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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Atg12 (spascer ID:67526)

Gene summary for Atg12

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Atg12
	Gene ID	67526
	Gene name	autophagy related 12
	Synonyms	4931423H11Rik\|A330058M13Rik\|Apg12l\|Atg12l
	Cytomap	18\|18 C
	Type of gene	protein-coding
	Description	ubiquitin-like protein ATG12autophagy-related protein 12
	Modification date	20220424
	UniProtAcc	Q9CQY1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Atg12	GO:0000045	autophagosome assembly	21873635	Process
Atg12	GO:0000422	autophagy of mitochondrion	21873635	Process
Atg12	GO:0006501	C-terminal protein lipidation	21873635	Process
Atg12	GO:0034045	phagophore assembly site membrane	21873635	Component
Atg12	GO:0034274	Atg12-Atg5-Atg16 complex	21873635	Component
Atg12	GO:0044804	autophagy of nucleus	21873635	Process

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Spatial pattern events for Atg12

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Atg12	Mouse	Brain	S4	34413515	1.40e-08
Atg12	Mouse	Brain	S6	34413515	2.66e-15
Atg12	Mouse	Brain	rep_4	35141374	1.13e-09
Atg12	Mouse	Embryo	rep_5	33188776	4.36e-09
Atg12	Mouse	Kidney	IRI	34003797	1.39e-10
Atg12	Mouse	Brain	rep_1	33469025	1.30e-15
Atg12	Mouse	Brain	rep_3	35027729	4.22e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Kidney_IRI_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Atg12 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Atg12	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	7.5e-07
Atg12	GOBP_Organelle_Assembly	Mouse	Spinal cord	CN94_E1	9.5e-06
Atg12	GOBP_Autophagosome_Organization	Mouse	Spinal cord	L7bCN02_E1	5.0e-06
Atg12	GOBP_Autophagy_Of_Mitochondrion	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Spinal cord	L7CN45_C1	4.7e-06
Atg12	GOBP_Cellular_Component_Disassembly	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Atg12	GOBP_Lipoprotein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.0e-06
Atg12	GOBP_Macroautophagy	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Atg12	GOBP_Mitochondrion_Organization	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Atg12	GOBP_Organelle_Disassembly	Mouse	Spinal cord	L7CN45_C1	5.6e-07
Atg12	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Spinal cord	L7CN45_C1	5.2e-06
Atg12	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Spinal cord	L7CN47_C1	2.9e-06
Atg12	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	L7CN97_E2	6.8e-06
Atg12	GOBP_Autophagosome_Organization	Mouse	Brain	rep_27	9.0e-05
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Brain	rep_41	9.3e-07
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Brain	rep_1	4.6e-30
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Brain	rep_1	3.0e-50
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Brain	rep_1	1.2e-46
Atg12	GOBP_Cellular_Component_Disassembly	Mouse	Brain	rep_1	1.5e-15
Atg12	GOBP_Macroautophagy	Mouse	Brain	rep_1	6.7e-14
Atg12	GOBP_Autophagosome_Organization	Mouse	Brain	rep_3	5.9e-105
Atg12	GOBP_Autophagy_Of_Mitochondrion	Mouse	Brain	rep_3	2.1e-106
Atg12	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	rep_3	1.9e-146
Atg12	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Brain	rep_3	1.8e-58
Atg12	GOBP_Lipoprotein_Metabolic_Process	Mouse	Brain	rep_3	4.0e-92
Atg12	GOBP_Mitochondrion_Organization	Mouse	Brain	rep_3	1.3e-89
Atg12	GOBP_Organelle_Assembly	Mouse	Brain	rep_3	2.0e-160
Atg12	GOBP_Organelle_Disassembly	Mouse	Brain	rep_3	2.0e-93
Atg12	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Brain	rep_3	6.2e-128
Atg12	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Brain	rep_3	1.0e-145
Atg12	GOBP_Vacuole_Organization	Mouse	Brain	rep_3	9.7e-150
Atg12	GOBP_Autophagy_Of_Mitochondrion	Mouse	Embryo	rep_14	2.1e-07
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Embryo	rep_14	3.5e-69
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Embryo	rep_14	1.2e-54
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Embryo	rep_14	2.2e-29
Atg12	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Embryo	rep_14	9.7e-11
Atg12	GOBP_Mitochondrion_Organization	Mouse	Embryo	rep_14	1.8e-11
Atg12	GOBP_Organelle_Disassembly	Mouse	Embryo	rep_14	2.6e-21
Atg12	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Embryo	rep_14	1.7e-45
Atg12	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_2	7.4e-121
Atg12	GOBP_Mitochondrion_Organization	Mouse	Embryo	rep_3	4.0e-48
