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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: L3hypdh (spascer ID:67217)

Gene summary for L3hypdh

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

L3hypdh

Gene ID

67217

Gene nameL-3-hydroxyproline dehydratase (trans-)
Synonyms2810055F11Rik
Cytomap12|12 C3
Type of geneprotein-coding
Descriptiontrans-L-3-hydroxyproline dehydrataseprobable proline racemasetrans-3-hydroxy-l-proline dehydratase
Modification date20220424
UniProtAcc

Q9CXA2


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
L3hypdh

GO:0016836

hydro-lyase activity

21873635

Function

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Spatial pattern events for L3hypdh

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
L3hypdhMouseKidneyIRI 340037971.52e-06
L3hypdhMouseKidneyrep_1 348531513.08e-07
L3hypdhMouseKidneyrep_3 348531514.93e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_IRI_H&E
boxplot

boxplot
Kidney_rep_1_H&E
boxplot

boxplot
Kidney_rep_3_H&E
boxplot

boxplot


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Spatial pattern pathway has L3hypdh envolved


SymbolPathwaySpeciesTissue typeReplicationP-value

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L3hypdh function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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L3hypdh function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for L3hypdh envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for L3hypdh

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for L3hypdh

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
L3hypdhC0023893Liver Cirrhosis, Experimental1CTD_human