	GOBP_Germ_Cell_Development	Mouse	Kidney	rep_2	1.5e-12
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Kidney	rep_2	7.1e-56
Pygo1	GOBP_Immune_System_Development	Mouse	Kidney	rep_2	4.6e-22
Pygo1	GOBP_Male_Gamete_Generation	Mouse	Kidney	rep_2	5.8e-51
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Kidney	rep_2	1.6e-53
Pygo1	GOBP_Nucleus_Organization	Mouse	Kidney	rep_2	3.9e-53
Pygo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Pygo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Pygo1	GOBP_Protein_Localization_To_Nucleus	Mouse	Kidney	rep_2	1.4e-52
Pygo1	GOBP_Protein_Localization_To_Organelle	Mouse	Kidney	rep_2	3.4e-44
Pygo1	GOBP_Reproduction	Mouse	Kidney	rep_2	9.0e-46
Pygo1	GOBP_Spermatid_Nucleus_Differentiation	Mouse	Kidney	rep_2	1.4e-50
Pygo1	GOBP_Urogenital_System_Development	Mouse	Kidney	rep_2	2.5e-57
Pygo1	GOBP_Immune_System_Development	Mouse	Liver	CN73-C1	2.2e-07
Pygo1	GOBP_Immune_System_Development	Mouse	Liver	rep_16	5.3e-11
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Lymph	MS-1	8.5e-09
Pygo1	GOBP_Cell_Cell_Signaling	Mouse	Lymph	MS-1	9.7e-11
Pygo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Lymph	MS-1	7.3e-10
Pygo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Lymph	MS-1	1.6e-11
Pygo1	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Lymph	MS-1	2.1e-08
Pygo1	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Lymph	MS-1	2.2e-10
Pygo1	GOBP_Gamete_Generation	Mouse	Lymph	MS-1	7.7e-08
Pygo1	GOBP_Germ_Cell_Development	Mouse	Lymph	MS-1	4.9e-12
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Lymph	MS-1	1.6e-16
Pygo1	GOBP_Immune_System_Development	Mouse	Lymph	MS-1	1.2e-13
Pygo1	GOBP_Male_Gamete_Generation	Mouse	Lymph	MS-1	1.6e-08
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Pygo1	GOBP_Nucleus_Organization	Mouse	Lymph	MS-1	2.5e-09
Pygo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Pygo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Pygo1	GOBP_Protein_Localization_To_Nucleus	Mouse	Lymph	MS-1	3.2e-15
Pygo1	GOBP_Protein_Localization_To_Organelle	Mouse	Lymph	MS-1	1.4e-09
Pygo1	GOBP_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Pygo1	GOBP_Spermatid_Differentiation	Mouse	Lymph	MS-1	4.7e-08
Pygo1	GOBP_Urogenital_System_Development	Mouse	Lymph	MS-1	5.4e-09
Pygo1	GOBP_Reproduction	Mouse	Lung	rep_1	9.6e-12
Pygo1	GOBP_Urogenital_System_Development	Mouse	Brain	rep_7	8.1e-17
Pygo1	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	1.2e-07
Pygo1	GOBP_Cell_Cell_Signaling	Mouse	Brain	HP_ad_rep7	1.6e-08
Pygo1	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Pygo1	GOBP_Cellular_Process_Involved_In_Reproduction_In_Multicellular_Organism	Mouse	Brain	HP_ad_rep7	6.0e-15
Pygo1	GOBP_Developmental_Process_Involved_In_Reproduction	Mouse	Brain	HP_ad_rep7	2.5e-08
Pygo1	GOBP_Gamete_Generation	Mouse	Brain	HP_ad_rep7	1.3e-11
Pygo1	GOBP_Germ_Cell_Development	Mouse	Brain	HP_ad_rep7	3.3e-13
Pygo1	GOBP_Immune_System_Development	Mouse	Brain	HP_ad_rep7	8.3e-09
Pygo1	GOBP_Multicellular_Organism_Reproduction	Mouse	Brain	HP_ad_rep7	6.1e-08
Pygo1	GOBP_Nucleus_Organization	Mouse	Brain	HP_ad_rep7	2.6e-09
Pygo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Pygo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11
Pygo1	GOBP_Protein_Localization_To_Organelle	Mouse	Brain	HP_ad_rep7	4.8e-12
Pygo1	GOBP_Reproduction	Mouse	Brain	HP_ad_rep7	7.9e-09
Pygo1	GOBP_Spermatid_Differentiation	Mouse	Brain	HP_ad_rep7	1.5e-12
Pygo1	GOBP_Spermatid_Nucleus_Differentiation	Mouse	Brain	HP_ad_rep7	2.0e-10
Pygo1	GOBP_Urogenital_System_Development	Mouse	Brain	HP_ad_rep7	3.6e-14
Pygo1	GOBP_Male_Gamete_Generation	Mouse	Brain	HP_ad_rep8	8.4e-07
Pygo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Brain	HP_polb_rep9	1.7e-14
Pygo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Brain	HP_polb_rep9	1.2e-14
Pygo1	GOBP_Hematopoietic_Progenitor_Cell_Differentiation	Mouse	Brain	HP_polb_rep9	1.2e-18
Pygo1	GOBP_Protein_Localization_To_Nucleus	Mouse	Brain	HP_polb_rep9	2.3e-09

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Pygo1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pygo1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pygo1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pygo1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pygo1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source