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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Vars2 (spascer ID:68915)

Gene summary for Vars2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Vars2
	Gene ID	68915
	Gene name	valyl-tRNA synthetase 2, mitochondrial
	Synonyms	1190004I24Rik\|Vars2l\|mKIAA1885
	Cytomap	17\|17 B1
	Type of gene	protein-coding
	Description	valine--tRNA ligase, mitochondrialvalRSvalyl-tRNA synthetase 2, mitochondrial (putative)valyl-tRNA synthetase, mitochondrial
	Modification date	20220424
	UniProtAcc	Q3U2A8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Vars2	GO:0004832	valine-tRNA ligase activity	21873635	Function
Vars2	GO:0005829	cytosol	21873635	Component
Vars2	GO:0006438	valyl-tRNA aminoacylation	21873635	Process

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Spatial pattern events for Vars2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Vars2	Mouse	Brain	S2	34413515	1.14e-07
Vars2	Mouse	Brain	S4	34413515	3.37e-07
Vars2	Mouse	Kidney	IRI	34003797	2.29e-15
Vars2	Mouse	Kidney	rep_4	34853151	7.51e-07
Vars2	Mouse	Intestine	rep_4	35149721	4.72e-10
Vars2	Mouse	Testicle	rep_4	34731600	3.42e-10
Vars2	Mouse	Lymph	A1	0	1.13e-07
Vars2	Mouse	Lung	rep_4	35290801	5.96e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E
Kidney_rep_4_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Vars2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.5e-07
Vars2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Vars2	GOBP_Amide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Vars2	GOBP_Amino_Acid_Activation	Mouse	Spinal cord	L7CN45_C1	1.9e-07
Vars2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Vars2	GOBP_Ncrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Vars2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Vars2	GOBP_Peptide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Vars2	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Vars2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Vars2	GOBP_Trna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Vars2	GOBP_Regulation_Of_Translational_Fidelity	Mouse	Spinal cord	L7CN47_D1	7.4e-06
Vars2	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	rep_3	2.5e-86
Vars2	GOBP_Amino_Acid_Activation	Mouse	Brain	rep_3	5.9e-107
Vars2	GOBP_Aminoacyl_Trna_Metabolism_Involved_In_Translational_Fidelity	Mouse	Brain	rep_3	6.9e-147
Vars2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	8.5e-191
Vars2	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	rep_3	1.8e-46
Vars2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Vars2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Vars2	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	rep_3	2.1e-69
Vars2	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Vars2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Vars2	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_3	2.5e-229
Vars2	GOBP_Regulation_Of_Translational_Fidelity	Mouse	Brain	rep_7	2.6e-47
Vars2	GOBP_Amide_Biosynthetic_Process	Mouse	Embryo	rep_14	3.7e-18
Vars2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Vars2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Vars2	GOBP_Peptide_Biosynthetic_Process	Mouse	Embryo	rep_14	2.8e-15
Vars2	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Vars2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Vars2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Vars2	GOBP_Amide_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-84
Vars2	GOBP_Amino_Acid_Activation	Mouse	Kidney	rep_2	4.4e-95
Vars2	GOBP_Aminoacyl_Trna_Metabolism_Involved_In_Translational_Fidelity	Mouse	Kidney	rep_2	3.8e-72
Vars2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-34
Vars2	GOBP_Ncrna_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-81
Vars2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Vars2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Vars2	GOBP_Peptide_Biosynthetic_Process	Mouse	Kidney	rep_2	2.9e-85
Vars2	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Vars2	GOBP_Regulation_Of_Translational_Fidelity	Mouse	Kidney	rep_2	7.9e-87
Vars2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Vars2	GOBP_Trna_Metabolic_Process	Mouse	Kidney	rep_2	1.9e-92
Vars2	GOBP_Aminoacyl_Trna_Metabolism_Involved_In_Translational_Fidelity	Mouse	Liver	CN16-E1	1.4e-11
Vars2	GOBP_Amino_Acid_Activation	Mouse	Liver	CN65-C1	4.2e-10
Vars2	GOBP_Ncrna_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-08
Vars2	GOBP_Amide_Biosynthetic_Process	Mouse	Lymph	MS-1	1.3e-09
Vars2	GOBP_Amino_Acid_Activation	Mouse	Lymph	MS-1	1.4e-08
Vars2	GOBP_Aminoacyl_Trna_Metabolism_Involved_In_Translational_Fidelity	Mouse	Lymph	MS-1	1.2e-19
Vars2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-13
Vars2	GOBP_Ncrna_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Vars2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Vars2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Vars2	GOBP_Peptide_Biosynthetic_Process	Mouse	Lymph	MS-1	7.1e-07
Vars2	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Vars2	GOBP_Regulation_Of_Translational_Fidelity	Mouse	Lymph	MS-1	1.9e-11
Vars2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Vars2	GOBP_Trna_Metabolic_Process	Mouse	Lymph	MS-1	1.0e-08
Vars2	GOBP_Amino_Acid_Activation	Mouse	Brain	rep_4	9.9e-142
Vars2	GOBP_Aminoacyl_Trna_Metabolism_Involved_In_Translational_Fidelity	Mouse	Brain	rep_4	1.7e-79
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_4	1.9e-21
Vars2	GOBP_Regulation_Of_Translational_Fidelity	Mouse	Brain	rep_4	1.1e-101
Vars2	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_4	2.6e-107
Vars2	GOBP_Regulation_Of_Translational_Fidelity	Mouse	Brain	HP_ad_rep3	3.2e-08
Vars2	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	8.0e-10
Vars2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Vars2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.0e-14
Vars2	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-10
Vars2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Vars2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Vars2	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	4.4e-10
Vars2	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Vars2	GOBP_Trna_Metabolic_Process	Mouse	Brain	HP_adpolb_rep5	9.9e-10
Vars2	GOBP_Amino_Acid_Activation	Mouse	Brain	HP_polb_rep9	9.7e-14
Vars2	GOBP_Aminoacyl_Trna_Metabolism_Involved_In_Translational_Fidelity	Mouse	Brain	HP_polb_rep9	1.1e-25
Vars2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Vars2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Vars2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Vars2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Vars2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Vars2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source