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Spatial pattern gene: Flnc (spascer ID:68794) |
Gene summary for Flnc |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Flnc | Gene ID | 68794 |
| Gene name | filamin C, gamma |
| Synonyms | 1110055E19Rik|ABP-280|ABPL|Fln2 |
| Cytomap | 6 A3.3|6 12.36 cM |
| Type of gene | protein-coding |
| Description | filamin-CABP-280-like proteinactin-binding protein 280actin-binding-like proteinfilamin-2 |
| Modification date | 20220424 |
| UniProtAcc | Q8VHX6 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
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Spatial pattern events for Flnc |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Flnc | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Flnc | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Flnc | Mouse | Embryo | 3D | 34210887 | 1.17e-06 |
| Flnc | Mouse | Embryo | 3F | 34210887 | 2.00e-14 |
| Flnc | Mouse | Embryo | 3G | 34210887 | 1.05e-06 |
| Flnc | Mouse | Embryo | 4A | 34210887 | 7.25e-10 |
| Flnc | Mouse | Embryo | 4C | 34210887 | 7.39e-08 |
| Flnc | Mouse | Embryo | 4D | 34210887 | 2.46e-14 |
| Flnc | Mouse | Embryo | 4E | 34210887 | 1.44e-14 |
| Flnc | Mouse | Embryo | rep_1 | 33188776 | 9.94e-15 |
| Flnc | Mouse | Embryo | rep_2 | 33188776 | 3.59e-10 |
| Flnc | Mouse | Embryo | rep_3 | 33188776 | 1.13e-14 |
| Flnc | Mouse | Embryo | rep_4 | 33188776 | 1.53e-14 |
| Flnc | Mouse | Embryo | rep_5 | 33188776 | 1.25e-10 |
| Flnc | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Flnc | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Flnc | Mouse | Embryo | rep_15 | 33188776 | 5.97e-15 |
| Flnc | Mouse | Kidney | IRI | 34003797 | 3.92e-15 |
| Flnc | Mouse | Kidney | rep_4 | 34853151 | 6.82e-15 |
| Flnc | Mouse | Kidney | rep_5 | 34853151 | 3.18e-15 |
| Flnc | Mouse | Intestine | rep_1 | 35149721 | 1.03e-14 |
| Flnc | Mouse | Intestine | rep_2 | 35149721 | 3.44e-15 |
| Flnc | Mouse | Intestine | rep_3 | 35149721 | 3.25e-15 |
| Flnc | Mouse | Intestine | rep_4 | 35149721 | 2.30e-15 |
| Flnc | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Flnc | Mouse | Lymph | B1 | 0 | 1.11e-14 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_rep_4_H&E  |  |
Kidney_rep_5_H&E  |  |
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Spatial pattern pathway has Flnc envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Spinal cord | CN94_E1 | 9.1e-06 |
| Flnc | GOBP_Muscle_Structure_Development | Mouse | Spinal cord | CN94_E1 | 7.5e-07 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Spinal cord | L7bCN02_E1 | 4.0e-06 |
| Flnc | GOBP_Muscle_Cell_Differentiation | Mouse | Spinal cord | L7CN45_C1 | 5.6e-06 |
| Flnc | GOBP_Striated_Muscle_Cell_Development | Mouse | Spinal cord | L7CN45_C1 | 8.9e-07 |
| Flnc | GOBP_Striated_Muscle_Cell_Differentiation | Mouse | Spinal cord | L7CN45_C1 | 4.2e-06 |
| Flnc | GOBP_Muscle_Cell_Development | Mouse | Spinal cord | L7CN47_C1 | 5.4e-06 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Brain | rep_27 | 5.8e-05 |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Brain | rep_1 | 1.2e-14 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Brain | rep_1 | 1.5e-30 |
| Flnc | GOBP_Muscle_Cell_Development | Mouse | Brain | rep_1 | 4.8e-19 |
| Flnc | GOBP_Muscle_Cell_Differentiation | Mouse | Brain | rep_1 | 2.6e-13 |
| Flnc | GOBP_Striated_Muscle_Cell_Differentiation | Mouse | Brain | rep_1 | 3.6e-08 |
| Flnc | GOBP_Muscle_Structure_Development | Mouse | Brain | rep_3 | 3.3e-77 |
| Flnc | GOBP_Striated_Muscle_Cell_Development | Mouse | Brain | rep_3 | 5.9e-90 |
| Flnc | GOBP_Muscle_Cell_Differentiation | Mouse | Embryo | rep_6 | 1.6e-07 |
| Flnc | GOBP_Striated_Muscle_Cell_Differentiation | Mouse | Embryo | rep_6 | 7.7e-08 |
| Flnc | GOBP_Muscle_Cell_Development | Mouse | Embryo | rep_14 | 9.1e-11 |
| Flnc | GOBP_Striated_Muscle_Cell_Development | Mouse | Embryo | rep_14 | 4.4e-15 |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Embryo | rep_3 | 4.6e-28 |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Kidney | rep_2 | 5.4e-41 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Kidney | rep_2 | 6.2e-52 |
| Flnc | GOBP_Muscle_Cell_Development | Mouse | Kidney | rep_2 | 1.8e-96 |
| Flnc | GOBP_Muscle_Cell_Differentiation | Mouse | Kidney | rep_2 | 4.1e-93 |
| Flnc | GOBP_Muscle_Structure_Development | Mouse | Kidney | rep_2 | 2.7e-36 |
| Flnc | GOBP_Striated_Muscle_Cell_Development | Mouse | Kidney | rep_2 | 2.0e-57 |
| Flnc | GOBP_Striated_Muscle_Cell_Differentiation | Mouse | Kidney | rep_2 | 1.6e-83 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Liver | rep_16 | 1.6e-07 |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Lymph | MS-1 | 7.9e-08 |
| Flnc | GOBP_Muscle_Cell_Development | Mouse | Lymph | MS-1 | 6.4e-10 |
| Flnc | GOBP_Muscle_Cell_Differentiation | Mouse | Lymph | MS-1 | 1.8e-07 |
| Flnc | GOBP_Muscle_Structure_Development | Mouse | Lymph | MS-1 | 3.8e-09 |
| Flnc | GOBP_Striated_Muscle_Cell_Development | Mouse | Lymph | MS-1 | 4.6e-07 |
| Flnc | GOBP_Striated_Muscle_Cell_Differentiation | Mouse | Lymph | MS-1 | 3.3e-09 |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Brain | rep_4 | 6.5e-07 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Brain | rep_4 | 3.7e-07 |
| Flnc | GOBP_Cell_Junction_Assembly | Mouse | Brain | HP_ad_rep7 | 1.3e-11 |
| Flnc | GOBP_Cell_Junction_Organization | Mouse | Brain | HP_ad_rep7 | 2.9e-10 |
| Flnc | GOBP_Muscle_Cell_Differentiation | Mouse | Brain | HP_ad_rep7 | 5.5e-07 |
| Flnc | GOBP_Striated_Muscle_Cell_Differentiation | Mouse | Brain | HP_ad_rep7 | 4.5e-07 |
| Flnc | GOBP_Striated_Muscle_Cell_Development | Mouse | Brain | HP_adpolb_rep1 | 1.3e-07 |
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Flnc function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Flnc function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Flnc envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Flnc |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Flnc |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
