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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Decr1 (spascer ID:67460)

Gene summary for Decr1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Decr1
	Gene ID	67460
	Gene name	2,4-dienoyl CoA reductase 1, mitochondrial
	Synonyms	1200012F07Rik\|Decr\|Nadph
	Cytomap	4\|4 A2
	Type of gene	protein-coding
	Description	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial2,4-dienoyl-CoA reductase, mitochondrial
	Modification date	20220424
	UniProtAcc	Q9CQ62

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Decr1	GO:0005739	mitochondrion	21873635	Component
Decr1	GO:0006635	fatty acid beta-oxidation	21873635	Process
Decr1	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity	21873635	Function

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Spatial pattern events for Decr1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Decr1	Mouse	Brain	S4	34413515	4.65e-15
Decr1	Mouse	Brain	rep_5	35141374	1.68e-11
Decr1	Mouse	Brain	rep_6	35141374	7.68e-06
Decr1	Mouse	Kidney	CLP	34003797	2.19e-15
Decr1	Mouse	Kidney	IRI	34003797	2.29e-15
Decr1	Mouse	Kidney	Sham	34003797	2.58e-15
Decr1	Mouse	Kidney	rep_1	34853151	2.42e-15
Decr1	Mouse	Kidney	rep_2	34853151	5.42e-15
Decr1	Mouse	Kidney	rep_3	34853151	2.94e-15
Decr1	Mouse	Kidney	rep_4	34853151	4.07e-15
Decr1	Mouse	Kidney	rep_5	34853151	3.18e-15
Decr1	Mouse	Brain	rep_1	33469025	1.30e-15
Decr1	Mouse	Liver	rep_21	35021063	8.15e-06
Decr1	Mouse	Brain	rep_2	35027729	6.10e-06
Decr1	Mouse	Brain	rep_3	35027729	4.57e-15
Decr1	Mouse	Intestine	rep_2	35149721	8.00e-08
Decr1	Mouse	Intestine	rep_3	35149721	7.84e-07
Decr1	Mouse	Intestine	rep_4	35149721	5.20e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_21_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Decr1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Spinal cord	CN94_E1	6.4e-06
Decr1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-07
Decr1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	3.7e-06
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Spinal cord	L7bCN02_E1	5.4e-07
Decr1	GOBP_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	8.9e-07
Decr1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Spinal cord	L7CN45_C1	4.5e-09
Decr1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.0e-07
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Decr1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.6e-10
Decr1	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Decr1	GOBP_Lipid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Decr1	GOBP_Lipid_Modification	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Decr1	GOBP_Lipid_Oxidation	Mouse	Spinal cord	L7CN45_C1	8.8e-07
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.2e-09
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Spinal cord	L7CN45_C1	3.5e-09
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Decr1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Decr1	GOBP_Temperature_Homeostasis	Mouse	Spinal cord	L7CN45_C1	8.7e-08
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_11	2.7e-06
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_27	8.3e-05
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	rep_71	3.6e-06
Decr1	GOBP_Lipid_Modification	Mouse	Brain	rep_71	7.0e-06
Decr1	GOBP_Lipid_Oxidation	Mouse	Brain	rep_71	3.6e-06
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_71	8.1e-05
Decr1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Brain	rep_3	3.5e-106
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	rep_3	1.7e-210
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Brain	rep_3	1.3e-180
Decr1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-41
Decr1	GOBP_Lipid_Catabolic_Process	Mouse	Brain	rep_3	1.4e-121
Decr1	GOBP_Lipid_Modification	Mouse	Brain	rep_3	4.5e-101
Decr1	GOBP_Lipid_Oxidation	Mouse	Brain	rep_3	1.2e-128
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_3	2.0e-175
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	3.2e-119
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Brain	rep_3	6.7e-70
Decr1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	rep_3	9.6e-181
Decr1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_3	3.5e-105
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Decr1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Decr1	GOBP_Temperature_Homeostasis	Mouse	Brain	rep_4	9.5e-07
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Brain	rep_7	2.9e-65
Decr1	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Embryo	rep_14	2.8e-18
Decr1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Embryo	rep_14	6.6e-12
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Embryo	rep_14	6.7e-36
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-09
Decr1	GOBP_Lipid_Modification	Mouse	Embryo	rep_14	3.4e-09
Decr1	GOBP_Lipid_Oxidation	Mouse	Embryo	rep_14	9.5e-24
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	7.1e-14
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_14	7.3e-13
Decr1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.3e-13
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Embryo	rep_14	1.4e-13
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Decr1	GOBP_Temperature_Homeostasis	Mouse	Embryo	rep_14	4.5e-07
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Embryo	rep_1	0.0e+00
Decr1	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Decr1	GOBP_Lipid_Metabolic_Process	Mouse	Embryo	rep_1	2.1e-39
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Embryo	rep_1	7.9e-50
