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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Xab2 (spascer ID:67439)

Gene summary for Xab2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Xab2
	Gene ID	67439
	Gene name	XPA binding protein 2
	Synonyms	0610041O14Rik\|AV025587
	Cytomap	8 A1.1\|8 1.92 cM
	Type of gene	protein-coding
	Description	pre-mRNA-splicing factor SYF1
	Modification date	20220424
	UniProtAcc	Q9DCD2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Xab2	GO:0000349	generation of catalytic spliceosome for first transesterification step	21873635	Process
Xab2	GO:0000398	mRNA splicing, via spliceosome	21873635	Process
Xab2	GO:0000974	Prp19 complex	21873635	Component
Xab2	GO:0071007	U2-type catalytic step 2 spliceosome	21873635	Component
Xab2	GO:0071014	post-mRNA release spliceosomal complex	21873635	Component

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Spatial pattern events for Xab2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Xab2	Mouse	Kidney	CLP	34003797	4.23e-06
Xab2	Mouse	Kidney	Sham	34003797	2.36e-08
Xab2	Mouse	Kidney	rep_1	34853151	7.51e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E

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Spatial pattern pathway has Xab2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Xab2	GOBP_Cerebral_Cortex_Development	Mouse	Spinal cord	CN93_D2	8.8e-06
Xab2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Xab2	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Spinal cord	L7CN44_D1	2.9e-08
Xab2	GOBP_Blastocyst_Development	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Spinal cord	L7CN45_C1	5.5e-10
Xab2	GOBP_Dna_Repair	Mouse	Spinal cord	L7CN45_C1	9.4e-06
Xab2	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Xab2	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Xab2	GOBP_Forebrain_Development	Mouse	Spinal cord	L7CN45_C1	1.0e-08
Xab2	GOBP_Head_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Xab2	GOBP_Nucleotide_Excision_Repair	Mouse	Spinal cord	L7CN45_C1	1.1e-09
Xab2	GOBP_Pallium_Development	Mouse	Spinal cord	L7CN45_C1	1.2e-06
Xab2	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Xab2	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Xab2	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Xab2	GOBP_Rna_Splicing	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Xab2	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Spinal cord	L7CN45_C1	1.8e-09
Xab2	GOBP_Telencephalon_Development	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Brain	rep_1	8.6e-30
Xab2	GOBP_Cerebral_Cortex_Development	Mouse	Brain	rep_1	8.2e-35
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Brain	rep_1	1.1e-07
Xab2	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	rep_1	1.0e-08
Xab2	GOBP_Forebrain_Development	Mouse	Brain	rep_1	7.3e-42
Xab2	GOBP_Head_Development	Mouse	Brain	rep_1	3.9e-29
Xab2	GOBP_In_Utero_Embryonic_Development	Mouse	Brain	rep_1	1.0e-19
Xab2	GOBP_Pallium_Development	Mouse	Brain	rep_1	2.7e-12
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Brain	rep_1	3.7e-09
Xab2	GOBP_Telencephalon_Development	Mouse	Brain	rep_1	8.6e-69
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Brain	rep_1	5.3e-15
Xab2	GOBP_Blastocyst_Development	Mouse	Brain	rep_3	5.7e-216
Xab2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Xab2	GOBP_Dna_Repair	Mouse	Brain	rep_3	4.0e-216
Xab2	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Xab2	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Xab2	GOBP_Nucleotide_Excision_Repair	Mouse	Brain	rep_3	6.1e-152
Xab2	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	rep_3	5.6e-32
Xab2	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Brain	rep_3	6.1e-80
Xab2	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Xab2	GOBP_Rna_Splicing	Mouse	Brain	rep_3	2.2e-224
Xab2	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	rep_3	1.8e-234
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Embryo	rep_6	1.9e-07
Xab2	GOBP_Blastocyst_Development	Mouse	Embryo	rep_14	5.2e-18
Xab2	GOBP_Nucleotide_Excision_Repair	Mouse	Embryo	rep_14	1.6e-22
Xab2	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Embryo	rep_14	2.1e-33
Xab2	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Embryo	rep_14	6.2e-25
Xab2	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Embryo	rep_14	1.1e-49
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Embryo	rep_1	3.0e-261
Xab2	GOBP_Head_Development	Mouse	Embryo	rep_1	1.8e-91
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Xab2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Embryo	rep_2	7.2e-216
Xab2	GOBP_Dna_Repair	Mouse	Embryo	rep_2	1.6e-282
Xab2	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Xab2	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Xab2	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Embryo	rep_3	0.0e+00
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Kidney	Nep	4.2e-26
Xab2	GOBP_Blastocyst_Development	Mouse	Kidney	rep_2	3.3e-32
Xab2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Kidney	rep_2	1.3e-23
Xab2	GOBP_Cerebral_Cortex_Development	Mouse	Kidney	rep_2	1.2e-22
