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Spatial pattern gene: Uqcrb (spascer ID:67530) |
Gene summary for Uqcrb |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Uqcrb | Gene ID | 67530 |
| Gene name | ubiquinol-cytochrome c reductase binding protein |
| Synonyms | 2210415M14Rik|QP-C|QPC|UQBC|UQBP|UQPC |
| Cytomap | 13|13 B3 |
| Type of gene | protein-coding |
| Description | cytochrome b-c1 complex subunit 7complex III subunit 7complex III subunit VIIubiquinol-cytochrome c reductase complex 14 kDa protein |
| Modification date | 20220424 |
| UniProtAcc | Q9D855 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Uqcrb | GO:0005750 | mitochondrial respiratory chain complex III | 21873635 | Component |
| Uqcrb | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c | 21873635 | Process |
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Spatial pattern events for Uqcrb |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Uqcrb | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Uqcrb | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Uqcrb | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Uqcrb | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Uqcrb | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Uqcrb | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Uqcrb | Mouse | Brain | 01B | 32637622 | 3.98e-06 |
| Uqcrb | Mouse | Brain | 22B | 32637622 | 9.81e-10 |
| Uqcrb | Mouse | Brain | 28A | 32637622 | 2.36e-08 |
| Uqcrb | Mouse | Brain | 29A | 32637622 | 1.39e-07 |
| Uqcrb | Mouse | Brain | 29B | 32637622 | 2.93e-11 |
| Uqcrb | Mouse | Brain | rep_1 | 35141374 | 3.58e-15 |
| Uqcrb | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Uqcrb | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Uqcrb | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Uqcrb | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Uqcrb | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Uqcrb | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Uqcrb | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Uqcrb | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Uqcrb | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Uqcrb | Mouse | Kidney | rep_2 | 34853151 | 9.38e-09 |
| Uqcrb | Mouse | Kidney | rep_3 | 34853151 | 2.94e-15 |
| Uqcrb | Mouse | Kidney | rep_4 | 34853151 | 3.14e-12 |
| Uqcrb | Mouse | Kidney | rep_5 | 34853151 | 3.18e-15 |
| Uqcrb | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Uqcrb | Mouse | Liver | rep_14 | 35021063 | 2.12e-14 |
| Uqcrb | Mouse | Liver | rep_16 | 35021063 | 7.00e-09 |
| Uqcrb | Mouse | Liver | rep_17 | 35021063 | 2.18e-14 |
| Uqcrb | Mouse | Liver | rep_18 | 35021063 | 6.88e-11 |
| Uqcrb | Mouse | Liver | rep_19 | 35021063 | 3.50e-14 |
| Uqcrb | Mouse | Liver | rep_20 | 35021063 | 4.20e-09 |
| Uqcrb | Mouse | Liver | rep_21 | 35021063 | 7.60e-07 |
| Uqcrb | Mouse | Liver | rep_22 | 35021063 | 3.12e-14 |
| Uqcrb | Mouse | Liver | rep_23 | 35021063 | 2.29e-14 |
| Uqcrb | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Uqcrb | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Uqcrb | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Uqcrb | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Uqcrb | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Uqcrb | Mouse | Intestine | rep_1 | 35149721 | 1.48e-07 |
| Uqcrb | Mouse | Intestine | rep_2 | 35149721 | 3.44e-15 |
| Uqcrb | Mouse | Intestine | rep_3 | 35149721 | 3.25e-15 |
| Uqcrb | Mouse | Intestine | rep_4 | 35149721 | 2.30e-15 |
| Uqcrb | Mouse | Brain | B05_D2 | 32702314 | 1.22e-07 |
| Uqcrb | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Uqcrb | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Uqcrb | Mouse | Lung | rep_1 | 35290801 | 1.21e-14 |
| Uqcrb | Mouse | Lung | rep_2 | 35290801 | 1.25e-08 |
| Uqcrb | Mouse | Lung | rep_3 | 35290801 | 1.16e-11 |
| Uqcrb | Mouse | Lung | rep_4 | 35290801 | 8.36e-06 |
