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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Tpx2 (spascer ID:72119)

Gene summary for Tpx2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Tpx2
	Gene ID	72119
	Gene name	TPX2, microtubule-associated
	Synonyms	2610005B21Rik\|DIL2\|REPP86\|p100
	Cytomap	2\|2 H1
	Type of gene	protein-coding
	Description	targeting protein for Xklp2TPX2, microtubule-associated protein homolog
	Modification date	20220424
	UniProtAcc	A2APB8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Tpx2	GO:0005880	nuclear microtubule	21873635	Component
Tpx2	GO:0008017	microtubule binding	21873635	Function
Tpx2	GO:0030295	protein kinase activator activity	21873635	Function
Tpx2	GO:0072686	mitotic spindle	21873635	Component
Tpx2	GO:0090307	mitotic spindle assembly	21873635	Process

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Spatial pattern events for Tpx2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Tpx2	Mouse	Embryo	1F	34210887	9.74e-06
Tpx2	Mouse	Embryo	2H	34210887	1.42e-09
Tpx2	Mouse	Embryo	4E	34210887	4.11e-12
Tpx2	Mouse	Embryo	rep_2	33188776	9.50e-12
Tpx2	Mouse	Embryo	rep_3	33188776	3.28e-14
Tpx2	Mouse	Embryo	rep_5	33188776	2.41e-13
Tpx2	Mouse	Embryo	rep_13	33188776	4.49e-15
Tpx2	Mouse	Kidney	rep_5	34853151	5.45e-15
Tpx2	Mouse	Brain	rep_1	33469025	1.30e-15
Tpx2	Mouse	Lymph	A1	0	3.29e-15
Tpx2	Mouse	Lymph	B1	0	3.66e-15
Tpx2	Mouse	Lung	rep_1	35290801	4.52e-15
Tpx2	Mouse	Lung	rep_2	35290801	3.33e-11
Tpx2	Mouse	Lung	rep_3	35290801	4.52e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_5_H&E
Brain_rep_1_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Tpx2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Tpx2	GOBP_Cell_Cycle	Mouse	Spinal cord	CN94_E1	1.1e-06
Tpx2	GOBP_Cell_Cycle_Process	Mouse	Spinal cord	CN94_E1	3.8e-06
Tpx2	GOBP_Microtubule_Based_Process	Mouse	Spinal cord	CN94_E1	2.4e-06
Tpx2	GOBP_Mitotic_Nuclear_Division	Mouse	Spinal cord	CN94_E1	7.7e-06
Tpx2	GOBP_Mitotic_Spindle_Assembly	Mouse	Spinal cord	CN94_E1	1.2e-06
Tpx2	GOBP_Mitotic_Spindle_Organization	Mouse	Spinal cord	CN94_E1	3.7e-06
Tpx2	GOBP_Organelle_Assembly	Mouse	Spinal cord	CN94_E1	9.5e-06
Tpx2	GOBP_Organelle_Fission	Mouse	Spinal cord	CN94_E1	1.2e-06
Tpx2	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Mouse	Spinal cord	CN94_E1	5.6e-06
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Spinal cord	CN94_E1	7.8e-06
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Spinal cord	CN94_E1	5.1e-06
Tpx2	GOBP_Positive_Regulation_Of_Transferase_Activity	Mouse	Spinal cord	CN94_E1	7.9e-07
Tpx2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Spinal cord	CN94_E1	5.8e-06
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Mouse	Spinal cord	CN94_E1	3.3e-06
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Process	Mouse	Spinal cord	CN94_E1	7.5e-07
Tpx2	GOBP_Cell_Cycle_Phase_Transition	Mouse	Spinal cord	L7bCN02_E1	1.5e-06
Tpx2	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Tpx2	GOBP_Activation_Of_Protein_Kinase_Activity	Mouse	Spinal cord	L7CN45_C1	9.3e-06
Tpx2	GOBP_Cell_Division	Mouse	Spinal cord	L7CN45_C1	2.6e-06
Tpx2	GOBP_Cellular_Component_Disassembly	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis	Mouse	Spinal cord	L7CN45_C1	1.3e-06
Tpx2	GOBP_Mitotic_Cell_Cycle	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Tpx2	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Tpx2	GOBP_Negative_Regulation_Of_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	4.1e-06
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Tpx2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Tpx2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Tpx2	GOBP_Regulation_Of_Cell_Cycle	Mouse	Spinal cord	L7CN45_C1	3.0e-07
