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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Hoga1 (spascer ID:67432)

Gene summary for Hoga1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Hoga1
	Gene ID	67432
	Gene name	4-hydroxy-2-oxoglutarate aldolase 1
	Synonyms	0610010D20Rik\|Dhdpsl\|Npl2
	Cytomap	19\|19 C3
	Type of gene	protein-coding
	Description	4-hydroxy-2-oxoglutarate aldolase, mitochondrialDHDPS-like proteinN-acetylneuraminate pyruvate lyase 2 (putative)dihydrodipicolinate synthase-like, mitochondrialprobable 2-keto-4-hydroxyglutarate aldolaseprobable KHG-aldolase
	Modification date	20220424
	UniProtAcc	Q9DCU9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Hoga1	GO:0005739	mitochondrion	21873635	Component
Hoga1	GO:0008700	4-hydroxy-2-oxoglutarate aldolase activity	21873635	Function
Hoga1	GO:0009436	glyoxylate catabolic process	21873635	Process

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Spatial pattern events for Hoga1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Hoga1	Mouse	Kidney	CLP	34003797	2.19e-15
Hoga1	Mouse	Kidney	IRI	34003797	2.29e-15
Hoga1	Mouse	Kidney	Sham	34003797	2.58e-15
Hoga1	Mouse	Kidney	rep_1	34853151	2.42e-15
Hoga1	Mouse	Kidney	rep_2	34853151	2.58e-06
Hoga1	Mouse	Kidney	rep_3	34853151	2.94e-15
Hoga1	Mouse	Kidney	rep_4	34853151	4.07e-15
Hoga1	Mouse	Kidney	rep_5	34853151	3.18e-15
Hoga1	Mouse	Liver	rep_20	35021063	7.03e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Liver_rep_20_H&E

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Spatial pattern pathway has Hoga1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Hoga1	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.8e-07
Hoga1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-07
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.5e-07
Hoga1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Hoga1	GOBP_Aldehyde_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.0e-07
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.5e-07
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.2e-09
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.8e-07
Hoga1	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Hoga1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN60_D1	5.3e-06
Hoga1	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN60_D1	5.0e-06
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Brain	rep_11	1.1e-05
Hoga1	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_11	1.9e-05
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_11	2.7e-06
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_71	8.1e-05
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_71	7.6e-05
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Brain	rep_71	1.3e-05
Hoga1	GOBP_Aldehyde_Catabolic_Process	Mouse	Brain	rep_3	1.9e-171
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Brain	rep_3	2.6e-126
Hoga1	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	2.8e-178
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Brain	rep_3	4.2e-133
Hoga1	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Brain	rep_3	1.6e-133
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	8.5e-191
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Mouse	Brain	rep_3	1.1e-35
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.6e-109
Hoga1	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.2e-146
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Brain	rep_3	5.7e-38
Hoga1	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	8.4e-16
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_3	2.0e-175
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	3.2e-119
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	2.0e-17
Hoga1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	rep_3	9.6e-181
Hoga1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Hoga1	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Brain	rep_3	4.4e-42
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Hoga1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Mouse	Embryo	rep_6	6.1e-07
Hoga1	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_6	7.1e-08
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Embryo	rep_6	1.5e-17
Hoga1	GOBP_Aldehyde_Catabolic_Process	Mouse	Embryo	rep_14	1.2e-61
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Embryo	rep_14	1.4e-31
Hoga1	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.5e-20
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Embryo	rep_14	2.9e-38
Hoga1	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.5e-32
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.7e-13
Hoga1	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_14	7.6e-10
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	7.1e-14
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_14	7.3e-13
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_14	7.1e-24
Hoga1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.3e-13
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Embryo	rep_14	3.2e-54
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Hoga1	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Hoga1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Hoga1	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Hoga1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Hoga1	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_4	8.5e-79
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_4	0.0e+00
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_4	1.5e-14
Hoga1	GOBP_Aldehyde_Catabolic_Process	Mouse	Kidney	rep_2	2.1e-132
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Kidney	rep_2	6.9e-48
Hoga1	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-36
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Kidney	rep_2	3.4e-67
Hoga1	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Kidney	rep_2	2.4e-48
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-34
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-36
Hoga1	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	8.2e-31
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Kidney	rep_2	9.1e-115
Hoga1	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	8.2e-57
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	2.6e-58
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-73
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	7.1e-54
Hoga1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	1.3e-83
Hoga1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Hoga1	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Kidney	rep_2	3.6e-95
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Hoga1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Mouse	Liver	CN16-D1	2.7e-10
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Liver	CN16-D1	1.6e-09
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Liver	CN16-D2	1.6e-08
Hoga1	GOBP_Aldehyde_Catabolic_Process	Mouse	Liver	CN16-E1	6.6e-10
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Liver	CN16-E1	5.4e-16
Hoga1	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Liver	CN16-E1	7.0e-07
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Liver	rep_16	8.6e-09
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Intestine	rep_2	1.5e-14
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Intestine	rep_3	2.4e-11
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Lymph	MS-1	7.5e-11
Hoga1	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-13
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-13
Hoga1	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Lymph	MS-1	8.8e-11
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-13
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.7e-15
Hoga1	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	5.2e-18
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.8e-07
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-15
Hoga1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.1e-10
Hoga1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Hoga1	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Lymph	MS-1	7.1e-07
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Hoga1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_4	1.9e-21
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Mouse	Brain	rep_4	2.2e-12
Hoga1	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-13
Hoga1	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.5e-12
Hoga1	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.9e-12
Hoga1	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.0e-14
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	4.8e-15
Hoga1	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	6.2e-09
Hoga1	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-10
Hoga1	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-13
Hoga1	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Hoga1	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Hoga1	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Hoga1	GOBP_Glyoxylate_Metabolic_Process	Mouse	Brain	HP_ad_rep8	1.9e-12
Hoga1	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Brain	HP_adpolb_rep3	5.5e-07
Hoga1	GOBP_Aldehyde_Catabolic_Process	Mouse	Brain	HP_polb_rep9	8.4e-20
Hoga1	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.3e-15
Hoga1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-11
Hoga1	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	3.8e-07
Hoga1	GOBP_Pyruvate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.5e-09
Hoga1	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Hoga1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Hoga1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Hoga1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Hoga1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Hoga1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Hoga1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Hoga1	C3150878	Primary hyperoxaluria type III	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Hoga1	C0008370	Cholestasis	1	CTD_human