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Spatial pattern gene: Mpnd (spascer ID:68047) |
Gene summary for Mpnd |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Mpnd | Gene ID | 68047 |
| Gene name | MPN domain containing |
| Synonyms | E130307M08Rik |
| Cytomap | 17|17 D |
| Type of gene | protein-coding |
| Description | MPN domain-containing protein |
| Modification date | 20220424 |
| UniProtAcc | Q3TV65 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Mpnd | GO:0003713 | transcription coactivator activity | 21873635 | Function |
| Mpnd | GO:0006338 | chromatin remodeling | 21873635 | Process |
| Mpnd | GO:0042393 | histone binding | 21873635 | Function |
| Mpnd | GO:0045944 | positive regulation of transcription by RNA polymerase II | 21873635 | Process |
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Spatial pattern events for Mpnd |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Mpnd | Mouse | Brain | S3 | 34413515 | 8.57e-08 |
| Mpnd | Mouse | Brain | S4 | 34413515 | 5.69e-09 |
| Mpnd | Mouse | Brain | rep_6 | 35141374 | 2.34e-12 |
| Mpnd | Mouse | Embryo | 4C | 34210887 | 2.95e-06 |
| Mpnd | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Mpnd | Mouse | Kidney | IRI | 34003797 | 3.92e-15 |
| Mpnd | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Mpnd | Mouse | Kidney | rep_1 | 34853151 | 5.06e-11 |
| Mpnd | Mouse | Kidney | rep_3 | 34853151 | 2.94e-15 |
| Mpnd | Mouse | Kidney | rep_4 | 34853151 | 4.07e-15 |
| Mpnd | Mouse | Kidney | rep_5 | 34853151 | 1.02e-14 |
| Mpnd | Mouse | Brain | rep_1 | 33469025 | 1.34e-06 |
| Mpnd | Mouse | Brain | rep_2 | 35027729 | 2.50e-08 |
| Mpnd | Mouse | Brain | rep_3 | 35027729 | 3.78e-10 |
| Mpnd | Mouse | Brain | rep_5 | 35027729 | 2.26e-10 |
| Mpnd | Mouse | Intestine | rep_4 | 35149721 | 2.30e-15 |
| Mpnd | Mouse | Brain | rep_1 | 35210624 | 6.32e-10 |
| Mpnd | Mouse | Brain | rep_2 | 35210624 | 5.91e-06 |
| Mpnd | Mouse | Brain | rep_3 | 35210624 | 4.81e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_4_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Mpnd envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Mpnd | GOBP_Chromatin_Organization | Mouse | Spinal cord | L7CN45_C1 | 3.5e-07 |
| Mpnd | GOBP_Chromatin_Remodeling | Mouse | Spinal cord | L7CN45_C1 | 4.5e-06 |
| Mpnd | GOBP_Chromosome_Organization | Mouse | Spinal cord | L7CN45_C1 | 3.4e-08 |
| Mpnd | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Mpnd | GOBP_Proteolysis | Mouse | Spinal cord | L7CN45_C1 | 1.1e-06 |
| Mpnd | GOBP_Chromosome_Organization | Mouse | Brain | rep_1 | 3.9e-07 |
| Mpnd | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | rep_1 | 2.5e-12 |
| Mpnd | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | rep_1 | 1.6e-17 |
| Mpnd | GOBP_Chromatin_Organization | Mouse | Brain | rep_3 | 5.1e-215 |
| Mpnd | GOBP_Chromatin_Remodeling | Mouse | Brain | rep_3 | 4.4e-194 |
| Mpnd | GOBP_Proteolysis | Mouse | Brain | rep_3 | 1.8e-168 |
| Mpnd | GOBP_Chromatin_Organization | Mouse | Embryo | rep_3 | 2.9e-87 |
| Mpnd | GOBP_Chromosome_Organization | Mouse | Embryo | rep_3 | 1.4e-57 |
| Mpnd | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Embryo | rep_3 | 0.0e+00 |
| Mpnd | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Embryo | rep_3 | 0.0e+00 |
| Mpnd | GOBP_Proteolysis | Mouse | Kidney | Nep | 6.8e-23 |
| Mpnd | GOBP_Chromatin_Organization | Mouse | Kidney | rep_2 | 3.0e-63 |
| Mpnd | GOBP_Chromosome_Organization | Mouse | Kidney | rep_2 | 1.0e-14 |
| Mpnd | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Kidney | rep_2 | 4.5e-10 |
| Mpnd | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Kidney | rep_2 | 8.3e-40 |
| Mpnd | GOBP_Proteolysis | Mouse | Kidney | rep_2 | 6.0e-106 |
| Mpnd | GOBP_Chromatin_Organization | Mouse | Lymph | MS-1 | 9.1e-11 |
| Mpnd | GOBP_Chromosome_Organization | Mouse | Lymph | MS-1 | 3.5e-09 |
| Mpnd | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Lymph | MS-1 | 4.4e-12 |
| Mpnd | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Lymph | MS-1 | 1.7e-12 |
| Mpnd | GOBP_Proteolysis | Mouse | Lymph | MS-1 | 2.8e-10 |
| Mpnd | GOBP_Chromatin_Organization | Mouse | Brain | HP_ad_rep7 | 7.6e-11 |
| Mpnd | GOBP_Chromatin_Remodeling | Mouse | Brain | HP_ad_rep7 | 5.3e-11 |
| Mpnd | GOBP_Chromosome_Organization | Mouse | Brain | HP_ad_rep7 | 2.9e-10 |
| Mpnd | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-11 |
| Mpnd | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | HP_ad_rep7 | 7.3e-11 |
| Mpnd | GOBP_Proteolysis | Mouse | Brain | HP_ad_rep7 | 3.3e-07 |
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Mpnd function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Mpnd function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Mpnd envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Mpnd |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Mpnd |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