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Spinal cord	L7CN45_C1	5.9e-07
Tpx2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Tpx2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	8.1e-06
Tpx2	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Mouse	Spinal cord	L7CN45_C1	5.4e-08
Tpx2	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Tpx2	GOBP_Regulation_Of_Spindle_Organization	Mouse	Spinal cord	L7CN45_C1	4.6e-08
Tpx2	GOBP_Cell_Cycle_G2_M_Phase_Transition	Mouse	Spinal cord	L7CN47_C1	3.3e-07
Tpx2	GOBP_Regulation_Of_Microtubule_Depolymerization	Mouse	Spinal cord	L7CN47_C1	6.8e-06
Tpx2	GOBP_Microtubule_Depolymerization	Mouse	Spinal cord	L7CN47_D1	1.5e-06
Tpx2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Spinal cord	L8CN11_C1	3.6e-13
Tpx2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Tpx2	GOBP_Regulation_Of_Protein_Kinase_Activity	Mouse	Spinal cord	L8CN17_E1	5.8e-07
Tpx2	GOBP_Regulation_Of_Transferase_Activity	Mouse	Spinal cord	L8CN17_E1	9.1e-06
Tpx2	GOBP_Cell_Cycle	Mouse	Brain	rep_27	8.4e-07
Tpx2	GOBP_Cell_Division	Mouse	Brain	rep_27	3.6e-05
Tpx2	GOBP_Mitotic_Cell_Cycle	Mouse	Brain	rep_27	1.1e-05
Tpx2	GOBP_Protein_Depolymerization	Mouse	Brain	rep_27	3.6e-06
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Process	Mouse	Brain	rep_27	4.4e-08
Tpx2	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Mouse	Brain	rep_27	7.4e-07
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Brain	rep_27	3.0e-05
Tpx2	GOBP_Regulation_Of_Protein_Kinase_Activity	Mouse	Brain	rep_27	2.9e-05
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	rep_27	5.2e-05
Tpx2	GOBP_Regulation_Of_Transferase_Activity	Mouse	Brain	rep_27	1.1e-06
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Brain	rep_37	6.9e-05
Tpx2	GOBP_Spindle_Organization	Mouse	Brain	rep_41	1.3e-05
Tpx2	GOBP_Cell_Cycle	Mouse	Brain	rep_1	7.0e-10
Tpx2	GOBP_Cell_Cycle_G2_M_Phase_Transition	Mouse	Brain	rep_1	8.5e-51
Tpx2	GOBP_Cell_Cycle_Phase_Transition	Mouse	Brain	rep_1	1.6e-31
Tpx2	GOBP_Cell_Cycle_Process	Mouse	Brain	rep_1	6.7e-14
Tpx2	GOBP_Cell_Division	Mouse	Brain	rep_1	9.7e-23
Tpx2	GOBP_Cellular_Component_Disassembly	Mouse	Brain	rep_1	1.5e-15
Tpx2	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Tpx2	GOBP_Microtubule_Based_Process	Mouse	Brain	rep_1	1.6e-07
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis	Mouse	Brain	rep_1	1.4e-11
Tpx2	GOBP_Microtubule_Depolymerization	Mouse	Brain	rep_1	5.5e-19
Tpx2	GOBP_Microtubule_Nucleation	Mouse	Brain	rep_1	3.3e-40
Tpx2	GOBP_Microtubule_Polymerization	Mouse	Brain	rep_1	2.7e-31
Tpx2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_1	6.8e-20
Tpx2	GOBP_Mitotic_Cell_Cycle	Mouse	Brain	rep_1	1.5e-25
Tpx2	GOBP_Mitotic_Spindle_Organization	Mouse	Brain	rep_1	9.2e-11
Tpx2	GOBP_Negative_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-38
Tpx2	GOBP_Negative_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_1	2.7e-19
Tpx2	GOBP_Negative_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	8.5e-21
Tpx2	GOBP_Negative_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Brain	rep_1	2.2e-35
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Brain	rep_1	1.3e-08
Tpx2	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Mouse	Brain	rep_1	6.7e-10
Tpx2	GOBP_Positive_Regulation_Of_Transferase_Activity	Mouse	Brain	rep_1	1.5e-08
Tpx2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Brain	rep_1	4.1e-29
Tpx2	GOBP_Protein_Depolymerization	Mouse	Brain	rep_1	6.9e-18
Tpx2	GOBP_Protein_Polymerization	Mouse	Brain	rep_1	3.4e-38
Tpx2	GOBP_Regulation_Of_Cell_Cycle	Mouse	Brain	rep_1	3.9e-14
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Brain	rep_1	4.2e-12
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Process	Mouse	Brain	rep_1	4.4e-18