Decr1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Decr1	GOBP_Temperature_Homeostasis	Mouse	Embryo	rep_1	0.0e+00
Decr1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Embryo	rep_3	2.1e-07
Decr1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.7e-52
Decr1	GOBP_Lipid_Catabolic_Process	Mouse	Embryo	rep_3	2.1e-07
Decr1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Embryo	rep_3	0.0e+00
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_4	0.0e+00
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Embryo	rep_6	1.5e-08
Decr1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	Nep	1.8e-38
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Kidney	Sham	2.7e-10
Decr1	GOBP_Temperature_Homeostasis	Mouse	Kidney	Sham	7.4e-36
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Kidney	rep_2	2.9e-21
Decr1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Kidney	rep_2	2.5e-44
Decr1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	7.4e-43
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Kidney	rep_2	2.0e-46
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Kidney	rep_2	7.7e-56
Decr1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Kidney	rep_2	2.1e-55
Decr1	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Decr1	GOBP_Lipid_Catabolic_Process	Mouse	Kidney	rep_2	1.4e-56
Decr1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-78
Decr1	GOBP_Lipid_Modification	Mouse	Kidney	rep_2	1.7e-37
Decr1	GOBP_Lipid_Oxidation	Mouse	Kidney	rep_2	2.1e-13
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	2.6e-58
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-73
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Kidney	rep_2	1.3e-51
Decr1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	1.3e-83
Decr1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Kidney	rep_2	3.1e-07
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	rep_2	2.7e-43
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Decr1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Decr1	GOBP_Temperature_Homeostasis	Mouse	Kidney	rep_2	4.5e-41
Decr1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Liver	CN73-C1	9.9e-09
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Liver	CN73-C1	5.5e-08
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Liver	rep_15	7.9e-07
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Liver	rep_16	4.4e-20
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Intestine	rep_2	2.4e-11
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Intestine	rep_2	3.7e-18
Decr1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Intestine	rep_2	3.9e-25
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Intestine	rep_2	1.5e-14
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Lymph	MS-1	1.1e-14
Decr1	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Lymph	MS-1	3.4e-07
Decr1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-14
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Lymph	MS-1	7.8e-09
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Lymph	MS-1	6.3e-09
Decr1	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Lymph	MS-1	8.4e-16
Decr1	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Decr1	GOBP_Lipid_Catabolic_Process	Mouse	Lymph	MS-1	2.6e-07
Decr1	GOBP_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	9.7e-11
Decr1	GOBP_Lipid_Modification	Mouse	Lymph	MS-1	6.5e-09
Decr1	GOBP_Lipid_Oxidation	Mouse	Lymph	MS-1	3.2e-11
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.8e-07
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Lymph	MS-1	1.1e-12
Decr1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.1e-10
Decr1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Lymph	MS-1	4.7e-12
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lymph	MS-1	1.4e-15
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Decr1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Decr1	GOBP_Temperature_Homeostasis	Mouse	Lymph	MS-1	9.0e-11
Decr1	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	4.7e-07
Decr1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-10
Decr1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-13
Decr1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Decr1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	HP_ad_rep7	9.1e-08
Decr1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Decr1	GOBP_Adaptive_Thermogenesis	Mouse	Brain	HP_adpolb_rep1	4.2e-07
Decr1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.9e-07
Decr1	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	HP_polb_rep9	2.3e-12
Decr1	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Decr1	GOBP_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-11
Decr1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-11
Decr1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Brain	HP_polb_rep9	3.2e-07
Decr1	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Brain	HP_polb_rep9	3.4e-10
Decr1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09
Decr1	GOBP_Temperature_Homeostasis	Mouse	Brain	HP_polb_rep9	3.7e-12

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Decr1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Decr1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Decr1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Decr1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Decr1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Decr1	C1857252	2,4-Dienoyl-CoA Reductase Deficiency	2	CTD_human;GENOMICS_ENGLAND
Decr1	C0009171	Cocaine Abuse	1	PSYGENET
Decr1	C0023772	Lipid Metabolism, Inborn Errors	1	CTD_human