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Spatial pattern gene: Cog6 (spascer ID:67542) |
Gene summary for Cog6 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Cog6 | Gene ID | 67542 |
| Gene name | component of oligomeric golgi complex 6 |
| Synonyms | 4933405E16Rik|AU018618|mKIAA1134 |
| Cytomap | 3|3 C |
| Type of gene | protein-coding |
| Description | conserved oligomeric Golgi complex subunit 6COG complex subunit 6conserved oligomeric Golgi complex protein 6 |
| Modification date | 20220424 |
| UniProtAcc | Q8R3I3 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Cog6 | GO:0006891 | intra-Golgi vesicle-mediated transport | 21873635 | Process |
| Cog6 | GO:0017119 | Golgi transport complex | 21873635 | Component |
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Spatial pattern events for Cog6 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Cog6 | Mouse | Brain | S4 | 34413515 | 4.65e-15 |
| Cog6 | Mouse | Brain | rep_4 | 35141374 | 5.37e-06 |
| Cog6 | Mouse | Kidney | IRI | 34003797 | 1.89e-07 |
| Cog6 | Mouse | Brain | rep_1 | 33469025 | 3.36e-08 |
| Cog6 | Mouse | Intestine | rep_3 | 35149721 | 5.21e-15 |
| Cog6 | Mouse | Intestine | rep_4 | 35149721 | 3.90e-15 |
| Cog6 | Mouse | Testicle | rep_4 | 34731600 | 1.79e-11 |
| Cog6 | Mouse | Lymph | B1 | 0 | 7.27e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_4_H&E  |  |
Kidney_IRI_H&E  |  |
Brain_rep_1_H&E  |
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Spatial pattern pathway has Cog6 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Cog6 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Spinal cord | L7CN45_C1 | 7.4e-08 |
| Cog6 | GOBP_Establishment_Of_Protein_Localization | Mouse | Spinal cord | L7CN45_C1 | 4.4e-06 |
| Cog6 | GOBP_Glycosylation | Mouse | Spinal cord | L7CN45_C1 | 8.2e-08 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Spinal cord | L7CN45_C1 | 3.6e-07 |
| Cog6 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Mouse | Spinal cord | L7CN45_C1 | 5.5e-08 |
| Cog6 | GOBP_Intracellular_Transport | Mouse | Spinal cord | L7CN45_C1 | 4.4e-06 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Brain | rep_27 | 5.1e-06 |
| Cog6 | GOBP_Establishment_Of_Protein_Localization | Mouse | Brain | rep_1 | 6.6e-07 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Brain | rep_1 | 1.2e-15 |
| Cog6 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Mouse | Brain | rep_1 | 8.8e-43 |
| Cog6 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Brain | rep_3 | 7.6e-183 |
| Cog6 | GOBP_Glycosylation | Mouse | Brain | rep_3 | 1.2e-150 |
| Cog6 | GOBP_Intracellular_Transport | Mouse | Brain | rep_3 | 1.0e-102 |
| Cog6 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Mouse | Embryo | rep_6 | 7.3e-16 |
| Cog6 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Embryo | rep_14 | 4.4e-33 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Embryo | rep_14 | 5.7e-09 |
| Cog6 | GOBP_Glycosylation | Mouse | Embryo | rep_3 | 2.6e-64 |
| Cog6 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Kidney | rep_2 | 1.8e-93 |
| Cog6 | GOBP_Establishment_Of_Protein_Localization | Mouse | Kidney | rep_2 | 9.8e-86 |
| Cog6 | GOBP_Glycosylation | Mouse | Kidney | rep_2 | 5.3e-81 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Kidney | rep_2 | 6.5e-131 |
| Cog6 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Mouse | Kidney | rep_2 | 4.5e-98 |
| Cog6 | GOBP_Intracellular_Transport | Mouse | Kidney | rep_2 | 7.9e-80 |
| Cog6 | GOBP_Glycosylation | Mouse | Liver | CN73-C1 | 2.0e-07 |
| Cog6 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Lymph | MS-1 | 4.3e-11 |
| Cog6 | GOBP_Establishment_Of_Protein_Localization | Mouse | Lymph | MS-1 | 2.5e-11 |
| Cog6 | GOBP_Glycosylation | Mouse | Lymph | MS-1 | 4.8e-08 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Lymph | MS-1 | 5.2e-08 |
| Cog6 | GOBP_Intracellular_Transport | Mouse | Lymph | MS-1 | 3.3e-11 |
| Cog6 | GOBP_Intra_Golgi_Vesicle_Mediated_Transport | Mouse | Brain | rep_4 | 3.0e-32 |
| Cog6 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Brain | HP_ad_rep7 | 6.3e-08 |
| Cog6 | GOBP_Establishment_Of_Protein_Localization | Mouse | Brain | HP_ad_rep7 | 8.7e-10 |
| Cog6 | GOBP_Glycosylation | Mouse | Brain | HP_ad_rep7 | 3.3e-08 |
| Cog6 | GOBP_Golgi_Vesicle_Transport | Mouse | Brain | HP_ad_rep7 | 1.1e-09 |
| Cog6 | GOBP_Intracellular_Transport | Mouse | Brain | HP_ad_rep7 | 3.1e-08 |
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Cog6 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Cog6 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Cog6 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Cog6 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Cog6 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Cog6 | C3553230 | CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl | 6 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Cog6 | C3809160 | Hypohidrosis, enamel hypoplasia, palmoplantar keratoderma, intellectual disability syndrome | 5 | GENOMICS_ENGLAND;ORPHANET |