Tpx2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-40
Tpx2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Brain	rep_1	2.0e-17
Tpx2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_1	4.8e-24
Tpx2	GOBP_Regulation_Of_Microtubule_Depolymerization	Mouse	Brain	rep_1	1.0e-19
Tpx2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_1	7.9e-26
Tpx2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	7.9e-20
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Brain	rep_1	1.3e-36
Tpx2	GOBP_Regulation_Of_Protein_Depolymerization	Mouse	Brain	rep_1	2.0e-20
Tpx2	GOBP_Regulation_Of_Protein_Kinase_Activity	Mouse	Brain	rep_1	5.2e-10
Tpx2	GOBP_Regulation_Of_Spindle_Organization	Mouse	Brain	rep_1	9.4e-11
Tpx2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Brain	rep_1	3.5e-07
Tpx2	GOBP_Spindle_Organization	Mouse	Brain	rep_1	3.4e-10
Tpx2	GOBP_Activation_Of_Protein_Kinase_Activity	Mouse	Brain	rep_3	7.5e-137
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-140
Tpx2	GOBP_Mitotic_Nuclear_Division	Mouse	Brain	rep_3	2.2e-190
Tpx2	GOBP_Mitotic_Spindle_Assembly	Mouse	Brain	rep_3	2.0e-140
Tpx2	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	rep_3	4.4e-113
Tpx2	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	1.0e-83
Tpx2	GOBP_Organelle_Assembly	Mouse	Brain	rep_3	2.0e-160
Tpx2	GOBP_Organelle_Fission	Mouse	Brain	rep_3	8.1e-189
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	8.5e-79
Tpx2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	rep_3	2.6e-94
Tpx2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_3	9.9e-174
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Brain	rep_3	2.9e-128
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	rep_3	6.0e-108
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Mouse	Brain	rep_3	3.1e-201
Tpx2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Tpx2	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Mouse	Brain	rep_3	1.7e-200
Tpx2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Brain	rep_3	3.0e-62
Tpx2	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Brain	rep_3	2.2e-188
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	rep_3	8.6e-94
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Brain	rep_3	1.2e-89
Tpx2	GOBP_Regulation_Of_Transferase_Activity	Mouse	Brain	rep_3	4.6e-186
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Brain	rep_3	6.9e-120
Tpx2	GOBP_Spindle_Assembly	Mouse	Brain	rep_3	1.4e-179
Tpx2	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	6.7e-78
Tpx2	GOBP_Activation_Of_Protein_Kinase_Activity	Mouse	Embryo	rep_14	1.8e-08
Tpx2	GOBP_Microtubule_Nucleation	Mouse	Embryo	rep_14	6.0e-09
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Embryo	rep_14	1.3e-11
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Mouse	Embryo	rep_14	3.3e-08
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Embryo	rep_14	9.5e-37
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Embryo	rep_14	6.6e-44
Tpx2	GOBP_Cell_Division	Mouse	Embryo	rep_1	0.0e+00
Tpx2	GOBP_Negative_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Embryo	rep_1	2.4e-89
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.2e-98
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Embryo	rep_1	9.7e-27
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Embryo	rep_1	2.2e-69
Tpx2	GOBP_Protein_Depolymerization	Mouse	Embryo	rep_1	1.8e-18
Tpx2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Embryo	rep_1	2.6e-63
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Embryo	rep_1	1.8e-18
Tpx2	GOBP_Regulation_Of_Protein_Depolymerization	Mouse	Embryo	rep_1	1.8e-18
Tpx2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_1	1.3e-102
Tpx2	GOBP_Activation_Of_Protein_Kinase_Activity	Mouse	Embryo	rep_2	9.0e-34