Atg12	GOBP_Lipoprotein_Metabolic_Process	Mouse	Embryo	rep_6	6.1e-112
Atg12	GOBP_Organelle_Assembly	Mouse	Embryo	rep_6	4.1e-70
Atg12	GOBP_Autophagosome_Organization	Mouse	Kidney	rep_2	5.0e-88
Atg12	GOBP_Autophagy_Of_Mitochondrion	Mouse	Kidney	rep_2	1.9e-41
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Kidney	rep_2	5.8e-29
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Kidney	rep_2	7.0e-67
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Kidney	rep_2	1.0e-19
Atg12	GOBP_Cellular_Component_Disassembly	Mouse	Kidney	rep_2	4.2e-70
Atg12	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Kidney	rep_2	4.8e-139
Atg12	GOBP_Lipoprotein_Metabolic_Process	Mouse	Kidney	rep_2	1.0e-163
Atg12	GOBP_Macroautophagy	Mouse	Kidney	rep_2	1.3e-64
Atg12	GOBP_Mitochondrion_Organization	Mouse	Kidney	rep_2	1.7e-21
Atg12	GOBP_Organelle_Assembly	Mouse	Kidney	rep_2	2.8e-62
Atg12	GOBP_Organelle_Disassembly	Mouse	Kidney	rep_2	1.2e-56
Atg12	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Kidney	rep_2	7.2e-84
Atg12	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Kidney	rep_2	1.8e-66
Atg12	GOBP_Vacuole_Organization	Mouse	Kidney	rep_2	2.6e-92
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Liver	CN16-D1	5.0e-11
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Liver	CN16-D2	2.0e-09
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Liver	CN65-C1	8.5e-09
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Liver	CN73-C1	9.0e-07
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Liver	rep_15	1.2e-07
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Liver	rep_15	1.0e-16
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Brain	rep_1	3.9e-09
Atg12	GOBP_Autophagosome_Organization	Mouse	Lymph	MS-1	3.1e-11
Atg12	GOBP_Autophagy_Of_Mitochondrion	Mouse	Lymph	MS-1	4.2e-14
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Lymph	MS-1	1.4e-07
Atg12	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	4.6e-18
Atg12	GOBP_Cellular_Component_Disassembly	Mouse	Lymph	MS-1	2.4e-16
Atg12	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Lymph	MS-1	6.0e-07
Atg12	GOBP_Lipoprotein_Metabolic_Process	Mouse	Lymph	MS-1	3.6e-09
Atg12	GOBP_Macroautophagy	Mouse	Lymph	MS-1	3.3e-11
Atg12	GOBP_Mitochondrion_Organization	Mouse	Lymph	MS-1	4.2e-09
Atg12	GOBP_Organelle_Assembly	Mouse	Lymph	MS-1	5.5e-08
Atg12	GOBP_Organelle_Disassembly	Mouse	Lymph	MS-1	5.9e-12
Atg12	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Atg12	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Lymph	MS-1	3.9e-13
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Lymph	PBS	6.0e-07
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Brain	rep_4	9.8e-27
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Brain	rep_4	5.4e-21
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Brain	rep_4	1.7e-27
Atg12	GOBP_Organelle_Disassembly	Mouse	Brain	rep_7	4.5e-11
Atg12	GOBP_Autophagy_Of_Nucleus	Mouse	Brain	HP_ad_rep3	7.5e-08
Atg12	GOBP_C_Terminal_Protein_Lipidation	Mouse	Brain	HP_ad_rep3	1.3e-16
Atg12	GOBP_C_Terminal_Protein_Amino_Acid_Modification	Mouse	Brain	HP_ad_rep7	1.4e-12
Atg12	GOBP_Lipoprotein_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.0e-07
Atg12	GOBP_Macroautophagy	Mouse	Brain	HP_ad_rep7	1.6e-07
Atg12	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Atg12	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Brain	HP_ad_rep7	3.5e-08
Atg12	GOBP_Organelle_Assembly	Mouse	Brain	HP_adpolb_rep1	1.8e-07
Atg12	GOBP_Autophagosome_Organization	Mouse	Brain	HP_polb_rep9	4.0e-09
Atg12	GOBP_Autophagy_Of_Mitochondrion	Mouse	Brain	HP_polb_rep9	3.2e-12
Atg12	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_polb_rep9	1.1e-12
Atg12	GOBP_Cellular_Component_Disassembly	Mouse	Brain	HP_polb_rep9	3.4e-08
Atg12	GOBP_Lipoprotein_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.6e-14
Atg12	GOBP_Mitochondrion_Organization	Mouse	Brain	HP_polb_rep9	1.2e-11
Atg12	GOBP_Organelle_Disassembly	Mouse	Brain	HP_polb_rep9	4.4e-13
Atg12	GOBP_Post_Translational_Protein_Modification	Mouse	Brain	HP_polb_rep9	5.1e-14
Atg12	GOBP_Vacuole_Organization	Mouse	Brain	HP_polb_rep9	9.0e-08

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Atg12 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Atg12 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Atg12 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Atg12

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Atg12

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source