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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Amer2 (spascer ID:72125)

Gene summary for Amer2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Amer2
	Gene ID	72125
	Gene name	APC membrane recruitment 2
	Synonyms	2600011E07Rik\|Fam123a
	Cytomap	14\|14 D1
	Type of gene	protein-coding
	Description	APC membrane recruitment protein 2family with sequence similarity 123, member Aprotein FAM123A
	Modification date	20220424
	UniProtAcc	Q8CCJ4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Amer2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	21873635	Function
Amer2	GO:0005886	plasma membrane	21873635	Component
Amer2	GO:0008013	beta-catenin binding	21873635	Function
Amer2	GO:0060828	regulation of canonical Wnt signaling pathway	21873635	Process

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Spatial pattern events for Amer2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Amer2	Mouse	Brain	S4	34413515	9.97e-06
Amer2	Mouse	Embryo	4E	34210887	4.53e-15
Amer2	Mouse	Brain	rep_1	33469025	1.30e-15
Amer2	Mouse	Brain	rep_1	35027729	9.52e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_1_H&E

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Spatial pattern pathway has Amer2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Amer2	GOBP_Ectoderm_Development	Mouse	Spinal cord	L7bCN02_E1	9.0e-06
Amer2	GOBP_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Amer2	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	5.6e-07
Amer2	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	4.8e-06
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	4.8e-06
Amer2	GOBP_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.2e-06
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Spinal cord	L8CN17_E1	1.6e-07
Amer2	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Spinal cord	L8CN17_E1	3.7e-07
Amer2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Spinal cord	L8CN17_E1	8.3e-06
Amer2	GOBP_Ectoderm_Development	Mouse	Brain	rep_21	2.3e-05
Amer2	GOBP_Cell_Cell_Signaling	Mouse	Brain	rep_1	5.1e-48
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Brain	rep_3	5.3e-174
Amer2	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Brain	rep_3	2.0e-124
Amer2	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Brain	rep_3	3.3e-46
Amer2	GOBP_Ectoderm_Development	Mouse	Brain	rep_3	6.8e-80
Amer2	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Mouse	Brain	rep_3	2.3e-180
Amer2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	rep_3	1.3e-138
Amer2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	rep_3	7.8e-106
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Brain	rep_3	4.4e-159
Amer2	GOBP_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Brain	rep_3	1.7e-164
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Embryo	rep_14	1.1e-07
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Embryo	rep_14	5.8e-09
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Embryo	rep_1	2.6e-12
Amer2	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Mouse	Embryo	rep_1	6.8e-306
Amer2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Embryo	rep_1	1.1e-25
Amer2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Embryo	rep_1	5.6e-10
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Embryo	rep_1	2.0e-10
Amer2	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Embryo	rep_6	1.7e-33
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Kidney	rep_2	2.0e-101
Amer2	GOBP_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.2e-72
Amer2	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Kidney	rep_2	2.1e-78
Amer2	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.7e-89
Amer2	GOBP_Ectoderm_Development	Mouse	Kidney	rep_2	6.8e-60
Amer2	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Mouse	Kidney	rep_2	1.3e-49
Amer2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Kidney	rep_2	1.7e-39
Amer2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Kidney	rep_2	4.0e-40
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Kidney	rep_2	2.4e-65
Amer2	GOBP_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Kidney	rep_2	5.2e-90
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Liver	CN16-E1	1.5e-08
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Liver	rep_16	3.3e-07
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Lymph	MS-1	8.5e-09
Amer2	GOBP_Cell_Cell_Signaling	Mouse	Lymph	MS-1	9.7e-11
Amer2	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Lymph	MS-1	7.3e-10
Amer2	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Lymph	MS-1	1.6e-11
Amer2	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Mouse	Lymph	MS-1	9.4e-09
Amer2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Lymph	MS-1	1.5e-11
Amer2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Lymph	MS-1	1.0e-14
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Lymph	MS-1	9.3e-09
Amer2	GOBP_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Lymph	MS-1	6.2e-07
Amer2	GOBP_Canonical_Wnt_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	1.2e-07
Amer2	GOBP_Cell_Cell_Signaling	Mouse	Brain	HP_ad_rep7	1.6e-08
Amer2	GOBP_Ectoderm_Development	Mouse	Brain	HP_ad_rep7	3.4e-09
Amer2	GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	4.0e-07
Amer2	GOBP_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	3.8e-08
Amer2	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Brain	HP_polb_rep9	1.7e-14
Amer2	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Brain	HP_polb_rep9	1.2e-14
Amer2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	HP_polb_rep9	3.1e-09
Amer2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.4e-11
Amer2	GOBP_Negative_Regulation_Of_Wnt_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	4.7e-20

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Amer2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Amer2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Amer2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Amer2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Amer2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source