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis	Mouse	Embryo	rep_2	0.0e+00
Tpx2	GOBP_Positive_Regulation_Of_Transferase_Activity	Mouse	Embryo	rep_2	1.1e-280
Tpx2	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Embryo	rep_3	2.7e-07
Tpx2	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Mouse	Embryo	rep_3	4.2e-94
Tpx2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Embryo	rep_3	1.3e-27
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Embryo	rep_3	4.8e-13
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Embryo	rep_3	2.8e-65
Tpx2	GOBP_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_3	0.0e+00
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Embryo	rep_5	1.2e-28
Tpx2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Embryo	rep_5	4.2e-125
Tpx2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Embryo	rep_5	4.2e-125
Tpx2	GOBP_Cell_Cycle_G2_M_Phase_Transition	Mouse	Embryo	rep_6	1.2e-274
Tpx2	GOBP_Organelle_Assembly	Mouse	Embryo	rep_6	4.1e-70
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Embryo	rep_6	1.2e-274
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	Nep	1.8e-46
Tpx2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	1.8e-46
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Tpx2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	Nep	4.3e-38
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	Nep	4.2e-26
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Kidney	Nep	4.2e-26
Tpx2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Kidney	Nep	4.6e-22
Tpx2	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	Nep	4.6e-22
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Kidney	Nep	4.6e-22
Tpx2	GOBP_Activation_Of_Protein_Kinase_Activity	Mouse	Kidney	rep_2	6.9e-34
Tpx2	GOBP_Cell_Cycle	Mouse	Kidney	rep_2	1.0e-24
Tpx2	GOBP_Cell_Cycle_G2_M_Phase_Transition	Mouse	Kidney	rep_2	8.2e-89
Tpx2	GOBP_Cell_Cycle_Phase_Transition	Mouse	Kidney	rep_2	6.8e-67
Tpx2	GOBP_Cell_Cycle_Process	Mouse	Kidney	rep_2	3.0e-21
Tpx2	GOBP_Cell_Division	Mouse	Kidney	rep_2	5.3e-77
Tpx2	GOBP_Cellular_Component_Disassembly	Mouse	Kidney	rep_2	4.2e-70
Tpx2	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Tpx2	GOBP_Microtubule_Depolymerization	Mouse	Kidney	rep_2	1.6e-59
Tpx2	GOBP_Mitotic_Cell_Cycle	Mouse	Kidney	rep_2	1.1e-15
Tpx2	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Kidney	rep_2	8.7e-59
Tpx2	GOBP_Negative_Regulation_Of_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.1e-44
Tpx2	GOBP_Negative_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Kidney	rep_2	3.4e-61
Tpx2	GOBP_Negative_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	1.5e-119
Tpx2	GOBP_Negative_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Kidney	rep_2	1.2e-78
Tpx2	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	3.6e-76
Tpx2	GOBP_Organelle_Assembly	Mouse	Kidney	rep_2	2.8e-62
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	2.1e-66
Tpx2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.2e-45
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-12
Tpx2	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Mouse	Kidney	rep_2	1.3e-43
Tpx2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-43
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	rep_2	7.3e-67
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Kidney	rep_2	8.4e-58
Tpx2	GOBP_Positive_Regulation_Of_Transferase_Activity	Mouse	Kidney	rep_2	1.1e-59
Tpx2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Kidney	rep_2	1.4e-54
Tpx2	GOBP_Protein_Depolymerization	Mouse	Kidney	rep_2	1.4e-17
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Kidney	rep_2	6.1e-79
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Mouse	Kidney	rep_2	4.2e-70
