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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Smarcc2 (spascer ID:68094)

Gene summary for Smarcc2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Smarcc2
	Gene ID	68094
	Gene name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
	Synonyms	5930405J04Rik
	Cytomap	10\|10 D3
	Type of gene	protein-coding
	Description	SWI/SNF complex subunit SMARCC2BAF170BRG1-associated factor 170SWI/SNF complex 170 kDa subunitSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2
	Modification date	20220424
	UniProtAcc	Q6PDG5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Smarcc2	GO:0016514	SWI/SNF complex	21873635	Component
Smarcc2	GO:0042393	histone binding	21873635	Function
Smarcc2	GO:0045893	positive regulation of transcription, DNA-templated	21873635	Process
Smarcc2	GO:0071564	npBAF complex	21873635	Component
Smarcc2	GO:0071565	nBAF complex	21873635	Component

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Spatial pattern events for Smarcc2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Smarcc2	Mouse	Brain	S2	34413515	2.85e-15
Smarcc2	Mouse	Brain	S3	34413515	5.72e-15
Smarcc2	Mouse	Brain	S4	34413515	2.43e-15
Smarcc2	Mouse	Brain	S7	34413515	5.94e-07
Smarcc2	Mouse	Brain	08A	32637622	2.06e-06
Smarcc2	Mouse	Brain	rep_1	35141374	2.90e-06
Smarcc2	Mouse	Brain	rep_2	35141374	1.18e-08
Smarcc2	Mouse	Brain	rep_3	35141374	6.86e-12
Smarcc2	Mouse	Brain	rep_4	35141374	5.42e-15
Smarcc2	Mouse	Brain	rep_5	35141374	2.02e-14
Smarcc2	Mouse	Brain	rep_6	35141374	5.96e-15
Smarcc2	Mouse	Embryo	1E	34210887	2.29e-07
Smarcc2	Mouse	Embryo	1F	34210887	8.26e-10
Smarcc2	Mouse	Embryo	3F	34210887	4.30e-09
Smarcc2	Mouse	Embryo	3H	34210887	7.72e-06
Smarcc2	Mouse	Embryo	4D	34210887	1.36e-14
Smarcc2	Mouse	Embryo	4E	34210887	4.53e-15
Smarcc2	Mouse	Embryo	rep_4	33188776	2.34e-10
Smarcc2	Mouse	Brain	rep_1	33469025	2.37e-15
Smarcc2	Mouse	Brain	rep_1	35027729	3.26e-10
Smarcc2	Mouse	Brain	rep_2	35027729	1.57e-15
Smarcc2	Mouse	Brain	rep_3	35027729	1.32e-15
Smarcc2	Mouse	Brain	rep_5	35027729	1.02e-13
Smarcc2	Mouse	Lymph	A1	0	2.68e-07
Smarcc2	Mouse	Lung	rep_4	35290801	2.98e-08
Smarcc2	Mouse	Brain	rep_4	35210624	1.24e-09
Smarcc2	Mouse	Brain	rep_5	35210624	4.82e-13
Smarcc2	Mouse	Brain	rep_6	35210624	9.37e-08
Smarcc2	Mouse	Brain	rep_7	35210624	6.18e-12

