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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Aopep (spascer ID:72061)

Gene summary for Aopep

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Aopep
	Gene ID	72061
	Gene name	aminopeptidase O
	Synonyms	2010111I01Rik\|2300006M17Rik\|AP-O\|AW742919\|ApO\|mir-23b\|mir-24-1\|mir-27b
	Cytomap	13\|13 B3
	Type of gene	protein-coding
	Description	aminopeptidase O
	Modification date	20220424
	UniProtAcc	Q8BXQ6

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Aopep	GO:0005730	nucleolus	21873635	Component

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Spatial pattern events for Aopep

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Aopep	Mouse	Brain	S1	34413515	1.31e-09
Aopep	Mouse	Brain	S2	34413515	1.56e-15
Aopep	Mouse	Brain	S3	34413515	1.64e-15
Aopep	Mouse	Brain	S4	34413515	6.10e-14
Aopep	Mouse	Brain	S6	34413515	1.46e-15
Aopep	Mouse	Brain	S7	34413515	1.55e-15
Aopep	Mouse	Brain	rep_1	35141374	2.02e-15
Aopep	Mouse	Brain	rep_2	35141374	2.51e-10
Aopep	Mouse	Brain	rep_3	35141374	1.64e-15
Aopep	Mouse	Brain	rep_4	35141374	1.57e-15
Aopep	Mouse	Brain	rep_5	35141374	2.43e-06
Aopep	Mouse	Brain	rep_6	35141374	4.42e-10
Aopep	Mouse	Kidney	rep_1	34853151	4.13e-15
Aopep	Mouse	Lymph	PBS	0	2.06e-10
Aopep	Mouse	Lymph	A1	0	2.81e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_rep_1_H&E

