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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Cap2 (spascer ID:67252)

Gene summary for Cap2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Cap2
	Gene ID	67252
	Gene name	CAP, adenylate cyclase-associated protein, 2 (yeast)
	Synonyms	2810452G09Rik\|AV045235
	Cytomap	13\|13 A5
	Type of gene	protein-coding
	Description	adenylyl cyclase-associated protein 2
	Modification date	20220424
	UniProtAcc	Q9CYT6

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Cap2	GO:0000902	cell morphogenesis	21873635	Process
Cap2	GO:0003779	actin binding	21873635	Function
Cap2	GO:0005737	cytoplasm	21873635	Component
Cap2	GO:0008179	adenylate cyclase binding	21873635	Function
Cap2	GO:0019933	cAMP-mediated signaling	21873635	Process
Cap2	GO:0045761	regulation of adenylate cyclase activity	21873635	Process

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Spatial pattern events for Cap2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Cap2	Mouse	Brain	S1	34413515	2.07e-15
Cap2	Mouse	Brain	S2	34413515	1.56e-15
Cap2	Mouse	Brain	S3	34413515	1.64e-15
Cap2	Mouse	Brain	S4	34413515	1.37e-15
Cap2	Mouse	Brain	S6	34413515	1.46e-15
Cap2	Mouse	Brain	S7	34413515	1.55e-15
Cap2	Mouse	Brain	01B	32637622	2.65e-07
Cap2	Mouse	Brain	12B	32637622	1.42e-13
Cap2	Mouse	Brain	14A	32637622	3.02e-07
Cap2	Mouse	Brain	14B	32637622	3.20e-08
Cap2	Mouse	Brain	17B	32637622	2.97e-06
Cap2	Mouse	Brain	18A	32637622	5.30e-08
Cap2	Mouse	Brain	19A	32637622	7.09e-09
Cap2	Mouse	Brain	19B	32637622	6.44e-08
Cap2	Mouse	Brain	21A	32637622	4.37e-10
Cap2	Mouse	Brain	22A	32637622	1.97e-13
Cap2	Mouse	Brain	22B	32637622	8.81e-15
Cap2	Mouse	Brain	23A	32637622	5.16e-07
Cap2	Mouse	Brain	23B	32637622	1.23e-12
Cap2	Mouse	Brain	24A	32637622	2.53e-07
Cap2	Mouse	Brain	24B	32637622	2.06e-07
Cap2	Mouse	Brain	26A	32637622	1.84e-08
Cap2	Mouse	Brain	27A	32637622	1.03e-14
Cap2	Mouse	Brain	27B	32637622	1.22e-07
Cap2	Mouse	Brain	28A	32637622	1.06e-14
Cap2	Mouse	Brain	28B	32637622	8.60e-13
Cap2	Mouse	Brain	29A	32637622	1.08e-14
Cap2	Mouse	Brain	29B	32637622	1.08e-14
Cap2	Mouse	Brain	30A	32637622	6.19e-09
Cap2	Mouse	Brain	31A	32637622	4.05e-12
Cap2	Mouse	Brain	32A	32637622	5.69e-11
Cap2	Mouse	Brain	33A	32637622	6.62e-13
Cap2	Mouse	Brain	34A	32637622	1.42e-14
Cap2	Mouse	Brain	34B	32637622	1.48e-08
Cap2	Mouse	Brain	35A	32637622	2.70e-14
Cap2	Mouse	Brain	35B	32637622	2.87e-12
Cap2	Mouse	Brain	rep_1	35141374	2.02e-15
Cap2	Mouse	Brain	rep_2	35141374	1.69e-15
Cap2	Mouse	Brain	rep_3	35141374	1.64e-15
Cap2	Mouse	Brain	rep_4	35141374	1.57e-15
Cap2	Mouse	Brain	rep_5	35141374	1.47e-15
Cap2	Mouse	Brain	rep_6	35141374	1.73e-15
Cap2	Mouse	Embryo	rep_3	33188776	1.13e-14
Cap2	Mouse	Brain	rep_1	33469025	1.30e-15
Cap2	Mouse	Brain	rep_1	35027729	1.66e-15
Cap2	Mouse	Brain	rep_2	35027729	1.57e-15
Cap2	Mouse	Brain	rep_3	35027729	1.32e-15
Cap2	Mouse	Brain	rep_4	35027729	1.76e-15
Cap2	Mouse	Brain	rep_5	35027729	1.46e-15
Cap2	Mouse	Intestine	rep_1	35149721	5.87e-06
Cap2	Mouse	Brain	B02_D1	32702314	1.50e-14
Cap2	Mouse	Brain	B02_E1	32702314	1.33e-14
Cap2	Mouse	Brain	B03_C2	32702314	1.01e-13
Cap2	Mouse	Brain	B03_D2	32702314	6.48e-14
Cap2	Mouse	Brain	B04_E1	32702314	1.64e-07
Cap2	Mouse	Brain	B05_D2	32702314	5.46e-06
Cap2	Mouse	Brain	B05_E2	32702314	1.36e-06
Cap2	Mouse	Brain	B06_E1	32702314	9.92e-07
Cap2	Mouse	Brain	B07_C2	32702314	1.12e-07
Cap2	Mouse	Brain	N02_C1	32702314	2.58e-06
Cap2	Mouse	Brain	N02_D1	32702314	1.64e-07
Cap2	Mouse	Brain	N03_C2	32702314	3.71e-10
Cap2	Mouse	Brain	N03_D2	32702314	1.38e-14
Cap2	Mouse	Brain	N04_D1	32702314	2.46e-12
Cap2	Mouse	Brain	N04_E1	32702314	4.20e-13
Cap2	Mouse	Brain	N05_C2	32702314	1.34e-07
Cap2	Mouse	Brain	N05_D2	32702314	3.60e-13
Cap2	Mouse	Brain	rep_1	35210624	1.74e-15
Cap2	Mouse	Brain	rep_2	35210624	1.74e-15
Cap2	Mouse	Brain	rep_3	35210624	1.82e-15
Cap2	Mouse	Brain	rep_4	35210624	4.16e-15
Cap2	Mouse	Brain	rep_5	35210624	2.07e-15
Cap2	Mouse	Brain	rep_6	35210624	2.05e-15
Cap2	Mouse	Brain	rep_7	35210624	1.87e-15
Cap2	Mouse	Brain	OFB_ad_rep3	33083725	2.96e-03

