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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Coq8a (spascer ID:67426)

Gene summary for Coq8a

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Coq8a
	Gene ID	67426
	Gene name	coenzyme Q8A
	Synonyms	4632432J16Rik\|AI462003\|Adck3\|Cabc1\|mKIAA0451
	Cytomap	1\|1 H4
	Type of gene	protein-coding
	Description	atypical kinase COQ8A, mitochondrialaarF domain containing kinase 3aarF domain-containing protein kinase 3atypical kinase ADCK3, mitochondrialchaperone activity of bc1 complex-like, mitochondrialchaperone, ABC1 activity of bc1 complex likecoenzyme Q
	Modification date	20220424
	UniProtAcc	Q60936

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Coq8a	GO:0006744	ubiquinone biosynthetic process	21873635	Process
Coq8a	GO:0016301	kinase activity	21873635	Function
Coq8a	GO:0031314	extrinsic component of mitochondrial inner membrane	21873635	Component

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Spatial pattern events for Coq8a

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Coq8a	Mouse	Brain	S2	34413515	1.62e-14
Coq8a	Mouse	Brain	S3	34413515	1.64e-15
Coq8a	Mouse	Brain	S4	34413515	3.89e-06
Coq8a	Mouse	Brain	S6	34413515	1.46e-15
Coq8a	Mouse	Brain	S7	34413515	1.55e-15
Coq8a	Mouse	Brain	rep_6	35141374	3.91e-08
Coq8a	Mouse	Kidney	CLP	34003797	2.19e-15
Coq8a	Mouse	Kidney	IRI	34003797	2.29e-15
Coq8a	Mouse	Kidney	Sham	34003797	2.58e-15
Coq8a	Mouse	Kidney	rep_1	34853151	2.42e-15
Coq8a	Mouse	Kidney	rep_2	34853151	6.58e-09
Coq8a	Mouse	Kidney	rep_3	34853151	2.94e-15
Coq8a	Mouse	Kidney	rep_5	34853151	3.18e-15
Coq8a	Mouse	Brain	rep_1	33469025	7.69e-10
Coq8a	Mouse	Liver	rep_20	35021063	9.91e-15
Coq8a	Mouse	Liver	rep_22	35021063	1.22e-13
Coq8a	Mouse	Brain	rep_2	35027729	4.62e-08
Coq8a	Mouse	Brain	rep_3	35027729	9.67e-09
Coq8a	Mouse	Brain	rep_5	35027729	2.46e-06
Coq8a	Mouse	Intestine	rep_4	35149721	5.99e-06
Coq8a	Mouse	Lymph	B1	0	3.72e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_20_H&E
Liver_rep_22_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Coq8a envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.7e-08
Coq8a	GOBP_Quinone_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.2e-07
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Coq8a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Coq8a	GOBP_Ketone_Biosynthetic_Process	Mouse	Brain	rep_42	3.6e-05
Coq8a	GOBP_Ubiquinone_Metabolic_Process	Mouse	Brain	rep_75	4.0e-05
Coq8a	GOBP_Ketone_Biosynthetic_Process	Mouse	Brain	rep_1	1.4e-28
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Brain	rep_3	1.3e-18
Coq8a	GOBP_Quinone_Metabolic_Process	Mouse	Brain	rep_3	1.5e-216
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Coq8a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Coq8a	GOBP_Ubiquinone_Metabolic_Process	Mouse	Brain	rep_3	3.4e-225
Coq8a	GOBP_Ketone_Biosynthetic_Process	Mouse	Embryo	rep_6	9.0e-09
Coq8a	GOBP_Ubiquinone_Metabolic_Process	Mouse	Embryo	rep_6	2.1e-17
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Embryo	rep_14	1.3e-28
Coq8a	GOBP_Quinone_Metabolic_Process	Mouse	Embryo	rep_14	1.2e-60
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Coq8a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Embryo	rep_2	1.2e-11
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-69
Coq8a	GOBP_Quinone_Metabolic_Process	Mouse	Kidney	rep_2	7.3e-114
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Coq8a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Coq8a	GOBP_Ubiquinone_Metabolic_Process	Mouse	Kidney	rep_2	1.0e-31
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-20
Coq8a	GOBP_Ketone_Biosynthetic_Process	Mouse	Lymph	MS-1	3.5e-14
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Coq8a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Coq8a	GOBP_Ubiquinone_Metabolic_Process	Mouse	Lymph	MS-1	5.9e-07
Coq8a	GOBP_Quinone_Metabolic_Process	Mouse	Brain	rep_7	6.8e-26
Coq8a	GOBP_Cellular_Ketone_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.2e-10
Coq8a	GOBP_Ketone_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.0e-14
Coq8a	GOBP_Quinone_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	1.8e-08
Coq8a	GOBP_Ubiquinone_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	5.3e-10
Coq8a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Coq8a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Coq8a function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Coq8a function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Coq8a envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Coq8a

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Coq8a

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source