Tpx2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.8e-22
Tpx2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Tpx2	GOBP_Regulation_Of_Microtubule_Depolymerization	Mouse	Kidney	rep_2	6.9e-55
Tpx2	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Mouse	Kidney	rep_2	3.2e-49
Tpx2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	6.7e-77
Tpx2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Kidney	rep_2	1.3e-41
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Kidney	rep_2	7.2e-105
Tpx2	GOBP_Regulation_Of_Protein_Depolymerization	Mouse	Kidney	rep_2	2.6e-110
Tpx2	GOBP_Regulation_Of_Protein_Kinase_Activity	Mouse	Kidney	rep_2	1.0e-67
Tpx2	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	rep_2	2.2e-44
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Kidney	rep_2	1.8e-44
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Kidney	rep_2	4.2e-64
Tpx2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.1e-54
Tpx2	GOBP_Regulation_Of_Transferase_Activity	Mouse	Kidney	rep_2	7.3e-90
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Kidney	rep_2	1.0e-97
Tpx2	GOBP_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.5e-65
Tpx2	GOBP_Microtubule_Based_Process	Mouse	Liver	CN16-D2	1.8e-11
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Liver	CN16-D2	2.8e-10
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis	Mouse	Liver	CN16-D2	1.1e-08
Tpx2	GOBP_Mitotic_Spindle_Assembly	Mouse	Liver	CN16-D2	1.4e-10
Tpx2	GOBP_Mitotic_Spindle_Organization	Mouse	Liver	CN16-D2	7.7e-10
Tpx2	GOBP_Protein_Depolymerization	Mouse	Liver	CN16-D2	9.8e-08
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Liver	CN16-D2	1.2e-08
Tpx2	GOBP_Regulation_Of_Protein_Depolymerization	Mouse	Liver	CN16-D2	2.4e-07
Tpx2	GOBP_Spindle_Assembly	Mouse	Liver	CN16-D2	6.4e-09
Tpx2	GOBP_Spindle_Organization	Mouse	Liver	CN16-D2	3.8e-08
Tpx2	GOBP_Cell_Cycle_G2_M_Phase_Transition	Mouse	Liver	CN16-E1	4.3e-09
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Liver	CN16-E1	1.4e-11
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Liver	CN16-E1	1.6e-18
Tpx2	GOBP_Microtubule_Nucleation	Mouse	Liver	CN65-C1	8.5e-12
Tpx2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Liver	CN65-C1	6.4e-09
Tpx2	GOBP_Microtubule_Depolymerization	Mouse	Liver	rep_15	4.5e-10
Tpx2	GOBP_Regulation_Of_Microtubule_Depolymerization	Mouse	Liver	rep_15	1.2e-11
Tpx2	GOBP_Regulation_Of_Spindle_Organization	Mouse	Liver	rep_15	1.2e-14
Tpx2	GOBP_Microtubule_Nucleation	Mouse	Liver	rep_16	1.1e-11
Tpx2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Liver	rep_16	7.4e-11
Tpx2	GOBP_Mitotic_Nuclear_Division	Mouse	Liver	rep_16	7.7e-07
Tpx2	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Liver	rep_16	1.3e-07
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Liver	rep_16	1.4e-09
Tpx2	GOBP_Protein_Polymerization	Mouse	Liver	rep_16	3.0e-07
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Mouse	Liver	rep_16	9.0e-07
Tpx2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Liver	rep_16	7.8e-13
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Liver	rep_16	1.4e-13
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Liver	rep_16	2.8e-11
Tpx2	GOBP_Cell_Cycle	Mouse	Lymph	MS-1	1.3e-07
Tpx2	GOBP_Cellular_Component_Disassembly	Mouse	Lymph	MS-1	2.4e-16
Tpx2	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Tpx2	GOBP_Microtubule_Based_Process	Mouse	Lymph	MS-1	1.5e-08
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Lymph	MS-1	7.6e-07
Tpx2	GOBP_Microtubule_Polymerization	Mouse	Lymph	MS-1	5.1e-08
Tpx2	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Lymph	MS-1	3.7e-11
Tpx2	GOBP_Negative_Regulation_Of_Cytoskeleton_Organization	Mouse	Lymph	MS-1	2.9e-09
Tpx2	GOBP_Negative_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	4.9e-09
