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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ubr3 (spascer ID:68795)

Gene summary for Ubr3

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ubr3
	Gene ID	68795
	Gene name	ubiquitin protein ligase E3 component n-recognin 3
	Synonyms	1110059H15Rik\|4833421P10Rik\|A130030D10Rik\|AA409735\|AA414972\|AA422631\|AI646861\|AU016126\|Zfp650\|Znf650
	Cytomap	2\|2 C2
	Type of gene	protein-coding
	Description	E3 ubiquitin-protein ligase UBR3N-recognin-3RING-type E3 ubiquitin transferase UBR3ubiquitin-protein ligase E3-alpha-3ubiquitin-protein ligase E3-alpha-IIIzinc finger protein 650
	Modification date	20220424
	UniProtAcc	Q5U430

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ubr3	GO:0000151	ubiquitin ligase complex	21873635	Component
Ubr3	GO:0005737	cytoplasm	21873635	Component
Ubr3	GO:0016567	protein ubiquitination	21873635	Process
Ubr3	GO:0061630	ubiquitin protein ligase activity	21873635	Function
Ubr3	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway	21873635	Process

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Spatial pattern events for Ubr3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ubr3	Mouse	Brain	S1	34413515	2.07e-15
Ubr3	Mouse	Brain	S2	34413515	1.56e-15
Ubr3	Mouse	Brain	S3	34413515	4.37e-10
Ubr3	Mouse	Brain	S4	34413515	3.18e-14
Ubr3	Mouse	Brain	S6	34413515	1.46e-15
Ubr3	Mouse	Brain	S7	34413515	1.07e-12
Ubr3	Mouse	Brain	16A	32637622	2.31e-09
Ubr3	Mouse	Brain	22A	32637622	9.13e-06
Ubr3	Mouse	Brain	rep_1	35141374	2.40e-11
Ubr3	Mouse	Brain	rep_2	35141374	2.69e-06
Ubr3	Mouse	Brain	rep_3	35141374	1.64e-15
Ubr3	Mouse	Brain	rep_4	35141374	1.57e-15
Ubr3	Mouse	Brain	rep_5	35141374	1.47e-15
Ubr3	Mouse	Kidney	IRI	34003797	3.37e-11
Ubr3	Mouse	Brain	rep_1	33469025	1.77e-13
Ubr3	Mouse	Brain	rep_3	35027729	2.05e-10
Ubr3	Mouse	Brain	rep_4	35027729	6.48e-07
Ubr3	Mouse	Brain	rep_5	35027729	2.62e-15
Ubr3	Mouse	Testicle	rep_4	34731600	8.60e-14
Ubr3	Mouse	Brain	rep_1	35210624	3.60e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Kidney_IRI_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Ubr3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ubr3	GOBP_Behavior	Mouse	Spinal cord	L7bCN02_E1	3.7e-06
Ubr3	GOBP_Nervous_System_Process	Mouse	Spinal cord	L7bCN02_E1	2.5e-06
Ubr3	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Ubr3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Ubr3	GOBP_Feeding_Behavior	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Ubr3	GOBP_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Ubr3	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Ubr3	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Ubr3	GOBP_Protein_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Ubr3	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Ubr3	GOBP_Sensory_Perception	Mouse	Spinal cord	L7CN45_C1	5.0e-07
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Spinal cord	L7CN45_C1	3.3e-08
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Spinal cord	L7CN45_C1	9.5e-07
Ubr3	GOBP_Suckling_Behavior	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Ubr3	GOBP_Feeding_Behavior	Mouse	Brain	rep_27	7.5e-05
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Brain	rep_41	3.6e-11
Ubr3	GOBP_Suckling_Behavior	Mouse	Brain	rep_71	5.3e-06
Ubr3	GOBP_Behavior	Mouse	Brain	rep_1	6.8e-65
Ubr3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	rep_1	1.0e-08
Ubr3	GOBP_Nervous_System_Process	Mouse	Brain	rep_1	1.6e-36
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Brain	rep_1	1.5e-17
Ubr3	GOBP_Suckling_Behavior	Mouse	Brain	rep_1	2.7e-29
Ubr3	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	rep_3	2.9e-162
Ubr3	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Ubr3	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	1.7e-159
Ubr3	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	8.7e-167
Ubr3	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Ubr3	GOBP_Proteasomal_Protein_Catabolic_Process	Mouse	Brain	rep_3	2.9e-169
Ubr3	GOBP_Protein_Catabolic_Process	Mouse	Brain	rep_3	3.0e-174
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	rep_3	1.4e-184
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	rep_3	6.3e-190
Ubr3	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Ubr3	GOBP_Sensory_Perception	Mouse	Brain	rep_3	2.9e-57
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Brain	rep_3	4.3e-10
Ubr3	GOBP_Feeding_Behavior	Mouse	Brain	rep_6	2.1e-13
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Embryo	rep_6	9.5e-11
Ubr3	GOBP_Suckling_Behavior	Mouse	Embryo	rep_6	1.3e-31
Ubr3	GOBP_Feeding_Behavior	Mouse	Embryo	rep_14	7.5e-13
Ubr3	GOBP_Sensory_Perception	Mouse	Embryo	rep_14	5.0e-07
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Embryo	rep_14	4.9e-23
Ubr3	GOBP_Behavior	Mouse	Embryo	rep_1	1.7e-148