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Smarcc2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Spinal cord	CN94_E1	1.9e-06
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	6.2e-07
Smarcc2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Spinal cord	CN94_E1	5.8e-06
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Spinal cord	CN94_E1	4.2e-07
Smarcc2	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Spinal cord	L7bCN02_E1	3.4e-06
Smarcc2	GOBP_Cellular_Component_Disassembly	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Smarcc2	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Smarcc2	GOBP_Chromatin_Organization	Mouse	Spinal cord	L7CN45_C1	3.5e-07
Smarcc2	GOBP_Chromatin_Remodeling	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Smarcc2	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Smarcc2	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	rep_19	1.5e-05
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Brain	rep_19	1.2e-06
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Smarcc2	GOBP_Cellular_Component_Disassembly	Mouse	Brain	rep_1	1.5e-15
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Brain	rep_1	1.1e-08
Smarcc2	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Smarcc2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Smarcc2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Brain	rep_1	4.1e-29
Smarcc2	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	rep_3	1.7e-35
Smarcc2	GOBP_Chromatin_Organization	Mouse	Brain	rep_3	5.1e-215
Smarcc2	GOBP_Chromatin_Remodeling	Mouse	Brain	rep_3	4.4e-194
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	9.4e-206
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Brain	rep_3	1.5e-62
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Brain	rep_3	1.4e-131
Smarcc2	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Brain	rep_3	5.3e-122
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Embryo	rep_14	7.8e-13
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Embryo	rep_14	1.7e-10
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Embryo	rep_14	1.2e-31
Smarcc2	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Embryo	rep_14	2.2e-11
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Smarcc2	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Embryo	rep_3	4.5e-65
Smarcc2	GOBP_Chromatin_Organization	Mouse	Embryo	rep_3	2.9e-87
Smarcc2	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	1.5e-267
Smarcc2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Smarcc2	GOBP_Cellular_Component_Disassembly	Mouse	Kidney	rep_2	4.2e-70
Smarcc2	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Kidney	rep_2	1.1e-38
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Kidney	rep_2	2.2e-34
Smarcc2	GOBP_Chromatin_Organization	Mouse	Kidney	rep_2	3.0e-63
Smarcc2	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	7.7e-30
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Kidney	rep_2	4.7e-25
Smarcc2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Smarcc2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Kidney	rep_2	1.4e-54
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Kidney	rep_2	1.6e-30
Smarcc2	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Kidney	rep_2	1.1e-35
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Liver	CN16-D1	9.0e-08
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Liver	CN65-C1	1.6e-09
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Liver	rep_15	8.9e-26
Smarcc2	GOBP_Cellular_Component_Disassembly	Mouse	Lymph	MS-1	2.4e-16
Smarcc2	GOBP_Chromatin_Organization	Mouse	Lymph	MS-1	9.1e-11
Smarcc2	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	1.8e-10
Smarcc2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Smarcc2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Lymph	MS-1	5.5e-11
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Lymph	MS-1	2.3e-07
Smarcc2	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Lymph	MS-1	2.3e-09
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Lymph	PBS	6.0e-07
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lung	rep_1	5.8e-10
Smarcc2	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	HP_ad_rep7	6.7e-07
Smarcc2	GOBP_Chromatin_Disassembly	Mouse	Brain	HP_ad_rep7	3.1e-08
Smarcc2	GOBP_Chromatin_Organization	Mouse	Brain	HP_ad_rep7	7.6e-11
Smarcc2	GOBP_Chromatin_Remodeling	Mouse	Brain	HP_ad_rep7	5.3e-11
Smarcc2	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Smarcc2	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Smarcc2	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-11
Smarcc2	GOBP_Nucleosome_Organization	Mouse	Brain	HP_ad_rep7	6.7e-07
Smarcc2	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Smarcc2	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Brain	HP_ad_rep7	9.8e-13
Smarcc2	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Brain	HP_adpolb_rep5	3.5e-12
Smarcc2	GOBP_Cellular_Component_Disassembly	Mouse	Brain	HP_polb_rep9	3.4e-08
Smarcc2	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Brain	HP_polb_rep9	1.8e-08

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Smarcc2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Smarcc2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Smarcc2 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
Smarcc2	Lymph	control	Ifit3 high B	Asxl2,Ubap2l,Csde1, etc.	0.261
Smarcc2	Lymph	control	Mature B	Asxl2,Ubap2l,Csde1, etc.	0.339

Motif information.

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Related Drugs for Smarcc2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Smarcc2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Smarcc2	C0265338	Coffin-Siris syndrome	1	ORPHANET
Smarcc2	C0557874	Global developmental delay	1	GENOMICS_ENGLAND
Smarcc2	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND