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Spatial pattern gene: Thap3 (spascer ID:69876) |
Gene summary for Thap3 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Thap3 | Gene ID | 69876 |
| Gene name | THAP domain containing, apoptosis associated protein 3 |
| Synonyms | 2010013E08Rik|2210418H06Rik |
| Cytomap | 4|4 E2 |
| Type of gene | protein-coding |
| Description | THAP domain-containing protein 3snoRNA MBI-15 |
| Modification date | 20220424 |
| UniProtAcc | Q8BJ25 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
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Spatial pattern events for Thap3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Thap3 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Thap3 | Mouse | Brain | S7 | 34413515 | 1.75e-08 |
| Thap3 | Mouse | Brain | rep_3 | 35141374 | 3.30e-12 |
| Thap3 | Mouse | Brain | rep_4 | 35141374 | 3.84e-07 |
| Thap3 | Mouse | Kidney | CLP | 34003797 | 6.16e-10 |
| Thap3 | Mouse | Kidney | rep_1 | 34853151 | 3.60e-09 |
| Thap3 | Mouse | Brain | rep_1 | 33469025 | 2.24e-09 |
| Thap3 | Mouse | Brain | rep_1 | 35027729 | 7.10e-09 |
| Thap3 | Mouse | Brain | rep_2 | 35027729 | 8.08e-09 |
| Thap3 | Mouse | Brain | rep_3 | 35027729 | 2.75e-07 |
| Thap3 | Mouse | Brain | rep_4 | 35027729 | 1.89e-06 |
| Thap3 | Mouse | Brain | rep_5 | 35027729 | 2.43e-11 |
| Thap3 | Mouse | Intestine | rep_4 | 35149721 | 6.90e-12 |
| Thap3 | Mouse | Brain | rep_2 | 35210624 | 1.39e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_rep_1_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Thap3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Thap3 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Thap3 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | rep_1 | 2.5e-12 |
| Thap3 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | rep_1 | 1.6e-17 |
| Thap3 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Embryo | rep_3 | 0.0e+00 |
| Thap3 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Embryo | rep_3 | 0.0e+00 |
| Thap3 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Kidney | rep_2 | 4.5e-10 |
| Thap3 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Kidney | rep_2 | 8.3e-40 |
| Thap3 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Lymph | MS-1 | 4.4e-12 |
| Thap3 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Lymph | MS-1 | 1.7e-12 |
| Thap3 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-11 |
| Thap3 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | HP_ad_rep7 | 7.3e-11 |
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Thap3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Thap3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Thap3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Thap3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Thap3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Thap3 | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| Thap3 | C1136382 | Sclerocystic Ovaries | 1 | CTD_human |