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_C2_H&E
Brain_B03_D2_H&E
Brain_B04_E1_H&E
Brain_B05_D2_H&E
Brain_B05_E2_H&E
Brain_B06_E1_H&E
Brain_B07_C2_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_C2_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N04_E1_H&E
Brain_N05_C2_H&E
Brain_N05_D2_H&E
Brain_OFB_ad_rep3_H&E

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Spatial pattern pathway has Cap2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Cap2	GOBP_Regulation_Of_Lyase_Activity	Mouse	Spinal cord	CN94_E1	3.2e-06
Cap2	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Cap2	GOBP_Regulation_Of_Cyclase_Activity	Mouse	Spinal cord	L7bCN02_E1	6.0e-07
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Spinal cord	L7bCN02_E1	7.8e-06
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Cap2	GOBP_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	3.7e-06
Cap2	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Spinal cord	L7CN45_C1	4.7e-06
Cap2	GOBP_Regulation_Of_Adenylate_Cyclase_Activity	Mouse	Spinal cord	L7CN60_D1	2.9e-07
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Brain	rep_42	5.1e-05
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Brain	rep_1	1.3e-39
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Brain	rep_1	1.1e-31
Cap2	GOBP_Cell_Morphogenesis	Mouse	Brain	rep_1	7.6e-08
Cap2	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Cap2	GOBP_Regulation_Of_Cyclase_Activity	Mouse	Brain	rep_1	1.2e-36
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	rep_1	5.1e-20
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Brain	rep_3	2.3e-101
Cap2	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Brain	rep_3	6.8e-85
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Embryo	rep_14	6.8e-30
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Embryo	rep_14	1.0e-48
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Embryo	rep_14	1.3e-22
Cap2	GOBP_Cell_Morphogenesis	Mouse	Embryo	rep_5	2.2e-13
Cap2	GOBP_Cell_Morphogenesis	Mouse	Kidney	Nep	1.1e-16
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Kidney	rep_2	3.2e-18
Cap2	GOBP_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.7e-84
Cap2	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Cap2	GOBP_Regulation_Of_Adenylate_Cyclase_Activity	Mouse	Kidney	rep_2	1.3e-16
Cap2	GOBP_Regulation_Of_Cyclase_Activity	Mouse	Kidney	rep_2	3.0e-09
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Kidney	rep_2	2.7e-12
Cap2	GOBP_Regulation_Of_Lyase_Activity	Mouse	Liver	CN16-D1	3.1e-07
Cap2	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Liver	CN16-D2	3.2e-07
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Liver	CN16-E1	4.0e-10
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Liver	rep_15	6.0e-28
Cap2	GOBP_Regulation_Of_Adenylate_Cyclase_Activity	Mouse	Liver	rep_15	1.1e-14
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Liver	rep_16	4.7e-11
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Liver	rep_16	5.2e-08
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Lymph	MS-1	2.0e-07
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Lymph	MS-1	3.2e-10
Cap2	GOBP_Cell_Morphogenesis	Mouse	Lymph	MS-1	3.9e-13
Cap2	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Lymph	MS-1	1.1e-10
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Lung	rep_1	1.7e-11
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Brain	rep_4	2.1e-09
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Brain	rep_4	2.0e-24
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	rep_4	9.1e-14
Cap2	GOBP_Camp_Mediated_Signaling	Mouse	Brain	HP_ad_rep7	2.2e-12
Cap2	GOBP_Cell_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.4e-10
Cap2	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Cap2	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Mouse	Brain	HP_ad_rep7	4.1e-10
Cap2	GOBP_Regulation_Of_Cyclase_Activity	Mouse	Brain	HP_ad_rep7	1.4e-07
Cap2	GOBP_Activation_Of_Adenylate_Cyclase_Activity	Mouse	Brain	HP_polb_rep1	4.6e-08
Cap2	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Brain	HP_polb_rep9	6.5e-09
Cap2	GOBP_Regulation_Of_Adenylate_Cyclase_Activity	Mouse	Brain	HP_polb_rep9	8.5e-07
Cap2	GOBP_Regulation_Of_Lyase_Activity	Mouse	Brain	HP_polb_rep9	1.5e-08
Cap2	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	HP_wt_rep2	2.8e-08

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Cap2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Cap2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Cap2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Cap2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Cap2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Cap2	C0340427	Familial dilated cardiomyopathy	1	ORPHANET
Cap2	C2239176	Liver carcinoma	1	CTD_human