Tpx2	GOBP_Negative_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Lymph	MS-1	8.0e-15
Tpx2	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	3.9e-11
Tpx2	GOBP_Organelle_Assembly	Mouse	Lymph	MS-1	5.5e-08
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Tpx2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	1.9e-12
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Lymph	MS-1	5.6e-12
Tpx2	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Mouse	Lymph	MS-1	7.7e-08
Tpx2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Mouse	Lymph	MS-1	1.9e-12
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Lymph	MS-1	1.9e-12
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Lymph	MS-1	2.7e-14
Tpx2	GOBP_Positive_Regulation_Of_Transferase_Activity	Mouse	Lymph	MS-1	1.1e-10
Tpx2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Lymph	MS-1	5.5e-11
Tpx2	GOBP_Protein_Depolymerization	Mouse	Lymph	MS-1	8.7e-15
Tpx2	GOBP_Protein_Polymerization	Mouse	Lymph	MS-1	8.7e-08
Tpx2	GOBP_Regulation_Of_Cell_Cycle	Mouse	Lymph	MS-1	6.4e-09
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Process	Mouse	Lymph	MS-1	4.1e-08
Tpx2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Lymph	MS-1	8.4e-09
Tpx2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Tpx2	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Mouse	Lymph	MS-1	6.9e-07
Tpx2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	1.4e-10
Tpx2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Lymph	MS-1	5.6e-12
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Lymph	MS-1	4.4e-18
Tpx2	GOBP_Regulation_Of_Protein_Depolymerization	Mouse	Lymph	MS-1	1.8e-15
Tpx2	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Lymph	MS-1	1.9e-12
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Lymph	MS-1	1.4e-12
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Lymph	MS-1	1.0e-13
Tpx2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	4.3e-11
Tpx2	GOBP_Regulation_Of_Transferase_Activity	Mouse	Lymph	MS-1	1.0e-08
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Lymph	MS-1	3.2e-10
Tpx2	GOBP_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	1.5e-12
Tpx2	GOBP_Microtubule_Depolymerization	Mouse	Brain	rep_4	2.1e-40
Tpx2	GOBP_Negative_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_4	4.1e-10
Tpx2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Brain	rep_4	2.3e-16
Tpx2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_4	2.6e-09
Tpx2	GOBP_Regulation_Of_Microtubule_Depolymerization	Mouse	Brain	rep_4	8.4e-19
Tpx2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_4	3.0e-27
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis	Mouse	Brain	rep_7	1.4e-09
Tpx2	GOBP_Cell_Cycle	Mouse	Brain	HP_ad_rep7	6.6e-08
Tpx2	GOBP_Cell_Cycle_G2_M_Phase_Transition	Mouse	Brain	HP_ad_rep7	3.1e-07
Tpx2	GOBP_Cell_Cycle_Phase_Transition	Mouse	Brain	HP_ad_rep7	4.9e-09
Tpx2	GOBP_Cell_Cycle_Process	Mouse	Brain	HP_ad_rep7	1.7e-09
Tpx2	GOBP_Cell_Division	Mouse	Brain	HP_ad_rep7	2.6e-09
Tpx2	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Tpx2	GOBP_Microtubule_Based_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	3.8e-13
Tpx2	GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis	Mouse	Brain	HP_ad_rep7	1.2e-13
Tpx2	GOBP_Microtubule_Depolymerization	Mouse	Brain	HP_ad_rep7	2.2e-21
Tpx2	GOBP_Microtubule_Nucleation	Mouse	Brain	HP_ad_rep7	1.9e-21
Tpx2	GOBP_Microtubule_Polymerization	Mouse	Brain	HP_ad_rep7	6.4e-15
Tpx2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	HP_ad_rep7	7.6e-16
Tpx2	GOBP_Mitotic_Nuclear_Division	Mouse	Brain	HP_ad_rep7	2.0e-09
Tpx2	GOBP_Mitotic_Spindle_Assembly	Mouse	Brain	HP_ad_rep7	6.5e-10
Tpx2	GOBP_Mitotic_Spindle_Organization	Mouse	Brain	HP_ad_rep7	2.9e-12