Ubr3	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Embryo	rep_1	7.5e-10
Ubr3	GOBP_Nervous_System_Process	Mouse	Embryo	rep_1	1.4e-08
Ubr3	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Ubr3	GOBP_Protein_Catabolic_Process	Mouse	Embryo	rep_1	4.1e-19
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Embryo	rep_1	4.4e-16
Ubr3	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Ubr3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Embryo	rep_3	0.0e+00
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Embryo	rep_3	4.2e-21
Ubr3	GOBP_Sensory_Perception	Mouse	Embryo	rep_3	0.0e+00
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Embryo	rep_3	0.0e+00
Ubr3	GOBP_Suckling_Behavior	Mouse	Embryo	rep_5	7.5e-50
Ubr3	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Ubr3	GOBP_Behavior	Mouse	Kidney	rep_2	1.0e-54
Ubr3	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Kidney	rep_2	3.2e-21
Ubr3	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Ubr3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Kidney	rep_2	9.8e-28
Ubr3	GOBP_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	7.0e-40
Ubr3	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	1.0e-26
Ubr3	GOBP_Nervous_System_Process	Mouse	Kidney	rep_2	1.9e-90
Ubr3	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Ubr3	GOBP_Proteasomal_Protein_Catabolic_Process	Mouse	Kidney	rep_2	5.3e-33
Ubr3	GOBP_Protein_Catabolic_Process	Mouse	Kidney	rep_2	7.3e-30
Ubr3	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Ubr3	GOBP_Sensory_Perception	Mouse	Kidney	rep_2	1.4e-94
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Kidney	rep_2	2.1e-70
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Kidney	rep_2	4.4e-38
Ubr3	GOBP_Suckling_Behavior	Mouse	Kidney	rep_2	3.6e-53
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Liver	CN16-D2	2.3e-07
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Liver	CN16-D2	9.5e-07
Ubr3	GOBP_Nervous_System_Process	Mouse	Liver	CN73-C1	1.7e-08
Ubr3	GOBP_Feeding_Behavior	Mouse	Liver	rep_16	5.1e-15
Ubr3	GOBP_Suckling_Behavior	Mouse	Liver	rep_16	9.2e-07
Ubr3	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Ubr3	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Ubr3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Lymph	MS-1	4.0e-11
Ubr3	GOBP_Feeding_Behavior	Mouse	Lymph	MS-1	1.2e-10
Ubr3	GOBP_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Ubr3	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Ubr3	GOBP_Nervous_System_Process	Mouse	Lymph	MS-1	1.4e-08
Ubr3	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Ubr3	GOBP_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Lymph	MS-1	1.4e-09
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Lymph	MS-1	1.4e-09
Ubr3	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Ubr3	GOBP_Sensory_Perception	Mouse	Lymph	MS-1	5.2e-11
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Lymph	MS-1	1.7e-09
Ubr3	GOBP_Suckling_Behavior	Mouse	Lymph	MS-1	1.3e-10
Ubr3	GOBP_Feeding_Behavior	Mouse	Lung	rep_1	1.3e-07
Ubr3	GOBP_Macromolecule_Catabolic_Process	Mouse	Lung	rep_1	2.0e-21
Ubr3	GOBP_Suckling_Behavior	Mouse	Lung	rep_1	4.2e-07
Ubr3	GOBP_Behavior	Mouse	Brain	rep_4	8.1e-10
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Brain	rep_4	8.2e-10
Ubr3	GOBP_Sensory_Perception_Of_Smell	Mouse	Brain	HP_ad_rep3	4.7e-13
Ubr3	GOBP_Behavior	Mouse	Brain	HP_ad_rep7	1.4e-12
Ubr3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	HP_ad_rep7	7.5e-07
Ubr3	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-09
Ubr3	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-08
Ubr3	GOBP_Nervous_System_Process	Mouse	Brain	HP_ad_rep7	7.0e-10
Ubr3	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Ubr3	GOBP_Protein_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	HP_ad_rep7	1.7e-09
Ubr3	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	HP_ad_rep7	6.9e-09
Ubr3	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Ubr3	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	HP_adpolb_rep1	7.2e-07
Ubr3	GOBP_Feeding_Behavior	Mouse	Brain	HP_adpolb_rep1	1.1e-15
Ubr3	GOBP_Proteasomal_Protein_Catabolic_Process	Mouse	Brain	HP_adpolb_rep1	1.1e-07
Ubr3	GOBP_Sensory_Perception_Of_Chemical_Stimulus	Mouse	Brain	HP_adpolb_rep1	1.2e-09
Ubr3	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Ubr3	GOBP_Sensory_Perception	Mouse	Brain	HP_polb_rep9	1.2e-09
Ubr3	GOBP_Suckling_Behavior	Mouse	Brain	HP_polb_rep9	4.0e-11

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Ubr3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ubr3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ubr3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ubr3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ubr3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source