| Uqcrb | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Uqcrb | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Uqcrb | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Uqcrb | Mouse | Brain | rep_5 | 35210624 | 1.42e-13 |
| Uqcrb | Mouse | Brain | rep_6 | 35210624 | 2.05e-15 |
| Uqcrb | Mouse | Brain | rep_7 | 35210624 | 4.41e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_2_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_4_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Liver_rep_14_H&E  | |
Liver_rep_16_H&E  | |
Liver_rep_17_H&E  | |
Liver_rep_18_H&E  | |
Liver_rep_19_H&E  | |
Liver_rep_20_H&E  | |
Liver_rep_21_H&E  | |
Liver_rep_22_H&E  | |
Liver_rep_23_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B05_D2_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
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Spatial pattern pathway has Uqcrb envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Uqcrb | GOBP_Cellular_Respiration | Mouse | Spinal cord | L7CN45_C1 | 7.0e-07 |
| Uqcrb | GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds | Mouse | Spinal cord | L7CN45_C1 | 6.8e-07 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Spinal cord | L7CN45_C1 | 2.2e-08 |
| Uqcrb | GOBP_Oxidative_Phosphorylation | Mouse | Spinal cord | L7CN45_C1 | 5.1e-07 |
| Uqcrb | GOBP_Atp_Metabolic_Process | Mouse | Spinal cord | L7CN47_D1 | 3.0e-06 |
| Uqcrb | GOBP_Aerobic_Respiration | Mouse | Brain | rep_71 | 1.9e-06 |
| Uqcrb | GOBP_Atp_Metabolic_Process | Mouse | Brain | rep_71 | 2.7e-06 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Brain | rep_71 | 1.2e-05 |
| Uqcrb | GOBP_Cellular_Respiration | Mouse | Brain | rep_71 | 1.7e-06 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Brain | rep_71 | 2.4e-06 |
| Uqcrb | GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds | Mouse | Brain | rep_71 | 3.4e-07 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Brain | rep_71 | 2.1e-06 |
| Uqcrb | GOBP_Oxidative_Phosphorylation | Mouse | Brain | rep_71 | 5.5e-06 |
| Uqcrb | GOBP_Respiratory_Electron_Transport_Chain | Mouse | Brain | rep_71 | 1.2e-05 |
| Uqcrb | GOBP_Aerobic_Respiration | Mouse | Brain | rep_1 | 5.5e-37 |
| Uqcrb | GOBP_Atp_Metabolic_Process | Mouse | Brain | rep_1 | 2.0e-14 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Brain | rep_1 | 7.9e-39 |
| Uqcrb | GOBP_Cellular_Respiration | Mouse | Brain | rep_1 | 9.5e-36 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Brain | rep_1 | 1.3e-47 |
| Uqcrb | GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds | Mouse | Brain | rep_1 | 1.1e-29 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Brain | rep_1 | 5.4e-15 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Brain | rep_1 | 5.2e-13 |
| Uqcrb | GOBP_Oxidative_Phosphorylation | Mouse | Brain | rep_1 | 7.5e-43 |
| Uqcrb | GOBP_Respiratory_Electron_Transport_Chain | Mouse | Brain | rep_1 | 4.5e-44 |
| Uqcrb | GOBP_Cellular_Respiration | Mouse | Embryo | rep_6 | 3.9e-08 |
| Uqcrb | GOBP_Aerobic_Respiration | Mouse | Embryo | rep_14 | 4.2e-31 |
| Uqcrb | GOBP_Atp_Metabolic_Process | Mouse | Embryo | rep_14 | 3.7e-37 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Embryo | rep_14 | 3.4e-58 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Embryo | rep_14 | 5.7e-46 |
| Uqcrb | GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds | Mouse | Embryo | rep_14 | 2.3e-31 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Embryo | rep_14 | 2.9e-37 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Embryo | rep_14 | 2.1e-29 |
| Uqcrb | GOBP_Oxidative_Phosphorylation | Mouse | Embryo | rep_14 | 7.0e-41 |
| Uqcrb | GOBP_Respiratory_Electron_Transport_Chain | Mouse | Embryo | rep_14 | 8.9e-41 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Embryo | rep_3 | 3.7e-124 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Kidney | rep_2 | 3.3e-14 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Kidney | rep_2 | 5.1e-50 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Liver | CN65-C1 | 1.6e-09 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Liver | CN65-D1 | 6.0e-12 |
