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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ttll7 (spascer ID:70892)

Gene summary for Ttll7

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ttll7
	Gene ID	70892
	Gene name	tubulin tyrosine ligase-like family, member 7
	Synonyms	1110049N09Rik\|4921517B04Rik\|C630030B20\|mTTLL7
	Cytomap	3\|3 H2
	Type of gene	protein-coding
	Description	tubulin polyglutamylase TTLL7polyglutamylasetubulin--tyrosine ligase-like protein 7
	Modification date	20220510
	UniProtAcc	A4Q9F0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ttll7	GO:0000226	microtubule cytoskeleton organization	21873635	Process
Ttll7	GO:0005929	cilium	21873635	Component
Ttll7	GO:0015631	tubulin binding	21873635	Function
Ttll7	GO:0018095	protein polyglutamylation	21873635	Process
Ttll7	GO:0070740	tubulin-glutamic acid ligase activity	21873635	Function

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Spatial pattern events for Ttll7

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ttll7	Mouse	Brain	S1	34413515	2.07e-15
Ttll7	Mouse	Brain	S2	34413515	1.56e-15
Ttll7	Mouse	Brain	S3	34413515	1.64e-15
Ttll7	Mouse	Brain	S4	34413515	1.37e-15
Ttll7	Mouse	Brain	S6	34413515	1.46e-15
Ttll7	Mouse	Brain	S7	34413515	1.55e-15
Ttll7	Mouse	Brain	11A	32637622	6.70e-06
Ttll7	Mouse	Brain	14B	32637622	2.47e-09
Ttll7	Mouse	Brain	16A	32637622	1.50e-08
Ttll7	Mouse	Brain	17A	32637622	9.82e-12
Ttll7	Mouse	Brain	17B	32637622	5.15e-10
Ttll7	Mouse	Brain	18A	32637622	4.03e-12
Ttll7	Mouse	Brain	18B	32637622	1.64e-12
Ttll7	Mouse	Brain	19A	32637622	4.38e-07
Ttll7	Mouse	Brain	19B	32637622	1.60e-12
Ttll7	Mouse	Brain	20A	32637622	1.50e-10
Ttll7	Mouse	Brain	20B	32637622	6.29e-09
Ttll7	Mouse	Brain	21A	32637622	2.30e-14
Ttll7	Mouse	Brain	21B	32637622	2.26e-14
Ttll7	Mouse	Brain	22A	32637622	8.87e-15
Ttll7	Mouse	Brain	22B	32637622	8.81e-15
Ttll7	Mouse	Brain	23A	32637622	1.51e-10
Ttll7	Mouse	Brain	23B	32637622	1.10e-14
Ttll7	Mouse	Brain	24A	32637622	2.45e-14
Ttll7	Mouse	Brain	24B	32637622	3.94e-14
Ttll7	Mouse	Brain	25A	32637622	5.01e-14
Ttll7	Mouse	Brain	26A	32637622	6.69e-09
Ttll7	Mouse	Brain	27A	32637622	1.15e-12
Ttll7	Mouse	Brain	27B	32637622	6.05e-11
Ttll7	Mouse	Brain	28A	32637622	1.86e-14
Ttll7	Mouse	Brain	28B	32637622	3.87e-14
Ttll7	Mouse	Brain	29A	32637622	1.82e-14
Ttll7	Mouse	Brain	29B	32637622	1.91e-14
Ttll7	Mouse	Brain	31A	32637622	4.37e-07
Ttll7	Mouse	Brain	34A	32637622	4.12e-10
Ttll7	Mouse	Brain	36A	32637622	1.01e-07
Ttll7	Mouse	Brain	36B	32637622	4.78e-06
Ttll7	Mouse	Brain	39A	32637622	4.24e-06
Ttll7	Mouse	Brain	rep_1	35141374	2.02e-15
Ttll7	Mouse	Brain	rep_2	35141374	1.69e-15
Ttll7	Mouse	Brain	rep_3	35141374	1.64e-15
Ttll7	Mouse	Brain	rep_4	35141374	1.57e-15
Ttll7	Mouse	Brain	rep_5	35141374	1.47e-15
Ttll7	Mouse	Brain	rep_6	35141374	1.73e-15
Ttll7	Mouse	Embryo	rep_2	33188776	6.67e-07
Ttll7	Mouse	Brain	rep_1	33469025	1.30e-15
Ttll7	Mouse	Brain	rep_1	35027729	1.66e-15
Ttll7	Mouse	Brain	rep_2	35027729	1.57e-15
Ttll7	Mouse	Brain	rep_3	35027729	1.32e-15
Ttll7	Mouse	Brain	rep_4	35027729	1.76e-15
Ttll7	Mouse	Brain	rep_5	35027729	1.46e-15
Ttll7	Mouse	Brain	B02_D1	32702314	1.06e-07
Ttll7	Mouse	Brain	B04_E1	32702314	8.42e-11
Ttll7	Mouse	Brain	B05_D2	32702314	7.75e-14
Ttll7	Mouse	Brain	B05_E2	32702314	4.11e-14
Ttll7	Mouse	Brain	N02_C1	32702314	4.07e-10
Ttll7	Mouse	Brain	N02_D1	32702314	2.44e-14
Ttll7	Mouse	Brain	N03_D2	32702314	3.36e-10
Ttll7	Mouse	Brain	N05_C2	32702314	1.01e-13
Ttll7	Mouse	Brain	N05_D2	32702314	1.93e-14
Ttll7	Mouse	Testicle	rep_5	34731600	1.12e-10
Ttll7	Mouse	Brain	rep_1	35210624	1.74e-15
Ttll7	Mouse	Brain	rep_2	35210624	1.74e-15
Ttll7	Mouse	Brain	rep_3	35210624	1.82e-15
Ttll7	Mouse	Brain	rep_4	35210624	1.19e-10
Ttll7	Mouse	Brain	rep_5	35210624	3.62e-15
Ttll7	Mouse	Brain	rep_6	35210624	8.98e-09
Ttll7	Mouse	Brain	rep_7	35210624	6.25e-15
Ttll7	Mouse	Brain	OFB_adpolb_rep4	33083725	9.45e-03

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B04_E1_H&E
Brain_B05_D2_H&E
Brain_B05_E2_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_D2_H&E
Brain_N05_C2_H&E
Brain_N05_D2_H&E
Brain_OFB_adpolb_rep4_H&E

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Spatial pattern pathway has Ttll7 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ttll7	GOBP_Microtubule_Based_Process	Mouse	Spinal cord	CN94_E1	2.4e-06
Ttll7	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Ttll7	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Spinal cord	L7CN47_C1	5.3e-07
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Spinal cord	L7CN47_C1	5.6e-06
Ttll7	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Ttll7	GOBP_Microtubule_Based_Process	Mouse	Brain	rep_1	1.6e-07
Ttll7	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Brain	rep_1	9.0e-07
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Brain	rep_1	1.0e-09
Ttll7	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-140
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Brain	rep_3	2.4e-48
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Embryo	rep_14	1.2e-13
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Embryo	rep_14	7.2e-32
Ttll7	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Embryo	rep_3	0.0e+00
Ttll7	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Ttll7	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Kidney	rep_2	6.9e-23
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Kidney	rep_2	1.1e-124
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Kidney	rep_2	1.4e-17
Ttll7	GOBP_Microtubule_Based_Process	Mouse	Liver	CN16-D2	1.8e-11
Ttll7	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Liver	CN16-D2	2.8e-10
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Liver	CN16-E1	4.2e-09
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Liver	CN16-E1	1.0e-11
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Liver	rep_15	6.1e-13
Ttll7	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Ttll7	GOBP_Microtubule_Based_Process	Mouse	Lymph	MS-1	1.5e-08
Ttll7	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Lymph	MS-1	7.6e-07
Ttll7	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Lymph	MS-1	1.2e-13
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Lymph	MS-1	6.0e-09
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Lung	rep_1	2.7e-13
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Brain	rep_7	4.9e-09
Ttll7	GOBP_Protein_Polyglutamylation	Mouse	Brain	rep_7	1.3e-35
Ttll7	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Ttll7	GOBP_Microtubule_Based_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Ttll7	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	3.8e-13
Ttll7	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Brain	HP_ad_rep7	3.2e-08
Ttll7	GOBP_Peptidyl_Glutamic_Acid_Modification	Mouse	Brain	HP_ad_rep7	1.0e-10

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Ttll7 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ttll7 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ttll7 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ttll7

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ttll7

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source