Tpx2	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	HP_ad_rep7	2.6e-08
Tpx2	GOBP_Negative_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	6.1e-08
Tpx2	GOBP_Negative_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Brain	HP_ad_rep7	3.9e-09
Tpx2	GOBP_Organelle_Fission	Mouse	Brain	HP_ad_rep7	1.1e-08
Tpx2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	2.8e-07
Tpx2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	2.8e-07
Tpx2	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.7e-07
Tpx2	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Mouse	Brain	HP_ad_rep7	3.5e-08
Tpx2	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	HP_ad_rep7	2.8e-07
Tpx2	GOBP_Positive_Regulation_Of_Transferase_Activity	Mouse	Brain	HP_ad_rep7	2.2e-07
Tpx2	GOBP_Regulation_Of_Cell_Cycle	Mouse	Brain	HP_ad_rep7	1.6e-08
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Mouse	Brain	HP_ad_rep7	7.6e-13
Tpx2	GOBP_Regulation_Of_Cell_Cycle_Process	Mouse	Brain	HP_ad_rep7	9.9e-08
Tpx2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Brain	HP_ad_rep7	3.2e-13
Tpx2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	8.7e-15
Tpx2	GOBP_Regulation_Of_Microtubule_Depolymerization	Mouse	Brain	HP_ad_rep7	3.7e-09
Tpx2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	HP_ad_rep7	5.7e-18
Tpx2	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Mouse	Brain	HP_ad_rep7	3.4e-10
Tpx2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	8.1e-07
Tpx2	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.7e-08
Tpx2	GOBP_Regulation_Of_Protein_Kinase_Activity	Mouse	Brain	HP_ad_rep7	2.3e-09
Tpx2	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Brain	HP_ad_rep7	1.1e-07
Tpx2	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	HP_ad_rep7	4.0e-09
Tpx2	GOBP_Regulation_Of_Spindle_Organization	Mouse	Brain	HP_ad_rep7	7.5e-17
Tpx2	GOBP_Regulation_Of_Transferase_Activity	Mouse	Brain	HP_ad_rep7	1.6e-08
Tpx2	GOBP_Spindle_Organization	Mouse	Brain	HP_ad_rep7	1.6e-12
Tpx2	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	HP_ad_rep7	5.2e-07
Tpx2	GOBP_Negative_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	HP_adpolb_rep1	2.2e-07
Tpx2	GOBP_Organelle_Assembly	Mouse	Brain	HP_adpolb_rep1	1.8e-07
Tpx2	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Mouse	Brain	HP_adpolb_rep1	7.8e-09
Tpx2	GOBP_Regulation_Of_Signal_Transduction_By_P53_Class_Mediator	Mouse	Brain	HP_adpolb_rep1	1.2e-12
Tpx2	GOBP_Signal_Transduction_By_P53_Class_Mediator	Mouse	Brain	HP_adpolb_rep1	5.9e-12
Tpx2	GOBP_Cellular_Component_Disassembly	Mouse	Brain	HP_polb_rep9	3.4e-08
Tpx2	GOBP_Mitotic_Cell_Cycle	Mouse	Brain	HP_polb_rep9	1.6e-10
Tpx2	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.0e-11
Tpx2	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Mouse	Brain	HP_polb_rep9	9.8e-11
Tpx2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Brain	HP_polb_rep9	1.8e-08
Tpx2	GOBP_Protein_Depolymerization	Mouse	Brain	HP_polb_rep9	3.3e-09
Tpx2	GOBP_Protein_Polymerization	Mouse	Brain	HP_polb_rep9	5.9e-08
Tpx2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.1e-07
Tpx2	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Tpx2	GOBP_Regulation_Of_Protein_Containing_Complex_Disassembly	Mouse	Brain	HP_polb_rep9	4.4e-08
Tpx2	GOBP_Regulation_Of_Protein_Depolymerization	Mouse	Brain	HP_polb_rep9	1.8e-11
Tpx2	GOBP_Spindle_Assembly	Mouse	Brain	HP_polb_rep9	8.0e-11

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Tpx2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Tpx2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Tpx2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Tpx2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Tpx2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Tpx2	C2239176	Liver carcinoma	1	CTD_human