| Uqcrb | GOBP_Aerobic_Respiration | Mouse | Liver | rep_16 | 2.7e-35 |
| Uqcrb | GOBP_Atp_Metabolic_Process | Mouse | Liver | rep_16 | 1.2e-30 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Liver | rep_16 | 4.4e-24 |
| Uqcrb | GOBP_Cellular_Respiration | Mouse | Liver | rep_16 | 8.0e-25 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Liver | rep_16 | 1.7e-16 |
| Uqcrb | GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds | Mouse | Liver | rep_16 | 2.0e-28 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Liver | rep_16 | 7.4e-11 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Liver | rep_16 | 1.9e-44 |
| Uqcrb | GOBP_Oxidative_Phosphorylation | Mouse | Liver | rep_16 | 1.4e-27 |
| Uqcrb | GOBP_Respiratory_Electron_Transport_Chain | Mouse | Liver | rep_16 | 2.4e-29 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Intestine | rep_2 | 3.8e-16 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Intestine | rep_2 | 8.8e-09 |
| Uqcrb | GOBP_Respiratory_Electron_Transport_Chain | Mouse | Intestine | rep_2 | 2.9e-16 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Lymph | MS-2 | 8.2e-07 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Lymph | MS-2 | 2.2e-07 |
| Uqcrb | GOBP_Aerobic_Respiration | Mouse | Brain | HP_polb_rep9 | 1.4e-09 |
| Uqcrb | GOBP_Atp_Metabolic_Process | Mouse | Brain | HP_polb_rep9 | 1.0e-11 |
| Uqcrb | GOBP_Atp_Synthesis_Coupled_Electron_Transport | Mouse | Brain | HP_polb_rep9 | 4.5e-08 |
| Uqcrb | GOBP_Cellular_Respiration | Mouse | Brain | HP_polb_rep9 | 2.1e-07 |
| Uqcrb | GOBP_Electron_Transport_Chain | Mouse | Brain | HP_polb_rep9 | 5.9e-10 |
| Uqcrb | GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds | Mouse | Brain | HP_polb_rep9 | 3.0e-10 |
| Uqcrb | GOBP_Generation_Of_Precursor_Metabolites_And_Energy | Mouse | Brain | HP_polb_rep9 | 5.4e-11 |
| Uqcrb | GOBP_Mitochondrial_Electron_Transport_Ubiquinol_To_Cytochrome_C | Mouse | Brain | HP_polb_rep9 | 2.4e-09 |
| Uqcrb | GOBP_Oxidative_Phosphorylation | Mouse | Brain | HP_polb_rep9 | 9.8e-11 |
| Uqcrb | GOBP_Respiratory_Electron_Transport_Chain | Mouse | Brain | HP_polb_rep9 | 1.8e-08 |
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Uqcrb function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Uqcrb function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication | ||
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Transcription factor for Uqcrb envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| UQCRB | Skin | tumor | T_cells | RPL34,RPL41,RPS27, etc. | 0.375 |
| UQCRB | Skin | tumor | Neurons | RPL34,RPL41,RPS27, etc. | 0.517 |
| UQCRB | Skin | tumor | Tissue_stem_cells | RPL34,RPL41,RPS27, etc. | 0.259 |
| Uqcrb | Lymph | control | Ifit3 high B | Cycs,Nedd8,Psmb5, etc. | 0.253 |
| Uqcrb | Lymph | control | Mature B | Cycs,Nedd8,Psmb5, etc. | 0.364 |
| Uqcrb | Lymph | control | CD8 T | Cycs,Nedd8,Psmb5, etc. | 0.252 |
| Uqcrb | Liver | SD_36week | Endothelial | Ppia,Cox4i1,Cox7b, etc. | 0.435 |
| Uqcrb | Liver | SD_36week | Hepatocyte | Ppia,Cox4i1,Cox7b, etc. | 0.33 |
| Uqcrb | Liver | SD_36week | KC | Ppia,Cox4i1,Cox7b, etc. | 0.289 |
| Uqcrb | Liver | SD_36week | Monocyte | Ppia,Cox4i1,Cox7b, etc. | 0.251 |
| Uqcrb | Lymph | disease | CD8 T | Cox8a,Chchd2,Ppp1r11, etc. | 0.258 |
| Uqcrb | Lymph | disease | Ifit3 high B | Cox8a,Chchd2,Ppp1r11, etc. | 0.308 |
| Uqcrb | Lymph | disease | CD4 T | Cox8a,Chchd2,Ppp1r11, etc. | 0.259 |
| Uqcrb | Lymph | disease | Mature B | Cox8a,Chchd2,Ppp1r11, etc. | 0.35 |
| Motif information. |
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Related Drugs for Uqcrb |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Uqcrb |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Uqcrb | C3554606 | MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 3 | 4 | GENOMICS_ENGLAND |
| Uqcrb | C0751651 | Mitochondrial Diseases | 1 | GENOMICS_ENGLAND |