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Spatial pattern pathway has Aopep envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Spinal cord	CN93_D2	2.2e-06
Aopep	GOBP_Endocrine_Process	Mouse	Spinal cord	CN94_E1	3.0e-07
Aopep	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Circulatory_Renin_Angiotensin	Mouse	Spinal cord	CN94_E1	9.8e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Spinal cord	CN94_E1	1.3e-06
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	5.0e-06
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Renin_Angiotensin	Mouse	Spinal cord	L7bCN02_E1	6.2e-06
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Spinal cord	L7bCN02_E1	8.0e-06
Aopep	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Aopep	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Aopep	GOBP_Protein_Processing	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Aopep	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Aopep	GOBP_Regulation_Of_Hormone_Levels	Mouse	Spinal cord	L7CN45_C1	9.1e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Spinal cord	L7CN47_C2	1.1e-06
Aopep	GOBP_Circulatory_System_Process	Mouse	Spinal cord	L8CN17_E1	2.2e-06
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Renin_Angiotensin	Mouse	Brain	rep_19	1.2e-05
Aopep	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Aopep	GOBP_Circulatory_System_Process	Mouse	Brain	rep_3	2.0e-61
Aopep	GOBP_Endocrine_Process	Mouse	Brain	rep_3	8.9e-13
Aopep	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Aopep	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
Aopep	GOBP_Protein_Processing	Mouse	Brain	rep_3	2.3e-168
Aopep	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Brain	rep_3	1.9e-11
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Circulatory_Renin_Angiotensin	Mouse	Brain	rep_3	2.0e-56
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Brain	rep_3	8.2e-81
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Renin_Angiotensin	Mouse	Brain	rep_3	1.3e-24
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Brain	rep_3	9.6e-61
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Brain	rep_3	5.0e-111
Aopep	GOBP_Endocrine_Process	Mouse	Embryo	rep_6	8.8e-10
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Embryo	rep_6	5.1e-09
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_6	2.4e-08
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Embryo	rep_6	9.8e-11
Aopep	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-11
Aopep	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Aopep	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
Aopep	GOBP_Protein_Processing	Mouse	Embryo	rep_14	4.6e-22
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Embryo	rep_14	1.6e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Circulatory_Renin_Angiotensin	Mouse	Embryo	rep_14	5.8e-37
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Embryo	rep_14	3.2e-36
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Renin_Angiotensin	Mouse	Embryo	rep_14	2.3e-38
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Embryo	rep_14	2.3e-51
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Embryo	rep_1	0.0e+00
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_1	1.5e-209
Aopep	GOBP_Regulation_Of_Hormone_Levels	Mouse	Embryo	rep_1	4.1e-102
Aopep	GOBP_Circulatory_System_Process	Mouse	Kidney	IRI	1.5e-08
Aopep	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
Aopep	GOBP_Protein_Processing	Mouse	Kidney	IRI	4.8e-57
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Kidney	IRI	1.0e-08
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Kidney	IRI	9.0e-58
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	IRI	2.4e-84
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Circulatory_Renin_Angiotensin	Mouse	Kidney	IRI	8.6e-10
Aopep	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Aopep	GOBP_Protein_Processing	Mouse	Kidney	rep_1	8.0e-08
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Kidney	rep_1	2.1e-07
Aopep	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Aopep	GOBP_Circulatory_System_Process	Mouse	Kidney	rep_2	1.4e-100
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Kidney	rep_2	6.4e-55
Aopep	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Aopep	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
Aopep	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Aopep	GOBP_Regulation_Of_Hormone_Levels	Mouse	Kidney	rep_2	6.8e-73
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	rep_2	3.9e-99
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Kidney	rep_4	2.4e-08
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Kidney	rep_4	1.8e-09
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Renin_Angiotensin	Mouse	Kidney	rep_4	3.5e-10
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Kidney	rep_4	2.3e-09
Aopep	GOBP_Endocrine_Process	Mouse	Liver	rep_16	4.8e-29
Aopep	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
Aopep	GOBP_Protein_Processing	Mouse	Liver	rep_16	3.8e-09
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Liver	rep_16	2.3e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Liver	rep_16	9.5e-13
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Liver	rep_16	1.1e-19
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Renin_Angiotensin	Mouse	Liver	rep_16	5.8e-19
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Liver	rep_16	3.8e-18
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Liver	rep_16	3.5e-13
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Intestine	rep_2	1.8e-28
Aopep	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Aopep	GOBP_Circulatory_System_Process	Mouse	Lymph	MS-1	3.9e-08
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-08
Aopep	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Aopep	GOBP_Protein_Processing	Mouse	Lymph	MS-1	8.5e-10
Aopep	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Lymph	MS-1	2.6e-08
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Lymph	MS-1	2.5e-11
Aopep	GOBP_Regulation_Of_Hormone_Levels	Mouse	Lymph	MS-1	1.6e-16
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Lymph	MS-1	7.2e-08
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Circulatory_Renin_Angiotensin	Mouse	Lymph	MS-1	8.2e-13
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Lymph	MS-1	3.0e-09
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Lymph	PBS	1.0e-07
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Brain	rep_4	1.7e-08
Aopep	GOBP_Regulation_Of_Angiotensin_Levels_In_Blood	Mouse	Brain	rep_7	5.8e-16
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Brain	rep_7	7.3e-13
Aopep	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Aopep	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Aopep	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Brain	HP_ad_rep8	6.2e-07
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Brain	HP_ad_rep8	1.9e-07
Aopep	GOBP_Endocrine_Process	Mouse	Brain	HP_adpolb_rep1	3.9e-13
Aopep	GOBP_Regulation_Of_Blood_Pressure	Mouse	Brain	HP_adpolb_rep1	3.1e-08
Aopep	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Brain	HP_adpolb_rep1	3.0e-08
Aopep	GOBP_Signaling_Receptor_Ligand_Precursor_Processing	Mouse	Brain	HP_adpolb_rep4	9.8e-07
Aopep	GOBP_Circulatory_System_Process	Mouse	Brain	HP_polb_rep9	5.3e-09
Aopep	GOBP_Hormone_Metabolic_Process	Mouse	Brain	HP_polb_rep9	3.2e-09
Aopep	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
Aopep	GOBP_Protein_Processing	Mouse	Brain	HP_polb_rep9	1.6e-12
Aopep	GOBP_Regulation_Of_Hormone_Levels	Mouse	Brain	HP_polb_rep9	9.1e-09

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Aopep function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Aopep function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Aopep envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Aopep

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Aopep

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source