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-12
Xab2	GOBP_Dna_Repair	Mouse	Kidney	rep_2	5.5e-70
Xab2	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Xab2	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Kidney	rep_2	9.8e-28
Xab2	GOBP_Forebrain_Development	Mouse	Kidney	rep_2	7.6e-21
Xab2	GOBP_Head_Development	Mouse	Kidney	rep_2	1.9e-29
Xab2	GOBP_In_Utero_Embryonic_Development	Mouse	Kidney	rep_2	7.1e-20
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Xab2	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Xab2	GOBP_Nucleotide_Excision_Repair	Mouse	Kidney	rep_2	3.6e-78
Xab2	GOBP_Pallium_Development	Mouse	Kidney	rep_2	2.9e-70
Xab2	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Kidney	rep_2	1.3e-69
Xab2	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Kidney	rep_2	3.3e-25
Xab2	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Xab2	GOBP_Rna_Splicing	Mouse	Kidney	rep_2	1.1e-33
Xab2	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Kidney	rep_2	8.8e-36
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Kidney	rep_2	1.2e-10
Xab2	GOBP_Telencephalon_Development	Mouse	Kidney	rep_2	3.9e-50
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Kidney	rep_2	2.5e-67
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Liver	CN16-D2	2.6e-07
Xab2	GOBP_In_Utero_Embryonic_Development	Mouse	Liver	CN16-D2	6.4e-07
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Xab2	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Xab2	GOBP_Rna_Splicing	Mouse	Liver	CN16-D2	2.4e-07
Xab2	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Liver	CN16-D2	2.0e-09
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Liver	rep_16	8.2e-15
Xab2	GOBP_Head_Development	Mouse	Liver	rep_16	4.3e-18
Xab2	GOBP_In_Utero_Embryonic_Development	Mouse	Liver	rep_16	7.6e-16
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Liver	rep_16	1.2e-37
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Brain	rep_1	2.7e-05
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Brain	rep_1	1.1e-13
Xab2	GOBP_Blastocyst_Development	Mouse	Lymph	MS-1	3.0e-11
Xab2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Lymph	MS-1	3.8e-07
Xab2	GOBP_Cerebral_Cortex_Development	Mouse	Lymph	MS-1	6.9e-10
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Lymph	MS-1	6.8e-10
Xab2	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Xab2	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Lymph	MS-1	4.0e-11
Xab2	GOBP_Forebrain_Development	Mouse	Lymph	MS-1	4.2e-09
Xab2	GOBP_In_Utero_Embryonic_Development	Mouse	Lymph	MS-1	5.3e-13
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Xab2	GOBP_Nucleotide_Excision_Repair	Mouse	Lymph	MS-1	3.7e-09
Xab2	GOBP_Pallium_Development	Mouse	Lymph	MS-1	5.2e-10
Xab2	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Lymph	MS-1	1.7e-07
Xab2	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Xab2	GOBP_Telencephalon_Development	Mouse	Lymph	MS-1	6.8e-10
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Lymph	PBS	7.7e-07
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Brain	rep_4	2.9e-11
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Brain	rep_7	2.2e-16
Xab2	GOBP_Transcription_Coupled_Nucleotide_Excision_Repair	Mouse	Brain	HP_ad_rep2	3.4e-13
Xab2	GOBP_Spliceosomal_Conformational_Changes_To_Generate_Catalytic_Conformation	Mouse	Brain	HP_ad_rep3	1.4e-11
Xab2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Xab2	GOBP_Central_Nervous_System_Development	Mouse	Brain	HP_ad_rep7	2.3e-07
Xab2	GOBP_Cerebral_Cortex_Development	Mouse	Brain	HP_ad_rep7	2.4e-15
Xab2	GOBP_Dna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-11
Xab2	GOBP_Dna_Repair	Mouse	Brain	HP_ad_rep7	2.4e-12
Xab2	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	HP_ad_rep7	7.5e-07
Xab2	GOBP_Forebrain_Development	Mouse	Brain	HP_ad_rep7	5.5e-07
Xab2	GOBP_Head_Development	Mouse	Brain	HP_ad_rep7	3.0e-07
Xab2	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Xab2	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Xab2	GOBP_Nucleotide_Excision_Repair	Mouse	Brain	HP_ad_rep7	4.3e-08
Xab2	GOBP_Pallium_Development	Mouse	Brain	HP_ad_rep7	3.7e-11
Xab2	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	HP_ad_rep7	7.9e-07
Xab2	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Brain	HP_ad_rep7	8.3e-08
Xab2	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Xab2	GOBP_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.3e-10
Xab2	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	HP_ad_rep7	2.3e-11
Xab2	GOBP_Blastocyst_Development	Mouse	Brain	HP_polb_rep9	1.9e-14
Xab2	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Xab2	GOBP_In_Utero_Embryonic_Development	Mouse	Brain	HP_polb_rep9	2.4e-10
Xab2	GOBP_Telencephalon_Development	Mouse	Brain	HP_polb_rep9	1.3e-08

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Xab2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Xab2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Xab2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Xab2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Xab2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source